Szczepanowska, Karolina ORCID: 0000-0003-4689-2350 and Trifunovic, Aleksandra (2021). Tune instead of destroy: How proteolysis keeps OXPHOS in shape. Biochim. Biophys. Acta-Bioenerg., 1862 (4). AMSTERDAM: ELSEVIER. ISSN 1879-2650
Full text not available from this repository.Abstract
Mitochondria are highly dynamic and stress-responsive organelles that are renewed, maintained and removed by a number of different mechanisms. Recent findings bring more evidence for the focused, defined, and regulatory function of the intramitochondrial proteases extending far beyond the traditional concepts of damage control and stress responses. Until recently, the macrodegradation processes, such as mitophagy, were promoted as the major regulator of OXPHOS remodelling and turnover. However, the spatiotemporal dynamics of the OXPHOS system can be greatly modulated by the intrinsic mitochondrial mechanisms acting apart from changes in the global mitochondrial dynamics. This, in turn, may substantially contribute to the shaping of the metabolic status of the cell.
Item Type: | Journal Article | ||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-574410 | ||||||||||||
DOI: | 10.1016/j.bbabio.2020.148365 | ||||||||||||
Journal or Publication Title: | Biochim. Biophys. Acta-Bioenerg. | ||||||||||||
Volume: | 1862 | ||||||||||||
Number: | 4 | ||||||||||||
Date: | 2021 | ||||||||||||
Publisher: | ELSEVIER | ||||||||||||
Place of Publication: | AMSTERDAM | ||||||||||||
ISSN: | 1879-2650 | ||||||||||||
Language: | English | ||||||||||||
Faculty: | Unspecified | ||||||||||||
Divisions: | Unspecified | ||||||||||||
Subjects: | no entry | ||||||||||||
Uncontrolled Keywords: |
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URI: | http://kups.ub.uni-koeln.de/id/eprint/57441 |
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