Universität zu Köln

2024

Klußmann, Merlin Jan ORCID: 0000-0001-6041-0501 (2024). Investigating the activity and function of cell-permeable CaaX-peptides derived from Ras GTPases. Thesis Abstract, Universität zu Köln.

2023

Zimmermann, Laura-Marie (2023). Aortic pathomechanism induced by defined fibrillin-1 deficiency. Thesis Abstract, Universität zu Köln.

Wojtalla, Fabian ORCID: 0000-0001-7002-8955 (2023). Development of in vivo protease activity assays utilizing circularly permuted Photinus pyralis luciferase and a cell display split GFP approach with application to a zinc dependent metalloprotease from Vibrio cholerae. Thesis Abstract, Universität zu Köln.

Peker, Esra ORCID: 0000-0002-7730-9271 (2023). A two-step mitochondrial protein import pathway to regulate protein stability. Thesis Abstract, Universität zu Köln.

Lapacz, Kim Jasmin ORCID: 0000-0002-2494-4124 (2023). Multiprotease surveillance of Adenylate kinase 2. Thesis Abstract, Universität zu Köln.

2022

Abraham, Elena Theres ORCID: 0000-0002-3255-8565 (2022). Investigation of the expanded clientele of HSP47 or: finding your match(es) in the cell. Thesis Abstract, Universität zu Köln.

2021

Chen, Zhuoyan ORCID: 0000-0003-1640-5494 (2021). Purification and stabilisation of an atypical HCN channel for structural studies. Thesis Abstract, Universität zu Köln.

Mellis, Anna-Theresa (2021). Sulfite Metabolism in Health and Disease: Biogenesis, Biochemical Changes and Mitochondrial Morphology. Thesis Abstract, Universität zu Köln.

Klimpel, Annika (2021). Expanding the potential of cell-penetrating peptides via the incorporation of different targeting moieties. Thesis Abstract, Universität zu Köln.

Lützenburg, Tamara (2021). Intrinsic and extrinsic approaches to modulate the structure-activity relationship of cell-penetrating peptides. Thesis Abstract, Universität zu Köln.

2020

Höhne, Michaela Nicole (2020). Metabolic control of mitochondrial H2O2 release at a glance. Thesis Abstract, Universität zu Köln.

Salscheider, Silja Lucia (2020). A persistent AIFM1-MIA40 complex enablescomplex I assembly by controlling NDUFS5 biogenesis. Thesis Abstract, Universität zu Köln.

Nolte, Johannes Christoph (2020). Screening and characterization of biocatalysts for the glycosylation of natural products. Thesis Abstract, Universität zu Köln.

Murschall, Lena Maria (2020). The conserved negatively charged C-terminal region of human MIA40 stabilizes the precursor in the cytosol during slow mitochondrial import. Thesis Abstract, Universität zu Köln.

2019

Finger, Yannik Manuel (2019). Adenylate Kinase 2 is a novel disulfide relay substrate dually targeted to cytosol and mitochondria with a distinct enzymatic profile. Thesis Abstract, Universität zu Köln.

Heumüller, Stefanie Elisabeth (2019). Freisetzung von potenziell bioaktiven Fragmenten durch proteolytische Spaltung der Kollagen VI a3 Kette. Thesis Abstract, Universität zu Köln.

Solomon-Degefa, Herimela (2019). Structural and functional characterisation of collagen VI: Implications in the development of myopathies. Thesis Abstract, Universität zu Köln.

Kaczmarek, Alexander Tobias (2019). Reaction mechanism and physiologic relevance of sulfite oxidase-dependent NO formation. Thesis Abstract, Universität zu Köln.

Kohl, Joshua Benedict (2019). A Novel Mouse Model of Sulfite Oxidase Deficiency: Pathological Changes in Cysteine and H2S Metabolism. Thesis Abstract, Universität zu Köln.

Montada, Angelika Anna Maria (2019). Biochemical and Genetic Characterisation of the U32 Peptidase Family. Thesis Abstract, Universität zu Köln.

Mayr, Simon Julius (2019). Maturation, Function and Genetic Variation of Human Molybdenum Cofactor Synthesis 1 proteins in Health and Disease. Thesis Abstract, Universität zu Köln.

Merkler, Yvonne (2019). Characterization of gephyrin splice variants in postsynaptic inhibitory receptor clustering. Thesis Abstract, Universität zu Köln.

Calabrese, Gaetano ORCID: 0000-0002-2212-5280 (2019). A NADPH-independent switch-off mechanism protects mitochondrial EGSH from oxidation and H2O2-induced cell death. Thesis Abstract, Universität zu Köln.

Habich, Markus Andreas (2019). Quality Control Processes in IMS Protein Import. Thesis Abstract, Universität zu Köln.

Schrage, Kathrin (2019). Biochemical characterization of – Filippi syndrome mutated protein – CKAP2L. Thesis Abstract, Universität zu Köln.

2018

Gießler Furlan, Ariane (2018). New mechanisms involved in aortic aneurysm formation due to fibrillin-1 deficiency. Thesis Abstract, Universität zu Köln.

Lau, Daniela (2018). Biochemische Charakterisierung des knorpelspezifischen C-Typ Lektins CLEC3A. Thesis Abstract, Universitätsklinikum Köln.

Tan, Zhiyang (2018). Supramolecular Structure of Visual Pigments in Chicken Photoreceptors. Thesis Abstract, Universität zu Köln.

Manchanda, Kashish (2018). Myeloperoxidase leads to a collapse of the endothelial glycocalyx via physical interaction. Thesis Abstract, Universität zu Köln.

