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2022
Offermann, Anne, Joerg, Vincent, Becker, Finn, Roesch, Marie C., Kang, Duan, Lemster, Anna-Lena, Tharun, Lars, Behrends, Jochen ORCID: 0000-0002-0648-8911, Merseburger, Axel S., Culig, Zoran, Sailer, Verena, Braegelmann, Johannes, Kirfel, Jutta and Perner, Sven
(2022).
Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.
Am. J. Pathol., 192 (5).
S. 813 - 824.
NEW YORK:
ELSEVIER SCIENCE INC.
ISSN 1525-2191
2021
Offermann, Anne, Joerg, Vincent, Hupe, Marie C., Becker, Finn, Mueller, Marten, Braegelmann, Johannes, Kirfel, Jutta, Merseburger, Axel S., Sailer, Verena, Tharun, Lars and Perner, Sven (2021). CDK19 as a diagnostic marker for high-grade prostatic intraepithelial neoplasia. Hum. Pathol., 117. S. 60 - 68. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1532-8392
Watermann, Christian ORCID: 0000-0002-6960-5863, Pasternack, Helen
ORCID: 0000-0003-2386-2300, Idel, Christian, Ribbat-Idel, Julika, Braegelmann, Johannes, Kuppler, Patrick, Offermann, Anne, Jonigk, Danny, Kuehnel, Mark, Schroeck, Andreas, Dreyer, Eva, Rosero, Christian, Nathansen, Jacqueline, Dubrovska, Anna, Tharun, Lars, Kirfel, Jutta, Wollenberg, Barbara, Perner, Sven and Krupar, Rosemarie
(2021).
Recurrent HNSCC Harbor an Immunosuppressive Tumor Immune Microenvironment Suggesting Successful Tumor Immune Evasion.
Clin. Cancer Res., 27 (2).
S. 632 - 645.
PHILADELPHIA:
AMER ASSOC CANCER RESEARCH.
ISSN 1557-3265
2020
Schiffmann, Lars M., Loeser, Heike ORCID: 0000-0003-4555-1327, Jacob, Anne Sophie, Maus, Martin, Fuchs, Hans, Zhao, Yue, Tharun, Lars, Essakly, Ahlem, Damanakis, Alexander Iannos, Zander, Thomas, Buettner, Reinhard, Schroeder, Wolfgang, Bruns, Christiane, Quaas, Alexander and Gebauer, Florian
(2020).
Dickkopf-2 (DKK2) as Context Dependent Factor in Patients with Esophageal Adenocarcinoma.
Cancers, 12 (2).
BASEL:
MDPI.
ISSN 2072-6694
Shostak, Kateryna, Jiang, Zheshen, Charloteaux, Benoit, Mayer, Alice, Habraken, Yvette, Tharun, Lars, Klein, Sebastian ORCID: 0000-0002-2188-9377, Xu, Xinyi, Vislovukh, Andrii, Close, Pierre, Florin, Alexandra, Rambow, Florian, Marine, Jean-Christophe
ORCID: 0000-0003-2433-9837, Buettner, Reinhard and Chariot, Alain
(2020).
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage.
Nat. Commun., 11 (1).
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2041-1723
2018
Fischer, Janina, Simon, Thorsten, Hamprecht, Axel ORCID: 0000-0003-1449-5780, Hos, Nina, Moericke, Anja, Cernaianu, Grigore, Tharun, Lars, Gruhn, Bernd, Plum, Georg and Duebbers, Martin
(2018).
Surgical Implications for Diagnosis and Treatment of Intestinal Aspergillosis in Pediatric Patients with ALL.
Eur. J. Pediatr. Surg., 28 (6).
S. 477 - 484.
STUTTGART:
GEORG THIEME VERLAG KG.
ISSN 1439-359X
Golfmann, Kristina, Meder, Lydia ORCID: 0000-0002-9547-5812, Koker, Mirjam, Volz, Caroline, Borchmann, Sven, Tharun, Lars, Dietlein, Felix, Malchers, Florian, Florin, Alexandra, Buettner, Reinhard, Rosen, Neal, Rodrik-Outmezguine, Vanessa, Hallek, Michael and Ullrich, Roland T.
(2018).
Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer.
Oncogene, 37 (42).
S. 5682 - 5694.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 1476-5594
Nemazanyy, Ivan, Rambow, Florian, Tang, Seng Chuan, Delaunay, Sylvain, Tharun, Lars, Florin, Alexandra, Buttner, Reinhard, Vandaele, Daniel, Close, Pierre, Marine, Jean-Christophe ORCID: 0000-0003-2433-9837, Shostak, Kateryna and Chariot, Alain
(2018).
The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.
Cancer Res., 78 (16).
S. 4533 - 4549.
PHILADELPHIA:
AMER ASSOC CANCER RESEARCH.
