Universität zu Köln

Journal Article

Adamo, Christin S. ORCID: 0000-0002-8560-6153, Beyens, Aude, Schiavinato, Alvise, Keene, Douglas R., Tufa, Sara F., Morgelin, Matthias, Brinckmann, Jurgen, Sasaki, Takako, Niehoff, Anja, Dreiner, Maren, Pottie, Lore, Muino-Mosquera, Laura, Gulec, Elif Yilmaz, Gezdirici, Alper ORCID: 0000-0002-2432-9279, Braghetta, Paola, Bonaldo, Paolo, Wagener, Raimund, Paulsson, Mats, Bornaun, Helen, De Rycke, Riet, De Bruyne, Michiel, Baeke, Femke, Devine, Walter P., Gangaram, Balram, Tam, Allison ORCID: 0000-0001-6940-9240, Balasubramanian, Meena ORCID: 0000-0003-1488-3695, Ellard, Sian, Moore, Sandra, Symoens, Sofie, Shen, Joseph, Cole, Stacey, Schwarze, Ulrike, Holmes, Kathryn W., Hayflick, Susan J., Wiszniewski, Wojciech, Nampoothiri, Sheela, Davis, Elaine C., Sakai, Lynn Y., Sengle, Gerhard and Callewaert, Bert (2022). EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis. Am. J. Hum. Genet., 109 (12). S. 2230 - 2254. CAMBRIDGE: CELL PRESS. ISSN 1537-6605

Adamo, Christin S. ORCID: 0000-0002-8560-6153, Zuk, Alexandra V. and Sengle, Gerhard (2021). The fibrillin microfibril/elastic fibre network: A critical extracellular supramolecular scaffold to balance skin homoeostasis. Exp. Dermatol., 30 (1). S. 25 - 38. HOBOKEN: WILEY. ISSN 1600-0625

Akasaka, Eijiro, Kleiser, Svenja ORCID: 0000-0003-2448-1710, Sengle, Gerhard, Bruckner-Tuderman, Leena and Nystroem, Alexander (2021). High Glucose Restraint of Acetylcholine-Induced Keratinocyte Epithelial-Mesenchymal Transition Is Mitigated by p38 Inhibition. J. Invest. Dermatol., 141 (6). S. 1450 - 1470. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Brauchle, Eva, Bauer, Hannah, Fernes, Patrick, Zuk, Alexandra, Schenke-Layland, Katja and Sengle, Gerhard (2017). Raman microspectroscopy as a diagnostic tool for the non-invasive analysis of fibrillin-1 deficiency in the skin and in the in vitro skin models. Acta Biomater., 52. S. 41 - 49. OXFORD: ELSEVIER SCI LTD. ISSN 1878-7568

Bultmann-Mellin, Insa, Conradi, Anne, Maul, Alexandra C., Dinger, Katharina, Wempe, Frank, Wohl, Alexander P., Imhof, Thomas, Wunderlich, F. Thomas, Bunck, Alexander C., Nakamura, Tomoyuki, Koli, Katri, Bloch, Wilhelm, Ghanem, Alexander, Heinz, Andrea ORCID: 0000-0002-8609-4460, Von Melchner, Harald, Sengle, Gerhard and Sterner-Kock, Anja (2015). Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms. Dis. Model. Mech., 8 (4). S. 403 - 416. CAMBRIDGE: COMPANY BIOLOGISTS LTD. ISSN 1754-8411

Bultmann-Mellin, Insa, Conradi, Anne, Maul, Alexandra C., Dinger, Katharina, Wempe, Frank, Wohl, Alexander P., Imhof, Thomas, Wunderlich, F. Thomas, Bunck, Alexander C., Nakamura, Tomoyuki, Koli, Katri, Bloch, Wilhelm, Ghanem, Alexander, Heinz, Andrea ORCID: 0000-0002-8609-4460, Von Melchner, Harald, Sengle, Gerhard and Sterner-Kock, Anja (2015). Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms. Dis. Model. Mech., 8 (4). S. 403 - 416. CAMBRIDGE: COMPANY BIOLOGISTS LTD. ISSN 1754-8411

Bultmann-Mellin, Insa, Essers, Jeroen, van Heijingen, Paula M., von Melchner, Harald, Sengle, Gerhard and Sterner-Kock, Anja ORCID: 0000-0002-2877-7116 (2016). Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice. Dis. Model. Mech., 9 (11). S. 1367 - 1375. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 1754-8411

