Universität zu Köln

2022

Damanakis, Alexander, I, Wahler, Isabell, Fuchs, Hans, Loeser, Heike, Schroeder, Wolfgang, Zander, Thomas, Chon, Seung-Hun, Bruns, Christiane, Quaas, Alexander and Gebauer, Florian (2022). Integrin beta1 (ITGB1) as a prognostic marker in esophageal adenocarcinoma. Sci Rep, 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

Datta, Rabi R., Schran, Simon ORCID: 0000-0002-1092-9804, Persa, Oana-Diana, Aguilar, Claire, Thelen, Martin ORCID: 0000-0002-2785-9726, Lehmann, Jonas, Garcia-Marquez, Maria A., Wennhold, Kerstin, Preugszat, Ella, Zentis, Peter ORCID: 0000-0002-6999-132X, Von Bergwelt-Baildon, Michael S., Quaas, Alexander, Bruns, Christiane J., Kurschat, Christine, Mauch, Cornelia, Loeser, Heike, Stippel, Dirk L. and Schloesser, Hans A. (2022). Post-transplant Malignancies Show Reduced T-cell Abundance and Tertiary Lymphoid Structures as Correlates of Impaired Cancer Immunosurveillance. Clin. Cancer Res., 28 (8). S. 1712 - 1724. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Lohneis, Philipp, Rohmann, Julia, Gebauer, Florian, Hieggelke, Lena, Bruns, Christiane, Schroeder, Wolfgang, Buettner, Reinhard, Loeser, Heike and Quaas, Alexander (2022). International Tumor Budding Consensus Conference criteria determine the prognosis of oesophageal adenocarcinoma with poor response to neoadjuvant treatment. Pathol. Res. Pract., 232. MUNICH: ELSEVIER GMBH. ISSN 1618-0631

Schenk, Alexander, Esser, Tobias, Belen, Sergen ORCID: 0000-0001-9074-3198, Gunasekara, Nadira, Joisten, Niklas ORCID: 0000-0002-9947-8746, Winker, Matteo Thomas, Weike, Lea, Bloch, Wilhelm, Heidenreich, Axel, Herden, Jan, Loeser, Heike, Oganesian, Sabine, Theurich, Sebastian, Watzl, Carsten and Zimmer, Philipp (2022). Distinct distribution patterns of exercise-induced natural killer cell mobilization into the circulation and tumor tissue of patients with prostate cancer. Am. J. Physiol.-Cell Physiol., 323 (3). S. C879 - 6. Rockville: AMER PHYSIOLOGICAL SOC. ISSN 1522-1563

Schroeder, Wolfgang, Ghadimi, Markus P. H., Schloesser, Hans, Loeser, Heike, Schiller, Petra ORCID: 0000-0002-9957-1465, Zander, Thomas, Gebauer, Florian, Fuchs, Hans, Quaas, Alexander and Bruns, Christiane J. (2022). Long-Term Outcome After Histopathological Complete Response with and Without Nodal Metastases Following Multimodal Treatment of Esophageal Cancer. Ann. Surg. Oncol., 29 (7). S. 4419 - 4429. NEW YORK: SPRINGER. ISSN 1534-4681

2021

Gassa, Asmae, Fassunke, Jana, Schueten, Sarah, Kuhlmann, Luca, Scherer, Marie, Qien, Jie, Zhao, Yue, Michel, Max, Loeser, Heike, Wolf, Juergen, Buettner, Reinhard, Doerr, Fabian, Heldwein, Matthias, Hagmeyer, Lars, Frank, Konrad, Merkelbach-Bruse, Sabine, Quaas, Alexander, Bruns, Christiane, Hekmat, Khosro, Weiss, Jonathan, Wahlers, Thorsten and Alakus, Hakan (2021). Detection of circulating tumor DNA by digital droplet PCR in resectable lung cancer as a predictive tool for recurrence. Lung Cancer, 151. S. 91 - 97. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-8332

