Universität zu Köln

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Adams, Jana ORCID: 0000-0001-7711-9956, Klein, Christiane, Ludwig, Sebastian ORCID: 0000-0002-1627-1871, Stosch, Christoph ORCID: 0000-0003-1001-4310, Vogel, Kristina ORCID: 0000-0002-8695-1127, Bauer, Nicola H. ORCID: 0000-0002-7351-0832, Bruns, Christiane J. ORCID: 0000-0001-6590-8181 and Datta, Rabi R. ORCID: 0000-0002-6829-7379 (2025). V.T.O.B.S.—Learning birth mechanics in virtual reality: a controlled cohort study in undergraduate medical education. Frontiers in Medicine, 12. pp. 1-18. Frontiers. ISSN 2296-858X

Damanakis, Alexander I. ORCID: 0000-0002-1155-5541, Wahler, Isabell, Fuchs, Hans ORCID: 0000-0003-4764-8050, Löser, Heike ORCID: 0000-0003-4555-1327, Schröder, Wolfgang ORCID: 0000-0002-8700-069X, Zander, Thomas ORCID: 0000-0002-4266-6818, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Quaas, Alexander ORCID: 0000-0002-3537-6011 and Gebauer, Florian ORCID: 0000-0001-5312-4814 (2022). Integrin beta1 (ITGB1) as a prognostic marker in esophageal adenocarcinoma. Scientific Reports, 12 (1). p. 20745. Springer Nature. ISSN 2045-2322

Dapper, Hendrik ORCID: 0009-0005-8041-3634, Fleischmann, Maximilian, Tselis, Nikolaos, Diefenhardt, Markus ORCID: 0000-0002-9042-9729, Hofheinz, Ralf-Dieter, Weiß, Christian ORCID: 0009-0009-0497-2513, Grabenbauer, Gerhard G., Merten, Ricarda, Grosu, Anca-Ligia, Kirste, Simon, Rieken, Stefan, Claßen, Johannes, Langer, Christian, Kuhnt, Thomas, Schmidberger, Heinz, Ghadimi, Michael, Giordano, Frank, Nestle, Ursula, Koerber, Stefan A., Bock, Felix ORCID: 0009-0001-5795-9509, Geiger, Matthias, Polat, Bülent, Bruns, Christiane J., Dieplinger, Georg, Popp, Felix, Zander, Thomas, Brunner, Thomas, Tribius, Silke, Arnold, Dirk, Wurschi, Georg ORCID: 0000-0002-8751-9862, Piso, Pompiliu ORCID: 0000-0001-7146-4505, Friede, Tim ORCID: 0000-0001-5347-7441, Hörner-Rieber, Juliane, Gkika, Eleni, Rödel, Claus ORCID: 0009-0006-1777-2359 and Fokas, Emmanouil ORCID: 0000-0003-1601-6165 (2025). ACO/ARO/AIO-22 – External beam radiotherapy combined with endorectal high-dose-rate brachytherapy in elderly and frail patients with rectal cancer: A prospective multicentre trial of the German Rectal Cancer Study Group. Clinical and Translational Radiation Oncology, 53. p. 100958. Elsevier. ISSN 2405-6308

Drinhaus, Hendrik ORCID: 0000-0001-8435-2246, Mallmann, Christoph, Cleff, Corvin, Neumann, Tobias ORCID: 0000-0003-1858-7236, Daniels, Christina, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Steinbicker, Andrea U., Schröder, Wolfgang and Annecke, Thorsten ORCID: 0000-0002-2496-4432 (2025). Glycocalyx-Shedding and Inflammatory Reactions Occur Yet Do Not Predict Complications Resulting from an Esophagectomy in an Accelerated Recovery After Surgery Program. Journal of Clinical Medicine, 14 (17). MDPI. ISSN 2077-0383

Grothey, Bastian ORCID: 0000-0002-0883-6481, Lyu, Su Ir ORCID: 0009-0002-4125-6048, Quaas, Alexander ORCID: 0000-0002-3537-6011, Simon, Adrian Georg ORCID: 0000-0002-2709-863X, Jung, Jin-On ORCID: 0000-0001-6121-0114, Schröder, Wolfgang ORCID: 0000-0002-8700-069X, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Schiffmann, Lars M. ORCID: 0000-0002-2320-5004, Popp, Felix C. ORCID: 0000-0002-1690-6777, Schmidt, Thomas ORCID: 0000-0002-7166-3675 and Knipper, Karl ORCID: 0009-0008-7133-3538 (2025). Proteomic characterization of MET-amplified esophageal adenocarcinomas reveals enrichment of alternative splicing- and androgen signaling-related proteins. Cellular and Molecular Life Sciences, 82 (1). pp. 1-13. Springer Nature. ISSN 1420-9071

