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Journal Article
Hommen, Franziska ORCID: 0000-0002-1612-6973, Bilican, Saygin
ORCID: 0000-0001-9448-6504 and Vilchez, David
ORCID: 0000-0002-0801-0743
(2022).
Protein clearance strategies for disease intervention.
J. Neural Transm., 129 (2).
S. 141 - 173.
WIEN:
SPRINGER WIEN.
ISSN 1435-1463
Sarroca, Sara, Gatius, Alao, Rodriguez-Farre, Eduard ORCID: 0000-0001-9305-3168, Vilchez, David
ORCID: 0000-0002-0801-0743, Pallas, Merce, Grinan-Ferre, Christian, Sanfeliu, Coral
ORCID: 0000-0002-9004-1206 and Corpas, Ruben
ORCID: 0000-0002-7051-1493
(2021).
Resveratrol confers neuroprotection against high-fat diet in a mouse model of Alzheimer's disease via modulation of proteolytic mechanisms.
J. Nutr. Biochem., 89.
NEW YORK:
ELSEVIER SCIENCE INC.
ISSN 1873-4847
Koyuncu, Seda, Loureiro, Rute ORCID: 0000-0002-2023-2429, Lee, Hyun Ju, Wagle, Prerana, Krueger, Marcus and Vilchez, David
ORCID: 0000-0002-0801-0743
(2021).
Rewiring of the ubiquitinated proteome determines ageing in C. elegans.
Nature, 596 (7871).
S. 285 - 317.
BERLIN:
NATURE PORTFOLIO.
ISSN 1476-4687
Saez, Isabel, Gerbracht, Jennifer, V, Koyuncu, Seda, Lee, Hyun Ju, Horn, Moritz, Kroef, Virginia, Denzel, Martin S., Dieterich, Christoph, Gehring, Niels H. ORCID: 0000-0001-7792-1164 and Vilchez, David
ORCID: 0000-0002-0801-0743
(2020).
The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.
FEBS Lett., 594 (1).
S. 175 - 189.
HOBOKEN:
WILEY.
ISSN 1873-3468
Lee, Hyun Ju, Noormohammadi, Alireza, Koyuncu, Seda, Calculli, Giuseppe, Simic, Milos S., Herholz, Marija, Trifunovic, Aleksandra ORCID: 0000-0002-5472-3517 and Vilchez, David
ORCID: 0000-0002-0801-0743
(2019).
Prostaglandin signals from adult germline stem cells delay somatic ageing of Caenorhabditis elegans.
Nat. Metab., 1 (8).
S. 790 - 811.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2522-5812
Saez, Isabel, Koyuncu, Seda, Gutierrez-Garcia, Ricardo, Dieterich, Christoph and Vilchez, David ORCID: 0000-0002-0801-0743
(2018).
Insights into the ubiquitin-proteasome system of human embryonic stem cells.
Sci Rep, 8.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2045-2322
Irmak, Dilber, Fatima, Azra, Gutierrez-Garcia, Ricardo, Rinschen, Markus M., Wagle, Prerana, Altmueller, Janine, Arrigoni, Laura, Hummel, Barbara ORCID: 0000-0001-6563-3675, Klein, Corinna, Frese, Christian K., Sawarkar, Ritwick, Rada-Iglesias, Alvaro
ORCID: 0000-0001-7137-1341 and Vilchez, David
ORCID: 0000-0002-0801-0743
(2018).
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.
Hum. Mol. Genet., 27 (23).
S. 4117 - 4135.
OXFORD:
OXFORD UNIV PRESS.
ISSN 1460-2083
Noormohammadi, Alireza, Calculli, Giuseppe, Gutierrez-Garcia, Ricardo, Khodakarami, Amirabbas, Koyuncu, Seda and Vilchez, David ORCID: 0000-0002-0801-0743
(2018).
Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells.
Cell. Mol. Life Sci., 75 (2).
S. 275 - 291.
BASEL:
SPRINGER BASEL AG.
ISSN 1420-9071
Goncalves, Ines do Carmo G., Brecht, Johanna, Thelen, Maximilian P., Rehorst, Wiebke A., Peters, Miriam, Lee, Hyun Ju, Motameny, Susanne, Torres-Benito, Laura, Ebrahimi-Fakhari, Darius ORCID: 0000-0002-0026-4714, Kononenko, Natalia L., Altmueller, Janine, Vilchez, David
ORCID: 0000-0002-0801-0743, Sahin, Mustafa, Wirth, Brunhilde
ORCID: 0000-0003-4051-5191 and Kye, Min Jeong
ORCID: 0000-0002-1323-7256
(2018).
Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Sci Rep, 8.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2045-2322
Koyuncu, Seda, Saez, Isabel, Lee, Hyun Ju, Gutierrez-Garcia, Ricardo, Pokrzywa, Wojciech ORCID: 0000-0002-5110-4462, Fatima, Azra, Hoppe, Thorsten
ORCID: 0000-0002-4734-9352 and Vilchez, David
ORCID: 0000-0002-0801-0743
(2018).
