Stark, Christina, Duran, Ibrahim ORCID: 0000-0003-4044-8822, Martakis, Kyriakos
ORCID: 0000-0003-3982-0914, Spiess, Karoline, Semler, Oliver
ORCID: 0000-0003-0029-7556 and Schoenau, Eckhard
(2020).
Effect of Long-Term Repeated Interval Rehabilitation on the Gross Motor Function Measure in Children with Cerebral Palsy.
Neuropediatrics, 51 (6).
S. 407 - 417.
STUTTGART:
GEORG THIEME VERLAG KG.
ISSN 1439-1899
Abstract
Background The efficacy of interventions for cerebral palsy (CP) has been frequently investigated with inconclusive results and motor function measured by the Gross Motor Function Measure (GMFM-66) is common. Objective In this observational analysis, we quantify the GMFM-66 change scores of the second and third year of a multimodal rehabilitation program (interval rehabilitation including home-based, vibration-assisted training) in children with CP. Methods The study was a retrospective analysis of children with CP (2-13 years) participating for a second ( n =262) and third year ( n =86) in the rehabilitation program with GMFM-66 scores at start (M0), after 4 months (M4) of intensive training, and after 8 months of follow-up (M12). A method was previously developed to differentiate between possible treatment effects and expected development under standard of care for GMFM-66 scores using Cohen's d effect size (ES; size of difference). Results After the treatment phase of 4 months (M4) in the second year, 125 of 262 children were responder (ES >= 0.2) and 137 children nonresponder (ES<0.2); mean ES for nonresponder was -0.212 (trivial) and for responder 0.836 (large). After M4 in the third year, 43 children of 86 were responder (ES=0.881 [large]) and 43 nonresponder (ES=-0.124 [trivial]). Discussion and Conclusion Repeated rehabilitation shows a large additional treatment effect to standard of care in 50% of children which is likely due to the intervention, because in the follow-up period (standard of care), no additional treatment effect was observed and the children followed their expected development.
Item Type: | Journal Article | ||||||||||||||||||||||||||||
Creators: |
|
||||||||||||||||||||||||||||
URN: | urn:nbn:de:hbz:38-314784 | ||||||||||||||||||||||||||||
DOI: | 10.1055/s-0040-1715489 | ||||||||||||||||||||||||||||
Journal or Publication Title: | Neuropediatrics | ||||||||||||||||||||||||||||
Volume: | 51 | ||||||||||||||||||||||||||||
Number: | 6 | ||||||||||||||||||||||||||||
Page Range: | S. 407 - 417 | ||||||||||||||||||||||||||||
Date: | 2020 | ||||||||||||||||||||||||||||
Publisher: | GEORG THIEME VERLAG KG | ||||||||||||||||||||||||||||
Place of Publication: | STUTTGART | ||||||||||||||||||||||||||||
ISSN: | 1439-1899 | ||||||||||||||||||||||||||||
Language: | English | ||||||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||||||
Uncontrolled Keywords: |
|
||||||||||||||||||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/31478 |
Downloads
Downloads per month over past year
Altmetric
Export
Actions (login required)
![]() |
View Item |