Universität zu Köln

Journal Article

Doering, Matthias, Kreer, Christoph ORCID: 0000-0002-9140-9850, Lehnen, Nathalie, Klein, Florian and Pfeifer, Nico (2019). Modeling the Amplification of Immunoglobulins through Machine Learning on Sequence-Specific Features. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Ehrhardt, Stefanie A., Zehner, Matthias, Kraehling, Verena, Cohen-Dvashi, Hadas, Kreer, Christoph ORCID: 0000-0002-9140-9850, Elad, Nadav ORCID: 0000-0001-6222-2280, Gruell, Henning, Ercanoglu, Meryem S., Schommers, Philipp ORCID: 0000-0003-3375-6800, Gieselmann, Lutz, Eggeling, Ralf ORCID: 0000-0002-3583-1029, Dahlke, Christine, Wolf, Timo, Pfeifer, Nico, Addo, Marylyn M., Diskin, Ron, Becker, Stephan and Klein, Florian (2019). Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV. Nat. Med., 25 (10). S. 1589 - 1614. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-170X

Ercanoglu, Meryem Seda, Gieselmann, Lutz ORCID: 0000-0003-3699-3318, Daehling, Sabrina, Poopalasingam, Nareshkumar ORCID: 0000-0002-4981-6209, Detmer, Susanne, Koch, Manuel ORCID: 0000-0002-2962-7814, Korenkov, Michael ORCID: 0000-0002-2988-8483, Halwe, Sandro, Kluever, Michael, Di Cristanziano, Veronica, Janicki, Hanna, Schlotz, Maike, Worczinski, Johanna, Gathof, Birgit, Gruell, Henning, Zehner, Matthias ORCID: 0000-0001-5745-0836, Becker, Stephan, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Kreer, Christoph ORCID: 0000-0002-9140-9850 and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults. iScience, 25 (3). CAMBRIDGE: CELL PRESS. ISSN 2589-0042

Gieselmann, Lutz, Kreer, Christoph ORCID: 0000-0002-9140-9850, Ercanoglu, Meryem Seda, Lehnen, Nathalie, Zehner, Matthias, Schommers, Philipp ORCID: 0000-0003-3375-6800, Potthoff, Julian, Gruell, Henning and Klein, Florian (2021). Effective high-throughput isolation of fully human antibodies targeting infectious pathogens. Nat. Protoc., 16 (7). S. 3639 - 3672. BERLIN: NATURE PORTFOLIO. ISSN 1750-2799

Gruell, Henning, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Korenkov, Michael, Tober-Lau, Pinkus, Zehner, Matthias, Munn, Friederike, Janicki, Hanna, Augustin, Max, Schommers, Philipp, Sander, Leif Erik, Kurth, Florian ORCID: 0000-0002-3807-473X, Kreer, Christoph and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns. Cell Host Microbe, 30 (9). S. 1231 - 1249. CAMBRIDGE: CELL PRESS. ISSN 1934-6069

Gruell, Henning, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Weber, Timm, Barnes, Christopher O., Kreer, Christoph and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). Antibody-mediated neutralization of SARS-CoV-2. Immunity, 55 (6). S. 925 - 945. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Halwe, Sandro ORCID: 0000-0002-4021-7728, Kupke, Alexandra ORCID: 0000-0001-8517-4779, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Liberta, Falk, Gruell, Henning, Zehner, Matthias, Rohde, Cornelius ORCID: 0000-0002-4752-8326, Kraehling, Verena, Gellhorn Serra, Michelle ORCID: 0000-0002-0322-3555, Kreer, Christoph ORCID: 0000-0002-9140-9850, Kluever, Michael, Sauerhering, Lucie, Schmidt, Jorg, Cai, Zheng, Han, Fei, Young, David, Yang, Guangwei, Widera, Marek ORCID: 0000-0001-5417-9307, Koch, Manuel ORCID: 0000-0002-2962-7814, Werner, Anke, Kaemper, Lennart, Becker, Nico, Marlow, Michael S., Eickmann, Markus, Ciesek, Sandra ORCID: 0000-0002-1802-7565, Schiele, Felix, Klein, Florian and Becker, Stephan (2021). Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. Viruses-Basel, 13 (8). BASEL: MDPI. ISSN 1999-4915

Kreer, Christoph, Doering, Matthias, Lehnen, Nathalie, Ercanoglu, Meryem S., Gieselmann, Lutz, Luca, Domnica, Jain, Kanika, Schommers, Philipp, Pfeifer, Nico and Klein, Florian (2020). openPrimeR for multiplex ampli fi cation of highly diverse templates. J. Immunol. Methods, 480. AMSTERDAM: ELSEVIER. ISSN 1872-7905

Kreer, Christoph ORCID: 0000-0002-9140-9850, Gruell, Henning, Mora, Thierry, Walczak, Aleksandra M. and Klein, Florian (2020). Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies. Vaccines, 8 (1). BASEL: MDPI. ISSN 2076-393X