Klein, Sebastian ORCID: 0000-0002-2188-9377, Quaas, Alexander, Quantius, Jennifer, Loeser, Heike, Meinel, Jorn, Peifer, Martin, Wagner, Steffen ORCID: 0000-0003-0873-1601, Gattenloehner, Stefan, Wittekindt, Claus, Doeberitz, Magnus von Knebel, Prigge, Elena-Sophie, Langer, Christine, Noh, Ka-Won, Maltseva, Margaret, Reinhardt, Hans Christian, Buettner, Reinhard, Klussmann, Jens Peter ORCID: 0000-0002-8223-7954 and Wuerdemann, Nora (2021). Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains. Clin. Cancer Res., 27 (4). S. 1131 - 1139. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Popp, Felix C., Capino, Ingracia, Bartels, Joana, Damanakis, Alexander I., Li, Jiahui, Datta, Rabi R., Loeser, Heike ORCID: 0000-0003-4555-1327, Zhao, Yue ORCID: 0000-0002-6790-3402, Quaas, Alexander, Lohneis, Philipp and Bruns, Christiane J. (2021). Expression of Immune Checkpoint Regulators IDO, VISTA, LAG3, and TIM3 in Resected Pancreatic Ductal Adenocarcinoma. Cancers, 13 (11). BASEL: MDPI. ISSN 2072-6694

Quaas, Alexander, Pamuk, Aylin, Klein, Sebastian ORCID: 0000-0002-2188-9377, Quantius, Jennifer, Rehkaemper, Jan, Barutcu, Atakan G., Rueschoff, Josef, Zander, Thomas, Gebauer, Florian, Hillmer, Axel, Buettner, Reinhard, Schroeder, Wolfgang, Bruns, Christiane J., Loeser, Heike, Schoemig-Markiefka, Birgid and Alakus, Hakan (2021). Sex-specific prognostic effect of CD66b-positive tumor-infiltrating neutrophils (TANs) in gastric and esophageal adenocarcinoma. Gastric Cancer, 24 (6). S. 1213 - 1227. NEW YORK: SPRINGER. ISSN 1436-3305

Quaas, Alexander, Rehkaemper, Jan, Rueschoff, Josef, Pamuk, Aylin, Zander, Thomas, Hillmer, Axel, Siemanowski, Janna, Wittig, Jana, Buettner, Reinhard, Plum, Patrick, Popp, Felix, Gebauer, Florian, Bruns, Christiane Josephine, Loeser, Heike, Alakus, Hakan and Schoemig-Markiefka, Birgid (2021). Occurrence of High Microsatellite-Instability/Mismatch Repair Deficiency in Nearly 2,000 Human Adenocarcinomas of the Gastrointestinal Tract, Pancreas, and Bile Ducts: A Study From a Large German Comprehensive Cancer Center. Front. Oncol., 11. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2234-943X

Schoemig-Markiefka, Birgid, Eschbach, Jana, Scheel, Andreas H., Pamuk, Aylin, Rueschoff, Josef, Zander, Thomas, Buettner, Reinhard, Schroeder, Wolfgang, Bruns, Christiane J., Loeser, Heike, Alakus, Hakan and Quaas, Alexander (2021). Optimized PD-L1 scoring of gastric cancer. Gastric Cancer, 24 (5). S. 1115 - 1123. NEW YORK: SPRINGER. ISSN 1436-3305

Wennhold, Kerstin, Thelen, Martin ORCID: 0000-0002-2785-9726, Lehmann, Jonas, Schran, Simon, Preugszat, Ella, Garcia-Marquez, Maria, Lechner, Axel, Shimabukuro-Vornhagen, Alexander, Ercanoglu, Meryem S., Klein, Florian, Thangarajah, Fabinshy, Eidt, Sebastian, Loeser, Heike, Bruns, Christiane, Quaas, Alexander, von Bergwelt-Baildon, Michael and Schloesser, Hans A. (2021). CD86(+) Antigen-Presenting B Cells Are Increased in Cancer, Localize in Tertiary Lymphoid Structures, and Induce Specific T-cell Responses. Cancer Immunol. Res., 9 (9). S. 1098 - 1109. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2326-6074

