HIV First Diagnoses in Germany in 2014-A Regional Analysis - Kölner UniversitätsPublikationsServer

Schleenvoigt, Benjamin Thomas, Ankert, Juliane, Stocker, Hartmut, Stoehr, Albrecht, Lehmann, Clara, Schulz, Christian, Wesselmann, Hans, Bickel, Markus, Haberl, Annette, Degen, Olaf, Pletz, Mathias Wilhelm, Seybold, Ulrich and Stephan, Christoph ORCID: 0000-0003-3777-9006 (2022). HIV First Diagnoses in Germany in 2014-A Regional Analysis. Gesundheitswesen, 84 (11). S. E45 - 8. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-4421

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DOI:10.1055/a-1665-6762

Abstract

Background Information on testing units in health care is scarce, particularly the group of late-presenters among the HIV-first diagnoses is still a challenge in Germany. Aim Analysis of the impact of testing units on and reasons for the prevalence of HIV-first diagnoses and late presentation, taking 2014 for illustrative purposes. Material and Methods Cross-sectional analysis of all individuals, treated in the Network HIV-Regional who were first diagnosed with HIV in 2014; patient characteristics, demographic and clinical data, including information on HIV testing were collected retrospectively and in a decentralised manner, pseudonymized and statistically evaluated. Results A total of 971 individuals with HIV-first diagnosis from 31 specialised care centres throughout Germany (15 hospitals, 16 private practices) represented 27.5% of all National HIV-first diagnoses -registrations from Robert Koch Institute for 2014, with similar results for CD4-cell count and HIV-transmission risk. The most common test site was a hospital (34.8%), followed by the office of a family doctor (19.6%) and medical specialist (16.1%). If the first diagnosis was established in hospital, then the patients were on average older than those tested on an ambulant care basis (42 vs. 37 years, p=0.001); moreover, the HI-viral load was higher (585 vs. 270 thousand copies/mL, p<0.001) and the CD4-cell count lower (265 vs. 414/mu L, p<0.001). In 208/971 individuals with first diagnosis, at least one AIDS-defining disease was found, most frequently pneumocystis-pneumonia (43.8%), candidiasis (36.5%) and Kaposi sarcoma (10.6%). A regional comparison revealed that in eastern Germany, for first diagnosed HIV-patients were younger, had a higher HIV-RNA viral load and also more often clinical AIDS. Conclusion This analysis of HIV-Regional for 2014 enables a deeper insight into HIV first diagnoses, on the eve of the introduction of important prevention tools in Germany, e. g., HIV home testing and pre-exposure prophylaxis. This cross-sectional analysis was representative for Germany and underscores the importance of specialised hospitals, in particular for eastern Germany, and furthermore the involvement of late-presenters into HIV health care.

Item Type:

Journal Article

Creators:

Creators	Email	ORCID	ORCID Put Code
Schleenvoigt, Benjamin Thomas	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Ankert, Juliane	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Stocker, Hartmut	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Stoehr, Albrecht	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Lehmann, Clara	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Schulz, Christian	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Wesselmann, Hans	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Bickel, Markus	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Haberl, Annette	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Degen, Olaf	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Pletz, Mathias Wilhelm	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Seybold, Ulrich	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Stephan, Christoph	UNSPECIFIED	orcid.org/0000-0003-3777-9006	UNSPECIFIED