Corallo, Diana ORCID: 0000-0001-7075-1414, Schiavinato, Alvise, Bizzotto, Dario, Milanetto, Martina, Guljelmovic, Marija, Keene, Douglas R., Sengle, Gerhard, Braghetta, Paola and Bonaldo, Paolo (2017). EMILIN3, an extracellular matrix molecule with restricted distribution in skin. Exp. Dermatol., 26 (5). S. 435 - 439. HOBOKEN: WILEY. ISSN 1600-0625

Eckes, Beate, Moinzadeh, Pia, Sengle, Gerhard, Hunzelmann, Nico and Krieg, Thomas (2014). Molecular and cellular basis of scleroderma. J. Mol. Med., 92 (9). S. 913 - 925. NEW YORK: SPRINGER. ISSN 1432-1440

Esho, Temitope, Tufa, Sara F., Kobbe, Birgit, Wohl, Alexander P., Sengle, Gerhard, Paulsson, Mats ORCID: 0000-0002-6846-857X, Keene, Douglas R. and Wagener, Raimund (2022). Anchoring Cords: A Distinct Suprastructure in the Developing Skin. J. Invest. Dermatol., 142 (11). S. 2940 - 2951. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Etich, Julia ORCID: 0000-0003-3238-6692, Rehberg, Mirko, Eckes, Beate, Sengle, Gerhard, Semler, Oliver and Zaucke, Frank ORCID: 0000-0002-7680-9354 (2020). Signaling pathways affected by mutations causing osteogenesis imperfecta. Cell. Signal., 76. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1873-3913

Furlan, Ariane G., Spanou, Chara E. S., Godwin, Alan R. F., Wohl, Alexander P., Zimmermann, Laura-Marie A. ORCID: 0000-0003-2126-9191, Imhof, Thomas, Koch, Manuel ORCID: 0000-0002-2962-7814, Baldock, Clair and Sengle, Gerhard (2021). A new MMP-mediated prodomain cleavage mechanism to activate bone morphogenetic proteins from the extracellular matrix. Faseb J., 35 (3). HOBOKEN: WILEY. ISSN 1530-6860

Heumueller, Stefanie Elisabeth, Talantikite, Maya, Napoli, Manon, Armengaud, Jean, Moergelin, Matthias, Hartmann, Ursula, Sengle, Gerhard, Paulsson, Mats, Moali, Catherine and Wagener, Raimund (2019). C-terminal proteolysis of the collagen VI alpha 3 chain by BMP-1 and proprotein convertase(s) releases endotrophin in fragments of different sizes. J. Biol. Chem., 294 (37). S. 13769 - 13781. ROCKVILLE: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Hiepen, Christian ORCID: 0000-0001-7345-6496, Jatzlau, Jerome ORCID: 0000-0002-1757-0267, Hildebrandt, Susanne, Kampfrath, Branka, Goktas, Melis, Murgai, Arunima ORCID: 0000-0001-9767-7402, Camacho, Jose Luis Cuellar, Haag, Rainer, Ruppert, Clemens, Sengle, Gerhard, Cavalcanti-Adam, Elisabetta Ada, Blank, Kerstin G. and Knaus, Petra (2019). BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGF beta responses and altered cell mechanics. PLoS. Biol., 17 (12). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1545-7885

Hoffmann, Thorben, Morcos, Yousef Ashraf Tawfik, Janoschek, Ruth ORCID: 0000-0002-1332-9353, Turnwald, Eva-Maria, Gerken, Antje, Mueller, Annette, Sengle, Gerhard, Doetsch, Joerg, Appel, Sarah ORCID: 0000-0003-0315-6513 and Hucklenbruch-Rother, Eva (2022). Correlation of metabolic characteristics with maternal, fetal and placental asprosin in human pregnancy. Endocr. Connect., 11 (3). BRISTOL: BIOSCIENTIFICA LTD. ISSN 2049-3614

Imhof, Thomas, Korkmaz, Yueksel, Koch, Manuel, Sengle, Gerhard and Schiavinato, Alvise (2020). EMILIN proteins are novel extracellular constituents of the dentin-pulp complex. Sci Rep, 10 (1). BERLIN: NATURE RESEARCH. ISSN 2045-2322

