Universität zu Köln

Journal Article

Beckmann, Laura ORCID: 0000-0001-5207-8991, Berg, Valeska, Dickhut, Clarissa, Sun, Clare ORCID: 0000-0001-8498-4729, Merkel, Olaf, Bloehdorn, Johannes ORCID: 0000-0003-1433-9702, Robrecht, Sandra, Seifert, Marc, Guerreiro, Alexandra da Palma, Claasen, Julia, Loroch, Stefan, Oliverio, Matteo, Underbayev, Chingiz, Vaughn, Lauren, Thomalla, Daniel, Huelsemann, Malte F., Tausch, Eugen, Fischer, Kirsten, Fink, Anna Maria ORCID: 0000-0002-7669-7890, Eichhorst, Barbara, Sickmann, Albert ORCID: 0000-0002-2388-5265, Wendtner, Clemens M., Stilgenbauer, Stephan, Hallek, Michael, Wiestner, Adrian, Zahedi, Rene P. and Frenzel, Lukas P. (2021). MARCKS affects cell motility and response to BTK inhibitors in CLL. Blood, 138 (7). S. 544 - 557. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Engel, Julian, Richters, Andre, Getlik, Matthaeus, Tomassi, Stefano, Keul, Marina, Termathe, Martin ORCID: 0000-0002-5618-4633, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Becker, Christian, Mayer-Wrangowski, Svenja, Gruetter, Christian, Uhlenbrock, Niklas ORCID: 0000-0002-4489-9535, Kruell, Jasmin, Schaumann, Niklas, Eppmann, Simone, Kibies, Patrick, Hoffgaard, Franziska, Heil, Jochen, Menninger, Sascha, Ortiz-Cuaran, Sandra, Heuckmann, Johannes M., Tinnefeld, Verena, Zahedi, Rene P., Sos, Martin L., Schultz-Fademrecht, Carsten, Thomas, Roman K., Kast, Stefan M. and Rauh, Daniel ORCID: 0000-0002-1970-7642 (2015). Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. J. Med. Chem., 58 (17). S. 6844 - 6864. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Fernando, Ruani N., Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Escher, Sylvia E., Hengstler, Jan G., Hescheler, Juergen, Jennings, Paul ORCID: 0000-0002-6860-2898, Keun, Hector C., Kleinjans, Jos C. S., Kolde, Raivo ORCID: 0000-0003-2886-6298, Kollipara, Laxmikanth, Kopp-Schneider, Annette, Limonciel, Alice ORCID: 0000-0001-6588-5944, Nemade, Harshal, Nguemo, Filomain, Peterson, Hedi ORCID: 0000-0001-9951-5116, Prieto, Pilar, Rodrigues, Robim M., Sachinidis, Agapios, Schaefer, Christoph, Sickmann, Albert ORCID: 0000-0002-2388-5265, Spitkovsky, Dimitry, Stoeber, Regina, van Breda, Simone G. J., van de Water, Bob, Vivier, Manon, Zahedi, Rene P., Vinken, Mathieu ORCID: 0000-0001-5115-8893 and Rogiers, Vera ORCID: 0000-0003-0635-7740 (2016). Watching the Detectives report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015. Arch. Toxicol., 90 (6). S. 1529 - 1540. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Godoy, Patricio, Widera, Agata, Schmidt-Heck, Wolfgang, Campos, Gisela, Meyer, Christoph, Cadenas, Cristina, Reif, Raymond, Stoeber, Regina, Hammad, Seddik, Puetter, Larissa, Gianmoena, Kathrin, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, Ghallab, Ahmed ORCID: 0000-0003-0695-3403, Edlund, Karolina, Nuessler, Andreas, Thasler, Wolfgang E., Damm, Georg, Seehofer, Daniel, Weiss, Thomas S. ORCID: 0000-0003-0336-0581, Dirsch, Olaf, Dahmen, Uta, Gebhardt, Rolf, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Meganathan, Kesavan, Sachinidis, Agapios, Kelm, Jens, Hofmann, Ute ORCID: 0000-0003-0823-9027, Zahedi, Rene P., Guthke, Reinhard, Bluethgen, Nils, Dooley, Steven and Hengstler, Jan G. (2016). Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Arch. Toxicol., 90 (10). S. 2513 - 2530. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Huelsemann, Malte F., Patz, Michaela, Beckmann, Laura, Brinkmann, Kerstin, Otto, Teresa, Fandrey, Joachim, Becker, Hans Jiro, Theurich, Sebastian, von Bergwelt-Baildon, Michael S., Pallasch, Christian P., Zahedi, Rene P., Kashkar, Hamid, Reinhardt, Christian, Hallek, Michael, Wendtner, Clemens-Martin and Frenzel, Lukas P. (2014). p38 MAPK Controls Sensitivity Towards BH3 Mimetics By Regulating Mcl-1 Expression of Chronic Lymphocytic Leukemia in Hypoxia and Acquired Resistance. Blood, 124 (21). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Isensee, Joerg ORCID: 0000-0002-3390-0051, Kaufholz, Melanie, Knape, Matthias J., Hasenauer, Jan ORCID: 0000-0002-4935-3312, Hammerich, Hanna, Gonczarowska-Jorge, Humberto, Zahedi, Rene P., Schwede, Frank, Herberg, Friedrich W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2018). PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination. J. Cell Biol., 217 (6). S. 2167 - 2185. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-8140