2020

Essakly, Ahlem, Loeser, Heike, Kraemer, Max, Alakus, Hakan, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Zander, Thomas, Buettner, Reinhard, Hillmer, Axel M., Bruns, Christiane J., Schroeder, Wolfgang, Gebauer, Florian and Quaas, Alexander (2020). PIK3CA and KRAS Amplification in Esophageal Adenocarcinoma and their Impact on the Inflammatory Tumor Microenvironment and Prognosis. Transl. Oncol., 13 (2). S. 157 - 165. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1936-5233

Gebauer, Florian, Kraemer, Max, Bruns, Christiane, Schloesser, Hans A., Thelen, Martin ORCID: 0000-0002-2785-9726, Lohneis, Philipp, Schroeder, Wolfgang, Zander, Thomas, Alakus, Hakan, Buettner, Reinhard, Loeser, Heike and Quaas, Alexander (2020). Lymphocyte activation gene-3 (LAG3) mRNA and protein expression on tumour infiltrating lymphocytes (TILs) in oesophageal adenocarcinoma. J. Cancer Res. Clin. Oncol., 146 (9). S. 2319 - 2328. NEW YORK: SPRINGER. ISSN 1432-1335

Kraemer, Max, Plum, Patrick S. ORCID: 0000-0002-8165-4553, Camacho, Oscar Velazquez, Folz-Donahue, Kat, Thelen, Martin ORCID: 0000-0002-2785-9726, Garcia-Marquez, Isabel, Woelwer, Christina, Buesker, Soeren, Wittig, Jana, Franitza, Marek, Altmueller, Janine, Loeser, Heike, Schloesser, Hans, Buettner, Reinhard, Schroeder, Wolfgang, Bruns, Christiane J., Alakus, Hakan, Quaas, Alexander, Chon, Seung-Hun ORCID: 0000-0002-8923-6428 and Hillmer, Axel M. (2020). Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics. Mol. Oncol., 14 (6). S. 1170 - 1185. HOBOKEN: WILEY. ISSN 1878-0261

Loeser, Heike ORCID: 0000-0003-4555-1327, Kraemer, Max, Gebauer, Florian, Bruns, Christiane, Schroder, Wolfgang, Zander, Thomas, Alakus, Hakan, Hoelscher, Arnulf, Buettner, Reinhard, Lohneis, Philipp and Quaas, Alexander (2020). Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma. J Immunol. Res., 2020. LONDON: HINDAWI LTD. ISSN 2314-7156

Loeser, Heike ORCID: 0000-0003-4555-1327, Woelwer, Christina B., Alakus, Hakan ORCID: 0000-0002-3889-3276, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Zander, Thomas, Buettner, Reinhard, Hillmer, Axel M., Bruns, Christiane J., Schroeder, Wolfgang, Gebauer, Florian ORCID: 0000-0001-5312-4814 and Quaas, Alexander (2020). Y Chromosome Loss Is a Frequent Event in Barrett's Adenocarcinoma and Associated with Poor Outcome. Cancers, 12 (7). BASEL: MDPI. ISSN 2072-6694

Moentenich, Valeska, Comut, Erdem, Gebauer, Florian, Tuchscherer, Armin, Bruns, Christiane, Schroeder, Wolfgang, Buettner, Reinhard, Alakus, Hakan, Loeser, Heike, Zander, Thomas and Quaas, Alexander (2020). Mesothelin expression in esophageal adenocarcinoma and squamous cell carcinoma and its possible impact on future treatment strategies. Ther. Adv. Med. Oncol., 12. LONDON: SAGE PUBLICATIONS LTD. ISSN 1758-8359

Moentenich, Valeska, Gebauer, Florian, Comut, Erdem, Tuchscherer, Armin, Bruns, Christiane, Schroeder, Wolfgang, Buettner, Reinhard, Alakus, Hakan, Loeser, Heike, Zander, Thomas and Quaas, Alexander (2020). Claudin 18.2 expression in esophageal adenocarcinoma and its potential impact on future treatment strategies. Oncol. Lett., 19 (6). S. 3665 - 3671. ATHENS: SPANDIDOS PUBL LTD. ISSN 1792-1082