Ju, Feng, Weng, Jialei, Fan, Ningbo ORCID: 0000-0002-1622-6747, Wang, Zhefang ORCID: 0000-0002-2297-2586, Zhou, Chenghui ORCID: 0000-0003-1170-1761, Zhao, Xinlei, Horstmann, Nellie, Wu, Xiaolin ORCID: 0009-0006-3037-3328, Hoppe, Sascha, You, Bo ORCID: 0000-0002-3602-5264, Li, Keying, Duan, Jianxin, Odenthal, Margarete ORCID: 0000-0002-2424-0960, Hillmer, Axel M. ORCID: 0000-0002-3381-7266, Quaas, Alexander ORCID: 0000-0002-3537-6011, Bruns, Christiane J. ORCID: 0000-0001-6590-8181 and Zhao, Yue ORCID: 0000-0002-6790-3402 (2025). AKR1C3 enhances radioresistance in esophageal adenocarcinoma via inhibiting ferroptosis through suppressing TRIM21-mediated ubiquitination of HSPA5. Cell Death & Disease, 16 (1). pp. 1-16. Springer Nature. ISSN 2041-4889

Knipper, Karl ORCID: 0009-0008-7133-3538, Lyu, Su Ir ORCID: 0009-0002-4125-6048, Tzitzili, Eleni ORCID: 0000-0002-2465-9585, Spielmann, Sarah-Michele, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Schmidt, Thomas ORCID: 0000-0002-7166-3675, Popp, Felix C. ORCID: 0000-0002-1690-6777 and Quaas, Alexander ORCID: 0000-0002-3537-6011 (2025). Loss of Argininosuccinate Synthetase-1 (ASS1) Occurs in Esophageal Adenocarcinoma and Represents a Promising Biomarker for Therapy with Pegargiminase. Cancers, 17 (22). MDPI. ISSN 2072-6694

Knipper, Karl ORCID: 0009-0008-7133-3538, Damanakis, Alexander I. ORCID: 0000-0002-1155-5541, Lyu, Su Ir ORCID: 0009-0002-4125-6048, Simon, Adrian Georg ORCID: 0000-0002-2709-863X, Wahler, Isabell, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Schröder, Wolfgang ORCID: 0000-0002-8700-069X, Schmidt, Thomas ORCID: 0000-0002-7166-3675 and Quaas, Alexander ORCID: 0000-0002-3537-6011 (2023). High NANOG expression correlates with worse patients’ survival in esophageal adenocarcinoma. BMC Cancer, 23 (1). p. 669. Springer Nature. ISSN 1471-2407

Krauss, Dolores T., Fuchs, Hans F. ORCID: 0000-0003-4764-8050, Schaaf, Sebastian, Drossard, Sabine, Rösch, Romina, Blank, Beate, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Rolle, Udo, Schmitz-Rixen, Thomas and Kröplin, Juliane (2025). Ist der Einsatz digitaler Technologien der Gamechanger für die chirurgische Weiterbildung der Zukunft? Eine deutschlandweite Analyse. Die Chirurgie, 96 (9). pp. 755-764. Springer Nature. ISSN 2731-6971

Lyu, Su Ir ORCID: 0009-0002-4125-6048, Popp, Felix C. ORCID: 0000-0002-1690-6777, Simon, Adrian Georg ORCID: 0000-0002-2709-863X, Schultheis, Anne Maria ORCID: 0000-0002-9078-5432, Zander, Thomas ORCID: 0000-0002-4266-6818, Fretter, Caroline, Schröder, Wolfgang ORCID: 0000-0002-8700-069X, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Schmidt, Thomas ORCID: 0000-0002-7166-3675, Quaas, Alexander ORCID: 0000-0002-3537-6011 and Knipper, Karl ORCID: 0009-0008-7133-3538 (2023). Copy-number-gain of telomerase reverse transcriptase (hTERT) is associated with an unfavorable prognosis in esophageal adenocarcinoma. Scientific Reports, 13 (1). p. 17699. Springer Nature. ISSN 2045-2322

Raters, Verena Maria, Gebauer, Florian ORCID: 0000-0001-5312-4814, Löser, Heike ORCID: 0000-0003-4555-1327, Schröder, Wolfgang ORCID: 0000-0002-8700-069X, Schlösser, Hans Anton ORCID: 0000-0002-1304-7719, Fuchs, Hans ORCID: 0000-0003-4764-8050, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Quaas, Alexander ORCID: 0000-0002-3537-6011 and Zander, Thomas ORCID: 0000-0002-4266-6818 (2023). Combined score of Y chromosome loss and T-cell infiltration improves UICC based stratification of esophageal adenocarcinoma. Frontiers in Oncology, 13. pp. 1-9. Frontiers Research Foundation. ISSN 2234-943X

