Universität zu Köln

Journal Article

Andres, Christine, Hasenauer, Jan ORCID: 0000-0002-4935-3312, Ahn, Hye-Sook, Joseph, Elizabeth K., Isensee, Joerg ORCID: 0000-0002-3390-0051, Theis, Fabian J., Allgoewer, Frank, Levine, Jon D., Dib-Hajj, Sulayman D., Waxman, Stephen G. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2013). Wound-healing growth factor, basic FGF, induces Erk1/2-dependent mechanical hyperalgesia. Pain, 154 (10). S. 2216 - 2227. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1872-6623

Cai, Song, Moutal, Aubin ORCID: 0000-0003-4268-1206, Yu, Jie ORCID: 0000-0002-6768-7236, Chew, Lindsey A., Isensee, Jorg, Chawla, Reena, Gomez, Kimberly ORCID: 0000-0003-1867-5041, Luo, Shizhen, Zhou, Yuan, Chefdeville, Aude, Madura, Cynthia, Perez-Miller, Samantha ORCID: 0000-0002-9034-3693, Bellampalli, Shreya Sai, Dorame, Angie, Scott, David D., Francois-Moutal, Liberty, Shan, Zhiming ORCID: 0000-0002-4575-3933, Woodward, Taylor, Gokhale, Vijay, Hohmann, Andrea G., Vanderah, Todd W., Patek, Marcel, Khanna, May, Hucho, Tim and Khanna, Rajesh (2021). Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents. Sci. Transl. Med., 13 (619). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

El-Awaad, Ehab, Pryymachuk, Galyna, Fried, Cora, Matthes, Jan ORCID: 0000-0003-2754-1555, Isensee, Joerg, Hucho, Tim, Neiss, Wolfram F., Paulsson, Mats, Herzig, Stefan, Zaucke, Frank and Pietsch, Markus (2019). Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit alpha(2)delta-1 with thrombospondin-4. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Erber, Johanna ORCID: 0000-0001-6614-6051, Steiner, Joachim D., Isensee, Joerg ORCID: 0000-0002-3390-0051, Lobbes, Leonard A., Toschka, Andre, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Schmitt, Anna, Kaiser, Rainer W. J., Siedek, Florian, Persigehl, Thorsten, Hucho, Tim and Reinhardt, Hans C. (2019). Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells. Cancer Res., 79 (19). S. 4855 - 4869. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Garza Carbajal, Anibal, Ebersberger, Andrea, Thiel, Alina, Ferrari, Luiz, Acuna, Jeremy, Brosig, Stephanie, Isensee, Joerg, Moeller, Katharina, Siobal, Maike, Rose-John, Stefan ORCID: 0000-0002-7519-3279, Levine, Jon, Schaible, Hans-Georg and Hucho, Tim . Oncostatin M induces hyperalgesic priming and amplifies signaling of cAMP to ERK by RapGEF2 and PKA. J. Neurochem.. HOBOKEN: WILEY. ISSN 1471-4159

Hasenauer, Jan ORCID: 0000-0002-4935-3312, Hasenauer, Christine, Hucho, Tim ORCID: 0000-0002-4147-9308 and Theis, Fabian J. (2014). ODE Constrained Mixture Modelling: A Method for Unraveling Subpopulation Structures and Dynamics. PLoS Comput. Biol., 10 (7). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1553-7358

Hucho, Tim ORCID: 0000-0002-4147-9308, Suckow, Vanessa, Joseph, Elizabeth K., Kuhn, Julia, Schmoranzer, Jan ORCID: 0000-0002-4482-7080, Dina, Olayinka A., Chen, Xiaojie, Karst, Matthias, Bernateck, Michael, Levine, Jon D. and Ropers, Hans-Hilger (2012). Ca++/CaMKII switches nociceptor-sensitizing stimuli into desensitizing stimuli. J. Neurochem., 123 (4). S. 589 - 602. HOBOKEN: WILEY. ISSN 1471-4159

