Universität zu Köln

Galldiks, Norbert, Wollring, Michael, Werner, Jan-Michael ORCID: 0000-0001-7147-4594, Friedrich, Michel ORCID: 0000-0003-2409-4614, Fink, Gereon R. ORCID: 0000-0002-8230-1856, Langen, Karl-Josef and Lohmann, Philipp (2022). An updated review on the diagnosis and assessment of post-treatment relapse in brain metastases using PET. Expert Rev. Neurother., 22 (11-12). S. 915 - 922. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-8360

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Abstract

IntroductionBrain metastases in patients with extracranial cancer are typically associated with increased morbidity and mortality. Stereotactic radiotherapy and immunotherapy using checkpoint inhibitors currently are essential in brain metastases treatment. Since conventional contrast-enhanced MRI alone cannot reliably differentiate between treatment-induced changes and brain metastasis relapse, several studies investigated the role of PET imaging and, more recently, radiomics, based on routinely acquired PET images, to overcome this clinically relevant challenge.Areas coveredThe current literature on PET imaging, including radiomics, in patients with brain metastases, focusing on the diagnosis and assessment of post-treatment relapse, is summarized.Expert opinionAvailable data suggest that imaging parameters, including radiomics features, mainly derived from amino acid PET, are helpful for diagnosis and assessment of post-treatment relapse in patients with brain metastases.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Galldiks, Norbert UNSPECIFIED UNSPECIFIED UNSPECIFIED Wollring, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Werner, Jan-Michael UNSPECIFIED orcid.org/0000-0001-7147-4594 UNSPECIFIED Friedrich, Michel UNSPECIFIED orcid.org/0000-0003-2409-4614 UNSPECIFIED Fink, Gereon R. UNSPECIFIED orcid.org/0000-0002-8230-1856 UNSPECIFIED Langen, Karl-Josef UNSPECIFIED UNSPECIFIED UNSPECIFIED Lohmann, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-683894
DOI:	10.1080/14737175.2022.2162880
Journal or Publication Title:	Expert Rev. Neurother.
Volume:	22
Number:	11-12
Page Range:	S. 915 - 922
Date:	2022
Publisher:	TAYLOR & FRANCIS LTD
Place of Publication:	ABINGDON
ISSN:	1744-8360
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FDG-PET; STEREOTACTIC RADIOSURGERY; RADIATION-INJURY; O-(2-F-18-FLUOROETHYL)-L-TYROSINE PET; INDUCED NECROSIS; GAMMA-KNIFE; RECURRENT; RADIOMICS; TUMOR; DIFFERENTIATION Multiple languages Clinical Neurology; Pharmacology & Pharmacy Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/68389