Ballantyne, Kaye N., Ralf, Arwin, Aboukhalid, Rachid, Achakzai, Niaz M.
ORCID: 0000-0002-8872-6046, Anjos, Maria J., Ayub, Qasim
ORCID: 0000-0003-3291-0917, Balazic, Joze, Ballantyne, Jack, Ballard, David J., Berger, Burkhard, Bobillo, Cecilia, Bouabdellah, Mehdi, Burri, Helen, Capal, Tomas, Caratti, Stefano
ORCID: 0000-0002-8876-9724, Cardenas, Jorge, Cartault, Francois, Carvalho, Elizeu F., Carvalho, Monica, Cheng, Baowen, Coble, Michael D., Comas, David
ORCID: 0000-0002-5075-0956, Corach, Daniel, D'Amato, Maria E., Davison, Sean, de Knijff, Peter
ORCID: 0000-0002-0899-771X, De Ungria, Maria Corazon A., Decorte, Ronny, Dobosz, Tadeusz
ORCID: 0000-0003-0413-9109, Dupuy, Berit M., Elmrghni, Samir, Gliwinski, Mateusz, Gomes, Sara C., Grol, Laurens, Haas, Cordula
ORCID: 0000-0001-8122-1427, Hanson, Erin, Henke, Juergen, Henke, Lotte, Herrera-Rodriguez, Fabiola, Hill, Carolyn R., Holmlund, Gunilla, Honda, Katsuya, Immel, Uta-Dorothee, Inokuchi, Shota, Jobling, Mark A., Kaddura, Mahmoud, Kim, Jong S., Kim, Soon H., Kim, Wook, King, Turi E., Klausriegler, Eva, Kling, Daniel, Kovacevic, Lejla, Kovatsi, Leda, Krajewski, Pawel, Kravchenko, Sergey, Larmuseau, Maarten H. D., Lee, Eun Young, Lessig, Ruediger, Livshits, Ludmila A., Marjanovic, Damir
ORCID: 0000-0002-7472-4525, Minarik, Marek
ORCID: 0000-0002-0615-6116, Mizuno, Natsuko, Moreira, Helena, Morling, Niels
ORCID: 0000-0002-9463-5087, Mukherjee, Meeta, Munier, Patrick, Nagaraju, Javaregowda, Neuhuber, Franz, Nie, Shengjie, Nilasitsataporn, Premlaphat, Nishi, Takeki
ORCID: 0000-0002-6582-097X, Oh, Hye H., Olofsson, Jill
ORCID: 0000-0002-9527-6573, Onofri, Valerio
ORCID: 0000-0002-1294-1444, Palo, Jukka U., Pamjav, Horolma, Parson, Walther
ORCID: 0000-0002-5692-2392, Petlach, Michal, Phillips, Christopher
ORCID: 0000-0002-9601-0128, Ploski, Rafal
ORCID: 0000-0001-6286-5526, Prasad, Samayamantri P. R., Primorac, Dragan, Purnomo, Gludhug A., Purps, Josephine, Rangel-Villalobos, Hector, Rebala, Krzysztof
ORCID: 0000-0003-2236-7455, Rerkamnuaychoke, Budsaba, Rey Gonzalez, Danel, Robino, Carlo
ORCID: 0000-0003-1187-7732, Roewer, Lutz
ORCID: 0000-0001-9383-4941, Rosa, Alexandra
ORCID: 0000-0002-1827-6828, Sajantila, Antti
ORCID: 0000-0003-4117-5248, Sala, Andrea, Salvador, Jazelyn M., Sanz, Paula, Schmitt, Cornelia, Sharma, Anil K., Silva, Dayse A., Shin, Kyoung-Jin, Sijen, Titia, Sirker, Miriam
ORCID: 0000-0003-2979-4257, Sivakova, Daniela, Skaro, Vedrana
ORCID: 0000-0002-8275-867X, Solano-Matamoros, Carlos, Souto, Luis, Stenzl, Vlastimil, Sudoyo, Herawati, Syndercombe-Court, Denise, Tagliabracci, Adriano
ORCID: 0000-0002-4434-0475, Taylor, Duncan
ORCID: 0000-0003-0633-7424, Tillmar, Andreas, Tsybovsky, Iosif S., Tyler-Smith, Chris, van der Gaag, Kristiaan J., Vanek, Daniel, Volgyi, Antonia, Ward, Denise, Willemse, Patricia, Yap, Eric P. H., Yong, Rita Y. Y., Pajnic, Irena Zupanic and Kayser, Manfred
(2014).