ISSN 1538-7445
Rapino, Francesca ORCID: 0000-0002-4343-3805, Delaunay, Sylvain, Rambow, Florian, Zhou, Zhaoli, Tharun, Lars, De Tullio, Pascal, Sin, Olga
ORCID: 0000-0002-0976-0570, Shostak, Kateryna, Schmitz, Sebastian, Piepers, Jolanda, Ghesquiere, Bart
ORCID: 0000-0003-1547-1705, Karim, Latifa, Charloteaux, Benoit, Jamart, Diane, Florin, Alexandra, Lambert, Charles, Rorive, Andree, Jerusalem, Guy, Leucci, Eleonora
ORCID: 0000-0002-2898-748X, Dewaele, Michael, Vooijs, Marc, Leidel, Sebastian A., Georges, Michel, Voz, Marianne, Peers, Bernard, Buettner, Reinhard, Marine, Jean-Christophe
ORCID: 0000-0003-2433-9837, Chariot, Alain and Close, Pierre
(2018).
Codon-specific translation reprogramming promotes resistance to targeted therapy.
Nature, 558 (7711).
S. 605 - 636.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 1476-4687
Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo
ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta
ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis
ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian
(2018).
The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression.
Cell Reports, 25 (4).
S. 1027 - 1046.
CAMBRIDGE:
CELL PRESS.
ISSN 2211-1247
2017
Koelsche, Christian ORCID: 0000-0001-8763-8864, Schrimpf, Daniel, Tharun, Lars, Roth, Eva, Sturm, Dominik
ORCID: 0000-0003-0250-1696, Jones, David T. W., Renker, Eva-Kristin, Sill, Martin, Baude, Annika, Sahm, Felix
ORCID: 0000-0001-5441-1962, Capper, David
ORCID: 0000-0003-1945-497X, Bewerunge-Hudler, Melanie, Hartmann, Wolfgang
ORCID: 0000-0002-7609-5021, Kulozik, Andreas E., Petersen, Iver, Flucke, Uta, Schreuder, Hendrik W. B., Buettner, Reinhard, Weber, Marc-Andre, Schirmacher, Peter, Plass, Christoph, Pfister, Stefan M., von Deimling, Andreas
ORCID: 0000-0002-5863-540X and Mechtersheimer, Gunhild
(2017).
Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases.
Clin. Sarcoma Res., 7.
LONDON:
BMC.
ISSN 2045-3329
Lechner, Axel, Schloesser, Hans, Rothschild, Sacha I., Thelen, Martin ORCID: 0000-0002-2785-9726, Reuter, Sabrina, Zentis, Peter, Shimabukuro-Vornhagen, Alexander, Theurich, Sebastian
ORCID: 0000-0001-5706-8258, Wennhold, Kerstin
ORCID: 0000-0001-5539-7226, Garcia-Marquez, Maria, Tharun, Lars, Quaas, Alexander, Schauss, Astrid, Isensee, Joerg
ORCID: 0000-0002-3390-0051, Hucho, Tim
ORCID: 0000-0002-4147-9308, Huebbers, Christian
ORCID: 0000-0002-2934-1218, von Bergwelt-Baildon, Michael and Beutner, Dirk
(2017).
Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma.
Oncotarget, 8 (27).
S. 44418 - 44434.
ORCHARD PARK:
IMPACT JOURNALS LLC.
ISSN 1949-2553
Loeser, Heike, Schallenberg, Simon, von Winterfeld, Moritz, Tharun, Lars, Alakus, Hakan, Hoelscher, Arnulf, Bollschweiler, Elfriede, Buettner, Reinhard, Zander, Thomas and Quaas, Alexander (2017). High protein and mRNA expression levels of TUBB3 (class III beta-tubulin) are associated with aggressive tumor features in esophageal adenocarcinomas. Oncotarget, 8 (70). S. 115179 - 115190. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553
2016
Delaunay, Sylvain, Rapino, Francesca ORCID: 0000-0002-4343-3805, Tharun, Lars, Zhou, Zhaoli, Heukamp, Lukas
ORCID: 0000-0002-3388-3482, Termathe, Martin
ORCID: 0000-0002-5618-4633, Shostak, Kateryna, Klevernic, Iva, Florin, Alexandra, Desmecht, Hadrien, Desmet, Christophe J., Nguyen, Laurent
ORCID: 0000-0002-8560-3008, Leidel, Sebastian A., Willis, Anne E., Buettner, Reinhard, Chariot, Alain and Close, Pierre
(2016).
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.
J. Exp. Med., 213 (11).
S. 2503 - 2524.
NEW YORK:
ROCKEFELLER UNIV PRESS.
