Telishevska, Marta, Hebe, J., Paul, T., Nuernberg, J. H., Krause, U., Gebauer, R., Gass, M., Balmer, C., Berger, F., Molatta, S., Emmel, M., Lawrenz, W., Kriebel, T. and Hessling, G. (2019). Catheter ablation in ASymptomatic PEDiatric patients with ventricular preexcitation: results from the multicenter CASPED study. Clin. Res. Cardiol., 108 (6). S. 683 - 691. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1861-0692

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Abstract

BackgroundAs there are limited data about the clinical practice of catheter ablation in asymptomatic children and adolescents with ventricular preexcitation on ECG, we performed the multicenter CASPED (Catheter ablation in ASymptomatic PEDiatric patients with Ventricular Preexcitation) study.Methods and resultsIn 182 consecutive children and adolescents aged between 8 and 18years (mean age 12.92.6years; 65% male) with asymptomatic ventricular preexcitation, a total of 196 accessory pathways (APs) were targeted. APs were right sided (62%) or left sided (38%). The most common right-sided AP location was the posteroseptal region (38%). Ablation was performed using radiofrequency (RF) energy (93%), cryoablation (4%) or both (3%). Mean procedure time was 137.6 +/- 62.0min with a mean fluoroscopy time of 15.6 +/- 13.8min. A 3D mapping or catheter localization system was used in 32% of patients. Catheter ablation was acutely successful in 166/182 patients (91.2%). Mortality was 0% and there were no major periprocedural complications. AP recurrence was observed in 14/166 patients (8.4%) during a mean follow-up time of 19.7 +/- 8.5months. A second ablation attempt was performed in 20 patients and was successful in 16/20 patients (80%). Overall, long-term success rate was 92.3%.Conclusion p id=Par3 In this retrospective multicenter study, the outcome of catheter ablation for asymptomatic preexcitation in children and adolescents irrespective of antegrade AP conduction properties is summarized. The complication rate was low and success rate was high, the latter mainly depending on pathway location. The promising results of the study may have future impact on the ongoing risk-benefit discussion regarding catheter ablation in the setting of asymptomatic preexcitation in children and adolescents.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Telishevska, MartaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hebe, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paul, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nuernberg, J. H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krause, U.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gebauer, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gass, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Balmer, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berger, F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Molatta, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Emmel, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lawrenz, W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kriebel, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hessling, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-147145
DOI: 10.1007/s00392-018-1397-x
Journal or Publication Title: Clin. Res. Cardiol.
Volume: 108
Number: 6
Page Range: S. 683 - 691
Date: 2019
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1861-0692
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
WOLFF-PARKINSON-WHITE; EXPERT CONSENSUS STATEMENT; RADIOFREQUENCY ABLATION; CARDIAC ABLATION; CHILDREN; RISK; RECURRENCE; WPWMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14714

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