Universität zu Köln

Liu, Li, Song, Wen, Huang, Shijia, Jiang, Kai ORCID: 0000-0001-9901-5293, Moriwaki, Yoshitaka ORCID: 0000-0003-0448-9790, Wang, Yichuan, Men, Yongfan, Zhang, Dan, Wen, Xing ORCID: 0000-0002-9322-2272, Han, Zhifu, Chai, Jijie and Guo, Hongwei (2022). Extracellular pH sensing by plant cell-surface peptide-receptor complexes. Cell, 185 (18). S. 3341 - 3370. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Full text not available from this repository.

Abstract

The extracellular pH is a vital regulator of various biological processes in plants. However, how plants perceive extracellular pH remains obscure. Here, we report that plant cell-surface peptide-receptor com-plexes can function as extracellular pH sensors. We found that pattern-triggered immunity (PTI) dramatically alkalinizes the acidic extracellular pH in root apical meristem (RAM) region, which is essential for root meri-stem growth factor 1 (RGF1)-mediated RAM growth. The extracellular alkalinization progressively inhibits the acidic-dependent interaction between RGF1 and its receptors (RGFRs) through the pH sensor sulfotyrosine. Conversely, extracellular alkalinization promotes the alkaline-dependent binding of plant elicitor peptides (Peps) to its receptors (PEPRs) through the pH sensor Glu/Asp, thereby promoting immunity. A domain swap between RGFR and PEPR switches the pH dependency of RAM growth. Thus, our results reveal a mechanism of extracellular pH sensing by plant peptide-receptor complexes and provide insights into the extracellular pH-mediated regulation of growth and immunity in the RAM.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Liu, Li UNSPECIFIED UNSPECIFIED UNSPECIFIED Song, Wen UNSPECIFIED UNSPECIFIED UNSPECIFIED Huang, Shijia UNSPECIFIED UNSPECIFIED UNSPECIFIED Jiang, Kai UNSPECIFIED orcid.org/0000-0001-9901-5293 UNSPECIFIED Moriwaki, Yoshitaka UNSPECIFIED orcid.org/0000-0003-0448-9790 UNSPECIFIED Wang, Yichuan UNSPECIFIED UNSPECIFIED UNSPECIFIED Men, Yongfan UNSPECIFIED UNSPECIFIED UNSPECIFIED Zhang, Dan UNSPECIFIED UNSPECIFIED UNSPECIFIED Wen, Xing UNSPECIFIED orcid.org/0000-0002-9322-2272 UNSPECIFIED Han, Zhifu UNSPECIFIED UNSPECIFIED UNSPECIFIED Chai, Jijie UNSPECIFIED UNSPECIFIED UNSPECIFIED Guo, Hongwei UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-687549
DOI:	10.1016/j.cell.2022.07.012
Journal or Publication Title:	Cell
Volume:	185
Number:	18
Page Range:	S. 3341 - 3370
Date:	2022
Publisher:	CELL PRESS
Place of Publication:	CAMBRIDGE
ISSN:	1097-4172
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PATTERN-RECOGNITION RECEPTORS; STRUCTURAL BASIS; ENDOGENOUS PEPTIDE; LIGAND PERCEPTION; LATERAL ROOT; ARABIDOPSIS; GROWTH; AUXIN; DEFENSE; SIGNAL Multiple languages Biochemistry & Molecular Biology; Cell Biology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/68754