Universität zu Köln

Gaisendrees, Christopher ORCID: 0000-0002-7232-3330, Walter, Sebastian G., Elderia, Ahmed ORCID: 0000-0002-6859-5384, Vollmer, Mattias, Kaya, Suereyya, Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Eghbalzadeh, Kaveh, Sabashnikov, Anton, Kahlert, Heike Anelie, Deppe, Antje-Christin, Boll, Boris, Madershahian, Navid and Wahlers, Thorsten (2021). Adequate anticoagulation and ECMO therapy in COVID-19 patients with severe pulmonary embolism. Perfusion-UK, 36 (6). S. 575 - 582. LONDON: SAGE PUBLICATIONS LTD. ISSN 1477-111X

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Abstract

SARS-CoV-2 (COVID-19) infections have been recently shown to be associated with a high rate of thromboembolic events due to pro-coagulative mechanisms that have not yet been fully understood. This paper reports on a 55-year-old female COVID-19 patient with severe ARDS and pulmonary embolism (PE) complicated by cardiogenic shock after 12 days of hospitalization under initial prophylactic anticoagulation with low molecular weight heparin (LMWH). An ultima-ratio va (veno-arterial) ECMO implantation and subsequent rapid upgrade to vvaECMO due to insufficient oxygenation was performed. The patient developed severe coagulopathy with intrapulmonary bleeding. The present report aims to highlight and discuss the pros and cons of various anticoagulation strategies in COVID-19 patients focusing on current scientific debates to address this frequently observed complication in the current situation worldwide.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gaisendrees, Christopher UNSPECIFIED orcid.org/0000-0002-7232-3330 UNSPECIFIED Walter, Sebastian G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Elderia, Ahmed UNSPECIFIED orcid.org/0000-0002-6859-5384 UNSPECIFIED Vollmer, Mattias UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaya, Suereyya UNSPECIFIED UNSPECIFIED UNSPECIFIED Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Eghbalzadeh, Kaveh UNSPECIFIED UNSPECIFIED UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Kahlert, Heike Anelie UNSPECIFIED UNSPECIFIED UNSPECIFIED Deppe, Antje-Christin UNSPECIFIED UNSPECIFIED UNSPECIFIED Boll, Boris UNSPECIFIED UNSPECIFIED UNSPECIFIED Madershahian, Navid UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-564082
DOI:	10.1177/0267659120979887
Journal or Publication Title:	Perfusion-UK
Volume:	36
Number:	6
Page Range:	S. 575 - 582
Date:	2021
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1477-111X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MANAGEMENT Multiple languages Cardiac & Cardiovascular Systems; Peripheral Vascular Disease Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/56408