Hussong, Michelle, Kaehler, Christian, Kerick, Martin ORCID: 0000-0002-6298-4514, Grimm, Christina ORCID: 0000-0002-4676-8870, Franz, Alexandra, Timmermann, Bernd, Welzel, Franziska, Isensee, Joerg ORCID: 0000-0002-3390-0051, Hucho, Tim ORCID: 0000-0002-4147-9308, Krobitsch, Sylvia and Schweiger, Michal R. (2017). The bromodomain protein BRD4 regulates splicing during heat shock. Nucleic Acids Res., 45 (1). S. 382 - 395. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Isensee, Joerg ORCID: 0000-0002-3390-0051, Diskar, Mandy, Waldherr, Steffen ORCID: 0000-0002-0936-579X, Buschow, Rene ORCID: 0000-0002-9800-2578, Hasenauer, Jan ORCID: 0000-0002-4935-3312, Prinz, Anke, Allgoewer, Frank, Herberg, Friedrich W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2014). Pain modulators regulate the dynamics of PKA-RII phosphorylation in subgroups of sensory neurons. J. Cell Sci., 127 (1). S. 216 - 230. CAMBRIDGE: COMPANY OF BIOLOGISTS LTD. ISSN 1477-9137

Isensee, Joerg ORCID: 0000-0002-3390-0051, Kaufholz, Melanie, Knape, Matthias J., Hasenauer, Jan ORCID: 0000-0002-4935-3312, Hammerich, Hanna, Gonczarowska-Jorge, Humberto, Zahedi, Rene P., Schwede, Frank, Herberg, Friedrich W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2018). PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination. J. Cell Biol., 217 (6). S. 2167 - 2185. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-8140

Isensee, Joerg ORCID: 0000-0002-3390-0051, Krahe, Leonhardt, Moeller, Katharina, Pereira, Vanessa ORCID: 0000-0001-5416-6856, Sexton, Jane E., Sun, Xiaohui, Emery, Edward ORCID: 0000-0001-9723-8661, Wood, John N. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2017). Synergistic regulation of serotonin and opioid signaling contribute to pain insensitivity in Na(v)1.7 knockout mice. Sci. Signal., 10 (461). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1937-9145

Isensee, Joerg ORCID: 0000-0002-3390-0051, Schild, Cosimo, Schwede, Frank ORCID: 0000-0002-8185-3392 and Hucho, Tim ORCID: 0000-0002-4147-9308 (2017). Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging. J. Cell Sci., 130 (13). S. 2134 - 2147. CAMBRIDGE: COMPANY BIOLOGISTS LTD. ISSN 1477-9137

Isensee, Joerg ORCID: 0000-0002-3390-0051, Wenzel, Carsten, Buschow, Rene ORCID: 0000-0002-9800-2578, Weissmann, Robert, Kuss, Andreas W. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2014). Subgroup-Elimination Transcriptomics Identifies Signaling Proteins that Define Subclasses of TRPV1-Positive Neurons and a Novel Paracrine Circuit. PLoS One, 9 (12). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Isensee, Joerg, van Cann, Marianne, Despang, Patrick ORCID: 0000-0002-5258-3653, Araldi, Dioneia ORCID: 0000-0001-8379-2901, Moeller, Katharina, Petersen, Jonas, Schmidtko, Achim, Matthes, Jan ORCID: 0000-0003-2754-1555, Levine, Jon D. and Hucho, Tim ORCID: 0000-0002-4147-9308 (2021). Depolarization induces nociceptor sensitization by Ca(V)1.2-mediated PKA-II activation. J. Cell Biol., 220 (10). NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-8140

