Universität zu Köln

Pers, Daniel ORCID: 0000-0002-9704-221X, Buchta, Thomas ORCID: 0000-0002-7040-8381, Oezueak, Orhan, Roth, Siegfried and Lynch, Jeremy A. (2022). Expression and Function of Toll Pathway Components in the Early Development of the Wasp Nasonia vitripennis. J. Dev. Biol., 10 (1). BASEL: MDPI. ISSN 2221-3759

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Abstract

The Toll signaling pathway is the main source of embryonic DV polarity in the fly Drosophila melanogaster. This pathway appears to have been co-opted from an ancestral innate immunity system within the insects and has been deployed in different ways among insect taxa. Here we report the expression and function of homologs of the important components of the D. melanogaster Toll pathway in the wasp Nasonia vitripennis. We found homologs for all the components; many components had one or more additional paralogs in the wasp relative the fly. We also found significant deviations in expression patterns of N. vitripennis homologs. Finally, we provide some preliminary functional analyses of the N. vitripennis homologs, where we find a mixture of conservation and divergence of function.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Pers, Daniel UNSPECIFIED orcid.org/0000-0002-9704-221X UNSPECIFIED Buchta, Thomas UNSPECIFIED orcid.org/0000-0002-7040-8381 UNSPECIFIED Oezueak, Orhan UNSPECIFIED UNSPECIFIED UNSPECIFIED Roth, Siegfried UNSPECIFIED UNSPECIFIED UNSPECIFIED Lynch, Jeremy A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-678936
DOI:	10.3390/jdb10010007
Journal or Publication Title:	J. Dev. Biol.
Volume:	10
Number:	1
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2221-3759
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DORSOVENTRAL AXIS FORMATION; DORSAL-VENTRAL POLARITY; REL PROTEIN DORSAL; DROSOPHILA EMBRYO; SERINE-PROTEASE; NUCLEAR IMPORT; DEGRADATION ESTABLISHES; SIGNAL-TRANSDUCTION; ACTIVITY GRADIENT; KINASE PELLE Multiple languages Developmental Biology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/67893