Universität zu Köln

Arzt, Michael, Oldenburg, Olaf, Graml, Andrea, Schnepf, Jurgen, Erdmann, Erland ORCID: 0000-0002-9887-3736, Teschler, Helmut, Schoebel, Christoph and Woehrle, Holger ORCID: 0000-0001-6588-5039 (2022). Prevalence and predictors of sleep-disordered breathing in chronic heart failure: the SchlaHF-XT registry. ESC Heart Fail., 9 (6). S. 4100 - 4112. SAN FRANCISCO: WILEY PERIODICALS, INC. ISSN 2055-5822

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Abstract

Aims Heart failure with preserved ejection fraction (HFpEF) is a condition with increasing prevalence. Sleep-disordered breathing (SDB) is an important co-morbidity in HFpEF. The SchlaHF-XT registry evaluated the sex-specific prevalence and predictors of SOB, including obstructive (OSA) and central sleep apnoea, in patients with HFpEF compared with heart failure with mildly reduced (HFmrEF) or reduced (HFrEF) ejection fraction. Methods and results Consecutive adults with chronic heart failure treated according to current guidelines were enrolled. The presence of moderate-to-severe SDB (apnoea-hypopnoea index >= 15/h) was determined using Type 3 polygraphic devices. Of 3289 patients included, 2032 had HFpEF, 559 had HFmrEF, and 698 had HFrEF, of whom 34, 21, 23, and 42%, respectively, were female. Prevalence of SDB in HFpEF was high, but significantly lower than in HFmrEF or HFrEF (36% vs. 41 and 48%, respectively). Rates of SDB in males and females were 41 and 28% in HFpEF, 44 and 30% in HFmrEF, and 50 and 40% in HFrEF. The proportion of males and females with SDB who had OSA was significantly greater in those with HFpEF vs. HFrEF. Male sex, older age, higher body mass index, and New York Heart Association functional Class III/IV were significant predictors of moderate-to-severe SDB in HFpEF patients. Conclusions Prevalence of SDB in HFpEF was high, but lower than in patients with HFmrEF or HFrEF. Moderate-to-severe SDB occurred more frequently in males than in females across the whole spectrum of heart failure. In both sexes, the proportion of OSA in SDB patients with HFpEF was higher than in those with HFrEF.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Arzt, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Oldenburg, Olaf UNSPECIFIED UNSPECIFIED UNSPECIFIED Graml, Andrea UNSPECIFIED UNSPECIFIED UNSPECIFIED Schnepf, Jurgen UNSPECIFIED UNSPECIFIED UNSPECIFIED Erdmann, Erland UNSPECIFIED orcid.org/0000-0002-9887-3736 UNSPECIFIED Teschler, Helmut UNSPECIFIED UNSPECIFIED UNSPECIFIED Schoebel, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Woehrle, Holger UNSPECIFIED orcid.org/0000-0001-6588-5039 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-681758
DOI:	10.1002/ehf2.14027
Journal or Publication Title:	ESC Heart Fail.
Volume:	9
Number:	6
Page Range:	S. 4100 - 4112
Date:	2022
Publisher:	WILEY PERIODICALS, INC
Place of Publication:	SAN FRANCISCO
ISSN:	2055-5822
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ADAPTIVE SERVO-VENTILATION; EUROPEAN-SOCIETY; APNEA; DIAGNOSIS; CLASSIFICATION; ASSOCIATION; GUIDELINES; PROGNOSIS; IMPACT; ESC Multiple languages Cardiac & Cardiovascular Systems Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/68175