Jachimowicz, Ron D., Beleggia, Filippo ORCID: 0000-0003-0234-7094, Isensee, Joerg ORCID: 0000-0002-3390-0051, Velpula, Bhagya Bhavana, Goergens, Jonas, Bustos, Matias A., Doll, Markus A., Shenoy, Anjana, Checa-Rodriguez, Cintia, Wiederstein, Janica Lea, Baranes-Bachar, Keren, Bartenhagen, Christoph, Hertwig, Falk ORCID: 0000-0003-4784-6516, Teper, Nizan, Nishi, Tomohiko, Schmitt, Anna, Distelmaier, Felix, Luedecke, Hermann-Josef, Albrecht, Beate, Krueger, Marcus ORCID: 0000-0003-2008-4582, Schumacher, Bjorn ORCID: 0000-0001-6097-5238, Geiger, Tamar, Hoon, Dave S. B., Huertas, Pablo ORCID: 0000-0002-1756-4449, Fischer, Matthias, Hucho, Tim, Peifer, Martin, Ziv, Yael, Reinhardt, H. Christian, Wieczorek, Dagmar and Shiloh, Yosef (2019). UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell, 176 (3). S. 505 - 542. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Kaehler, Christian, Isensee, Joerg ORCID: 0000-0002-3390-0051, Hucho, Tim ORCID: 0000-0002-4147-9308, Lehrach, Hans and Krobitsch, Sylvia (2014). 5-Fluorouracil affects assembly of stress granules based on RNA incorporation. Nucleic Acids Res., 42 (10). S. 6436 - 6448. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Kaehler, Christian, Isensee, Joerg ORCID: 0000-0002-3390-0051, Nonhoff, Ute, Terrey, Markus ORCID: 0000-0002-7359-4810, Hucho, Tim ORCID: 0000-0002-4147-9308, Lehrach, Hans and Krobitsch, Sylvia (2012). Ataxin-2-Like Is a Regulator of Stress Granules and Processing Bodies. PLoS One, 7 (11). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Kanne, Julian, Hussong, Michelle, Isensee, Joerg, Munoz-Lopez, Alvaro, Wolffgramm, Jan, Hess, Felix, Grimm, Christina ORCID: 0000-0002-4676-8870, Bessonov, Sergey, Meder, Lydia, Wang, Jie, Reinhardt, H. Christian, Odenthal, Margarete, Hucho, Tim ORCID: 0000-0002-4147-9308, Buettner, Reinhard, Summerer, Daniel and Schweiger, Michal R. (2021). Pericentromeric Satellite III transcripts induce etoposide resistance. Cell Death Dis., 12 (6). LONDON: SPRINGERNATURE. ISSN 2041-4889

Lechner, Axel, Schloesser, Hans, Rothschild, Sacha I., Thelen, Martin ORCID: 0000-0002-2785-9726, Reuter, Sabrina, Zentis, Peter, Shimabukuro-Vornhagen, Alexander, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Wennhold, Kerstin ORCID: 0000-0001-5539-7226, Garcia-Marquez, Maria, Tharun, Lars, Quaas, Alexander, Schauss, Astrid, Isensee, Joerg ORCID: 0000-0002-3390-0051, Hucho, Tim ORCID: 0000-0002-4147-9308, Huebbers, Christian ORCID: 0000-0002-2934-1218, von Bergwelt-Baildon, Michael and Beutner, Dirk (2017). Characterization of tumor-associated T-lymphocyte subsets and immune checkpoint molecules in head and neck squamous cell carcinoma. Oncotarget, 8 (27). S. 44418 - 44434. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Loeser, Johannes, Layer, Brigitte, Plata, Christopher, Perrar, Klaus-Maria, Hucho, Tim and Kulbida, Rebecca (2020). Hirudotherapy attenuates arthritic pain in patients with various chronic pain syndromes: A retrospective analysis. J. Integr. Med.-JIM, 18 (5). S. 425 - 434. AMSTERDAM: ELSEVIER. ISSN 2095-4964

Loos, Carolin ORCID: 0000-0003-3680-0627, Moeller, Katharina, Froehlich, Fabian, Hucho, Tim ORCID: 0000-0002-4147-9308 and Hasenauer, Jan ORCID: 0000-0002-4935-3312 (2018). A Hierarchical, Data-Driven Approach to Modeling Single-Cell Populations Predicts Latent Causes of Cell-To-Cell Variability. Cell Syst., 6 (5). S. 593 - 617. CAMBRIDGE: CELL PRESS. ISSN 2405-4720

Mettler, Jasmin, Drzezga, Alexander ORCID: 0000-0001-6018-716X, Dietlein, Markus, Hucho, Tim ORCID: 0000-0002-4147-9308 and Kobe, Carsten (2021). Prostate-Specific Membrane Antigen Uptake in a Peripheral Nerve and Respective Ganglia on Ga-68-Prostate-Specific Membrane Antigen-HBED-CC PET/CT. Clin. Nucl. Med., 46 (1). S. 69 - 71. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-0229

