Universität zu Köln

Lu, Jian, Wen, Chi-Kuang and Groth, Georg ORCID: 0000-0002-1806-9861 (2022). New Insights into Phase Separation Processes and Membraneless Condensates of EIN2. Plants-Basel, 11 (16). BASEL: MDPI. ISSN 2223-7747

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Abstract

Recent technological advances allow us to resolve molecular processes in living cells with high spatial and temporal resolution. Based on these technological advances, membraneless intracellular condensates formed by reversible functional aggregation and phase separation have been identified as important regulatory modules in diverse biological processes. Here, we present bioinformatic and cellular studies highlighting the possibility of the involvement of the central activator of ethylene responses EIN2 in such cellular condensates and phase separation processes. Our work provides insight into the molecular type (identity) of the observed EIN2 condensates and on potential intrinsic elements and sequence motifs in EIN2-C that may regulate condensate formation and dynamics.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lu, Jian UNSPECIFIED UNSPECIFIED UNSPECIFIED Wen, Chi-Kuang UNSPECIFIED UNSPECIFIED UNSPECIFIED Groth, Georg UNSPECIFIED orcid.org/0000-0002-1806-9861 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-670132
DOI:	10.3390/plants11162149
Journal or Publication Title:	Plants-Basel
Volume:	11
Number:	16
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2223-7747
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SET ENRICHMENT ANALYSIS; RNA-BINDING; IN-VIVO; ETHYLENE; TRANSLATION; ARABIDOPSIS; INSENSITIVITY; REGULATOR; PROTEINS; DOMAINS Multiple languages Plant Sciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67013