Universität zu Köln

Journal Article

Bebber, Christina M., Thomas, Emily S., Stroh, Jenny, Chen, Zhiyi, Androulidaki, Ariadne, Schmitt, Anna, Hoehne, Michaela N., Stueker, Lukas, Alves, Cleidson de Padua, Khonsari, Armin, Dammert, Marcel A., Parmaksiz, Fatma, Tumbrink, Hannah L., Beleggia, Filippo ORCID: 0000-0003-0234-7094, Sos, Martin L., Riemer, Jan, George, Julie, Brodesser, Susanne, Thomas, Roman K., Reinhardt, H. Christian and von Karstedt, Silvia (2021). Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat. Commun., 12 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723

Braegelmann, Johannes, Boehm, Stefanie, Guthrie, Matthew R., Mollaoglu, Gurkan ORCID: 0000-0003-0679-7463, Oliver, Trudy G. and Sos, Martin L. (2017). Family matters: How MYC family oncogenes impact small cell lung cancer. Cell Cycle, 16 (16). S. 1489 - 1499. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1551-4005

Braegelmann, Johannes, Dammert, Marcel A., Dietlein, Felix, Heuckmann, Johannes M., Choidas, Axel, Boehm, Stefanie, Richters, Andre, Basu, Debjit, Tischler, Verena ORCID: 0000-0002-6673-8329, Lorenz, Carina, Habenberger, Peter, Fang, Zhizhou, Ortiz-Cuaran, Sandra, Leenders, Frauke, Eickhoff, Jan, Koch, Uwe, Getlik, Matthaeus, Termathe, Martin ORCID: 0000-0002-5618-4633, Sallouh, Muhammad, Greff, Zoltan, Varga, Zoltan, Balke-Want, Hyatt, French, Christopher A., Peifer, Martin ORCID: 0000-0002-5243-5503, Reinhardt, H. Christian, Orfi, Laszlo ORCID: 0000-0001-6149-2385, Keri, Gyorgy, Ansen, Sascha, Heukamp, Lukas C., Buettner, Reinhard, Rauh, Daniel, Klebl, Bert M., Thomas, Roman K. and Sos, Martin L. (2017). Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma. Cell Reports, 20 (12). S. 2833 - 2846. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Braegelmann, Johannes, Lorenz, Carina, Borchmann, Sven ORCID: 0000-0001-6662-6864, Nishii, Kazuya, Wegner, Julia ORCID: 0000-0001-8103-8040, Meder, Lydia, Ostendorp, Jenny, Ast, David F., Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A., Plenker, Dennis, Klein, Sebastian ORCID: 0000-0002-2188-9377, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K., Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S., Li, Henry, Schmitt, Clemens A. ORCID: 0000-0002-4731-2226, George, Julie, Thomas, Roman K., von Karstedt, Silvia, Hartmann, Gunther, Buettner, Reinhard, Ullrich, Roland T., Siveke, Jens T., Ohashi, Kadoaki, Schlee, Martin ORCID: 0000-0003-3671-7639 and Sos, Martin L. (2021). MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nat. Commun., 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Buettner, Reinhard, Wolf, Juergen, Thomas, Roman K. and Sos, Martin L. (2017). Resistance Mechanisms to AZD9291 and Rociletinib-Response. Clin. Cancer Res., 23 (14). S. 3967 - 3969. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Dammed, Marcel A., Bragelmann, Johannes, Olsen, Rachelle R., Boehm, Stefanie, Monhasery, Niloufar, Whitney, Christopher P., Chalishazar, Milind D., Tumbrink, Hannah L., Guthrie, Matthew R., Klein, Sebastian, Irelands, Abbie S., Ryan, Jeremy, Schmitt, Anna, Marx, Annika, Ozretic, Luka, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Lorenz, Carina, Jachimowicz, Ron D., Wolf, Elmar ORCID: 0000-0002-5299-6335, Thomas, Roman K., Poirier, John T., Buettner, Reinhard, Sen, Triparna, Byers, Lauren A., Reinhardt, H. Christian, Letai, Anthony, Oliver, Trudy G. and Sos, Martin L. (2019). MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Dammert, Marcel A. and Sos, Martin L. (2018). Endogenous, CRISPR-mediated overexpression of MYC family members as a framework to discover MYC-specific vulnerabilities. Cancer Res., 78 (13). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Engel, Julian, Richters, Andre, Getlik, Matthaeus, Tomassi, Stefano, Keul, Marina, Termathe, Martin ORCID: 0000-0002-5618-4633, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Becker, Christian, Mayer-Wrangowski, Svenja, Gruetter, Christian, Uhlenbrock, Niklas ORCID: 0000-0002-4489-9535, Kruell, Jasmin, Schaumann, Niklas, Eppmann, Simone, Kibies, Patrick, Hoffgaard, Franziska, Heil, Jochen, Menninger, Sascha, Ortiz-Cuaran, Sandra, Heuckmann, Johannes M., Tinnefeld, Verena, Zahedi, Rene P., Sos, Martin L., Schultz-Fademrecht, Carsten, Thomas, Roman K., Kast, Stefan M. and Rauh, Daniel ORCID: 0000-0002-1970-7642 (2015). Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. J. Med. Chem., 58 (17). S. 6844 - 6864. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Fassunke, Jana, Mueller, Fabienne, Keul, Marina, Michels, Sebastian, Dammert, Marcel A., Schmitt, Anna, Plenker, Dennis, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Heydt, Carina, Braegelmann, Johannes, Tumbrink, Hannah L., Alber, Yannic, Klein, Sebastian, Heimsoeth, Alena, Dahmen, Ilona, Fischers, Rieke N., Scheffler, Matthias, Ihle, Michaela A., Priesner, Vanessa, Scheel, Andreas H., Wagener, Svenja, Kron, Anna, Frank, Konrad, Garbert, Katia, Persigehl, Thorsten, Puesken, Michael, Haneder, Stefan, Schaaf, Bernhard, Rodermann, Ernst, Engel-Riedel, Walburga, Felip, Enriqueta, Smit, Egbert F., Merkelbach-Bruse, Sabine, Reinhardt, H. Christian, Kast, Stefan M., Wolf, Juergen, Rauh, Daniel, Buettner, Reinhard and Sos, Martin L. (2018). Overcoming EGFR(G724S)-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

