Universität zu Köln

Ackermann, Sandra ORCID: 0000-0002-5869-7344, Cartolano, Maria, Hero, Barbara, Welte, Anne, Kahlert, Yvonne, Roderwieser, Andrea, Bartenhagen, Christoph, Walter, Esther, Gecht, Judith, Kerschke, Laura, Volland, Ruth, Menon, Roopika, Heuckmann, Johannes M., Gartlgruber, Moritz, Hartlieb, Sabine ORCID: 0000-0003-3746-7010, Henrich, Kai-Oliver, Okonechnikov, Konstantin, Altmueller, Janine, Nuernberg, Peter, Lefever, Steve, de Wilde, Bram, Sand, Frederik, Ikram, Fakhera, Rosswog, Carolina, Fischer, Janina, Theissen, Jessica, Hertwig, Falk ORCID: 0000-0003-4784-6516, Singhi, Aatur D., Simon, Thorsten, Vogel, Wenzel, Perner, Sven, Krug, Barbara, Schmidt, Matthias, Rahmann, Sven, Achter, Viktor, Lang, Ulrich ORCID: 0000-0001-7166-0805, Vokuhl, Christian, Ortmann, Monika, Buettner, Reinhard, Eggert, Angelika, Speleman, Frank, O'Sullivan, Roderick J., Thomas, Roman K., Berthold, Frank, Vandesompele, Jo, Schramm, Alexander, Westermann, Frank, Schulte, Johannes H., Peifer, Martin and Fischer, Matthias (2018). A mechanistic classification of clinical phenotypes in neuroblastoma. Science, 362 (6419). S. 1165 - 1205. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

Alborzinia, Hamed, Florez, Andres F., Kreth, Sina, Brueckner, Lena M., Yildiz, Umut ORCID: 0000-0002-7175-362X, Gartlgruber, Moritz, Odoni, Dorett, I, Poschet, Gernot ORCID: 0000-0002-5344-0865, Garbowicz, Karolina, Shao, Chunxuan, Klein, Corinna, Meier, Jasmin, Zeisberger, Petra, Nadler-Holly, Michal, Ziehm, Matthias ORCID: 0000-0001-7074-4054, Paul, Franziska, Burhenne, Juergen, Bell, Emma, Shaikhkarami, Marjan, Wuerth, Roberto, Stainczyk, Sabine A., Wecht, Elisa M., Kreth, Jochen, Buettner, Michael, Ishaque, Naveed ORCID: 0000-0002-8426-901X, Schlesner, Matthias, Nicke, Barbara, Stresemann, Carlo, Llamazares-Prada, Maria, Reiling, Jan H., Fischer, Matthias, Amit, Ido, Selbach, Matthias ORCID: 0000-0003-2454-8751, Herrmann, Carl, Woelfl, Stefan, Henrich, Kai-Oliver, Hoefer, Thomas, Trumpp, Andreas and Westermann, Frank (2022). MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis. Nat. Cancer, 3 (4). S. 471 - 502. BERLIN: NATURE PORTFOLIO. ISSN 2662-1347

Dreidax, Daniel, Bannert, Steffen, Henrich, Kai-Oliver, Schroeder, Christina, Bender, Sebastian, Oakes, Christopher C., Lindner, Sven, Schulte, Johannes H., Duffy, David ORCID: 0000-0002-6075-8855, Schwarzl, Thomas ORCID: 0000-0001-7697-7000, Saadati, Maral, Ehemann, Volker, Benner, Axel, Pfister, Stefan, Fischer, Matthias and Westermann, Frank (2014). p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas. Hum. Mol. Genet., 23 (25). S. 6826 - 6838. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Duffy, David J., Krstic, Aleksandar ORCID: 0000-0002-7128-5707, Halasz, Melinda ORCID: 0000-0002-6175-9630, Schwarzl, Thomas ORCID: 0000-0001-7697-7000, Fey, Dirk ORCID: 0000-0002-5558-0167, Iljin, Kristiina, Mehta, Jai Prakash, Killick, Kate, Whilde, Jenny, Turriziani, Benedetta, Haapa-Paananen, Saija, Fey, Vidal, Fischer, Matthias, Westermann, Frank, Henrich, Kai-Oliver, Bannert, Steffen, Higgins, Desmond G. and Kolch, Walter ORCID: 0000-0001-5777-5016 (2015). Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma. Oncotarget, 6 (41). S. 43182 - 43202. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Duffy, David J., Krstic, Aleksandar, Schwarzl, Thomas ORCID: 0000-0001-7697-7000, Halasz, Melinda ORCID: 0000-0002-6175-9630, Iljin, Kristiina, Fey, Dirk ORCID: 0000-0002-5558-0167, Haley, Bridget, Whilde, Jenny, Haapa-Paananen, Saija, Fey, Vidal, Fischer, Matthias, Westermann, Frank, Henrich, Kai-Oliver, Bannert, Steffen, Higgins, Desmond G. and Kolch, Walter (2016). Wnt signalling is a bi-directional vulnerability of cancer cells. Oncotarget, 7 (37). S. 60310 - 60332. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Fabian, Johannes, Lodrini, Marco, Oehme, Ina, Schier, Marie C., Thole, Theresa M., Hielscher, Thomas, Kopp-Schneider, Annette ORCID: 0000-0002-1810-0267, Opitz, Lennart, Capper, David ORCID: 0000-0003-1945-497X, von Deimling, Andreas ORCID: 0000-0002-5863-540X, Wiegand, Inga, Milde, Till ORCID: 0000-0002-7267-1052, Mahlknecht, Ulrich, Westermann, Frank, Popanda, Odilia, Roels, Frederik, Hero, Barbara, Berthold, Frank, Fischer, Matthias, Kulozik, Andreas E., Witt, Olaf and Deubzer, Hedwig E. (2014). GRHL1 Acts as Tumor Suppressor in Neuroblastoma and Is Negatively Regulated by MYCN and HDAC3. Cancer Res., 74 (9). S. 2604 - 2617. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Fey, Dirk ORCID: 0000-0002-5558-0167, Halasz, Melinda ORCID: 0000-0002-6175-9630, Dreidax, Daniel, Kennedy, Sean P., Hastings, Jordan F., Rauch, Nora ORCID: 0000-0001-6009-5177, Munoz, Amaya Garcia, Pilkington, Ruth, Fischer, Matthias, Westermann, Frank, Kolch, Walter ORCID: 0000-0001-5777-5016, Kholodenko, Boris N. and Croucher, David R. (2015). Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients. Sci. Signal., 8 (408). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1937-9145

Groebner, Susanne N., Worst, Barbara C., Weischenfeldt, Joachim ORCID: 0000-0002-3917-5524, Buchhalter, Ivo ORCID: 0000-0003-0764-5832, Kleinheinz, Kortine, Rudneva, Vasilisa A., Johann, Pascal D., Balasubramanian, Gnana Prakash, Segura-Wang, Maia ORCID: 0000-0003-2424-618X, Brabetz, Sebastian, Bender, Sebastian, Hutter, Barbara, Sturm, Dominik ORCID: 0000-0003-0250-1696, Pfaff, Elke, Huebschmann, Daniel ORCID: 0000-0002-6041-7049, Zipprich, Gideon, Heinold, Michael, Eils, Jurgen, Lawerenz, Christian, Erkek, Serap ORCID: 0000-0003-4439-5203, Lambo, Sander, Waszak, Sebastian ORCID: 0000-0003-3042-9521, Blattmann, Claudia, Borkhardt, Arndt, Kuhlen, Michaela, Eggert, Angelika, Fulda, Simone ORCID: 0000-0002-0459-6417, Gessler, Manfred ORCID: 0000-0002-7915-6045, Wegert, Jenny, Kappler, Roland ORCID: 0000-0002-8581-2803, Baumhoer, Daniel, Burdach, Stefan, Kirschner-Schwabe, Renate ORCID: 0000-0001-6335-3274, Kontny, Udo, Kulozik, Andreas E., Lohmann, Dietmar, Hettmer, Simone, Eckert, Cornelia, Bielack, Stefan, Nathrath, Michaela, Niemeyer, Charlotte, Richter, Gunther