ISSN 1540-9538
Tharun, Lars, Scheel, Andreas H., Zander, Thomas, Alakus, Hakan, Buettner, Reinhard and Quaas, Alexander (2016). PD-L1 status in esophageal carcinoma at the mRNA and protein level. J. Clin. Oncol., 34 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755
Tharun, Lars, Steuer, Stefan and Quaas, Alexander (2016). Role of pathologists with respect to therapy decisions for gastric cancer. Onkologe, 22 (6). S. 400 - 406. NEW YORK: SPRINGER. ISSN 1433-0415
Walch-Rueckheim, Barbara, Pahne-Zeppenfeld, Jennifer, Fischbach, Jil, Wickenhauser, Claudia, Horn, Lars Christian, Tharun, Lars, Buettner, Reinhard, Mallmann, Peter, Stern, Peter, Kim, Yoo-Jin, Bohle, Rainer Maria, Ruebe, Christian, Stroeder, Russalina, Juhasz-Boess, Ingolf, Solomayer, Erich-Franz and Smola, Sigrun (2016). STAT3/IRF1 Pathway Activation Sensitizes Cervical Cancer Cells to Chemotherapeutic Drugs. Cancer Res., 76 (13). S. 3872 - 3884. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445
2015
Dietlein, Felix, Kalb, Bastian, Jokic, Mladen, Noll, Elisa M., Strong, Alexander, Tharun, Lars, Ozretic, Luka, Kuenstlinger, Helen, Kambartel, Kato, Randerath, Winfried J., Juengst, Christian, Schmitt, Anna, Torgovnick, Alessandro, Richters, Andre, Rauh, Daniel ORCID: 0000-0002-1970-7642, Siedek, Florian, Persigehl, Thorsten, Mauch, Cornelia, Bartkova, Jirina, Bradley, Allan
ORCID: 0000-0002-2349-8839, Sprick, Martin R.
ORCID: 0000-0001-9691-7574, Trumpp, Andreas
ORCID: 0000-0002-6212-3466, Rad, Roland, Saur, Dieter
ORCID: 0000-0001-5874-0210, Bartek, Jiri, Wolf, Juergen, Buettner, Reinhard, Thomas, Roman K. and Reinhardt, H. Christian
(2015).
A Synergistic Interaction between Chk1-and MK2 Inhibitors in KRAS-Mutant Cancer.
Cell, 162 (1).
S. 146 - 160.
CAMBRIDGE:
CELL PRESS.
ISSN 1097-4172
Ladang, Aurelie, Rapino, Francesca ORCID: 0000-0002-4343-3805, Heukamp, Lukas C., Tharun, Lars, Shostak, Kateryna, Hermand, Damien, Delaunay, Sylvain
ORCID: 0000-0003-1077-829X, Klevernic, Iva, Jiang, Zheshen
ORCID: 0000-0002-4914-7041, Jacques, Nicolas, Jamart, Diane, Migeot, Valerie, Florin, Alexandra, Goktuna, Serkan
ORCID: 0000-0001-6169-768X, Malgrange, Brigitte, Sansom, Owen J.
ORCID: 0000-0001-9540-3010, Nguyen, Laurent
ORCID: 0000-0002-8560-3008, Buettner, Reinhard, Close, Pierre and Chariot, Alain
(2015).
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.
J. Exp. Med., 212 (12).
S. 2057 - 2076.
NEW YORK:
ROCKEFELLER UNIV PRESS.
ISSN 1540-9538
Ortiz-Cuaran, Sandra, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Lovly, Christine M., Bos, Marc, Scheffler, Matthias, Michels, Sebastian, Albus, Kerstin, Meyer, Lydia, Koenig, Katharina, Dahmen, Ilona, Mueller, Christian, Ozretic, Luca, Tharun, Lars, Schaub, Philipp, Florin, Alexandra, Pinther, Berit, Bahlmann, Nike, Ansen, Sascha, Peifer, Martin, Heukamp, Lukas C., Buettner, Reinhard, Sos, Martin L., Wolf, Juergen, Pao, William and Thomas, Roman K.
(2015).
Elucidating the mechanisms of acquired resistance in lung adenocarcinomas.
Cancer Res., 75.
PHILADELPHIA:
AMER ASSOC CANCER RESEARCH.
ISSN 1538-7445
Schulze, Kornelius, Weismueller, Tobias J., Bubenheim, Michael, Huebener, Peter ORCID: 0000-0001-7558-7625, Zenouzi, Roman, Lenzen, Henrike, Rupp, Christian, Gotthardt, Daniel, de Leuw, Philipp, Teufel, Andreas, Zimmer, Vincent
ORCID: 0000-0002-6298-4717, Reiter, Florian P., Rust, Christian, Tharun, Lars, Quaas, Alexander, Weidemann, Soern A., Lammert, Frank, Sarrazin, Christoph, Manns, Michael P., Lohse, Ansgar W. and Schramm, Christoph
ORCID: 0000-0002-4264-1928
(2015).
Criteria Used in Clinical Practice to Guide Immunosuppressive Treatment in Patients with Primary Sclerosing Cholangitis.
PLoS One, 10 (10).
SAN FRANCISCO:
PUBLIC LIBRARY SCIENCE.
ISSN 1932-6203