French, Christopher A., Cheng, Michael L., Hanna, Glenn J., DuBois, Steven G., Chau, Nicole G., Hann, Christine L., Storck, Simone, Salgia, Ravi, Trucco, Matteo, Tseng, Jennifer, Stathis, Anastasios, Piekarz, Richard, Lauer, Ulrich M., Massard, Christophe, Bennett, Kelly, Coker, Shodeinde, Tontsch-Grunt, Ulrike, Sos, Martin L., Liao, Sida, Wu, Catherine J., Polyak, Kornelia, Piha-Paul, Sarina A. and Shapiro, Geoffrey I. (2022). Report of the First International Symposium on NUT Carcinoma. Clin. Cancer Res., 28 (12). S. 2493 - 2506. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Heuckmann, Johannes M., Hoelzel, Michael, Sos, Martin L., Heynck, Stefanie, Balke-Want, Hyatt, Koker, Mirjam, Peifer, Martin ORCID: 0000-0002-5243-5503, Weiss, Jonathan, Lovly, Christine M., Gruetter, Christian, Rauh, Daniel ORCID: 0000-0002-1970-7642, Pao, William and Thomas, Roman K. (2011). ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors. Clin. Cancer Res., 17 (23). S. 7394 - 7402. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1078-0432

Hoepker, Katja, Hagmann, Henning, Khurshid, Safiya, Chen, Shuhua, Hasskamp, Pia, Seeger-Nukpezah, Tamina, Schilberg, Katharina, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Lamkemeyer, Tobias, Sos, Martin L., Thomas, Roman K., Lowery, Drew, Roels, Frederik, Fischer, Matthias, Liebau, Max C., Resch, Ulrike ORCID: 0000-0002-8380-9555, Kisner, Tuelay, Roether, Fabian, Bartram, Malte P., Mueller, Roman Ulrich, Fabretti, Francesca, Kurschat, Peter, Schumacher, Bjoern, Gaestel, Matthias ORCID: 0000-0002-4944-4652, Medema, Rene H., Yaffe, Michael B., Schermer, Bernhard ORCID: 0000-0002-5194-9000, Reinhardt, H. Christian and Benzing, Thomas (2012). AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. Embo J., 31 (20). S. 3961 - 3976. HOBOKEN: WILEY. ISSN 1460-2075

Koenig, Katharina, Peifer, Martin ORCID: 0000-0002-5243-5503, Fassunke, Jana, Ihle, Michaela A., Kuenstlinger, Helen, Heydt, Carina, Stamm, Katrin, Ueckeroth, Frank, Vollbrecht, Claudia ORCID: 0000-0002-0861-001X, Bos, Marc, Gardizi, Masyar, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Nogova, Lucia, Leenders, Frauke, Albus, Kerstin, Meder, Lydia ORCID: 0000-0002-9547-5812, Becker, Kerstin, Florin, Alexandra, Rommerscheidt-Fuss, Ursula, Altmueller, Janine, Kloth, Michael, Nuernberg, Peter, Henkel, Thomas, Bikar, Sven-Ernoe, Sos, Martin L., Geese, William J., Strauss, Lewis, Ko, Yon-Dschun, Gerigk, Ulrich, Odenthal, Margarete, Zander, Thomas, Wolf, Juergen, Merkelbach-Bruse, Sabine, Buettner, Reinhard and Heukamp, Lukas C. (2015). Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients. J. Thorac. Oncol., 10 (7). S. 1049 - 1058. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1556-1380

