Kessner, Rivka, Sommer, Jennifer, Hokamp, Nils Grosse, Laukamp, Kai R. and Nayate, Ameya (2023). Virtual versus true non-contrast images of the brain from spectral detector CT: comparison of attenuation values and image quality. Acta Radiol., 64 (2). S. 776 - 784. LONDON: SAGE PUBLICATIONS LTD. ISSN 1600-0455

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Abstract

Background Prior studies focused on utilization of dual-energy computed tomography (DECT) to better detect intracranial pathology and to reduce artifacts. It is still unclear whether virtual non-contrast (VNC) images of DECT can replace true non-contrast (TNC) images. Purpose To compare attenuation values and image quality of VNC images to TNC images of the brain, obtained using spectral detector CT (SDCT). Material and Methods We retrospectively evaluated patients that underwent head CT with and without contrast material, on a SDCT scanner at our institution (n = 33). The attenuation values of different brain structures were obtained from TNC images, the conventional images of the post-contrast exams (n = 16) or the CT angiography (CTA) (n = 17), and the derived VNC images. In total, 591 regions of interest were obtained, including white and gray matter. Two neuroradiologists independently evaluated the image quality of the VNC and TNC images, using a 5-point Likert scale. Results The mean difference between the attenuation values on the VNC versus the TNC images was <4 HU for almost all the structures. The difference reached statistical significance (P < 0.05) for the deep gray structures but not for the white matter. The image quality score of the TNC images was 5 in all the patients (excellent gray-white matter differentiation). The scores of the VNC images differed between post-contrast and CTA examinations, with means of 4.9 +/- 0.3 (excellent) and 3.2 +/- 0.4 (fair), respectively (P < 0.001). Conclusion Our results show minor differences between attenuation values of different brain structures on VNC versus TNC images of SDCT.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kessner, RivkaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sommer, JenniferUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hokamp, Nils GrosseUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laukamp, Kai R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nayate, AmeyaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-682495
DOI: 10.1177/02841851221093763
Journal or Publication Title: Acta Radiol.
Volume: 64
Number: 2
Page Range: S. 776 - 784
Date: 2023
Publisher: SAGE PUBLICATIONS LTD
Place of Publication: LONDON
ISSN: 1600-0455
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
DUAL-ENERGY CT; ANGIOGRAPHY; HEMORRHAGE; DECTMultiple languages
Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/68249

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