Universität zu Köln

Sack, Carolin, Ferrari, Nina, Friesen, David, Haas, Fabiola, Klaudius, Marlen, Schmidt, Lisa, Torbahn, Gabriel ORCID: 0000-0003-1463-3119, Wulff, Hagen ORCID: 0000-0001-8814-5228 and Joisten, Christine (2022). Health Risks of Sarcopenic Obesity in Overweight Children and Adolescents: Data from the CHILT III Programme (Cologne). J. Clin. Med., 11 (1). BASEL: MDPI. ISSN 2077-0383

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Abstract

Sarcopenic obesity is increasingly found in youth, but its health consequences remain unclear. Therefore, we studied the prevalence of sarcopenia and its association with cardiometabolic risk factors as well as muscular and cardiorespiratory fitness using data from the German Children's Health InterventionaL Trial (CHILT III) programme. In addition to anthropometric data and blood pressure, muscle and fat mass were determined with bioelectrical impedance analysis. Sarcopenia was classified via muscle-to-fat ratio. A fasting blood sample was taken, muscular fitness was determined using the standing long jump, and cardiorespiratory fitness was determined using bicycle ergometry. Of the 119 obese participants included in the analysis (47.1% female, mean age 12.2 years), 83 (69.7%) had sarcopenia. Affected individuals had higher gamma-glutamyl transferase, higher glutamate pyruvate transaminase, higher high-sensitivity C-reactive protein, higher diastolic blood pressure, and lower muscular and cardiorespiratory fitness (each p < 0.05) compared to participants who were 'only' obese. No differences were found in other parameters. In our study, sarcopenic obesity was associated with various disorders in children and adolescents. However, the clinical value must be tested with larger samples and reference populations to develop a unique definition and appropriate methods in terms of identification but also related preventive or therapeutic approaches.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Sack, Carolin UNSPECIFIED UNSPECIFIED UNSPECIFIED Ferrari, Nina UNSPECIFIED UNSPECIFIED UNSPECIFIED Friesen, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Haas, Fabiola UNSPECIFIED UNSPECIFIED UNSPECIFIED Klaudius, Marlen UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Torbahn, Gabriel UNSPECIFIED orcid.org/0000-0003-1463-3119 UNSPECIFIED Wulff, Hagen UNSPECIFIED orcid.org/0000-0001-8814-5228 UNSPECIFIED Joisten, Christine UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-677372
DOI:	10.3390/jcm11010277
Journal or Publication Title:	J. Clin. Med.
Volume:	11
Number:	1
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2077-0383
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SKELETAL-MUSCLE MASS; METABOLIC SYNDROME; CHILDHOOD OBESITY; BODY-COMPOSITION; FAT; DEFINITIONS; PREVALENCE; EQUATIONS; ADULTHOOD; CONSENSUS Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67737