Lategahn, Jonas ORCID: 0000-0001-5993-7082, Keul, Marina, Kloevekorn, Philip, Tumbrink, Hannah L., Niggenaber, Janina ORCID: 0000-0003-2942-263X, Mueller, Matthias P., Hodson, Luke, Flasshoff, Maren, Hardick, Julia, Grabe, Tobias, Engel, Julian, Schultz-Fademrecht, Carsten, Baumann, Matthias, Ketzer, Julia, Muehlenberg, Thomas, Hiller, Wolf, Guenther, Georgia, Unger, Anke, Mueller, Heiko, Heimsoeth, Alena, Golz, Christopher, Blank-Landeshammer, Bernhard, Kollipara, Laxmikanth, Zahedi, Rene P., Strohmann, Carsten ORCID: 0000-0002-4787-2135, Hengstler, Jan G., van Otterlo, Willem A. L., Bauer, Sebastian ORCID: 0000-0001-5949-8120 and Rauh, Daniel (2019). Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chem. Sci., 10 (46). S. 10789 - 10802. CAMBRIDGE: ROYAL SOC CHEMISTRY. ISSN 2041-6539

Plenker, Dennis, Riedel, Maximilian, Braegelmann, Johannes, Dammert, Marcel A., Chauhan, Rakhee, Knowles, Phillip P., Lorenz, Carina, Keul, Marina, Buehrmann, Mike, Pagel, Oliver, Tischler, Verena ORCID: 0000-0002-6673-8329, Scheel, Andreas H., Schtte, Daniel, Song, Yanrui, Stark, Justina, Mrugalla, Florian ORCID: 0000-0002-6281-6051, Alber, Yannic, Richters, Andre, Engel, Julian, Leenders, Frauke, Heuckmann, Johannes M., Wolf, Juergen, Diebold, Joachim, Pall, Georg, Peifer, Martin ORCID: 0000-0002-5243-5503, Aerts, Maarten, Gevaert, Kris ORCID: 0000-0002-4237-0283, Zahedi, Rene P., Buettner, Reinhard, Shokat, Kevan M., McDonald, Neil Q., Kast, Stefan M., Gautschi, Oliver, Thomas, Roman K. and Sos, Martin L. (2017). Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Sci. Transl. Med., 9 (394). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Rodrigues, Robim M., Chaudhari, Umesh, Kollipara, Laxmikanth, Sachinidis, Agapios, Zahedi, Rene P., Sickmann, Albert ORCID: 0000-0002-2388-5265, Keun, Hector, Kopp-Schneider, Annette, Jiang, Xiaoqi, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera M. and Vinken, Mathieu ORCID: 0000-0001-5115-8893 (2016). In vitro verification of an adverse outcome pathway of cholestasis. Hepatology, 64. S. 261A - 263. HOBOKEN: WILEY. ISSN 1527-3350

Rodrigues, Robim M., Kollipara, Laxmikanth, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Sachinidis, Agapios, Zahedi, Rene P., Sickmann, Albert ORCID: 0000-0002-2388-5265, Kopp-Schneider, Annette, Jiang, Xiaoqi, Keun, Hector, Hengstler, Jan, Oorts, Marlies, Annaert, Pieter, Hoeben, Eef, Gijbels, Eva ORCID: 0000-0002-7366-0769, De Kock, Joery ORCID: 0000-0002-4078-4896, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299, Rogiers, Vera ORCID: 0000-0003-0635-7740 and Vinken, Mathieu ORCID: 0000-0001-5115-8893 (2018). Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures. Arch. Toxicol., 92 (6). S. 1939 - 1953. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Rodrigues, Robim M., Kollipara, Laxmikanth, Chaudhari, Umesh, Sachinidis, Agapios, Zahedi, Rene P., Sickmann, Albert, Kopp-Schneider, Annette, Jiang, Xiaoqi, Keun, Hector, Hengstler, Jan, Vanhalewyn, Tineke, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera and Vinken, Mathieu ORCID: 0000-0001-5115-8893 (2017). Omics-based in vitro verification of an adverse outcome pathway of cholestatic liver injury. Toxicol. Lett., 280. S. S254 - 1. CLARE: ELSEVIER IRELAND LTD. ISSN 1879-3169

Saita, Shotaro ORCID: 0000-0002-7406-8361, Nolte, Hendrik, Fiedler, Kai Uwe, Kashkar, Hamid, Venne, A. Saskia, Zahedi, Rene P., Krueger, Marcus ORCID: 0000-0003-2008-4582 and Langer, Thomas (2017). PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat. Cell Biol., 19 (4). S. 318 - 355. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4679