Koehler, Anna, Morgelin, Matthias, Gebauer, Jan M., Oecal, Sinan, Imhof, Thomas, Koch, Manuel, Nagata, Kazuhiro, Paulsson, Mats, Zaucke, Frank, Baumann, Ulrich and Sengle, Gerhard (2020). New specific HSP47 functions in collagen subfamily chaperoning. Faseb J., 34 (9). S. 12040 - 12053. HOBOKEN: WILEY. ISSN 1530-6860

Lockhart-Cairns, Michael P., Lim, Karen Tzia Wei, Zuk, Alexandra, Godwin, Alan R. F., Cain, Stuart A., Sengle, Gerhard and Baldock, Clair ORCID: 0000-0003-3497-1959 (2019). Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER. Matrix Biol., 77. S. 73 - 87. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802

Malfait, Fransiska, Forlino, Antonella, Sengle, Gerhard and Van Agtmael, Tom (2022). Editorial: Molecular Mechanisms of Heritable Connective Tissue Disorders. Front. Genet., 13. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-8021

Mayorca-Guiliani, Alejandro E., Willacy, Oliver ORCID: 0000-0002-1541-7795, Madsen, Chris D., Rafaeva, Maria, Heumueller, Stefanie Elisabeth, Bock, Felix, Sengle, Gerhard, Koch, Manuel, Imhof, Thomas, Zaucke, Frank ORCID: 0000-0002-7680-9354, Wagener, Raimund, Sasaki, Takako, Erler, Janine T. and Reuten, Raphael (2019). Decellularization and antibody staining of mouse tissues to map native extracellular matrix structures in 3D. Nat. Protoc., 14 (12). S. 3395 - 3426. LONDON: NATURE PUBLISHING GROUP. ISSN 1750-2799

Mularczyk, Ewa J., Singh, Mukti, Godwin, Alan R. F., Galli, Francessco, Humphreys, Neil, Adamson, Antony D., Mironov, Aleksandr, Cain, Stuart A., Sengle, Gerhard, Boot-Handford, Ray P., Cossu, Giulio, Kielty, Cay M. and Baldock, Clair ORCID: 0000-0003-3497-1959 (2018). ADAMTS10-mediated tissue disruption in Weill-Marchesani syndrome. Hum. Mol. Genet., 27 (21). S. 3675 - 3688. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Nuechel, Julian, Ghatak, Sushmita, Zuk, Alexandra V., Illerhaus, Anja, Morgelin, Matthias, Schoenborn, Katrin, Blumbach, Katrin, Wickstroem, Sara A., Krieg, Thomas, Sengle, Gerhard, Plomann, Markus and Eckes, Beate (2018). TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy, 14 (3). S. 465 - 487. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1554-8635

Pilecki, Bartosz ORCID: 0000-0001-8636-2245, Holm, Anne T., Schlosser, Anders, Moeller, Jesper B., Wohl, Alexander P., Zuk, Alexandra V., Heumueller, Stefanie E., Wallis, Russell ORCID: 0000-0002-8705-5295, Moestrup, Soren K., Sengle, Gerhard, Holmskov, Uffe ORCID: 0000-0002-2391-9445 and Sorensen, Grith L. (2016). Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin-and Fibrillin-binding Protein Involved in Elastic Fiber Formation. J. Biol. Chem., 291 (3). S. 1103 - 1115. BETHESDA: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Pottie, Lore ORCID: 0000-0001-5102-975X, Adamo, Christin S. ORCID: 0000-0002-8560-6153, Beyens, Aude, Luetke, Steffen, Tapaneeyaphan, Piyanoot, De Clercq, Adelbert ORCID: 0000-0003-2670-1684, Salmon, Phil L., De Rycke, Riet, Gezdirici, Alper ORCID: 0000-0002-2432-9279, Gulec, Elif Yilmaz, Khan, Naz, Urquhart, Jill E., Newman, William G., Metcalfe, Kay, Efthymiou, Stephanie ORCID: 0000-0003-4900-9877, Maroofian, Reza, Anwar, Najwa, Maqbool, Shazia, Rahman, Fatima, Altweijri, Ikhlass, Alsaleh, Monerah, Abdullah, Sawsan Mohamed, Al-Owain, Mohammad, Hashem, Mais, Houlden, Henry, Alkuraya, Fowzan S., Sips, Patrick ORCID: 0000-0001-9241-5980, Sengle, Gerhard and Callewaert, Bert ORCID: 0000-0002-9743-4205 (2021). Bi-allelic premature truncating variants in LTBP1 cause cutis laxa syndrome. Am. J. Hum. Genet., 108 (6). S. 1095 - 1115. CAMBRIDGE: CELL PRESS. ISSN 1537-6605

