Universität zu Köln

Journal Article

Becker, Finn, Joerg, Vincent, Hupe, Marie C., Roth, Doris, Krupar, Rosemarie, Lubczyk, Verena, Kuefer, Rainer, Sailer, Verena, Duensing, Stefan, Kirfel, Jutta, Merseburger, Axel S., Braegelmann, Johannes, Perner, Sven and Offermann, Anne (2020). Increased mediator complex subunit CDK19 expression associates with aggressive prostate cancer. Int. J. Cancer, 146 (2). S. 577 - 589. HOBOKEN: WILEY. ISSN 1097-0215

Borchmann, Sven, Selenz, Carolin, Lohmann, Mia, Ludwig, Hanna, Gassa, Asmae, Braegelmann, Johannes, Lohneis, Philipp, Meder, Lydia, Mattlener, Julia, Breid, Sara, Nill, Marieke, Fassunke, Jana, Wisdom, Amy J., Compes, Anik, Gathof, Birgit, Alakus, Hakan, Kirsch, David, Hekmat, Khosro, Buettner, Reinhard, Reinhardt, H. Christian, Hallek, Michael ORCID: 0000-0002-7425-4455 and Ullrich, Roland T. (2022). Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors. J. Immunother. Cancer, 10 (10). LONDON: BMJ PUBLISHING GROUP. ISSN 2051-1426

Braegelmann, Johannes, Barahona Ponce, Carol, Marcelain, Katherine, Roessler, Stephanie ORCID: 0000-0002-5333-5942, Goeppert, Benjamin, Gallegos, Ivan, Colombo, Alicia, Sanhueza, Veronica, Morales, Erik, Rivera, Maria Teresa, de Toro, Gonzalo, Ortega, Alejandro, Muller, Bettina, Gabler, Fernando, Scherer, Dominique, Waldenberger, Melanie, Reischl, Eva, Boekstegers, Felix, Garate-Calderon, Valentina, Umu, Sinan U., Rounge, Trine B., Popanda, Odilia and Lorenzo Bermejo, Justo (2021). Epigenome-Wide Analysis of Methylation Changes in the Sequence of Gallstone Disease, Dysplasia, and Gallbladder Cancer. Hepatology, 73 (6). S. 2293 - 2311. HOBOKEN: WILEY. ISSN 1527-3350

Braegelmann, Johannes and Bermejo, Justo Lorenzo (2019). A comparative analysis of cell-type adjustment methods for epigenome-wide association studies based on simulated and real data sets. Brief. Bioinform., 20 (6). S. 2055 - 2066. OXFORD: OXFORD UNIV PRESS. ISSN 1477-4054

Braegelmann, Johannes, Boehm, Stefanie, Guthrie, Matthew R., Mollaoglu, Gurkan ORCID: 0000-0003-0679-7463, Oliver, Trudy G. and Sos, Martin L. (2017). Family matters: How MYC family oncogenes impact small cell lung cancer. Cell Cycle, 16 (16). S. 1489 - 1499. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1551-4005

