Debring, Leonie, Happe, Arndt, Fehmer, Vincent and Neugebauer, Joerg (2022). Klinische, kontrollierte, prospektive Kohortenstudie zur Untersuchung der Effektivität einer azellulären dreidimensionalen Kollagenmatrix zur Verdickung der fazialen Mukosa nach Sofortimplantation. PhD thesis, Universität zu Köln.

[img] PDF
Finale Version 0523 .pdf

Download (949kB)


Connective tissue grafts have become a standard for compensating horizontal volume loss in immediate implant placement. The use of new biomaterials like acellular matrices may avoid the need to harvest autogenous grafts, yielding less postoperative morbidity. This randomized comparative study evaluated the clinical outcomes following extraction and immediate implant placement in conjunction with anorganic bovine bone mineral (ABBM) and the use of a porcine acellular dermal matrix (ADM) vs an autogenous connective tissue graft (CTG) in the anterior maxilla. Twenty patients (11 men, 9 women) with a mean age of 48.9 years (range: 21 to 72 years) were included in the study and randomly assigned to either the test (ADM) or control (CTG) group. They underwent tooth extraction and immediate implant placement together with ABBM for socket grafting and either ADM or CTG for soft tissue augmentation. Twelve months after implant placement, the cases were evaluated clinically and volumetrically. All implants achieved osseointegration and were restored. The average horizontal change of the ridge dimension at 1 year postsurgery was –0.55 ± 0.32 mm for the ADM group and –0.60 ± 0.49 mm for the CTG group. Patients of the ADM group reported significantly less postoperative pain. Using xenografts for hard and soft tissue augmentation in conjunction with immediate implant placement showed no difference in the volume change in comparison to an autogenous soft tissue graft, and showed significantly less postoperative morbidity. Int J Periodontics Restorative Dent 2022;42:381–390. doi: 10.11607/prd.5632

Item Type: Thesis (PhD thesis)
CreatorsEmailORCIDORCID Put Code
Debring, Leonieleoniedebring@gmx.deUNSPECIFIEDUNSPECIFIED
Happe, Arndta.happe@dr-happe.deUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-704863
Date: 2022
Language: German
Faculty: Faculty of Medicine
Divisions: Faculty of Medicine > Zahn-, Mund- und Kieferheilkunde
Subjects: Medical sciences Medicine
Uncontrolled Keywords:
Date of oral exam: 8 March 2023
NameAcademic Title
Happe, ArndtPD Dr med.dent
Leschinger, TimPD Dr med
Refereed: Yes


Downloads per month over past year


Actions (login required)

View Item View Item