Donas, Konstantinos P., Taneva, Gergana T., Pitoulias, Georgios A., Jomha, Amer, Schroder, Martin, Psyllas, Anastasios, Scali, Salvatore, Abu Bakr, Nizar and Registry, Morpheas (2022). Technical performance and reproducibility following rotational atherectomy of femoropopliteal artery occlusive lesions: analysis of the multicenter MORPHEAS Registry. J. Cardiovasc. Surg., 63 (1). S. 13 - 20. TURIN: EDIZIONI MINERVA MEDICA. ISSN 1827-191X

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Abstract

BACKGROUND: The purpose of this study was to define patient and anatomical factors associated with technical results specific to rotational atherectomy. Controversy exists surrounding appropriate utilization of atherectomy to treat femoral-popliteal atherosclerosis. Importantly, the existence of different atherectomy devices and lack of technical reports highlighting variables that impact outcomes obscures the ability to assess perioperative performance. METHODS: The nonindustry sponsored, Multicentric National Registry on the use of rotational atherectomy in femoral-popliteal occlusive atherosclerotic disease (MORPHEAS) database was queried. The MORPHEAS investigators included experienced providers at four centers who previously had not utilized rotational atherectomy. The primary endpoint was flow-limiting dissection and/or >50% recoil resulting in stentplacement while a secondary endpoint included peripheral thromboembolism incidence. RESULTS: One hundred thirteen patients were enrolled. Only femoropopliteal occlusions were included in the analysis and anatomic distribution and calcification severity were depicted separately. The most common adjunctive therapy was drug-coated balloon angioplasty (84%; N.=96). Flow-limiting dissection was identified in 16% (N.=18) and thromboembolism occurred in 4% (N.=4). Diabetes increased risk of thromboembolism (P=0.03) while lesion length >8.0 cm (P=0.07) and SFA-popliteal adductor canal location (P=0.01) were associated with flow-limiting dissection. In multivariable analysis, SFA-popliteal adductor canal occlusion had a 4.7-fold risk of perioperative complications (OR=4.7, 95%CI: 1.1-21.0; P=0.04). CONCLUSIONS: Rotational atherectomy was characterized by reproducible performance among four centers; however, diabetic patients, as well as those with long-segment, heavily calcified SFA-popliteal adductor canal occlusion present greatest risk of complications. (Cite this article as: Donas KP, Taneva GT, Pitoulias GA, Jomha A, Schr delta der M, Psyllas A, et al.; MORPHEAS Registry. Technical performance and reproducibility following rotational atherectomy of femoropopliteal artery occlusive lesions: analysis of the multicenter MORPHEAS Registry. J Cardiovasc Surg 2022;63

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Donas, Konstantinos P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Taneva, Gergana T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pitoulias, Georgios A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jomha, AmerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroder, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Psyllas, AnastasiosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scali, SalvatoreUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Abu Bakr, NizarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Registry, MorpheasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-687912
DOI: 10.23736/S0021-9509.21.12159-7
Journal or Publication Title: J. Cardiovasc. Surg.
Volume: 63
Number: 1
Page Range: S. 13 - 20
Date: 2022
Publisher: EDIZIONI MINERVA MEDICA
Place of Publication: TURIN
ISSN: 1827-191X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
IMPACTMultiple languages
Cardiac & Cardiovascular Systems; Surgery; Peripheral Vascular DiseaseMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/68791

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