The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients.
Nat. Commun., 9.
BERLIN:
NATURE RESEARCH.
ISSN 2041-1723
Lee, Hyun Ju, Gutierrez-Garcia, Ricardo and Vilchez, David ORCID: 0000-0002-0801-0743
(2017).
Embryonic stem cells: a novel paradigm to study proteostasis?
FEBS J., 284 (3).
S. 391 - 399.
HOBOKEN:
WILEY-BLACKWELL.
ISSN 1742-4658
Koyuncu, Seda, Fatima, Azra, Gutierrez-Garcia, Ricardo and Vilchez, David ORCID: 0000-0002-0801-0743
(2017).
Proteostasis of Huntingtin in Health and Disease.
Int. J. Mol. Sci., 18 (7).
BASEL:
MDPI.
ISSN 1422-0067
Lee, Hyun Ju, Bartsch, Deniz, Xiao, Cally ORCID: 0000-0001-7172-3175, Guerrero, Santiago
ORCID: 0000-0003-3473-7214, Ahuja, Gaurav
ORCID: 0000-0002-2837-9361, Schindler, Christina, Moresco, James J., Yates, John R., III, Gebauer, Fatima
ORCID: 0000-0001-7563-0013, Bazzi, Hisham
ORCID: 0000-0001-8388-4005, Dieterich, Christoph, Kurian, Leo
ORCID: 0000-0001-7466-5169 and Vilchez, David
ORCID: 0000-0002-0801-0743
(2017).
A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.
Nat. Commun., 8.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2041-1723
Noormohammadi, Alireza, Khodakarami, Amirabbas, Gutierrez-Garcia, Ricardo, Lee, Hyun Ju, Koyuncu, Seda, Nig, Tim Ko, Schindler, Christina, Saez, Isabel, Fatima, Azra, Dieterich, Christoph and Vilchez, David ORCID: 0000-0002-0801-0743
(2016).
Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C-elegans lifespan.
Nat. Commun., 7.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2041-1723
Rinschen, Markus M., Bharill, Puneet, Wu, Xiongwu, Kohli, Priyanka ORCID: 0000-0002-0651-4008, Reinert, Matthaeus J., Kretz, Oliver, Saez, Isabel, Schermer, Bernhard
ORCID: 0000-0002-5194-9000, Hoehne, Martin, Bartram, Malte P., Aravamudhan, Sriram, Brooks, Bernard R., Vilchez, David
ORCID: 0000-0002-0801-0743, Huber, Tobias B.
ORCID: 0000-0001-7175-5062, Mueller, Roman-Ulrich, Krueger, Marcus
ORCID: 0000-0003-2008-4582 and Benzing, Thomas
(2016).
The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.
Hum. Mol. Genet., 25 (7).
S. 1328 - 1345.
OXFORD:
OXFORD UNIV PRESS.
ISSN 1460-2083
Koyuncu, Seda, Irmak, Dither, Saez, Isabel and Vilchez, David ORCID: 0000-0002-0801-0743
(2015).
Defining the General Principles of Stem Cell Aging: Lessons from Organismal Models.
Curr. Stem. Cell Rep., 1 (3).
S. 162 - 170.
HEIDELBERG:
SPRINGER HEIDELBERG.
ISSN 2198-7866
Khodakarami, Amirabbas, Saez, Isabel, Mels, Johanna and Vilchez, David ORCID: 0000-0002-0801-0743
(2015).
Mediation of organismal aging and somatic proteostasis by the germline.
Front. Mol. Biosci., 2.
LAUSANNE:
FRONTIERS MEDIA SA.
ISSN 2296-889X
Saez, Isabel and Vilchez, David ORCID: 0000-0002-0801-0743
(2015).
Protein clearance mechanisms and their demise in age-related neurodegenerative diseases.
AIMS Mol. Sci., 2 (1).
S. 1 - 22.
SPRINGFIELD:
AMER INST MATHEMATICAL SCIENCES-AIMS.
ISSN 2372-0301
Saez, Isabel and Vilchez, David ORCID: 0000-0002-0801-0743
(2014).
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases.
Curr. Genomics, 15 (1).
S. 38 - 52.
SHARJAH:
BENTHAM SCIENCE PUBL LTD.
ISSN 1875-5488
Vilchez, David ORCID: 0000-0002-0801-0743, Simic, Milos S. and Dillin, Andrew
(2014).
Proteostasis and aging of stem cells.
Trends Cell Biol., 24 (3).
S. 161 - 171.
LONDON:
ELSEVIER SCIENCE LONDON.
ISSN 0962-8924
Vilchez, David ORCID: 0000-0002-0801-0743, Saez, Isabel and Dillin, Andrew
(2014).
The role of protein clearance mechanisms in organismal ageing and age-related diseases.
Nat. Commun., 5.
LONDON:
NATURE PUBLISHING GROUP.
ISSN 2041-1723