Braegelmann, Johannes, Dammert, Marcel A., Dietlein, Felix, Heuckmann, Johannes M., Choidas, Axel, Boehm, Stefanie, Richters, Andre, Basu, Debjit, Tischler, Verena ORCID: 0000-0002-6673-8329, Lorenz, Carina, Habenberger, Peter, Fang, Zhizhou, Ortiz-Cuaran, Sandra, Leenders, Frauke, Eickhoff, Jan, Koch, Uwe, Getlik, Matthaeus, Termathe, Martin ORCID: 0000-0002-5618-4633, Sallouh, Muhammad, Greff, Zoltan, Varga, Zoltan, Balke-Want, Hyatt, French, Christopher A., Peifer, Martin ORCID: 0000-0002-5243-5503, Reinhardt, H. Christian, Orfi, Laszlo ORCID: 0000-0001-6149-2385, Keri, Gyorgy, Ansen, Sascha, Heukamp, Lukas C., Buettner, Reinhard, Rauh, Daniel, Klebl, Bert M., Thomas, Roman K. and Sos, Martin L. (2017). Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma. Cell Reports, 20 (12). S. 2833 - 2846. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Braegelmann, Johannes, Lorenz, Carina, Borchmann, Sven ORCID: 0000-0001-6662-6864, Nishii, Kazuya, Wegner, Julia ORCID: 0000-0001-8103-8040, Meder, Lydia, Ostendorp, Jenny, Ast, David F., Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A., Plenker, Dennis, Klein, Sebastian ORCID: 0000-0002-2188-9377, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K., Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S., Li, Henry, Schmitt, Clemens A. ORCID: 0000-0002-4731-2226, George, Julie, Thomas, Roman K., von Karstedt, Silvia, Hartmann, Gunther, Buettner, Reinhard, Ullrich, Roland T., Siveke, Jens T., Ohashi, Kadoaki, Schlee, Martin ORCID: 0000-0003-3671-7639 and Sos, Martin L. (2021). MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nat. Commun., 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Deng, Mario, Braegelmann, Johannes, Kryukov, Ivan, Saraiva-Agostinho, Nuno ORCID: 0000-0002-5549-105X and Perner, Sven (2017). FirebrowseR: an R client to the Broad Institute's Firehose Pipeline. Database. OXFORD: OXFORD UNIV PRESS. ISSN 1758-0463

Dressler, Franz F., Braegelmann, Johannes, Reischl, Markus and Perner, Sven (2022). Normics: Proteomic Normalization by Variance and Data-Inherent Correlation Structure. Mol. Cell. Proteomics, 21 (9). AMSTERDAM: ELSEVIER. ISSN 1535-9484

Fassunke, Jana, Mueller, Fabienne, Keul, Marina, Michels, Sebastian, Dammert, Marcel A., Schmitt, Anna, Plenker, Dennis, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Heydt, Carina, Braegelmann, Johannes, Tumbrink, Hannah L., Alber, Yannic, Klein, Sebastian, Heimsoeth, Alena, Dahmen, Ilona, Fischers, Rieke N., Scheffler, Matthias, Ihle, Michaela A., Priesner, Vanessa, Scheel, Andreas H., Wagener, Svenja, Kron, Anna, Frank, Konrad, Garbert, Katia, Persigehl, Thorsten, Puesken, Michael, Haneder, Stefan, Schaaf, Bernhard, Rodermann, Ernst, Engel-Riedel, Walburga, Felip, Enriqueta, Smit, Egbert F., Merkelbach-Bruse, Sabine, Reinhardt, H. Christian, Kast, Stefan M., Wolf, Juergen, Rauh, Daniel, Buettner, Reinhard and Sos, Martin L. (2018). Overcoming EGFR(G724S)-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Lategahn, Jonas, Tumbrink, Hannah L., Schultz-Fademrecht, Carsten, Heimsoeth, Alena, Werr, Lisa ORCID: 0000-0002-3697-4136, Niggenaber, Janina, Keul, Marina, Parmaksiz, Fatma ORCID: 0009-0003-3771-7128, Baumann, Matthias, Menninger, Sascha, Zent, Eldar, Landel, Ina, Weisner, Joern, Jeyakumar, Kirujan ORCID: 0000-0002-0184-6775, Heyden, Leonie, Russ, Nicole, Mueller, Fabienne, Lorenz, Carina, Braegelmann, Johannes, Spille, Inga, Grabe, Tobias ORCID: 0000-0002-8287-1971, Mueller, Matthias P., Heuckmann, Johannes M., Klebl, Bert M., Nussbaumer, Peter, Sos, Martin L. and Rauh, Daniel (2022). Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors. J. Med. Chem., 65 (9). S. 6643 - 6656. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Lemster, Anna-Lena, Sievers, Elisabeth, Pasternack, Helen ORCID: 0000-0003-2386-2300, Lazar-Karsten, Pamela, Kluemper, Niklas, Sailer, Verena, Offermann, Anne, Braegelmann, Johannes, Perner, Sven and Kirfel, Jutta (2022). Histone Demethylase KDM5C Drives Prostate Cancer Progression by Promoting EMT. Cancers, 14 (8). BASEL: MDPI. ISSN 2072-6694

