Universität zu Köln

Journal Article

Auler, Markus, Bergmeier, Vera, Georgieva, Veronika S. ORCID: 0000-0002-9234-2504, Pitzler, Lena, Frie, Christian, Nuechel, Julian, Eckes, Beate, Hinz, Boris and Brachvogel, Bent ORCID: 0000-0002-3923-0554 (2021). miR-127-3p Is an Epigenetic Activator of Myofibroblast Senescence Situated within the MicroRNA-Enriched Dlk1-Dio3-Imprinted Domain on Mouse Chromosome 12. J. Invest. Dermatol., 141 (4). S. 1076 - 1090. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Blumbach, Katrin, Zweers, Manon C., Brunner, Georg, Peters, Andreas S., Schmitz, Markus, Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Schild, Alexander, Denton, Christopher P., Sakai, Takao, Faessler, Reinhard, Krieg, Thomas and Eckes, Beate (2010). Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGF beta 1 levels and RhoA activity. J. Cell Sci., 123 (22). S. 3872 - 3884. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 0021-9533

Eckes, Beate and Eming, Sabine A. (2017). Tissue fibrosis: a pathomechanistically unresolved challenge and scary clinical problem. Exp. Dermatol., 26 (2). S. 135 - 137. HOBOKEN: WILEY. ISSN 1600-0625

Eckes, Beate, Krieg, Thomas and Wickstroem, Sara A. (2014). Role of integrin signalling through integrin-linked kinase in skin physiology and pathology. Exp. Dermatol., 23 (7). S. 453 - 457. HOBOKEN: WILEY. ISSN 1600-0625

Eckes, Beate, Moinzadeh, Pia, Sengle, Gerhard, Hunzelmann, Nico and Krieg, Thomas (2014). Molecular and cellular basis of scleroderma. J. Mol. Med., 92 (9). S. 913 - 925. NEW YORK: SPRINGER. ISSN 1432-1440

Eckes, Beate, Wang, Fang, Moinzadeh, Pia, Hunzelmann, Nicolas and Krieg, Thomas (2017). Pathophysiological Mechanisms in Sclerosing Skin Diseases. Front. Med., 4. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-858X

Eckes, Beate ORCID: 0000-0002-0936-0702, Wang, Fang, Moinzadeh, Pia, Hunzelmann, Nicolas and Krieg, Thomas M. ORCID: 0000-0001-5616-8476 (2017). Pathophysiological Mechanisms in Sclerosing Skin Diseases. Frontiers in Medicine, 4. Frontiers Media. ISSN 2296-858X

Etich, Julia ORCID: 0000-0003-3238-6692, Rehberg, Mirko, Eckes, Beate, Sengle, Gerhard, Semler, Oliver and Zaucke, Frank ORCID: 0000-0002-7680-9354 (2020). Signaling pathways affected by mutations causing osteogenesis imperfecta. Cell. Signal., 76. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1873-3913

Fleger-Weckmann, Anja, Uestuen, Yasemin, Kloepper, Jennifer, Paus, Ralf, Bloch, Wilhelm, Chen, Zu-Lin, Wegner, Jeannine, Sorokin, Lydia, Langbein, Lutz, Eckes, Beate, Zigrino, Paola ORCID: 0000-0002-7470-0064, Krieg, Thomas and Nischt, Roswitha (2016). Deletion of the epidermis derived laminin gamma 1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol., 56. S. 42 - 57. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802

Fleger-Weckmann, Anja, Üstün, Yasemin ORCID: 0000-0002-2612-5720, Kloepper, Jennifer, Paus, Ralf ORCID: 0000-0002-3492-9358, Bloch, Wilhelm, Chen, Zu-Lin, Wegner, Jeannine, Sorokin, Lydia, Langbein, Lutz, Eckes, Beate ORCID: 0000-0002-0936-0702, Zigrino, Paola ORCID: 0000-0002-7470-0064, Krieg, Thomas M. ORCID: 0000-0001-5616-8476 and Nischt, Roswitha (2016). Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biology, 56. pp. 42-56. Elsevier. ISSN 0945-053X