Scheel, Andreas H., Lamberty, Hannah, Tolkach, Yuri ORCID: 0000-0001-5239-2841, Gebauer, Florian ORCID: 0000-0001-5312-4814, Schömig-Markiefka, Birgid ORCID: 0000-0003-1893-8796, Zander, Thomas ORCID: 0000-0002-4266-6818, Büttner, Reinhard ORCID: 0000-0001-8806-4786, Rueschoff, Josef, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Schröder, Wolfgang ORCID: 0000-0002-8700-069X and Quaas, Alexander ORCID: 0000-0002-3537-6011 (2023). Tumour area infiltration and cell count in endoscopic biopsies of therapy-naive upper GI tract carcinomas by QuPath analysis: implications for predictive biomarker testing. Scientific Reports, 13 (1). p. 17580. Springer Nature. ISSN 2045-2322

Stoll, Sandra Emily ORCID: 0000-0002-4803-1362, Werner, Patrick, Wetsch, Wolfgang A. ORCID: 0000-0001-5800-6665, Dusse, Fabian ORCID: 0000-0001-7762-6966, Bunck, Alexander C. ORCID: 0000-0003-0986-0042, Kochanek, Matthias ORCID: 0000-0002-4766-4651, Popp, Felix ORCID: 0000-0002-1690-6777, Schmidt, Thomas ORCID: 0000-0002-7166-3675, Bruns, Christiane J. ORCID: 0000-0001-6590-8181 and Böttiger, Bernd W. ORCID: 0000-0001-8000-8931 (2022). Transjugular intrahepatic portosystemic shunt, local thrombaspiration, and lysis for management of fulminant portomesenteric thrombosis and atraumatic splenic rupture due to vector-vaccine-induced thrombotic thrombocytopenia: a case report. Journal of Medical Case Reports, 16 (1). p. 271. Springer Nature. ISSN 1752-1947

Wirsik, Naita M. ORCID: 0000-0003-1619-6354, Seeger, Jens M. ORCID: 0000-0002-3192-9192, Schmidt, Thomas ORCID: 0000-0002-7166-3675, Hilberg, Frank ORCID: 0000-0001-8925-7336, Fuchs, Hans F. ORCID: 0000-0003-4764-8050, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Coutelle, Oliver, Kashkar, Hamid ORCID: 0000-0003-2796-1429 and Schiffmann, Lars M. ORCID: 0000-0002-2320-5004 (2025). Impact of Nintedanib on tumor angiogenesis and vascular normalization in a mouse model of colorectal cancer. Discover Oncology, 16 (1). pp. 1-9. Springer Nature. ISSN 2730-6011

vom Stein, Alexander F. ORCID: 0000-0002-6910-7792, Rebollido-Rios, Rocio ORCID: 0000-0002-8910-867X, Lukas, Anna, Koch, Maximilian, von Lom, Anton ORCID: 0009-0005-6907-9962, Reinartz, Sebastian, Bachurski, Daniel ORCID: 0000-0001-9168-9680, Rose, France ORCID: 0000-0001-5828-3259, Bozek, Katarzyna ORCID: 0000-0002-0917-6876, Abdallah, Ali T., Kohlhas, Viktoria ORCID: 0000-0001-8133-1001, Saggau, Julia ORCID: 0000-0002-9908-5467, Zölzer, Rebekka, Zhao, Yue, Bruns, Christiane J. ORCID: 0000-0001-6590-8181, Bröckelmann, Paul J. ORCID: 0000-0001-9662-9900, Lohneis, Philipp, Büttner, Reinhard ORCID: 0000-0001-8806-4786, Häupl, Björn, Oellerich, Thomas ORCID: 0000-0001-6570-6125, Nguyen, Phuong-Hien ORCID: 0000-0002-3249-7264 and Hallek, Michael ORCID: 0000-0002-7425-4455 (2023). LYN kinase programs stromal fibroblasts to facilitate leukemic survival via regulation of c-JUN and THBS1. Nature Communications, 14 (1). p. 1330. Springer Nature. ISSN 2041-1723

Thesis

Schulte, Elena ORCID: 0000-0003-3052-0907, Müller, Dolores Thea, Schröder, Wolfgang, Fuchs, Hans F., Babic, Benjamin, Knepper, Laura, Fuchs, Claudia, Bruns, Christiane J. and Leers, Jessica M. (2020). Software improvement for evaluation of laryngopharyngeal ph testing (Restech)- a comparison between DataView 3 and 4. PhD thesis, Universität zu Köln.