Malchers, Florian, Ercanoglu, Meryem, Schuette, Daniel ORCID: 0000-0002-4746-537X, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Tischler, Verena ORCID: 0000-0002-6673-8329, Michels, Sebastian, Dahmen, Ilona, Braegelmann, Johannes, Menon, Roopika, Heuckmann, Johannes M., George, Julie, Ansen, Sascha, Sos, Martin L., Soltermann, Alex, Peifer, Martin ORCID: 0000-0002-5243-5503, Wolf, Juergen, Buettner, Reinhard and Thomas, Roman K. (2017). Mechanisms of Primary Drug Resistance in FGFR1-Amplified Lung Cancer. Clin. Cancer Res., 23 (18). S. 5527 - 5537. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Michels, Sebastian, Heydt, Carina, van Veggel, Bianca, Deschler-Baier, Barbara, Pardo, Nuria, Monkhorst, Kim, Ruesseler, Vanessa, Stratmann, Jan, Griesinger, Frank, Steinhauser, Susanne, Kostenko, Anna, Diebold, Joachim, Fassunke, Jana, Fischer, Rieke, Engel-Riedel, Walburga, Gautschi, Oliver, Geissinger, Eva, Haneder, Stefan, Ihle, Michaela A., Kopp, Hans-Georg, de Langen, Adrianus J., Martinez-Marti, Alex, Nogova, Lucia, Persigehl, Thorsten, Plenker, Dennis, Puesken, Michael, Rodermann, Ernst, Rosenwald, Andreas, Scheel, Andreas H., Scheffler, Matthias, Spengler, Werner, Seggewiss-Bernhardt, Ruth, Braegelmann, Johannes, Sebastian, Martin, Vrugt, Bart, Hellmich, Martin, Sos, Martin L., Heukamp, Lukas C., Felip, Enriqueta, Merkelbach-Bruse, Sabine, Smit, Egbert F., Buettner, Reinhard and Wolf, Juergen (2019). Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer. JCO Precis. Oncol., 3. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 2473-4284

Mollaoglu, Gurkan ORCID: 0000-0003-0679-7463, Guthrie, Matthew R., Boehm, Stefanie, Braegelmann, Johannes, Can, Ismail, Ballieu, Paul M., Marx, Annika, George, Julie, Heinen, Christine, Chalishazar, Milind D., Cheng, Haixia, Ireland, Abbie S., Denning, Kendall E., Mukhopadhyay, Anandaroop, Vahrenkamp, Jeffery M., Berrett, Kristofer C., Mosbruger, Timothy L., Wang, Jun, Kohan, Jessica L., Salama, Mohamed E., Witt, Benjamin L., Peifer, Martin ORCID: 0000-0002-5243-5503, Thomas, Roman K., Gertz, Jason ORCID: 0000-0001-7568-6789, Johnson, Jane E., Gazdar, Adi F., Wechsler-Reya, Robert J., Sos, Martin L. and Oliver, Trudy G. (2017). MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition. Cancer Cell, 31 (2). S. 270 - 286. CAMBRIDGE: CELL PRESS. ISSN 1878-3686

Mueller, Fabienne, Lim, Jonathan K. M., Bebber, Christina M., Seidel, Eric ORCID: 0000-0003-3334-3950, Tishina, Sofya, Dahlhaus, Alina, Stroh, Jenny, Beck, Julia, Yapici, Fatma Isil, Nakayama, Keiko ORCID: 0000-0003-0134-6401, Fernandez, Lucia Torres, Braegelmann, Johannes, Leprivier, Gabriel and von Karstedt, Silvia . Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation. Cell Death Differ.. LONDON: SPRINGERNATURE. ISSN 1476-5403

Offermann, Anne, Joerg, Vincent, Becker, Finn, Roesch, Marie C., Kang, Duan, Lemster, Anna-Lena, Tharun, Lars, Behrends, Jochen ORCID: 0000-0002-0648-8911, Merseburger, Axel S., Culig, Zoran, Sailer, Verena, Braegelmann, Johannes, Kirfel, Jutta and Perner, Sven (2022). Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer. Am. J. Pathol., 192 (5). S. 813 - 824. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1525-2191

