Henze, Larissa, Buhl, Christoph, Sandherr, Michael, Cornely, Oliver A. ORCID: 0000-0001-9599-3137, Heinz, Werner J., Khodamoradi, Yascha ORCID: 0000-0001-5972-0967, Kiderlen, Til Ramon, Koehler, Philipp, Seidler, Alrun, Sprute, Rosanne ORCID: 0000-0003-2457-6437, Schmidt-Hieber, Martin and Von Lilienfeld-Toal, Marie (2022). Management of herpesvirus reactivations in patients with solid tumours and hematologic malignancies: update of the Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO) on herpes simplex virus type 1, herpes simplex virus type 2, and varicella zoster virus. Ann. Hematol., 101 (3). S. 491 - 512. NEW YORK: SPRINGER. ISSN 1432-0584

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Abstract

Clinical reactivations of herpes simplex virus or varicella zoster virus occur frequently among patients with malignancies and manifest particularly as herpes simplex stomatitis in patients with acute leukaemia treated with intensive chemotherapy and as herpes zoster in patients with lymphoma or multiple myeloma. In recent years, knowledge on reactivation rates and clinical manifestations has increased for conventional chemotherapeutics as well as for many new antineoplastic agents. This guideline summarizes current evidence on herpesvirus reactivation in patients with solid tumours and hematological malignancies not undergoing allogeneic or autologous hematopoietic stem cell transplantation or other cellular therapy including diagnostic, prophylactic, and therapeutic aspects. Particularly, strategies of risk adapted pharmacological prophylaxis and vaccination are outlined for different patient groups. This guideline updates the guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO) from 2015 Antiviral prophylaxis in patients with solid tumours and haematological malignancies focusing on herpes simplex virus and varicella zoster virus.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Henze, LarissaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buhl, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sandherr, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cornely, Oliver A.UNSPECIFIEDorcid.org/0000-0001-9599-3137UNSPECIFIED
Heinz, Werner J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Khodamoradi, YaschaUNSPECIFIEDorcid.org/0000-0001-5972-0967UNSPECIFIED
Kiderlen, Til RamonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koehler, PhilippUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seidler, AlrunUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sprute, RosanneUNSPECIFIEDorcid.org/0000-0003-2457-6437UNSPECIFIED
Schmidt-Hieber, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Von Lilienfeld-Toal, MarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-693635
DOI: 10.1007/s00277-021-04746-y
Journal or Publication Title: Ann. Hematol.
Volume: 101
Number: 3
Page Range: S. 491 - 512
Date: 2022
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1432-0584
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
LOW-DOSE ACYCLOVIR; CHRONIC LYMPHOCYTIC-LEUKEMIA; STEM-CELL TRANSPLANTATION; RANDOMIZED DOUBLE-BLIND; ACUTE MYELOID-LEUKEMIA; SIMPLEX-VIRUS; MULTIPLE-MYELOMA; VIRAL-INFECTIONS; HODGKIN-LYMPHOMA; ANTIVIRAL PROPHYLAXISMultiple languages
HematologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/69363

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