Universität zu Köln

Verbraecken, Johan ORCID: 0000-0002-6087-678X, Dieltjens, Marijke ORCID: 0000-0002-5822-1960, de Beeck, Sara Op, Vroegop, Anneclaire ORCID: 0000-0001-7538-2021, Braem, Marc, Vanderveken, Olivier and Randerath, Winfried ORCID: 0000-0002-5010-8461 (2022). Non-CPAP therapy for obstructive sleep apnoea. Breathe, 18 (3). SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. ISSN 2073-4735

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Abstract

Treatment of obstructive sleep apnoea in adults is evolving, from a one treatment fits all to a more individualised approach. The spectrum of treatment options is broad and heterogeneous, including conservative, technological and pharmaceutical modalities. This raises the questions of which patients these modalities might be useful for, and if there are specific criteria for single or combined treatment. The most commonly used non-CPAP treatment is a mandibular advancement device. Furthermore, it appears from the available evidence that upper airway surgery, bariatric surgery, and maxillomandibular advancement can be effective in particular patient groups and should be indicated more readily in clinical practice. Technically, a tracheotomy is the most effective surgical treatment, but is not socially acceptable and is associated with major side-effects. Other treatment options are emerging, like positional therapy, hypoglossal nerve stimulation, and myofunctional exercises. Drug therapy is also promising when pathophysiological traits are considered. The range of currently available treatment options will be discussed in this review, with emphasis on the selection of appropriate patients, therapeutic efficacy and compliance, and reference to recent guidelines. In the selection process, routine application of drug-induced sleep endoscopy to assess the site(s) of collapse during sleep can increase the success rate of both surgical interventions and oral appliance therapy.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Verbraecken, Johan UNSPECIFIED orcid.org/0000-0002-6087-678X UNSPECIFIED Dieltjens, Marijke UNSPECIFIED orcid.org/0000-0002-5822-1960 UNSPECIFIED de Beeck, Sara Op UNSPECIFIED UNSPECIFIED UNSPECIFIED Vroegop, Anneclaire UNSPECIFIED orcid.org/0000-0001-7538-2021 UNSPECIFIED Braem, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Vanderveken, Olivier UNSPECIFIED UNSPECIFIED UNSPECIFIED Randerath, Winfried UNSPECIFIED orcid.org/0000-0002-5010-8461 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-668653
DOI:	10.1183/20734735.0164-2022
Journal or Publication Title:	Breathe
Volume:	18
Number:	3
Date:	2022
Publisher:	EUROPEAN RESPIRATORY SOC JOURNALS LTD
Place of Publication:	SHEFFIELD
ISSN:	2073-4735
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ORAL APPLIANCE THERAPY; MANDIBULAR ADVANCEMENT DEVICES; UPPER-AIRWAY STIMULATION; TENNIS BALL TECHNIQUE; SURGICAL MODIFICATIONS; CLINICAL-PRACTICE; POSITION TRAINER; CONTROLLED-TRIAL; SELECTION TOOL; ENDOSCOPY Multiple languages Respiratory System Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66865