Universität zu Köln

Catalan, Ana ORCID: 0000-0002-0418-7904, Tognin, Stefania, Kempton, Matthew J., Stahl, Daniel, Salazar de Pablo, Gonzalo ORCID: 0000-0002-6992-0767, Nelson, Barnaby, Pantelis, Christos ORCID: 0000-0002-9565-0238, Riecher-Rossler, Anita, Bressan, Rodrigo, Barrantes-Vidal, Neus, Krebs, Marie-Odile, Nordentoft, Merete, Ruhrmann, Stephan ORCID: 0000-0002-6022-2364, Sachs, Gabriele ORCID: 0000-0002-8359-9877, Rutten, Bart P. F., van Os, Jim, de Haan, Lieuwe, van der Gaag, Mark, Valmaggia, Lucia R. and McGuire, Philip (2022). Relationship between jumping to conclusions and clinical outcomes in people at clinical high-risk for psychosis. Psychol. Med., 52 (8). S. 1569 - 1578. NEW YORK: CAMBRIDGE UNIV PRESS. ISSN 1469-8978

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Abstract

Background Psychosis is associated with a reasoning bias, which manifests as a tendency to 'jump to conclusions'. We examined this bias in people at clinical high-risk for psychosis (CHR) and investigated its relationship with their clinical outcomes. Methods In total, 303 CHR subjects and 57 healthy controls (HC) were included. Both groups were assessed at baseline, and after 1 and 2 years. A 'beads' task was used to assess reasoning bias. Symptoms and level of functioning were assessed using the Comprehensive Assessment of At-Risk Mental States scale (CAARMS) and the Global Assessment of Functioning (GAF), respectively. During follow up, 58 (16.1%) of the CHR group developed psychosis (CHR-T), and 245 did not (CHR-NT). Logistic regressions, multilevel mixed models, and Cox regression were used to analyse the relationship between reasoning bias and transition to psychosis and level of functioning, at each time point. Results There was no association between reasoning bias at baseline and the subsequent onset of psychosis. However, when assessed after the transition to psychosis, CHR-T participants showed a greater tendency to jump to conclusions than CHR-NT and HC participants (55, 17, 17%; chi 2 = 8.13, p = 0.012). There was a significant association between jumping to conclusions (JTC) at baseline and a reduced level of functioning at 2-year follow-up in the CHR group after adjusting for transition, gender, ethnicity, age, and IQ. Conclusions In CHR participants, JTC at baseline was associated with adverse functioning at the follow-up. Interventions designed to improve JTC could be beneficial in the CHR population.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Catalan, Ana UNSPECIFIED orcid.org/0000-0002-0418-7904 UNSPECIFIED Tognin, Stefania UNSPECIFIED UNSPECIFIED UNSPECIFIED Kempton, Matthew J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stahl, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Salazar de Pablo, Gonzalo UNSPECIFIED orcid.org/0000-0002-6992-0767 UNSPECIFIED Nelson, Barnaby UNSPECIFIED UNSPECIFIED UNSPECIFIED Pantelis, Christos UNSPECIFIED orcid.org/0000-0002-9565-0238 UNSPECIFIED Riecher-Rossler, Anita UNSPECIFIED UNSPECIFIED UNSPECIFIED Bressan, Rodrigo UNSPECIFIED UNSPECIFIED UNSPECIFIED Barrantes-Vidal, Neus UNSPECIFIED UNSPECIFIED UNSPECIFIED Krebs, Marie-Odile UNSPECIFIED UNSPECIFIED UNSPECIFIED Nordentoft, Merete UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruhrmann, Stephan UNSPECIFIED orcid.org/0000-0002-6022-2364 UNSPECIFIED Sachs, Gabriele UNSPECIFIED orcid.org/0000-0002-8359-9877 UNSPECIFIED Rutten, Bart P. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED van Os, Jim UNSPECIFIED UNSPECIFIED UNSPECIFIED de Haan, Lieuwe UNSPECIFIED UNSPECIFIED UNSPECIFIED van der Gaag, Mark UNSPECIFIED UNSPECIFIED UNSPECIFIED Valmaggia, Lucia R. UNSPECIFIED UNSPECIFIED UNSPECIFIED McGuire, Philip UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-697305
DOI:	10.1017/S0033291720003396
Journal or Publication Title:	Psychol. Med.
Volume:	52
Number:	8
Page Range:	S. 1569 - 1578
Date:	2022
Publisher:	CAMBRIDGE UNIV PRESS
Place of Publication:	NEW YORK
ISSN:	1469-8978
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language REASONING BIASES; DELUSIONAL CONVICTION; SCHIZOPHRENIA; INDIVIDUALS; SCALE; RELIABILITY; MECHANISMS; SYMPTOMS; VALIDITY Multiple languages Psychology, Clinical; Psychiatry; Psychology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/69730