Ghatak, Sushmita, Niland, Stephan, Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Wang, Fang, Eble, Johannes A., Leitges, Michael, Mauch, Cornelia, Krieg, Thomas, Zigrino, Paola ORCID: 0000-0002-7470-0064 and Eckes, Beate (2016). Role of Integrins alpha 1 beta 1 and alpha 2 beta 1 in Wound and Tumor Angiogenesis in Mice. Am. J. Pathol., 186 (11). S. 3011 - 3028. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1525-2191

Ghatak, Sushmita, Niland, Stephan, Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Wang, Fang, Eble, Johannes A. ORCID: 0000-0001-9156-2137, Leitges, Michael ORCID: 0000-0003-4203-6995, Mauch, Cornelia ORCID: 0000-0002-3989-0536, Krieg, Thomas M. ORCID: 0000-0001-5616-8476, Zigrino, Paola ORCID: 0000-0002-7470-0064 and Eckes, Beate ORCID: 0000-0002-0936-0702 (2016). Role of Integrins α1β1 and α2β1 in Wound and Tumor Angiogenesis in Mice. The American Journal of Pathology, 186 (11). pp. 3011-3027. Elsevier. ISSN 0002-9440

Jungmann, Oliver, Nikolovska, Katerina, Stock, Christian, Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Eckes, Beate, Riethmueller, Christoph, Owens, Rick T., Iozzo, Renato V. and Seidler, Daniela G. (2012). ` The Dermatan Sulfate Proteoglycan Decorin Modulates alpha 2 beta 1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis. PLoS One, 7 (12). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Kronenberg, Daniel ORCID: 0000-0001-6807-7328, Michel, Philipp A., Hochstrat, Eva, Wei, Ma, Brinckmann, Juergen, Mueller, Marcus, Frank, Andre ORCID: 0000-0001-7099-9719, Hansen, Uwe, Eckes, Beate and Stange, Richard ORCID: 0000-0003-0807-3151 (2020). Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin alpha 2 beta 1-Deficient Mice. Int. J. Mol. Sci., 21 (8). BASEL: MDPI. ISSN 1422-0067

Lettmann, Sandra, Bloch, Wilhelm, Maass, Tobias, Niehoff, Anja ORCID: 0000-0002-4165-0929, Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Eckes, Beate, Eming, Sabine A., Bonaldo, Paolo, Paulsson, Mats and Wagener, Raimund (2014). Col6a1 Null Mice as a Model to Study Skin Phenotypes in Patients with Collagen VI Related Myopathies: Expression of Classical and Novel Collagen VI Variants during Wound Healing. PLoS One, 9 (8). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Liu, Shangxi, Blumbach, Katrin, Eastwood, Mark, Denton, Christopher P., Eckes, Beate, Krieg, Thomas, Abraham, David J. and Leask, Andrew (2010). Expression of integrin beta 1 by fibroblasts is required for tissue repair in vivo. J. Cell Sci., 123 (21). S. 3674 - 3683. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 1477-9137

Nuechel, Julian, Ghatak, Sushmita, Zuk, Alexandra V., Illerhaus, Anja, Morgelin, Matthias, Schoenborn, Katrin, Blumbach, Katrin, Wickstroem, Sara A., Krieg, Thomas, Sengle, Gerhard, Plomann, Markus and Eckes, Beate (2018). TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy, 14 (3). S. 465 - 487. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1554-8635

Nuechel, Julian, Tauber, Marina, Nolte, Janica L., Moergelin, Matthias, Tuerk, Clara, Eckes, Beate, Demetriades, Constantinos ORCID: 0000-0001-7813-7726 and Plomann, Markus (2021). An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress. Mol. Cell, 81 (16). S. 3275 - 3307. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Peters, Andreas S., Brunner, Georg, Blumbach, Katrin, Abraham, David J., Krieg, Thomas and Eckes, Beate (2012). Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGF beta 1 in dermal fibroblasts. Exp. Dermatol., 21 (10). S. 765 - 771. HOBOKEN: WILEY. ISSN 1600-0625