Offermann, Anne, Joerg, Vincent, Hupe, Marie C., Becker, Finn, Mueller, Marten, Braegelmann, Johannes, Kirfel, Jutta, Merseburger, Axel S., Sailer, Verena, Tharun, Lars and Perner, Sven (2021). CDK19 as a diagnostic marker for high-grade prostatic intraepithelial neoplasia. Hum. Pathol., 117. S. 60 - 68. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1532-8392

Paulsen, Finn-Ole, Idel, Christian, Ribbat-Idel, Julika, Kuppler, Patrick ORCID: 0000-0002-5667-8481, Klapper, Luise, Rades, Dirk, Bruchhage, Karl-Ludwig, Wollenberg, Barbara, Braegelmann, Johannes, Perner, Sven and Offermann, Anne (2020). CDK19 as a Potential HPV-Independent Biomarker for Recurrent Disease in HNSCC. Int. J. Mol. Sci., 21 (15). BASEL: MDPI. ISSN 1422-0067

Pfister, Roman, Braegelmann, Johannes, Michels, Guido, Wareham, Nick J., Luben, Robert and Khaw, Kay-Tee (2015). Performance of the CHARGE-AF risk model for incident atrial fibrillation in the EPIC Norfolk cohort. Eur. J. Prev. Cardiol., 22 (7). S. 932 - 940. LONDON: SAGE PUBLICATIONS LTD. ISSN 2047-4881

Pfister, Roman, Michels, Guido, Braegelmann, Johannes, Sharp, Stephen J., Luben, Robert, Wareham, Nick J. and Khaw, Kay-Tee (2014). Plasma vitamin C and risk of hospitalisation with diagnosis of atrial fibrillation in men and women in EPIC-Norfolk prospective study. Int. J. Cardiol., 177 (3). S. 830 - 836. CLARE: ELSEVIER IRELAND LTD. ISSN 1874-1754

Plenker, Dennis, Bertrand, Miriam, de Langen, Adrianus J., Riedel, Richard, Lorenz, Carina, Scheel, Andreas H., Mueller, Judith, Braegelmann, Johannes, Dassler-Plenker, Juliane, Kobe, Carsten, Persigehl, Thorsten, Kluge, Alexander, Wurdinger, Thomas, Schellen, Pepijn, Hartmann, Gunther ORCID: 0000-0003-1021-2018, Zacherle, Tobias, Menon, Roopika, Thunnissen, Erik, Buettner, Reinhard, Griesinger, Frank, Wolf, Juergen, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Sos, Martin L. and Heuckmann, Johannes M. (2018). Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients. Clin. Cancer Res., 24 (6). S. 1337 - 1344. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Plenker, Dennis, Lorenz, Carina, Bertrand, Miriam, Riedel, Richard, de Langen, Joop, Braegelmann, Johannes, Buettner, Reinhard, Wolf, Juergen, Thomas, Roman K., Heuckmann, Johannes and Sos, Martin L. (2018). Targeting structural RET and MET kinase alterations in lung adenocarcinoma patients. Cancer Res., 78 (13). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Plenker, Dennis, Riedel, Maximilian, Braegelmann, Johannes, Dammert, Marcel A., Chauhan, Rakhee, Knowles, Phillip P., Lorenz, Carina, Keul, Marina, Buehrmann, Mike, Pagel, Oliver, Tischler, Verena ORCID: 0000-0002-6673-8329, Scheel, Andreas H., Schtte, Daniel, Song, Yanrui, Stark, Justina, Mrugalla, Florian ORCID: 0000-0002-6281-6051, Alber, Yannic, Richters, Andre, Engel, Julian, Leenders, Frauke, Heuckmann, Johannes M., Wolf, Juergen, Diebold, Joachim, Pall, Georg, Peifer, Martin ORCID: 0000-0002-5243-5503, Aerts, Maarten, Gevaert, Kris ORCID: 0000-0002-4237-0283, Zahedi, Rene P., Buettner, Reinhard, Shokat, Kevan M., McDonald, Neil Q., Kast, Stefan M., Gautschi, Oliver, Thomas, Roman K. and Sos, Martin L. (2017). Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Sci. Transl. Med., 9 (394). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Schaufler, Diana, Ast, David F., Tumbrink, Hannah L., Abedpour, Nima, Maas, Lukas, Schwaebe, Ayla E., Spille, Inga, Lennartz, Stefanie, Fassunke, Jana, Aldea, Mihaela, Besse, Benjamin, Planchard, David, Nogova, Lucia, Michels, Sebastian, Kobe, Carsten, Persigehl, Thorsten, Westphal, Theresa, Koleczko, Sophia, Fischer, Rieke, Weber, Jan-Phillip, Altmueller, Janine, Thomas, Roman K., Merkelbach-Bruse, Sabine, Gautschi, Oliver, Mezquita, Laura, Buettner, Reinhard, Wolf, Juergen, Peifer, Martin, Braegelmann, Johannes, Scheffler, Matthias and Sos, Martin L. (2021). Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer. npj Precis. Oncol., 5 (1). BERLIN: NATURE PORTFOLIO. ISSN 2397-768X