H., Schulte, Johannes, Siebert, Reiner, Westermann, Frank, Molenaar, Jan J., Vassal, Gilles, Witt, Hendrik, Burkhardt, Birgit, Kratz, Christian P., Witt, Olaf, van Tilburg, Cornelis M., Kramm, Christof M., Fleischhack, Gudrun, Dirksen, Uta, Rutkowski, Stefan, Fruhwald, Michael, von Hoff, Katja, Wolf, Stephan, Klingebiel, Thomas, Koscielniak, Ewa, Landgraf, Pablo, Koster, Jan ORCID: 0000-0002-0890-7585, Resnick, Adam C., Zhang, Jinghui, Liu, Yanling, Zhou, Xin, Waanders, Angela J., Zwijnenburg, Danny A., Raman, Pichai, Brors, Benedikt ORCID: 0000-0001-5940-3101, Weber, Ursula D., Northcott, Paul A., Pajtler, Kristian W. ORCID: 0000-0002-3562-6121, Kool, Marcel, Piro, Rosario M. ORCID: 0000-0002-3066-7397, Korbel, Jan O., Schlesner, Matthias ORCID: 0000-0002-5896-4086, Eils, Roland ORCID: 0000-0002-0034-4036, Jones, David T. W., Lichter, Peter, Chavez, Lukas ORCID: 0000-0002-8718-8848, Zapatka, Marc ORCID: 0000-0001-8287-5967 and Pfister, Stefan M. (2018). The landscape of genomic alterations across childhood cancers. Nature, 555 (7696). S. 321 - 344. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Hartlieb, Sabine A., Sieverling, Lina, Nadler-Holly, Michal, Ziehm, Matthias ORCID: 0000-0001-7074-4054, Toprak, Umut H., Herrmann, Carl ORCID: 0000-0003-4989-4722, Ishaque, Naveed ORCID: 0000-0002-8426-901X, Okonechnikov, Konstantin, Gartlgruber, Moritz, Park, Young-Gyu, Wecht, Elisa Maria, Savelyeva, Larissa, Henrich, Kai-Oliver, Rosswog, Carolina, Fischer, Matthias, Hero, Barbara, Jones, David T. W., Pfaff, Elke, Witt, Olaf, Pfister, Stefan M., Volckmann, Richard, Koster, Jan, Kiesel, Katharina, Rippe, Karsten ORCID: 0000-0001-9951-9395, Taschner-Mandl, Sabine ORCID: 0000-0002-1439-5301, Ambros, Peter, Brors, Benedikt ORCID: 0000-0001-5940-3101, Selbach, Matthias, Feuerbach, Lars and Westermann, Frank (2021). Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome. Nat. Commun., 12 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723

Henrich, Kai-Oliver, Bender, Sebastian, Saadati, Maral, Dreidax, Daniel, Gartlgruber, Moritz, Shao, Chunxuan, Herrmann, Carl ORCID: 0000-0003-4989-4722, Wiesenfarth, Manuel, Parzonka, Martha, Wehrmann, Lea, Fischer, Matthias, Duffy, David J., Bell, Emma, Torkov, Alica, Schmezer, Peter, Plass, Christoph, Hoefer, Thomas, Benner, Axel, Pfister, Stefan M. and Westermann, Frank (2016). Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas. Cancer Res., 76 (18). S. 5523 - 5538. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Henssen, Anton ORCID: 0000-0003-1534-778X, Althoff, Kristina, Odersky, Andrea, Beckers, Anneleen, Koche, Richard ORCID: 0000-0002-6820-5083, Speleman, Frank, Schaefers, Simon, Bell, Emma, Nortmeyer, Maike, Westermann, Frank, De Preter, Katleen, Florin, Alexandra, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Spruessel, Annika, Astrahanseff, Kathy, Lindner, Sven, Sadowski, Natalie, Schramm, Alexander ORCID: 0000-0001-7670-7529, Astorgues-Xerri, Lucile, Riveiro, Maria E., Eggert, Angelika, Cvitkovic, Esteban and Schulte, Johannes H. (2016). Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Clin. Cancer Res., 22 (10). S. 2470 - 2482. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Ikram, Fakhera ORCID: 0000-0001-7796-4746, Ackermann, Sandra ORCID: 0000-0002-5869-7344, Kahlert, Yvonne, Volland, Ruth, Roels, Frederik, Engesser, Anne, Hertwig, Falk ORCID: 0000-0003-4784-6516, Kocak, Hayriye, Hero, Barbara, Dreidax, Daniel, Henrich, Kai-Oliver, Berthold, Frank, Nuernberg, Peter, Westermann, Frank and Fischer, Matthias (2016). Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma. Mol. Oncol., 10 (2). S. 344 - 360. OXFORD: ELSEVIER SCI LTD. ISSN 1878-0261

Layer, Julian P., Kronmueller, Marie T., Quast, Thomas, van den Boorn-Konijnenberg, Debby, Effern, Maike ORCID: 0000-0002-1766-9881, Hinze, Daniel, Althoff, Kristina, Schramm, Alexander ORCID: 0000-0001-7670-7529, Westermann, Frank, Peifer, Martin ORCID: 0000-0002-5243-5503, Hartmann, Gunther ORCID: 0000-0003-1021-2018, Tueting, Thomas, Kolanus, Waldemar, Fischer, Matthias, Schulte, Johannes and Hoelzel, Michael (2017). Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression. OncoImmunology, 6 (6). PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X

Peifer, Martin ORCID: 0000-0002-5243-5503, Hertwig, Falk ORCID: 0000-0003-4784-6516, Roels, Frederik, Dreidax, Daniel, Gartlgruber, Moritz, Menon, Roopika, Kraemer, Andrea, Roncaioli, Justin L., Sand, Frederik, Heuckmann, Johannes M., Ikram, Fakhera ORCID: 0000-0001-7796-4746, Schmidt, Rene, Ackermann, Sandra, Engesser, Anne, Kahlert, Yvonne, Vogel, Wenzel, Altmueller, Janine, Nuernberg, Peter, Thierry-Mieg, Jean, Thierry-Mieg, Danielle ORCID: 0000-0001-9568-4211, Mariappan, Aruljothi, Heynck, Stefanie, Mariotti, Erika, Henrich, Kai-Oliver, Gloeckner, Christian, Bosco, Graziella, Leuschner, Ivo, Schweiger, Michal R., Savelyeva, Larissa, Watkins, Simon C., Shao, Chunxuan, Bell, Emma, Hoefer, Thomas, Achter, Viktor, Lang, Ulrich ORCID: 0000-0001-7166-0805, Theissen, Jessica, Volland, Ruth, Saadati, Maral, Eggert, Angelika ORCID: 0000-0003-3476-8184, de Wilde, Bram, Berthold, Frank, Peng, Zhiyu, Zhao, Chen, Shi, Leming, Ortmann, Monika, Buettner, Reinhard, Perner, Sven, Hero, Barbara, Schramm, Alexander, Schulte, Johannes H., Herrmann, Carl ORCID: 0000-0003-4989-4722, O'Sullivan, Roderick J., Westermann, Frank, Thomas, Roman K. and Fischer, Matthias (2015). Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature, 526 (7575). S. 700 - 705. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Peifer, Martin, Roels, Frederik, Hertwig, Falk ORCID: 0000-0003-4784-6516, Menon, Roopika, Kraemer, Andrea, Buettner, Reinhard, Perner, Sven, Schramm, Alexander, Schulte, Johannes H., Westermann, Frank, Thomas, Roman K. and Fischer, Matthias (2015). Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Cancer Res., 75. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Worst, Barbara C., van Tilburg, Cornelis M., Balasubramanian, Gnana Prakash, Fiesel, Petra, Witt, Ruth, Freitag, Angelika, Boudalil, Miream, Previti, Christopher, Wolf, Stephan, Schmidt, Sabine, Chotewutmontri, Sasithorn, Bewerunge-Hudler, Melanie, Schick, Matthias, Schlesner, Matthias ORCID: 0000-0002-5896-4086, Hutter, Barbara ORCID: 0000-0002-9034-0329, Taylor, Lenka, Borst, Tobias, Sutter, Christian, Bartram, Claus R., Milde, Till ORCID: 0000-0002-7267-1052, Pfaff, Elke, Kulozik, Andreas E., von Stackelberg, Arend, Meisel, Roland, Borkhardt, Arndt, Reinhardt, Dirk, Klusmann, Jan-Henning ORCID: 0000-0002-1070-0727, Fleischhack, Gudrun, Tippelt, Stephan, Dirksen, Uta, Juergens, Heribert, Kramm, Christof M., von Bueren, Andre O., Westermann, Frank, Fischer, Matthias, Burkhardt, Birgit, Wossmann, Wilhelm, Nathrath, Michaela, Bielack, Stefan S., Fruehwald, Michael C., Fulda, Simone ORCID: 0000-0002-0459-6417, Klingebiel, Thomas, Koscielniak, Ewa, Schwab, Matthias, Tremmel, Roman ORCID: 0000-0003-1564-0433, Driever, Pablo Hernaiz, Schulte, Johannes H., Brors, Benedikt ORCID: 0000-0001-5940-3101, von Deimling, Andreas ORCID: 0000-0002-5863-540X, Lichter, Peter, Eggert, Angelika, Capper, David ORCID: 0000-0003-1945-497X, Pfister, Stefan M., Jones, David T. W. and Witt, Olaf (2016). Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study. Eur. J. Cancer, 65. S. 91 - 102. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

van Tilburg, Cornelis M., Pfaff, Elke, Pajtler, Kristian W., Langenberg, Karin P. S., Fiesel, Petra, Jones, Barbara C., Balasubramanian, Gnana Prakash, Stark, Sebastian, Johann, Pascal D., Blattner-Johnson, Mirjam, Schramm, Kathrin, Dikow, Nicola, Hirsch, Steffen, Sutter, Christian, Grund, Kerstin, von Stackelberg, Arend, Kulozik, Andreas E., Lissat, Andrej, Borkhardt, Arndt, Meisel, Roland, Reinhardt, Dirk, Klusmann, Jan-Henning ORCID: 0000-0002-1070-0727, Fleischhack, Gudrun, Tippelt, Stephan, von Schweinitz, Dietrich, Schmid, Irene, Kramm, Christof M., von Bueren, Andre O., Calaminus, Gabriele, Vorwerk, Peter, Graf, Norbert ORCID: 0000-0002-2248-323X, Westermann, Frank, Fischer, Matthias, Eggert, Angelika ORCID: 0000-0003-3476-8184, Burkhardt, Birgit, Woessmann, Wilhelm, Nathrath, Michaela, Hecker-Nolting, Stefanie, Fruehwald, Michael C., Schneider, Dominik T. ORCID: 0000-0001-8153-1601, Brecht, Ines B., Ketteler, Petra, Fulda, Simone ORCID: 0000-0002-0459-6417, Koscielniak, Ewa, Meister, Michael T., Scheer, Monika, Hettmer, Simone, Schwab, Matthias, Tremmel, Roman, Ora, Ingrid, Hutter, Caroline, Gerber, Nicolas U., Lohi, Olli, Kazanowska, Bernarda ORCID: 0000-0002-7198-9122, Kattamis, Antonis, Filippidou, Maria, Goemans, Bianca, Zwaan, C. Michel, Milde, Till, Jaeger, Natalie, Wolf, Stephan, Reuss, David, Sahm, Felix ORCID: 0000-0001-5441-1962, von Deimling, Andreas ORCID: 0000-0002-5863-540X, Dirksen, Uta, Freitag, Angelika, Witt, Ruth, Lichter, Peter, Kopp-Schneider, Annette, Jones, David T. W., Molenaar, Jan J., Capper, David ORCID: 0000-0003-1945-497X, Pfister, Stefan M. and Witt, Olaf (2021). The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets. Cancer Discov., 11 (11). S. 2764 - 2780. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290