Rehkaemper, Jan, Korenkov, Michael, Quaas, Alexander, Rueschoff, Josef, Pamuk, Aylin, Zander, Thomas, Hillmer, Axel M., Buettner, Reinhard, Hoelscher, Arnulf Heinrich, Bruns, Christiane Josephine, Loeser, Heike, Alakus, Hakan and Schoemig-Markiefka, Birgid (2020). Amplification of KRAS and its heterogeneity in non-Asian gastric adenocarcinomas. BMC Cancer, 20 (1). LONDON: BMC. ISSN 1471-2407

Rokohl, Alexander C., Loeser, Heike, Mor, Joel M., Loreck, Niklas, Koch, Konrad R. and Heindl, Ludwig M. (2020). Young male patient with unusual space-occupying lesion of the lower eyelid. Ophthalmologe, 117 (1). S. 73 - 78. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0423

Schallenberg, Simon, Bork, Julian, Essakly, Ahlem, Alakus, Hakan, Buettner, Reinhard, Hillmer, Axel M., Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Loeser, Heike, Gebauer, Florian and Quaas, Alexander (2020). Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma. BMC Cancer, 20 (1). LONDON: BMC. ISSN 1471-2407

Schiffmann, Lars M., Loeser, Heike ORCID: 0000-0003-4555-1327, Jacob, Anne Sophie, Maus, Martin, Fuchs, Hans, Zhao, Yue, Tharun, Lars, Essakly, Ahlem, Damanakis, Alexander Iannos, Zander, Thomas, Buettner, Reinhard, Schroeder, Wolfgang, Bruns, Christiane, Quaas, Alexander and Gebauer, Florian (2020). Dickkopf-2 (DKK2) as Context Dependent Factor in Patients with Esophageal Adenocarcinoma. Cancers, 12 (2). BASEL: MDPI. ISSN 2072-6694

Wagener-Ryczek, Svenja, Schoemmel, Max, Kraemer, Max, Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Gebauer, Florian, Alakus, Hakan, Merkelbach-Bruse, Sabine, Buettner, Reinhard, Loeser, Heike, Thelen, Martin ORCID: 0000-0002-2785-9726, Schlosser, Hans A. and Quaas, Alexander (2020). Immune profile and immunosurveillance in treatment-naive and neoadjuvantly treated esophageal adenocarcinoma. Cancer Immunol. Immunother., 69 (4). S. 523 - 534. NEW YORK: SPRINGER. ISSN 1432-0851

2019

Loeser, Heike ORCID: 0000-0003-4555-1327, Kraemer, Max, Gebauer, Florian, Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Persa, Oana-Diana, Alakus, Hakan, Hoelscher, Arnulf, Buettner, Reinhard, Lohneis, Philipp and Quaas, Alexander (2019). The expression of the immune checkpoint regulator VISTA correlates with improved overall survival in pT1/2 tumor stages in esophageal adenocarcinoma. OncoImmunology, 8 (5). PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X

Plum, Patrick Sven, Gebauer, Florian, Kraemer, Max, Alakus, Hakan, Berlth, Felix, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Schiffmann, Lars, Zander, Thomas, Buettner, Reinhard, Hoelscher, Arnulf Heinrich, Bruns, Christiane Josephine, Quaas, Alexander and Loeser, Heike (2019). HER2/neu (ERBB2) expression and gene amplification correlates with better survival in esophageal adenocarcinoma. BMC Cancer, 19. LONDON: BMC. ISSN 1471-2407

Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike ORCID: 0000-0003-4555-1327, Buettner, Reinhard, Hillmer, Axel ORCID: 0000-0002-3381-7266, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas and Frommolt, Peter ORCID: 0000-0002-1966-8014 (2019). Genomic Characterization of TP53-Wild-Type Esophageal Carcinoma. Transl. Oncol., 12 (1). S. 154 - 162. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1936-5233