Przyklenk, Matthias, Georgieva, Veronika S. ORCID: 0000-0002-9234-2504, Metzen, Fabian ORCID: 0000-0002-5248-8218, Mostert, Sebastian, Kobbe, Birgit, Callewaert, Bert, Sengle, Gerhard, Brachvogel, Bent ORCID: 0000-0002-3923-0554, Mecham, Robert P., Paulsson, Mats, Wagener, Raimund, Koch, Manuel ORCID: 0000-0002-2962-7814 and Schiavinato, Alvise (2022). LTBP1 promotes fibrillin incorporation into the extracellular matrix. Matrix Biol., 110. S. 60 - 76. AMSTERDAM: ELSEVIER. ISSN 1569-1802

Przyklenk, Matthias, Heumueller, Stefanie Elisabeth, Freiburg, Carolin, Luetke, Steffen, Sengle, Gerhard, Koch, Manuel ORCID: 0000-0002-2962-7814, Paulsson, Mats, Schiavinato, Alvise and Wagener, Raimund (2022). Lack of evidence for a role of anthrax toxin receptors as surface receptors for collagen VI and for its cleaved-off C5 domain/endotrophin. iScience, 25 (10). CAMBRIDGE: CELL PRESS. ISSN 2589-0042

Richardson, Rebecca J., Gebauer, Jan M., Zhang, Jin-Li, Kobbe, Birgit, Keene, Douglas R., Karlsen, Kristina Rokenes, Richetti, Stefania, Wohl, Alexander P., Sengle, Gerhard, Neiss, Wolfram F., Paulsson, Mats, Hammerschmidt, Matthias and Wagener, Raimund (2014). AMACO Is a Component of the Basement Membrane-Associated Fraser Complex. J. Invest. Dermatol., 134 (5). S. 1313 - 1323. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1523-1747

Ruthard, Johannes, Hermes, Gabriele, Hartmann, Ursula, Sengle, Gerhard, Pongratz, Georg, Ostendorf, Benedikt, Schneider, Matthias, Hoellriegl, Stefan, Zaucke, Frank, Wagener, Raimund, Streichert, Thomas and Klatt, Andreas R. (2018). Identification of antibodies against extracellular matrix proteins in human osteoarthritis. Biochem. Biophys. Res. Commun., 503 (3). S. 1273 - 1278. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1090-2104

Schiavinato, Alvise, Keene, Douglas R., Imhof, Thomas, Doliana, Roberto ORCID: 0000-0002-8324-7564, Sasaki, Takako and Sengle, Gerhard (2017). Fibulin-4 deposition requires EMILIN-1 in the extracellular matrix of osteoblasts. Sci Rep, 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Schiavinato, Alvise, Keene, Douglas R., Wohl, Alexander P., Corallo, Diana ORCID: 0000-0001-7075-1414, Colombatti, Alfonso, Wagener, Raimund, Paulsson, Mats, Bonaldo, Paolo and Sengle, Gerhard (2016). Targeting of EMILIN-1 and EMILIN-2 to Fibrillin Microfibrils Facilitates their Incorporation into the Extracellular Matrix. J. Invest. Dermatol., 136 (6). S. 1150 - 1161. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Schulz, Jan-Nikias, Plomann, Markus, Sengle, Gerhard, Gullberg, Donald ORCID: 0000-0002-7245-4437, Krieg, Thomas and Eckes, Beate (2018). New developments on skin fibrosis - Essential signals emanating from the extracellular matrix for the control of myofibroblasts. Matrix Biol., 68-69. S. 522 - 533. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802

Sengle, Gerhard and Sakai, Lynn V. (2015). The fibrillin microfibril scaffold: A niche for growth factors and mechanosensation? Matrix Biol., 47. S. 3 - 13. AMSTERDAM: ELSEVIER. ISSN 1569-1802

Troilo, Helen ORCID: 0000-0003-0537-1786, Barrett, Anne L., Wohl, Alexander P., Jowitt, Thomas A., Collins, Richard F., Bayley, Christopher P., Zuk, Alexandra V., Sengle, Gerhard and Baldock, Clair ORCID: 0000-0003-3497-1959 (2015). The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity. Biochem. Soc. Trans., 43. S. 795 - 801. LONDON: PORTLAND PRESS LTD. ISSN 1470-8752