Kreer, Christoph, Zehner, Matthias, Weber, Timm, Ercanoglu, Meryem S., Gieselmann, Lutz, Rohde, Cornelius, Halwe, Sandro, Korenkov, Michael, Schommers, Philipp ORCID: 0000-0003-3375-6800, Vanshylla, Kanika, Di Cristanziano, Veronica, Janicki, Hanna, Brinker, Reinhild, Ashurov, Artem, Kraehling, Verena, Kupke, Alexandra, Cohen-Dvashi, Hadas, Koch, Manuel, Eckert, Jan Mathis, Lederer, Simone, Pfeifer, Nico, Wolf, Timo, Vehreschild, Maria J. G. T., Wendtner, Clemens, Diskin, Ron, Gruell, Henning, Becker, Stephan and Klein, Florian (2020). Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients. Cell, 182 (4). S. 843 - 867. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Schommers, Philipp ORCID: 0000-0003-3375-6800, Gruell, Henning, Abernathy, Morgan E., Tran, My-Kim, Dingens, Adam S., Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika, Kreer, Christoph, Weiland, Daniela, Holtick, Udo, Scheid, Christof, Valter, Markus M., van Gils, Marit J. ORCID: 0000-0003-3422-8161, Sanders, Rogier W., Vehreschild, Joerg J., Cornely, Oliver A., Lehmann, Clara, Faetkenheuer, Gerd, Seaman, Michael S., Bloom, Jesse D., Bjorkman, Pamela J. and Klein, Florian (2020). Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180 (3). S. 471 - 512. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Schommers, Philipp Frederik ORCID: 0000-0003-3375-6800, Gruell, Henning ORCID: 0000-0002-0725-7138, Abernathy, Morgan E. ORCID: 0000-0001-9959-7713, Tran, My-Kim, Dingens, Adam S. ORCID: 0000-0001-9603-9409, Gristick, Harry B., Barnes, Christopher O., Schoofs, Till, Schlotz, Maike, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Kreer, Christoph ORCID: 0000-0002-9140-9850, Weiland, Daniela, Holtick, Udo ORCID: 0000-0002-5543-0257, Scheid, Christof ORCID: 0009-0007-6539-226X, Valter, Markus M., van Gils, Marit J. ORCID: 0000-0003-3422-8161, Sanders, Rogier W., Vehreschild, Jörg J. ORCID: 0000-0002-5446-7170, Cornely, Oliver A. ORCID: 0000-0001-9599-3137, Lehmann, Clara ORCID: 0000-0002-7042-1578, Fätkenheuer, Gerd ORCID: 0000-0002-5054-1871, Seaman, Michael S. ORCID: 0000-0001-6444-3562, Bloom, Jesse D., Bjorkman, Pamela J. ORCID: 0000-0002-2277-3990 and Klein, Florian ORCID: 0000-0003-1376-1792 (2020). Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Cell, 180 (3). 471-489.e22. Cell Press. ISSN 0092-8674

Theobald, Sebastian ORCID: 0000-0001-7042-8326, Simonis, Alexander ORCID: 0000-0003-2945-9897, Georgomanolis, Theodoros ORCID: 0000-0002-4066-9257, Kreer, Christoph ORCID: 0000-0002-9140-9850, Zehner, Matthias ORCID: 0000-0001-5745-0836, Eisfeld, Hannah S, Albert, Marie‐Christine, Chhen, Jason, Motameny, Susanne ORCID: 0000-0003-1186-1108, Erger, Florian ORCID: 0000-0002-2768-1702, Fischer, Julia ORCID: 0000-0001-6138-7454, Malin, Jakob J ORCID: 0000-0002-2989-0436, Gräb, Jessica, Winter, Sandra ORCID: 0000-0002-4930-2005, Pouikli, Andromachi ORCID: 0000-0003-1868-6875, David, Friederike ORCID: 0000-0001-9521-5669, Böll, Boris ORCID: 0000-0002-6432-0981, Koehler, Philipp ORCID: 0000-0002-7386-7495, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Gruell, Henning ORCID: 0000-0002-0725-7138, Suarez, Isabelle ORCID: 0000-0002-9863-9675, Hallek, Michael ORCID: 0000-0002-7425-4455, Fätkenheuer, Gerd ORCID: 0000-0002-5054-1871, Jung, Norma ORCID: 0000-0002-5740-0772, Cornely, Oliver A. ORCID: 0000-0001-9599-3137, Lehmann, Clara ORCID: 0000-0002-7042-1578, Tessarz, Peter ORCID: 0000-0002-6953-9835, Altmüller, Janine, Nürnberg, Peter ORCID: 0000-0002-7228-428X, Kashkar, Hamid ORCID: 0000-0003-2796-1429, Klein, Florian ORCID: 0000-0003-1376-1792, Koch, Manuel ORCID: 0000-0002-2962-7814 and Rybniker, Jan ORCID: 0000-0001-8351-2690 (2021). Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19. EMBO Molecular Medicine, 13 (8). e14150. Wiley. ISSN 1757-4676

