Mund, Elias, Salem, Johannes, Kreipe, Hans H. and Hussein, Kais (2022). Clinically latent and autopsy-verified inflammatory disorders and malignant tumours in transplant patients. J. Clin. Pathol., 75 (2). S. 112 - 117. LONDON: BMJ PUBLISHING GROUP. ISSN 1472-4146

Full text not available from this repository.

Abstract

Aims The number of clinical autopsies decreases while the rate of missed relevant diagnoses is known to be 2%-20%. In this study, we focused on postmortem examinations of patients after transplantation of solid organs. Methods A total of 122 cases were assessed for this study. Transplant organs included liver (LiTx; n=42/122, 34%), heart (n=8/122, 7%), lungs (n=32/122, 26%), kidney (KTx; n=38/122, 31%) and KTx+LiTx (n=2/122, 2%). Results The most frequent autopsy-verified causes of death were cardiac or respiratory failure (together n=85/122, 70%). The frequency of malignant tumours that were identified at autopsy was 5% (n=6/122). In 3% (n=4/122) of cases, Goldman class I discrepancies between clinical diagnosis and autopsy findings were identified. Conclusions The rate of missed relevant diagnoses might be relatively low, but these cases nevertheless refute the contention that modern diagnostic techniques negate the need for autopsies in patients who died after transplantation.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Mund, EliasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Salem, JohannesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kreipe, Hans H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hussein, KaisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-666317
DOI: 10.1136/jclinpath-2020-207080
Journal or Publication Title: J. Clin. Pathol.
Volume: 75
Number: 2
Page Range: S. 112 - 117
Date: 2022
Publisher: BMJ PUBLISHING GROUP
Place of Publication: LONDON
ISSN: 1472-4146
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SOLID-ORGAN TRANSPLANTATION; INFECTIOUS-DISEASES; RECIPIENTS ANALYSIS; DISCREPANCIES; DIAGNOSES; CANCER; DEATH; LIVER; LIPOSARCOMA; ORIGINMultiple languages
PathologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/66631

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item