Peters, Andreas S., Brunner, Georg, Krieg, Thomas and Eckes, Beate (2015). Cyclic mechanical strain induces TGF beta 1-signalling in dermal fibroblasts embedded in a 3D collagen lattice. Arch. Dermatol. Res., 307 (2). S. 191 - 198. NEW YORK: SPRINGER. ISSN 1432-069X

Peters, Andreas S., Brunner, Georg, Krieg, Thomas and Eckes, Beate (2015). Cyclic mechanical strain induces TGF beta 1-signalling in dermal fibroblasts embedded in a 3D collagen lattice. Arch. Dermatol. Res., 307 (2). S. 191 - 198. NEW YORK: SPRINGER. ISSN 1432-069X

Peters, Andreas S. ORCID: 0000-0002-1347-7575, Brunner, Georg, Krieg, Thomas M. ORCID: 0000-0001-5616-8476 and Eckes, Beate ORCID: 0000-0002-0936-0702 (2015). Cyclic mechanical strain induces TGFβ1-signalling in dermal fibroblasts embedded in a 3D collagen lattice. Archives of Dermatological Research, 307 (2). pp. 191-197. Springer. ISSN 0340-3696

Rubel, Diana, Frese, Jenny, Martin, Maria, Leibnitz, Alexander, Girgert, Rainer ORCID: 0000-0001-8210-242X, Miosge, Nicolai, Eckes, Beate, Mueller, Gerhard-Anton and Gross, Oliver (2014). Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2betal delays kidney fibrosis in COL4A3 knockout mice. Matrix Biol., 34. S. 13 - 22. AMSTERDAM: ELSEVIER. ISSN 1569-1802

Sawant, Mugdha, Hinz, Boris, Schonborn, Katrin, Zeinert, Isabel, Eckes, Beate, Krieg, Thomas and Schuster, Ronen ORCID: 0000-0002-8640-4692 (2021). A story of fibers and stress: Matrix-embedded signals for fibroblast activation in the skin. Wound Repair Regen., 29 (4). S. 515 - 531. HOBOKEN: WILEY. ISSN 1524-475X

Sawant, Mugdha ORCID: 0000-0002-0329-2868, Hinz, Boris ORCID: 0000-0002-0526-393X, Schönborn, Katrin, Zeinert, Isabel ORCID: 0000-0001-5790-7306, Eckes, Beate ORCID: 0000-0002-0936-0702, Krieg, Thomas M. ORCID: 0000-0001-5616-8476 and Schuster, Ronen ORCID: 0000-0002-8640-4692 (2021). A story of fibers and stress: Matrix‐embedded signals for fibroblast activation in the skin. Wound Repair and Regeneration, Special Issue on Myofibroblasts, 29 (4). pp. 515-530. Wiley. ISSN 1067-1927

Schiller, Herbert B., Mayr, Christoph H., Leuschner, Gabriela, Strunz, Maximilian, Staab-Weijnitz, Claudia, Preisendoerfer, Stefan, Eckes, Beate, Moinzadeh, Pia, Krieg, Thomas, Schwartz, David A., Hatz, Rudolf A., Behr, Juergen, Mann, Matthias and Eickelberg, Oliver (2017). Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis. Am. J. Respir. Crit. Care Med., 196 (10). S. 1298 - 1311. NEW YORK: AMER THORACIC SOC. ISSN 1535-4970

Schiller, Herbert B. ORCID: 0000-0001-9498-7034, Mayr, Christoph H. ORCID: 0000-0001-5353-4768, Leuschner, Gabriela, Strunz, Maximilian, Staab-Weijnitz, Claudia ORCID: 0000-0002-1211-7834, Preisendörfer, Stefan ORCID: 0000-0003-2320-5175, Eckes, Beate ORCID: 0000-0002-0936-0702, Moinzadeh, Pia ORCID: 0000-0002-8784-8615, Krieg, Thomas M. ORCID: 0000-0001-5616-8476, Schwartz, David A., Hatz, Rudolf A., Behr, Jürgen, Mann, Matthias and Eickelberg, Oliver ORCID: 0000-0001-7170-0360 (2017). Deep Proteome Profiling Reveals Common Prevalence of MZB1-Positive Plasma B Cells in Human Lung and Skin Fibrosis. American Journal of Respiratory and Critical Care Medicine, 196 (10). pp. 1298-1310. American Thoracic Society. ISSN 1073-449X