Theobald, Sebastian J., Kreer, Christoph, Khailaie, Sahamoddin, Bonifacius, Agnes ORCID: 0000-0002-0112-967X, Eiz-Vesper, Britta, Figueiredo, Constanca, Mach, Michael, Backovic, Marija ORCID: 0000-0001-8814-4428, Ballmaier, Matthias ORCID: 0000-0002-1352-5995, Koenig, Johannes, Olbrich, Henning, Schneider, Andreas, Volk, Valery, Danisch, Simon, Gieselmann, Lutz, Ercanoglu, Meryem Seda, Messerle, Martin, von Kaisenberg, Constantin, Witte, Torsten, Klawonn, Frank, Meyer-Hermann, Michael, Klein, Florian and Stripecke, Renata (2020). Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. PLoS Pathog., 16 (7). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1553-7374

Theobald, Sebastian J., Simonis, Alexander ORCID: 0000-0003-2945-9897, Georgomanolis, Theodoros ORCID: 0000-0002-4066-9257, Kreer, Christoph ORCID: 0000-0002-9140-9850, Zehner, Matthias, Eisfeld, Hannah S., Albert, Marie-Christine, Chhen, Jason, Motameny, Susanne, Erger, Florian ORCID: 0000-0002-2768-1702, Fischer, Julia ORCID: 0000-0001-6138-7454, Malin, Jakob J. ORCID: 0000-0002-2989-0436, Graeb, Jessica, Winter, Sandra, Pouikli, Andromachi ORCID: 0000-0003-1868-6875, David, Friederike ORCID: 0000-0001-9521-5669, Boell, Boris, Koehler, Philipp ORCID: 0000-0002-7386-7495, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Gruell, Henning, Suarez, Isabelle, Hallek, Michael, Faetkenheuer, Gerd, Jung, Norma, Cornely, Oliver A., Lehmann, Clara, Tessarz, Peter ORCID: 0000-0002-6953-9835, Altmueller, Janine, Nuernberg, Peter, Kashkar, Hamid, Klein, Florian, Koch, Manuel ORCID: 0000-0002-2962-7814 and Rybniker, Jan (2021). Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19. EMBO Mol. Med., 13 (8). HOBOKEN: WILEY. ISSN 1757-4684

Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Fan, Chengcheng ORCID: 0000-0003-4213-5758, Wunsch, Marie ORCID: 0000-0002-6570-1831, Poopalasingam, Nareshkumar ORCID: 0000-0002-4981-6209, Meijers, Matthijs ORCID: 0000-0002-1876-8064, Kreer, Christoph ORCID: 0000-0002-9140-9850, Kleipass, Franziska ORCID: 0009-0003-7120-6620, Ruchnewitz, Denis ORCID: 0000-0001-5740-6958, Ercanoglu, Meryem S., Gruell, Henning, Muenn, Friederike, Pohl, Kai, Janicki, Hanna, Nolden, Tobias ORCID: 0000-0002-8996-5612, Bartl, Simone, Stein, Saskia C., Augustin, Max, Dewald, Felix, Gieselmann, Lutz, Schommers, Philipp, Schulz, Thomas F., Sander, Leif Erik, Koch, Manuel ORCID: 0000-0002-2962-7814, Luksza, Marta, Laessig, Michael, Bjorkman, Pamela J. and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers. Cell Host Microbe, 30 (1). S. 69 - 94. CAMBRIDGE: CELL PRESS. ISSN 1934-6069

Weber, Timm ORCID: 0000-0003-2079-842X, Potthoff, Julian, Bizu, Sven ORCID: 0000-0003-4839-2472, Labuhn, Maurice, Dold, Leona, Schoofs, Till, Horning, Marcel ORCID: 0000-0003-1468-4645, Ercanoglu, Meryem S., Kreer, Christoph ORCID: 0000-0002-9140-9850, Gieselmann, Lutz ORCID: 0000-0003-3699-3318, Vanshylla, Kanika ORCID: 0000-0003-4552-9170, Langhans, Bettina, Janicki, Hanna, Stroeh, Luisa J., Knops, Elena, Nierhoff, Dirk, Spengler, Ulrich, Kaiser, Rolf, Bjorkman, Pamela J., Krey, Thomas, Bankwitz, Dorothea, Pfeifer, Nico ORCID: 0000-0002-4647-8566, Pietschmann, Thomas, Flyak, Andrew, I and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Immunity, 55 (2). S. 341 - 363. CAMBRIDGE: CELL PRESS. ISSN 1097-4180