Universität zu Köln

Saha, Shekhar, Ali, Ahmad, Schnackenburg, Philipp, Horke, Konstanze Maria, Oberbach, Andreas, Schlichting, Nadine, Sadoni, Sebastian ORCID: 0000-0002-1796-4434, Rizas, Konstantinos, Braun, Daniel, Luehr, Maximilian ORCID: 0000-0002-0645-1764, Bagaev, Erik, Hagl, Christian and Joskowiak, Dominik (2022). Surgery for Aortic Prosthetic Valve Endocarditis in the Transcatheter Era. J. Clin. Med., 11 (12). BASEL: MDPI. ISSN 2077-0383

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Abstract

Objectives: As surgical experience with infective endocarditis following transcatheter aortic valve replacement is scarce, this study compared the perioperative and short-term outcomes of patients suffering from endocarditis following surgical aortic valve replacement and transcatheter aortic valve replacement. Methods: Between January 2013 and December 2020, 468 consecutive patients were admitted to our center for surgery for IE. Among them, 98 were operated on for endocarditis following surgical aortic valve replacement and 22 for endocarditis following transcatheter aortic valve replacement. Results: The median EuroSCORE II (52.1 (40.6-62.0) v/s 45.4 (32.6-58.1), p = 0.207) and STS-PROM (1.8 (1.6-2.1) v/s 1.9 (1.4-2.2), p = 0.622) were comparable. Endocarditis following transcatheter aortic valve replacement accounted for 13.7% of the aortic prosthetic valve endocarditis between 2013 and 2015; this increased to 26.9% in the years 2019 and 2020.Concomitant procedures were performed in 35 patients (29.2%). The operative mortality was 26.5% in the endocarditis following surgical aortic valve replacement group and 9.1% in the endocarditis following transcatheter aortic valve replacement group (p = 0.098). Upon follow-up, survival at 6 months was found to be 98% in the group with endocarditis following surgical aortic valve replacement and 89% in the group with endocarditis following transcatheter aortic valve replacement (p = 0.081). Conclusions: Patients suffering from endocarditis following surgical aortic valve replacement and transcatheter aortic valve replacement present with comparable risk profiles and can be surgically treated with comparable results. Surgery as a curative option should not be rejected even in this intermediate-risk cohort.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Saha, Shekhar UNSPECIFIED UNSPECIFIED UNSPECIFIED Ali, Ahmad UNSPECIFIED UNSPECIFIED UNSPECIFIED Schnackenburg, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Horke, Konstanze Maria UNSPECIFIED UNSPECIFIED UNSPECIFIED Oberbach, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Schlichting, Nadine UNSPECIFIED UNSPECIFIED UNSPECIFIED Sadoni, Sebastian UNSPECIFIED orcid.org/0000-0002-1796-4434 UNSPECIFIED Rizas, Konstantinos UNSPECIFIED UNSPECIFIED UNSPECIFIED Braun, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Luehr, Maximilian UNSPECIFIED orcid.org/0000-0002-0645-1764 UNSPECIFIED Bagaev, Erik UNSPECIFIED UNSPECIFIED UNSPECIFIED Hagl, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Joskowiak, Dominik UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-685301
DOI:	10.3390/jcm11123418
Journal or Publication Title:	J. Clin. Med.
Volume:	11
Number:	12
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2077-0383
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SURGICAL-TREATMENT; CARDIAC-SURGERY; MORTALITY Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/68530