Schmidt, Manuela, Gutknecht, Danny, Anastassiadis, Konstantinos ORCID: 0000-0002-9814-0559, Eckes, Beate, Anderegg, Ulf and Saalbach, Anja (2016). Thy-1/beta 3 Integrin Interaction-Induced Apoptosis of Dermal Fibroblasts Is Mediated by Up-Regulation of FasL Expression. J. Invest. Dermatol., 136 (2). S. 526 - 530. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Schmidt, Manuela, Gutknecht, Danny, Simon, Jan C., Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Eckes, Beate, Anderegg, Ulf and Saalbach, Anja (2015). Controlling the Balance of Fibroblast Proliferation and Differentiation: Impact of Thy-1. J. Invest. Dermatol., 135 (7). S. 1893 - 1903. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1523-1747

Schonboern, Katrin, Willenborg, Sebastian, Schulz, Jan-Niklas, Imhof, Thomas, Eming, Sabine A., Quondamatteo, Fabio, Brinckmann, Juergen, Niehoff, Anja ORCID: 0000-0002-4165-0929, Paulsson, Mats, Koch, Manuel, Eckes, Beate and Krieg, Thomas (2020). Role of collagen XII in skin homeostasis and repair. Matrix Biol., 94. S. 57 - 77. AMSTERDAM: ELSEVIER. ISSN 1569-1802

Schulz, Jan-Nikias, Plomann, Markus, Sengle, Gerhard, Gullberg, Donald ORCID: 0000-0002-7245-4437, Krieg, Thomas and Eckes, Beate (2018). New developments on skin fibrosis - Essential signals emanating from the extracellular matrix for the control of myofibroblasts. Matrix Biol., 68-69. S. 522 - 533. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802

Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Nuechel, Julian, Niehoff, Anja, Bloch, Wilhelm, Schoenborn, Katrin, Hayashi, Shujiro, Kamper, Matthias, Brinckmann, Juergen, Plomann, Markus, Paulsson, Mats, Krieg, Thomas, Zaucke, Frank and Eckes, Beate (2016). COMP-assisted collagen secretion - a novel intracellular function required for fibrosis. J. Cell Sci., 129 (4). S. 706 - 717. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 1477-9137

Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Nüchel, Julian Maria ORCID: 0000-0002-8126-415X, Niehoff, Anja ORCID: 0000-0002-4165-0929, Bloch, Wilhelm ORCID: 0000-0003-1786-8853, Schönborn, Katrin, Hayashi, Shujiro ORCID: 0000-0001-6558-4818, Kamper, Matthias, Brinckmann, Jürgen, Plomann, Markus ORCID: 0000-0001-6509-5627, Paulsson, Mats ORCID: 0000-0002-6846-857X, Krieg, Thomas M. ORCID: 0000-0001-5616-8476, Zaucke, Frank ORCID: 0000-0002-7680-9354 and Eckes, Beate ORCID: 0000-0002-0936-0702 (2016). COMP-assisted collagen secretion - a novel intracellular function required for fibrosis. Journal of Cell Science, 129. pp. 706-716. Company of Biologists Limited. ISSN 0021-9533

Schönborn, Katrin, Willenborg, Sebastian ORCID: 0000-0002-0840-227X, Schulz, Jan-Niklas ORCID: 0000-0001-9286-206X, Imhof, Thomas ORCID: 0000-0002-0554-7617, Eming, Sabine A., Quondamatteo, Fabio ORCID: 0000-0001-6208-3436, Brinckmann, Jürgen, Niehoff, Anja ORCID: 0000-0002-4165-0929, Paulsson, Mats ORCID: 0000-0002-6846-857X, Koch, Manuel ORCID: 0000-0002-2962-7814, Eckes, Beate ORCID: 0000-0002-0936-0702 and Krieg, Thomas M. ORCID: 0000-0001-5616-8476 (2020). Role of collagen XII in skin homeostasis and repair. Matrix Biology, 94. pp. 57-76. Elsevier. ISSN 0945-053X