Schiffmann, Lars M., Goebel, Heike, Loeser, Heike, Schorn, Fabian, Werthenbach, Jan Paul, Fuchs, Hans F., Plum, Patrick S. ORCID: 0000-0002-8165-4553, Bludau, Marc, Zander, Thomas, Schroeder, Wolfgang, Bruns, Christiane J., Kashkar, Hamid, Quaas, Alexander and Gebauer, Florian (2019). Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma. BMC Cancer, 19. LONDON: BMC. ISSN 1471-2407

2018

Buchner, Denise, Hieggelke, Lena, Loeser, Heike, Bruns, Christiane Josephine, Quaas, Alexander and Ghadimi, Markus Philipp Hussein (2018). First reported case of a collision tumor composed of pancreatic adenocarcinoma and retroperitoneal liposarcoma: a case report. BMC Cancer, 18. LONDON: BMC. ISSN 1471-2407

Kasper, Philipp, Loeser, Heike and Goeser, Tobias (2018). Varioliform gastritis: an unusual endoscopic finding. Ann. Gastroenterol., 31 (4). S. 519 - 520. ATHENS: HELLENIC SOC GASTROENTEROLOGY. ISSN 1792-7463

Plum, Patrick Sven, Ulase, Dita, Bollschweiler, Elfriede, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Berlth, Felix, Zander, Thomas, Alakus, Hakan, Hoelscher, Arnulf H., Bruns, Christiane J., Schallenberg, Simon, Quaas, Alexander and Loeser, Heike (2018). Upregulation of insulin-like growth factor II mRNA-binding protein 3 (IMP3) has negative prognostic impact on early invasive (pT1) adenocarcinoma of the esophagus. J. Cancer Res. Clin. Oncol., 144 (9). S. 1731 - 1740. NEW YORK: SPRINGER. ISSN 1432-1335

2017

Loeser, Heike, Schallenberg, Simon, von Winterfeld, Moritz, Tharun, Lars, Alakus, Hakan, Hoelscher, Arnulf, Bollschweiler, Elfriede, Buettner, Reinhard, Zander, Thomas and Quaas, Alexander (2017). High protein and mRNA expression levels of TUBB3 (class III beta-tubulin) are associated with aggressive tumor features in esophageal adenocarcinomas. Oncotarget, 8 (70). S. 115179 - 115190. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Loeser, Heike, Waldschmidt, Dirk, Kuetting, Fabian, Heydt, Carina, Zander, Thomas, Plum, Patrick, Alakus, Hakan, Buettner, Reinhard and Quaas, Alexander (2017). Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target. Mol. Clin. Oncol., 6 (5). S. 639 - 643. ATHENS: SPANDIDOS PUBL LTD. ISSN 2049-9469

Loeser, Heike, Waldschmidt, Dirk, Kuetting, Fabian, Schallenberg, Simon, Zander, Thomas, Bollschweiler, Elfriede, Hoelscher, Arnulf, Weckermann, Katharina, Plum, Patrick, Alakus, Hakan, Buettner, Reinhard and Quaas, Alexander (2017). Somatic BRCA1-associated protein 1 (BAP1) loss is an early and rare event in esophageal adenocarcinoma. Mol. Clin. Oncol., 7 (2). S. 225 - 229. ATHENS: SPANDIDOS PUBL LTD. ISSN 2049-9469

2015

Loeser, Heike, von Brandenstein, Melanie, Herschung, Angela, Schlosser, Monika, Buettner, Reinhard and Fries, Jochen W. U. (2015). ET-1 Induced Downregulation of MRP2 via miRNA 133a-A Marker for Tubular Nephrotoxicity? Am. J. Nephrol., 41 (3). S. 191 - 200. BASEL: KARGER. ISSN 1421-9670

von Brandenstein, Melanie, Puetz, Katharina, Schlosser, Monika, Loeser, Heike, Kallinowski, Joachim P., Goedde, Daniel, Buettner, Reinhard, Stoerkel, Stefan and Fries, Jochen W. U. (2015). Vimentin 3, the New Hope, Differentiating RCC versus Oncocytoma. Dis. Markers, 2015. LONDON: HINDAWI LTD. ISSN 1875-8630