Muke, Ines, Isensee, Joerg, Imhof, Thomas, Wiesen, Martin, Wassermann, Meike, Mueller, Carsten, Hucho, Tim, Koch, Manuel and Lehmann, Helmar ORCID: 0000-0001-6205-2293 (2020). New insights into the active transport of paclitaxel into the sensory neuron. J. Peripher. Nerv. Syst., 25 (4). S. 521 - 522. HOBOKEN: WILEY. ISSN 1529-8027

Overhoff, Melina ORCID: 0000-0002-4208-8632, Tellkamp, Frederik ORCID: 0000-0002-0473-7320, Hess, Simon ORCID: 0000-0001-6085-5156, Tolve, Marianna ORCID: 0000-0002-0893-2967, Tutas, Janine, Faerfers, Marcel, Ickert, Lotte, Mohammadi, Milad ORCID: 0000-0003-1755-108X, De Bruyckere, Elodie, Kallergi, Emmanouela, Delle Vedove, Andrea, Nikoletopoulou, Vassiliki, Wirth, Brunhilde ORCID: 0000-0003-4051-5191, Isensee, Joerg, Hucho, Tim ORCID: 0000-0002-4147-9308, Puchkov, Dmytro, Isbrandt, Dirk ORCID: 0000-0002-4720-1016, Krueger, Marcus, Kloppenburg, Peter and Kononenko, Natalia L. (2022). Autophagy regulates neuronal excitability by controlling cAMP/protein kinase A signaling at the synapse. Embo J., 41 (22). HOBOKEN: WILEY. ISSN 1460-2075

Ratz, Leonie, Brambillasca, Chiara, Bartke, Leandra, Huetzen, Maxim A., Goergens, Jonas, Leidecker, Orsolya, Jachimowicz, Ron D., van de Ven, Marieke, Proost, Natalie, Siteur, Bjorn, de Korte-Grimmerink, Renske, Bouwman, Peter ORCID: 0000-0002-9252-5896, Pulver, Emilia M., de Bruijn, Roebi, Isensee, Joerg, Hucho, Tim ORCID: 0000-0002-4147-9308, Pandey, Gaurav, van Lohuizen, Maarten, Mallmann, Peter, Reinhardt, Hans Christian, Jonkers, Jos ORCID: 0000-0002-9264-9792 and Puppe, Julian (2022). Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer. Breast Cancer Res., 24 (1). LONDON: BMC. ISSN 1465-542X

Schmidt, Julia ORCID: 0000-0002-5942-2924, Goergens, Jonas, Pochechueva, Tatiana, Kotter, Annika, Schwenzer, Niko, Sitte, Maren, Werner, Gesa, Altmueller, Janine, Thiele, Holger, Nuernberg, Peter, Isensee, Joerg, Li, Yun, Mueller, Christian, Leube, Barbara, Reinhardt, H. Christian, Hucho, Tim ORCID: 0000-0002-4147-9308, Salinas, Gabriela, Helm, Mark, Jachimowicz, Ron D., Wieczorek, Dagmar, Kohl, Tobias, Lehnart, Stephan E., Yigit, Goekhan and Wollnik, Bernd ORCID: 0000-0003-2589-0364 (2021). Biallelic variants in YRDC cause a developmental disorder with progeroid features. Hum. Genet., 140 (12). S. 1679 - 1694. NEW YORK: SPRINGER. ISSN 1432-1203

Schroeder, Daniel C., Maul, Alexandra C., Mahabir, Esther, Koxholt, Isabell, Yan, Xiaowei, Padosch, Stephan A., Herff, Holger, Bultmann-Mellin, Insa, Sterner-Kock, Anja, Annecke, Thorsten ORCID: 0000-0002-2496-4432, Hucho, Tim ORCID: 0000-0002-4147-9308, Boettiger, Bernd W. and Guschlbauer, Maria ORCID: 0000-0002-5401-4542 (2018). Evaluation of small intestinal damage in a rat model of 6 Minutes cardiac arrest. BMC Anesthesiol., 18. LONDON: BIOMED CENTRAL LTD. ISSN 1471-2253

