Mund, Elias, Salem, Johannes, Kreipe, Hans H. and Hussein, Kais (2022). Clinically latent and autopsy-verified inflammatory disorders and malignant tumours in transplant patients. J. Clin. Pathol., 75 (2). S. 112 - 117. LONDON: BMJ PUBLISHING GROUP. ISSN 1472-4146
Full text not available from this repository.Abstract
Aims The number of clinical autopsies decreases while the rate of missed relevant diagnoses is known to be 2%-20%. In this study, we focused on postmortem examinations of patients after transplantation of solid organs. Methods A total of 122 cases were assessed for this study. Transplant organs included liver (LiTx; n=42/122, 34%), heart (n=8/122, 7%), lungs (n=32/122, 26%), kidney (KTx; n=38/122, 31%) and KTx+LiTx (n=2/122, 2%). Results The most frequent autopsy-verified causes of death were cardiac or respiratory failure (together n=85/122, 70%). The frequency of malignant tumours that were identified at autopsy was 5% (n=6/122). In 3% (n=4/122) of cases, Goldman class I discrepancies between clinical diagnosis and autopsy findings were identified. Conclusions The rate of missed relevant diagnoses might be relatively low, but these cases nevertheless refute the contention that modern diagnostic techniques negate the need for autopsies in patients who died after transplantation.
Item Type: | Journal Article | ||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-666317 | ||||||||||||||||||||
DOI: | 10.1136/jclinpath-2020-207080 | ||||||||||||||||||||
Journal or Publication Title: | J. Clin. Pathol. | ||||||||||||||||||||
Volume: | 75 | ||||||||||||||||||||
Number: | 2 | ||||||||||||||||||||
Page Range: | S. 112 - 117 | ||||||||||||||||||||
Date: | 2022 | ||||||||||||||||||||
Publisher: | BMJ PUBLISHING GROUP | ||||||||||||||||||||
Place of Publication: | LONDON | ||||||||||||||||||||
ISSN: | 1472-4146 | ||||||||||||||||||||
Language: | English | ||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/66631 |
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