Song, Lin (2018). Functional characterization of wild-type and N471D strumpellin in hereditary spastic paraplegia. Thesis Abstract, Universität zu Köln.

2017

Erdogan, Alican (2017). The disulfide relay in the IMS of mammalian mitochondria is crucial for complex I biogenesis. Thesis Abstract, Universität zu Köln.

Pichlo, Christian (2017). Structural and Biochemical Characterization of Metallopeptidases from Enteropathogenic Bacteria. Thesis Abstract, Universität zu Köln.

Kumar, Avadh (2017). Molecular Mechanism of Neurodegeneration in Molybdenum Cofactor Deficiency. Thesis Abstract, Universität zu Köln.

Baatout, Dunja (2017). Impact of protein thioesterase 1 and 2 on relevant cancer pathways and intercellular communication of malignant B cells. Thesis Abstract, Universität zu Köln.

2016

Ebert, Silvia (2016). The Relationship of Palmitoylation, Nitrosylation and Phosphorylation in Synaptic Gephyrin Clustering. Thesis Abstract, Universität zu Köln.

Kress, Vanessa (2016). Collective Regulation of Synaptic Plasticity by Gephyrin, Dynein Light Chain and Neuronal Nitric Oxide Synthase. Thesis Abstract, Universität zu Köln.

2015

Grünewald, Nora (2015). The Molecular Mechanism of Gephyrin Binding to the Glycine Receptor: Regulation, Binding Sites and Novel Model Systems. Thesis Abstract, Universität zu Köln.

2014

Arjune, Sita ORCID: 0000-0002-6121-4614 (2014). Oxidative Cysteine Catabolism in Humans: Characterization of the Oxygenation and Transamination Reaction. Thesis Abstract, Universität zu Köln.

Csaszar, Julika (2014). Katabolismus des Molybdän-Cofaktors - Identifikation der endogenen Thiopterin-Methyltransferase. Thesis Abstract, Universität zu Köln.

Berg, Valeska (2014). Untersuchungen zur Rolle von APT1 und APT2 bei der Induktion Todesrezeptor-vermittelter Apoptose in der CLL. Thesis Abstract, Universität zu Köln.

Liebrecht, Valérie Isabelle (2014). Adoptiv transferierte T-Zellen mit FAP (fibroblast activation protein)-Spezifität verhindern die Tumoretablierung. Thesis Abstract, Universität zu Köln.

Krizowski, Sabina (2014). Nitrite dependent NO synthesis in humans: A novel function of Sulfite Oxidase. Thesis Abstract, Universität zu Köln.

2013

Rahn, Elena (2013). Eintritt des Herpes simplex Virus Typ 1 in Keratinozyten: Charakterisierung der beteiligten zellulären Faktoren. Thesis Abstract, Universität zu Köln.

Havarushka, Nastassia (2013). Tungsten Cofactor Biosynthesis in Pyrococcus furiosus: Structural Basis of Thermal Stability of the Adenylyl-transferase and Aspects of Cofactor Maturation. Thesis Abstract, Universität zu Köln.

Fröhlich, Michael (2013). Der Einfluss von S-Palmitoylierung auf die pro-apoptotische Aktivität des BCL2-Proteins BAX. Thesis Abstract, Universität zu Köln.

2012

Röper, Juliane (2012). Mitochondriale Funktionen in der Biosynthese und Defizienz des Molybdän-Cofaktors im Menschen. Thesis Abstract, Universität zu Köln.

Chi, Jen-Chih (2012). Molecular mechanism of 14-3-3-mediated inhibition of plant nitrate reductase. Thesis Abstract, Universität zu Köln.

Keib, Natalie (2012). Identifizierung und Charakterisierung von Interaktionspartnern der Gephyrin C-Domäne. Thesis Abstract, Universität zu Köln.

Herweg, Jens (2012). Biochemische Charakterisierung von Gephyrin: Oligomerisierung, posttranslationale Modifikationen und Glycin-Rezeptor Interaktion. Thesis Abstract, Universität zu Köln.

Dejanovic, Borislav (2012). Gephyrin palmitoylation and oligomerization in synaptic plasticity, membrane recruitment and proteostasis. Thesis Abstract, Universität zu Köln.

2011

Lilienthal, Nils (2011). Targeting apoptotic resistance in chronic lymphocytic leukemia (CLL). Thesis Abstract, Universität zu Köln.

Belaidi, Abdel Ali (2011). Human Molybdenum Cofactor Biosynthesis and Deficiency: Novel Functions and Therapies. Thesis Abstract, Universität zu Köln.

Schwiese, Oliver (2011). Biochemische und funktionelle Charakterisierung der Interaktion von Gephyrin und Dynein Light Chain. Thesis Abstract, Universität zu Köln.

2010

Radhakrishnan, Kayalvizhi (2010). Activation and trafficking of CaV2.3 Calcium Channel. Thesis Abstract, Universität zu Köln.

2009

Lambeck, Iris (2009). Post-translationale Regulation der Nitratreduktase durch Phosphorylierung und 14-3-3-Protein-Bindung. Thesis Abstract, Universität zu Köln.

Smolinsky, Birthe (2009). Duale Funktion von Gephyrin: Clustern von inhibitorischen Neurorezeptoren und Molybdäncofaktor-Synthese. Thesis Abstract, Universität zu Köln.

2006

Harzheim, Dagmar (2006). Der Einfluss von cAMP auf die physiologische Funktion von HCN4-Schrittmacherkanälen in der Maus. Thesis Abstract, Universität zu Köln.

2005

Kaschani, Farnusch (2005). Untersuchungen zur Regulation des homöotischen Blütengens DEFICIENS in Antirrhinum majus. Thesis Abstract, Universität zu Köln.