Schroeder, Daniel C., Popp, Erik, Rohleder, Cathrin ORCID: 0000-0002-3559-1846, Vus, Stefanie, Bethencourt, David de la Puente, Finke, Simon R., Zlatopolskiy, Boris D., Zischler, Johannes, Drzezga, Alexander ORCID: 0000-0001-6018-716X, Herff, Holger, Annecke, Thorsten, Hucho, Tim ORCID: 0000-0002-4147-9308, Neumaier, Bernd, Boettiger, Bernd W. and Endepols, Heike (2021). Positron Emission Tomography Imaging of Long-Term Expression of the 18 kDa Translocator Protein After Sudden Cardiac Arrest in Rats. Shock, 55 (5). S. 620 - 630. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1540-0514

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Wabnig, Florian, Schroeder, Daniel, Guschlbauer, Maria, Hucho, Tim ORCID: 0000-0002-4147-9308, Koch, Konrad R., Cursiefen, Claus and Heindl, Ludwig M. (2015). Effect of global ischemia/reperfusion on the retina in a rat model of cardiac arrest. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Yang, Nicole J., Isensee, Joerg, Neel, Dylan, V, Quadros, Andreza U., Zhang, Han-Xiong Bear, Lauzadis, Justas, Liu, Sai Man ORCID: 0000-0001-6359-0229, Shiers, Stephanie, Belu, Andreea, Palan, Shilpa, Marlin, Sandra, Maignel, Jacquie, Kennedy-Curran, Angela, Tong, Victoria S., Moayeri, Mahtab, Roederer, Pascal, Nitzsche, Anja, Lu, Mike, Pentelute, Bradley L., Bruestle, Oliver, Tripathi, Vineeta, Foster, Keith A., Price, Theodore J., Collier, R. John, Leppla, Stephen H., Puopolo, Michelino, Bean, Bruce P., Cunha, Thiago M., Hucho, Tim and Chiu, Isaac M. . Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2(+) DRG sensory neurons. Nat. Neurosci.. BERLIN: NATURE PORTFOLIO. ISSN 1546-1726

van Cann, Marianne, Kuzmenkov, Alexey, Isensee, Jorg, Andreev-Andrievskiy, Alexander ORCID: 0000-0002-1173-8153, Peigneur, Steve, Khusainov, Georgii, Berkut, Antonina, Tytgat, Jan, Vassilevski, Alexander ORCID: 0000-0002-1359-0076 and Hucho, Tim . Scorpion toxin MeuNaTx alpha-1 sensitizes primary nociceptors by selective modulation of voltage-gated sodium channels. FEBS J.. HOBOKEN: WILEY. ISSN 1742-4658

von Reumont, Bjoern M., Anderluh, Gregor, Antunes, Agostinho, Ayvazyan, Naira, Beis, Dimitris, Caliskan, Figen, Crnkovic, Ana ORCID: 0000-0002-0581-1887, Damm, Maik ORCID: 0000-0003-0810-3699, Dutertre, Sebastien, Ellgaard, Lars ORCID: 0000-0002-7018-0137, Gajski, Goran, German, Hannah, Halassy, Beata, Hempel, Benjamin-Florian ORCID: 0000-0002-1998-4033, Hucho, Tim ORCID: 0000-0002-4147-9308, Igci, Nasit, Ikonomopoulou, Maria P., Karbat, Izhar, Klapa, Maria, I, Koludarov, Ivan, Kool, Jeroen, Lueddecke, Tim, Ben Mansour, Riadh, Modica, Maria Vittoria, Moran, Yehu, Nalbantsoy, Ayse, Pachon Ibanez, Maria Eugenia, Panagiotopoulos, Alexios, Reuveny, Eitan, Sanchez Cespedes, Javier, Sombke, Andy ORCID: 0000-0001-7383-440X, Surm, Joachim M., Undheim, Eivind A. B., Verdes, Aida ORCID: 0000-0002-9193-9253 and Zancolli, Giulia ORCID: 0000-0003-3060-2507 (2022). Modern venomics-Current insights, novel methods, and future perspectives in biological and applied animal venom research. GigaScience, 11. OXFORD: OXFORD UNIV PRESS. ISSN 2047-217X