Scheffler, Matthias, Ihle, Michaela A., Hein, Rebecca, Merkelbach-Bruse, Sabine, Braegelmann, Johannes, Scheel, Andreas H., Michels, Sebastian Yves Friedrich, Ueckeroth, Frank, Eisert, Anna, Gogl, Leonie, Frank, Rieke, Fischer, Rieke Nila, Koleczko, Sophia, Schaepers, Carsten, Kostenko, Anna, Kron, Florian, Hellmich, Martin, Sos, Martin L., Buettner, Reinhard and Wolf, Juergen (2016). Genetic heterogeneity of KRAS-mutated NSCLC: Co-occurrence of potentially targetable aberrations and evolutionary background. J. Clin. Oncol., 34 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Scheffler, Matthias, Ihle, Michaela A., Hein, Rebecca, Merkelbach-Bruse, Sabine, Scheel, Andreas H., Siemanowski, Janna, Braegelmann, Johannes, Kron, Anna, Abedpour, Nima, Ueckeroth, Frank, Schueller, Merle, Koleczko, Sophia, Michels, Sebastian, Fassunke, Jana, Pasternack, Helen, Heydt, Carina, Serke, Monika, Fischer, Rieke, Schulte, Wolfgang, Gerigk, Ulrich, Nogova, Lucia, Ko, Yon-Dschun, Abdulla, Diana S. Y., Riedel, Richard, Kambartel, Karl-Otto, Lorenz, Joachim, Sauerland, Imke, Randerath, Winfried, Kaminsky, Britta, Hagmeyer, Lars, Grohe, Christian, Eisert, Anna, Frank, Rieke, Gogl, Leonie, Schaepers, Carsten, Holzem, Alessandra, Hellmich, Martin, Thomas, Roman K., Peifer, Martin, Sos, Martin L., Buettner, Reinhard and Wolf, Juergen (2019). K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways. J. Thorac. Oncol., 14 (4). S. 606 - 617. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1556-1380

Selenz, Carolin, Compes, Anik, Nill, Marieke, Borchmann, Sven, Odenthal, Margarete ORCID: 0000-0002-2424-0960, Florin, Alexandra, Braegelmann, Johannes, Buettner, Reinhard, Meder, Lydia and Ullrich, Roland T. (2022). EGFR Inhibition Strongly Modulates the Tumour Immune Microenvironment in EGFR-Driven Non-Small-Cell Lung Cancer. Cancers, 14 (16). BASEL: MDPI. ISSN 2072-6694

Watermann, Christian ORCID: 0000-0002-6960-5863, Pasternack, Helen ORCID: 0000-0003-2386-2300, Idel, Christian, Ribbat-Idel, Julika, Braegelmann, Johannes, Kuppler, Patrick, Offermann, Anne, Jonigk, Danny, Kuehnel, Mark, Schroeck, Andreas, Dreyer, Eva, Rosero, Christian, Nathansen, Jacqueline, Dubrovska, Anna, Tharun, Lars, Kirfel, Jutta, Wollenberg, Barbara, Perner, Sven and Krupar, Rosemarie (2021). Recurrent HNSCC Harbor an Immunosuppressive Tumor Immune Microenvironment Suggesting Successful Tumor Immune Evasion. Clin. Cancer Res., 27 (2). S. 632 - 645. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265