Universität zu Köln

Felbor, Ute, Buelow, Robin, Schmutzler, Rita K. and Rath, Matthias ORCID: 0000-0002-7834-4650 (2022). Hereditary Breast and Ovarian Cancer Service in Sparsely Populated Western Pomerania. Healthcare, 10 (10). BASEL: MDPI. ISSN 2227-9032

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Abstract

The German Consortium Hereditary Breast and Ovarian Cancer (GC-HBOC) consists of 23 academic centers striving to provide high-quality regional care for affected individuals and healthy at-risk family members. According to the standard operating procedures defined by the GC-HBOC, a Familial Breast and Ovarian Cancer Center was implemented at the University Medicine Greifswald over a four-year period from 2018 to 2021, despite the COVID-19 pandemic. Genetic analyses were performed in a total of 658 individuals, including 41 males, which paved the way to local annual risk-adapted breast cancer surveillance for 91 women and prophylactic surgery for 34 women in 2021. Our experience in the North Eastern part of Germany demonstrates that it is possible to establish a high-risk breast and ovarian cancer service even in a sparsely populated region. Major facilitators are the interdisciplinary collaboration of dedicated local experts, the support of the GC-HBOC, fruitful clinical and scientific cooperations and the use of technical improvements. As a blueprint, our project report may help to further expand the network of specialized and knowledge-generating care for HBOC families.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Felbor, Ute UNSPECIFIED UNSPECIFIED UNSPECIFIED Buelow, Robin UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmutzler, Rita K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rath, Matthias UNSPECIFIED orcid.org/0000-0002-7834-4650 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-673525
DOI:	10.3390/healthcare10102021
Journal or Publication Title:	Healthcare
Volume:	10
Number:	10
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2227-9032
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GERMLINE MUTATIONS; GERMAN CONSORTIUM; SEQUENCE VARIANTS; RISK; PREVALENCE; GENES Multiple languages Health Care Sciences & Services; Health Policy & Services Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67352