Semeniak, Daniela, Kulawig, Rebecca, Stegner, David ORCID: 0000-0003-1059-9865, Meyer, Imke, Schwiebert, Silke, Boesing, Hendrik, Eckes, Beate, Nieswandt, Bernhard and Schulze, Harald ORCID: 0000-0003-1285-6407 (2016). Proplatelet formation is selectively inhibited by collagen type I through Syk-independent GPVI signaling. J. Cell Sci., 129 (18). S. 3473 - 3485. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 1477-9137

Uestuen, Yasemin, Reibetanz, Marion, Brachvogel, Bent, Nischt, Roswitha, Eckes, Beate, Zigrino, Paola ORCID: 0000-0002-7470-0064 and Krieg, Thomas (2019). Dual role of laminin-511 in regulating melanocyte migration and differentiation. Matrix Biol., 80. S. 59 - 72. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802

Wegner, Jeannine, Loser, Karin, Apsite, Gunita, Nischt, Roswitha, Eckes, Beate, Krieg, Thomas, Werner, Sabine and Sorokin, Lydia (2016). Laminin alpha 5 in the keratinocyte basement membrane is required for epidermal-dermal intercommunication. Matrix Biol., 56. S. 24 - 42. AMSTERDAM: ELSEVIER. ISSN 1569-1802

Wegner, Jeannine, Loser, Karin ORCID: 0000-0002-0007-0936, Apsite, Gunita ORCID: 0000-0002-2908-8398, Nischt, Roswitha, Eckes, Beate ORCID: 0000-0002-0936-0702, Krieg, Thomas M. ORCID: 0000-0001-5616-8476, Werner, Sabine ORCID: 0000-0001-7397-8710 and Sorokin, Lydia ORCID: 0000-0001-7704-7921 (2016). Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication. Matrix Biology, 56. pp. 24-41. Elsevier. ISSN 0945-053X

Willenborg, Sebastian, Eckes, Beate, Brinckmann, Juergen, Krieg, Thomas, Waisman, Ari ORCID: 0000-0003-4304-8234, Hartmann, Karin ORCID: 0000-0002-4595-8226, Roers, Axel and Eming, Sabine A. (2014). Genetic Ablation of Mast Cells Redefines the Role of Mast Cells in Skin Wound Healing and Bleomycin-Induced Fibrosis. J. Invest. Dermatol., 134 (7). S. 2005 - 2016. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Willenborg, Sebastian, Eckes, Beate, Juengst, Christian, Sengle, Gerhard, Zaucke, Frank ORCID: 0000-0002-7680-9354 and Eming, Sabine A. (2018). Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program. J. Immunol., 201 (2). S. 663 - 675. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Zehender, Ariella, Li, Yi-Nan, Lin, Neng-Yu, Stefanica, Adrian, Nuechel, Julian, Chen, Chih-Wei, Hsu, Hsiao-Han, Zhu, Honglin, Ding, Xiao, Huang, Jingang, Shen, Lichong, Gyoerfi, Andrea-Hermina, Soare, Alina, Rauber, Simon, Bergmann, Christina, Ramming, Andreas, Plomann, Markus, Eckes, Beate, Schett, Georg and Distler, Joerg H. W. (2021). TGF beta promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy. Nat. Commun., 12 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723

Zigrino, Paola ORCID: 0000-0002-7470-0064, Brinckmann, Juergen, Niehoff, Anja, Lu, Yinhui, Giebeler, Nives, Eckes, Beate, Kadler, Karl E. and Mauch, Cornelia (2016). Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin. J. Invest. Dermatol., 136 (8). S. 1575 - 1584. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Üstün, Yasemin ORCID: 0000-0002-2612-5720, Reibetanz, Marion, Brachvogel, Bent ORCID: 0000-0002-3923-0554, Nischt, Roswitha, Eckes, Beate ORCID: 0000-0002-0936-0702, Zigrino, Paola ORCID: 0000-0002-7470-0064 and Krieg, Thomas ORCID: 0000-0001-5616-8476 (2019). Dual role of laminin‑511 in regulating melanocyte migration and differentiation. Matrix Biology, 80. pp. 59-71. Elsevier. ISSN 0945-053X