Universität zu Köln

Ratiu, Oana, Ratiu, Dominik, Mallmann, Peter, Di Liberto, Alexander, Ertan, A. Kubilay, Morgenstern, Bernd, Mallmann, Michael R., Ludwig, Sebastian, Gruettner, Berthold, Eichler, Christian, Thangarajah, Fabinshy, Gilman, Elena and Abel, Judith S. (2022). Oral Misoprostol for the Induction of Labor: Comparison of Different Dosage Schemes With Respect to Maternal and Fetal Outcome in Patients Beyond 34 Weeks of Pregnancy. In Vivo, 36 (3). S. 1285 - 1290. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7549

Full text not available from this repository.

Abstract

Background/Aim: Labor is induced in 1 out of 5 pregnancies. This is why we aimed to compare two different protocols of orally administered misoprostol for the induction of labor (IOL), with special regard to maternal and fetal outcome, delivery mode and duration. Patients and Methods: One hundred and twenty four patients with a medical indication for IOL were divided into two groups: Group A (n=63), which initially received 50 ,ug misoprostol escalated to 100 and, subsequently, to 200 ,ug every 4 h with a daily maximum of 600,ug, between 11/2007 and 01/2008; and Group B (n=61), which initially received 25 ,ug misoprostol followed by 100 ,ug every 4 h with a daily maximum of 300 ,ug, between 12/2009 and 04/2010. Results: The mean administration-delivery interval was significantly lower in Group A (19.0 h) compared to Group B (27.1 h, p<0.05). Overall caesarean section rate, average birth weight, APGAR score, umbilical cord pH and meconiumstained fluid rates were similar between both groups. Conclusion: A higher dosage protocol of orally administered misoprostol significantly reduces the mean induction-delivery interval without increasing the risk for an adverse maternal or fetal outcome.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ratiu, Oana UNSPECIFIED UNSPECIFIED UNSPECIFIED Ratiu, Dominik UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Di Liberto, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Ertan, A. Kubilay UNSPECIFIED UNSPECIFIED UNSPECIFIED Morgenstern, Bernd UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Michael R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ludwig, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Gruettner, Berthold UNSPECIFIED UNSPECIFIED UNSPECIFIED Eichler, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Thangarajah, Fabinshy UNSPECIFIED UNSPECIFIED UNSPECIFIED Gilman, Elena UNSPECIFIED UNSPECIFIED UNSPECIFIED Abel, Judith S. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-667580
DOI:	10.21873/invivo.12828
Journal or Publication Title:	In Vivo
Volume:	36
Number:	3
Page Range:	S. 1285 - 1290
Date:	2022
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7549
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language VAGINAL MISOPROSTOL; TERM; DINOPROSTONE; CATHETER Multiple languages Medicine, Research & Experimental Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66758