Toward Male Individualization with Rapidly Mutating Y-Chromosomal Short Tandem Repeats.
Hum. Mutat., 35 (8).
S. 1021 - 1033.
HOBOKEN:
WILEY.
ISSN 1098-1004
Full text not available from this repository.
Abstract
Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutating (RM) Y-STRs in 14,644 related and unrelated males from 111 worldwide populations. Strikingly, >99% of the 12,272 unrelated males were completely individualized. Haplotype diversity was extremely high (global: 0.9999985, regional: 0.99836-0.9999988). Haplotype sharing between populations was almost absent except for six (0.05%) of the 12,156 haplotypes. Haplotype sharing within populations was generally rare (0.8% nonunique haplotypes), significantly lower in urban (0.9%) than rural (2.1%) and highest in endogamous groups (14.3%). Analysis of molecular variance revealed 99.98% of variation within populations, 0.018% among populations within groups, and 0.002% among groups. Of the 2,372 newly and 156 previously typed male relative pairs, 29% were differentiated including 27% of the 2,378 father-son pairs. Relative to Yfiler, haplotype diversity was increased in 86% of the populations tested and overall male relative differentiation was raised by 23.5%. Our study demonstrates the value of RMY-STRs in identifying and separating unrelated and related males and provides a reference database. Published 2014 Wiley Periodicals, Inc.**
Item Type: |
Journal Article
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Creators: |
Creators | Email | ORCID | ORCID Put Code |
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Ballantyne, Kaye N. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Ralf, Arwin | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Aboukhalid, Rachid | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Achakzai, Niaz M. | UNSPECIFIED | orcid.org/0000-0002-8872-6046 | UNSPECIFIED | Anjos, Maria J. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Ayub, Qasim | UNSPECIFIED | orcid.org/0000-0003-3291-0917 | UNSPECIFIED | Balazic, Joze | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Ballantyne, Jack | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Ballard, David J. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Berger, Burkhard | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Bobillo, Cecilia | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Bouabdellah, Mehdi | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Burri, Helen | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Capal, Tomas | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Caratti, Stefano | UNSPECIFIED | orcid.org/0000-0002-8876-9724 | UNSPECIFIED | Cardenas, Jorge | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Cartault, Francois | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Carvalho, Elizeu F. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Carvalho, Monica | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Cheng, Baowen | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Coble, Michael D. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Comas, David | UNSPECIFIED | orcid.org/0000-0002-5075-0956 | UNSPECIFIED | Corach, Daniel | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | D'Amato, Maria E. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Davison, Sean | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | de Knijff, Peter | UNSPECIFIED | orcid.org/0000-0002-0899-771X | UNSPECIFIED | De Ungria, Maria Corazon A. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Decorte, Ronny | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Dobosz, Tadeusz | UNSPECIFIED | orcid.org/0000-0003-0413-9109 | UNSPECIFIED | Dupuy, Berit M. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Elmrghni, Samir | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Gliwinski, Mateusz | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Gomes, Sara C. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Grol, Laurens | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Haas, Cordula | UNSPECIFIED | orcid.org/0000-0001-8122-1427 | UNSPECIFIED | Hanson, Erin | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Henke, Juergen | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Henke, Lotte | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Herrera-Rodriguez, Fabiola | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Hill, Carolyn R. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Holmlund, Gunilla | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Honda, Katsuya | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Immel, Uta-Dorothee | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Inokuchi, Shota | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Jobling, Mark A. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kaddura, Mahmoud | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kim, Jong S. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kim, Soon H. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kim, Wook | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | King, Turi E. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Klausriegler, Eva | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kling, Daniel | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kovacevic, Lejla | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kovatsi, Leda | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Krajewski, Pawel | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kravchenko, Sergey | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Larmuseau, Maarten H. D. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Lee, Eun Young | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Lessig, Ruediger | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Livshits, Ludmila A. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Marjanovic, Damir | UNSPECIFIED | orcid.org/0000-0002-7472-4525 | UNSPECIFIED | Minarik, Marek | UNSPECIFIED | orcid.org/0000-0002-0615-6116 | UNSPECIFIED | Mizuno, Natsuko | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Moreira, Helena | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Morling, Niels | UNSPECIFIED | orcid.org/0000-0002-9463-5087 | UNSPECIFIED | Mukherjee, Meeta | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Munier, Patrick | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Nagaraju, Javaregowda | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Neuhuber, Franz | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Nie, Shengjie | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Nilasitsataporn, Premlaphat | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Nishi, Takeki | UNSPECIFIED | orcid.org/0000-0002-6582-097X | UNSPECIFIED | Oh, Hye H. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Olofsson, Jill | UNSPECIFIED | orcid.org/0000-0002-9527-6573 | UNSPECIFIED | Onofri, Valerio | UNSPECIFIED | orcid.org/0000-0002-1294-1444 | UNSPECIFIED | Palo, Jukka U. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Pamjav, Horolma | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Parson, Walther | UNSPECIFIED | orcid.org/0000-0002-5692-2392 | UNSPECIFIED | Petlach, Michal | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Phillips, Christopher | UNSPECIFIED | orcid.org/0000-0002-9601-0128 | UNSPECIFIED | Ploski, Rafal | UNSPECIFIED | orcid.org/0000-0001-6286-5526 | UNSPECIFIED | Prasad, Samayamantri P. R. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Primorac, Dragan | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Purnomo, Gludhug A. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Purps, Josephine | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Rangel-Villalobos, Hector | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Rebala, Krzysztof | UNSPECIFIED | orcid.org/0000-0003-2236-7455 | UNSPECIFIED | Rerkamnuaychoke, Budsaba | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Rey Gonzalez, Danel | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Robino, Carlo | UNSPECIFIED | orcid.org/0000-0003-1187-7732 | UNSPECIFIED | Roewer, Lutz | UNSPECIFIED | orcid.org/0000-0001-9383-4941 | UNSPECIFIED | Rosa, Alexandra | UNSPECIFIED | orcid.org/0000-0002-1827-6828 | UNSPECIFIED | Sajantila, Antti | UNSPECIFIED | orcid.org/0000-0003-4117-5248 | UNSPECIFIED | Sala, Andrea | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Salvador, Jazelyn M. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Sanz, Paula | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Schmitt, Cornelia | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Sharma, Anil K. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Silva, Dayse A. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Shin, Kyoung-Jin | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Sijen, Titia | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Sirker, Miriam | UNSPECIFIED | orcid.org/0000-0003-2979-4257 | UNSPECIFIED | Sivakova, Daniela | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Skaro, Vedrana | UNSPECIFIED | orcid.org/0000-0002-8275-867X | UNSPECIFIED | Solano-Matamoros, Carlos | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Souto, Luis | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Stenzl, Vlastimil | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Sudoyo, Herawati | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Syndercombe-Court, Denise | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Tagliabracci, Adriano | UNSPECIFIED | orcid.org/0000-0002-4434-0475 | UNSPECIFIED | Taylor, Duncan | UNSPECIFIED | orcid.org/0000-0003-0633-7424 | UNSPECIFIED | Tillmar, Andreas | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Tsybovsky, Iosif S. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Tyler-Smith, Chris | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | van der Gaag, Kristiaan J. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Vanek, Daniel | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Volgyi, Antonia | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Ward, Denise | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Willemse, Patricia | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Yap, Eric P. H. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Yong, Rita Y. Y. | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Pajnic, Irena Zupanic | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED | Kayser, Manfred | UNSPECIFIED | UNSPECIFIED | UNSPECIFIED |
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URN: |
urn:nbn:de:hbz:38-433313 |
DOI: |
10.1002/humu.22599 |
Journal or Publication Title: |
Hum. Mutat. |
Volume: |
35 |
Number: |
8 |
Page Range: |
S. 1021 - 1033 |
Date: |
2014 |
Publisher: |
WILEY |
Place of Publication: |
HOBOKEN |
ISSN: |
1098-1004 |
Language: |
English |
Faculty: |
Unspecified |
Divisions: |
Unspecified |
Subjects: |
no entry |
Uncontrolled Keywords: |
Keywords | Language |
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STR HAPLOTYPES; RECOMMENDATIONS; HISTORY; ISFG | Multiple languages | Genetics & Heredity | Multiple languages |
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URI: |
http://kups.ub.uni-koeln.de/id/eprint/43331 |
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