Sauerbier, Anna, Bachon, Pia, Ambrosio, Leire, Loehrer, Philipp A., Rizos, Alexandra, Jost, Stefanie T., Gronostay, Alexandra, Konitsioti, Agni, Barbe, Michael T. ORCID: 0000-0003-1149-8054, Fink, Gereon R. ORCID: 0000-0002-8230-1856, Ashkan, Keyoumars, Nimsky, Christopher ORCID: 0000-0002-8216-9410, Visser-Vandewalle, Veerle ORCID: 0000-0002-5274-7929, Chaudhuri, K. Ray, Timmermann, Lars ORCID: 0000-0002-5301-3580, Martinez-Martin, Pablo and Dafsari, Haidar S. ORCID: 0000-0001-8849-4233 (2022). The New Satisfaction with Life and Treatment Scale (SLTS-7) in Patients with Parkinson's Disease. J. Parkinsons Dis., 12 (1). S. 453 - 465. AMSTERDAM: IOS PRESS. ISSN 1877-718X

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Abstract

Background: The satisfaction with life and, in particular, with treatment in Parkinson's disease (PD) is understudied. Objective: To explore a new 7-item rating tool assessing satisfaction with life and treatment (SLTS-7) in PD. Methods: In this cross-sectional, multi-center study, including patients screened for advanced therapies, psychometric characteristics of the SLTS-7 were analyzed. An exploratory factor analysis identified the underlying factorial structure of the SLTS-7. Results: 117 patients were included, and the data quality of the SLTS-7 was excellent (computable data 100%), and acceptability measures satisfied standard criteria. Besides the global assessment (item 1), the exploratory factor analysis produced item 2 (physical satisfaction) as an independent item and two factors among the remaining items: items 3-5 (psycho-social satisfaction), and items 6 and 7 (treatment satisfaction). Cronbach's alpha was 0.89, indicative of high internal consistency. The SLTS-7 total score correlated moderately with motor symptoms and weakly with non-motor symptoms total scores. SLTS-7 showed the highest correlations with the European Quality of Life with 5 items (EQ-5D) visual analog scale (0.43-0.58, p <0.01), indicating a moderate convergent validity. The SLTS-7 significantly increased with higher non-motor symptoms burden levels (p = 0.002). Conclusion: Life satisfaction in PD covers three specific aspects, namely physical, psycho-social, and treatment satisfaction. The new SLTS-7 is a valid, reliable, and easy-to-use tool to assess satisfaction with life and treatment in patients with PD screened for advanced therapies. Longitudinal studies analyzing the effect of advanced PD treatment on life and treatment satisfaction are warranted.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Sauerbier, AnnaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bachon, PiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ambrosio, LeireUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Loehrer, Philipp A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rizos, AlexandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jost, Stefanie T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gronostay, AlexandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Konitsioti, AgniUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Barbe, Michael T.UNSPECIFIEDorcid.org/0000-0003-1149-8054UNSPECIFIED
Fink, Gereon R.UNSPECIFIEDorcid.org/0000-0002-8230-1856UNSPECIFIED
Ashkan, KeyoumarsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nimsky, ChristopherUNSPECIFIEDorcid.org/0000-0002-8216-9410UNSPECIFIED
Visser-Vandewalle, VeerleUNSPECIFIEDorcid.org/0000-0002-5274-7929UNSPECIFIED
Chaudhuri, K. RayUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Timmermann, LarsUNSPECIFIEDorcid.org/0000-0002-5301-3580UNSPECIFIED
Martinez-Martin, PabloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dafsari, Haidar S.UNSPECIFIEDorcid.org/0000-0001-8849-4233UNSPECIFIED
URN: urn:nbn:de:hbz:38-692357
DOI: 10.3233/JPD-212823
Journal or Publication Title: J. Parkinsons Dis.
Volume: 12
Number: 1
Page Range: S. 453 - 465
Date: 2022
Publisher: IOS PRESS
Place of Publication: AMSTERDAM
ISSN: 1877-718X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
QUALITY-OF-LIFE; NONMOTOR SYMPTOMS SCALE; DEEP-BRAIN-STIMULATION; VALIDATION; INSTRUMENT; IMPACT; MSIS-29; STN; DBSMultiple languages
NeurosciencesMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/69235

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