Universität zu Köln

Telishevska, Marta, Hebe, J., Paul, T., Nuernberg, J. H., Krause, U., Gebauer, R., Gass, M., Balmer, C., Berger, F., Molatta, S., Emmel, M., Lawrenz, W., Kriebel, T. and Hessling, G. (2019). Catheter ablation in ASymptomatic PEDiatric patients with ventricular preexcitation: results from the multicenter CASPED study. Clin. Res. Cardiol., 108 (6). S. 683 - 691. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1861-0692

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Abstract

BackgroundAs there are limited data about the clinical practice of catheter ablation in asymptomatic children and adolescents with ventricular preexcitation on ECG, we performed the multicenter CASPED (Catheter ablation in ASymptomatic PEDiatric patients with Ventricular Preexcitation) study.Methods and resultsIn 182 consecutive children and adolescents aged between 8 and 18years (mean age 12.92.6years; 65% male) with asymptomatic ventricular preexcitation, a total of 196 accessory pathways (APs) were targeted. APs were right sided (62%) or left sided (38%). The most common right-sided AP location was the posteroseptal region (38%). Ablation was performed using radiofrequency (RF) energy (93%), cryoablation (4%) or both (3%). Mean procedure time was 137.6 +/- 62.0min with a mean fluoroscopy time of 15.6 +/- 13.8min. A 3D mapping or catheter localization system was used in 32% of patients. Catheter ablation was acutely successful in 166/182 patients (91.2%). Mortality was 0% and there were no major periprocedural complications. AP recurrence was observed in 14/166 patients (8.4%) during a mean follow-up time of 19.7 +/- 8.5months. A second ablation attempt was performed in 20 patients and was successful in 16/20 patients (80%). Overall, long-term success rate was 92.3%.Conclusion p id=Par3 In this retrospective multicenter study, the outcome of catheter ablation for asymptomatic preexcitation in children and adolescents irrespective of antegrade AP conduction properties is summarized. The complication rate was low and success rate was high, the latter mainly depending on pathway location. The promising results of the study may have future impact on the ongoing risk-benefit discussion regarding catheter ablation in the setting of asymptomatic preexcitation in children and adolescents.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Telishevska, Marta UNSPECIFIED UNSPECIFIED UNSPECIFIED Hebe, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Paul, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Nuernberg, J. H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Krause, U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gebauer, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gass, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Balmer, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Berger, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Molatta, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Emmel, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lawrenz, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kriebel, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hessling, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-147145
DOI:	10.1007/s00392-018-1397-x
Journal or Publication Title:	Clin. Res. Cardiol.
Volume:	108
Number:	6
Page Range:	S. 683 - 691
Date:	2019
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1861-0692
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language WOLFF-PARKINSON-WHITE; EXPERT CONSENSUS STATEMENT; RADIOFREQUENCY ABLATION; CARDIAC ABLATION; CHILDREN; RISK; RECURRENCE; WPW Multiple languages Cardiac & Cardiovascular Systems Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14714