Troilo, Helen ORCID: 0000-0003-0537-1786, Barrett, Anne L., Zuk, Alexandra V., Lockhart-Cairns, Michael P., Wohl, Alexander P., Bayley, Christopher P., Dajani, Rana, Tunnicliffe, Richard B., Green, Lewis, Jowitt, Thomas A., Sengle, Gerhard and Baldock, Clair ORCID: 0000-0003-3497-1959 (2016). Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway. Matrix Biol., 55. S. 49 - 63. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802

Troilo, Helen ORCID: 0000-0003-0537-1786, Zuk, Alexandra V., Tunnicliffe, Richard B., Wohl, Alexander P., Berry, Richard, Collins, Richard F., Jowitt, Thomas A., Sengle, Gerhard and Baldock, Clair ORCID: 0000-0003-3497-1959 (2014). Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding. Proc. Natl. Acad. Sci. U. S. A., 111 (36). S. 13063 - 13069. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Vallecillo-Garcia, Pedro, Orgeur, Mickael, vom Hofe-Schneider, Sophie, Stumm, Juergen, Kappert, Verena, Ibrahim, Daniel M., Boerno, Stefan T., Hayashi, Shinichiro ORCID: 0000-0001-5553-7698, Relaix, Frederic ORCID: 0000-0003-1270-1472, Hildebrandt, Katrin, Sengle, Gerhard, Koch, Manuel, Timmermann, Bernd, Marazzi, Giovanna, Sassoon, David A., Duprez, Delphine ORCID: 0000-0003-0248-7417 and Stricker, Sigmar ORCID: 0000-0002-7174-5363 (2017). Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development. Nat. Commun., 8. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Welcker, Daniela, Stein, Cornelia, Feitosa, Natalia Martins, Armistead, Joy, Zhang, Jin-Li, Luetke, Steffen, Kleinridders, Andre ORCID: 0000-0002-4248-6366, Bruening, Jens C., Eming, Sabine A., Sengle, Gerhard, Niehoff, Anja, Bloch, Wilhelm and Hammerschmidt, Matthias (2021). Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep, 11 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

Willenborg, Sebastian, Eckes, Beate, Juengst, Christian, Sengle, Gerhard, Zaucke, Frank ORCID: 0000-0002-7680-9354 and Eming, Sabine A. (2018). Myeloid Cell-Restricted STAT3 Signaling Controls a Cell-Autonomous Antifibrotic Repair Program. J. Immunol., 201 (2). S. 663 - 675. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Wohl, Alexander P., Troilo, Helen ORCID: 0000-0003-0537-1786, Collins, Richard F., Baldock, Clair ORCID: 0000-0003-3497-1959 and Sengle, Gerhard (2016). Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1. J. Biol. Chem., 291 (24). S. 12732 - 12747. BETHESDA: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Yin, Wenguang, Kim, Hyun-Taek, Wang, ShengPeng, Gunawan, Felix ORCID: 0000-0002-5592-9680, Li, Rui, Buettner, Carmen, Grohmann, Beate, Sengle, Gerhard, Sinner, Debora, Offermanns, Stefan and Stainier, Didier Y. R. (2019). Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur. Resp. J., 53 (3). SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. ISSN 1399-3003

Zhang, Jin-Li, Richetti, Stefania, Ramezani, Thomas, Welcker, Daniela, Luetke, Steffen, Pogoda, Hans-Martin, Hatzold, Julia, Zaucke, Frank, Keene, Douglas R., Bloch, Wilhelm, Sengle, Gerhard and Hammerschmidt, Matthias (2022). Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2. Matrix Biol., 112. AMSTERDAM: ELSEVIER. ISSN 1569-1802

Zigrino, Paola ORCID: 0000-0002-7470-0064 and Sengle, Gerhard (2019). Fibrillin microfibrils and proteases, key integrators of fibrotic pathways. Adv. Drug Deliv. Rev., 146. S. 3 - 17. AMSTERDAM: ELSEVIER. ISSN 1872-8294

Zimmermann, Laura-Marie A. ORCID: 0000-0003-2126-9191, Correns, Annkatrin ORCID: 0000-0002-2197-1717, Furlan, Ariane G., Spanou, Chara E. S. and Sengle, Gerhard (2021). Controlling BMP growth factor bioavailability: The extracellular matrix as multi skilled platform. Cell. Signal., 85. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1873-3913