Lategahn, Jonas, Tumbrink, Hannah L., Schultz-Fademrecht, Carsten, Heimsoeth, Alena, Werr, Lisa ORCID: 0000-0002-3697-4136, Niggenaber, Janina, Keul, Marina, Parmaksiz, Fatma ORCID: 0009-0003-3771-7128, Baumann, Matthias, Menninger, Sascha, Zent, Eldar, Landel, Ina, Weisner, Joern, Jeyakumar, Kirujan ORCID: 0000-0002-0184-6775, Heyden, Leonie, Russ, Nicole, Mueller, Fabienne, Lorenz, Carina, Braegelmann, Johannes, Spille, Inga, Grabe, Tobias ORCID: 0000-0002-8287-1971, Mueller, Matthias P., Heuckmann, Johannes M., Klebl, Bert M., Nussbaumer, Peter, Sos, Martin L. and Rauh, Daniel (2022). Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors. J. Med. Chem., 65 (9). S. 6643 - 6656. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Malchers, Florian, Ercanoglu, Meryem, Schuette, Daniel ORCID: 0000-0002-4746-537X, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Tischler, Verena ORCID: 0000-0002-6673-8329, Michels, Sebastian, Dahmen, Ilona, Braegelmann, Johannes, Menon, Roopika, Heuckmann, Johannes M., George, Julie, Ansen, Sascha, Sos, Martin L., Soltermann, Alex, Peifer, Martin ORCID: 0000-0002-5243-5503, Wolf, Juergen, Buettner, Reinhard and Thomas, Roman K. (2017). Mechanisms of Primary Drug Resistance in FGFR1-Amplified Lung Cancer. Clin. Cancer Res., 23 (18). S. 5527 - 5537. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Michels, Sebastian, Heydt, Carina, van Veggel, Bianca, Deschler-Baier, Barbara, Pardo, Nuria, Monkhorst, Kim, Ruesseler, Vanessa, Stratmann, Jan, Griesinger, Frank, Steinhauser, Susanne, Kostenko, Anna, Diebold, Joachim, Fassunke, Jana, Fischer, Rieke, Engel-Riedel, Walburga, Gautschi, Oliver, Geissinger, Eva, Haneder, Stefan, Ihle, Michaela A., Kopp, Hans-Georg, de Langen, Adrianus J., Martinez-Marti, Alex, Nogova, Lucia, Persigehl, Thorsten, Plenker, Dennis, Puesken, Michael, Rodermann, Ernst, Rosenwald, Andreas, Scheel, Andreas H., Scheffler, Matthias, Spengler, Werner, Seggewiss-Bernhardt, Ruth, Braegelmann, Johannes, Sebastian, Martin, Vrugt, Bart, Hellmich, Martin, Sos, Martin L., Heukamp, Lukas C., Felip, Enriqueta, Merkelbach-Bruse, Sabine, Smit, Egbert F., Buettner, Reinhard and Wolf, Juergen (2019). Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer. JCO Precis. Oncol., 3. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 2473-4284

Michels, Sebastian, Scheffler, Matthias, Wagener, Svenja, Plenker, Dennis, Scheel, Andreas, Nogova, Lucia, Schultheis, Anne, Fischer, Rieke N., Abdulla, Diana S. Y., Riedel, Richard, Bunck, Anne, Kobe, Carsten, Baus, Wolfgang, Merkelbach-Bruse, Sabine, Sos, Martin L., Buttner, Reinhard and Wolf, Jurgen (2018). Loss of G2032R Resistance Mutation Upon Chemotherapy Treatment Enables Successful Crizotinib Rechallenge in a Patient With ROS1-Rearranged NSCLC. JCO Precis. Oncol., 2. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 2473-4284

Mollaoglu, Gurkan ORCID: 0000-0003-0679-7463, Guthrie, Matthew R., Boehm, Stefanie, Braegelmann, Johannes, Can, Ismail, Ballieu, Paul M., Marx, Annika, George, Julie, Heinen, Christine, Chalishazar, Milind D., Cheng, Haixia, Ireland, Abbie S., Denning, Kendall E., Mukhopadhyay, Anandaroop, Vahrenkamp, Jeffery M., Berrett, Kristofer C., Mosbruger, Timothy L., Wang, Jun, Kohan, Jessica L., Salama, Mohamed E., Witt, Benjamin L., Peifer, Martin ORCID: 0000-0002-5243-5503, Thomas, Roman K., Gertz, Jason ORCID: 0000-0001-7568-6789, Johnson, Jane E., Gazdar, Adi F., Wechsler-Reya, Robert J., Sos, Martin L. and Oliver, Trudy G. (2017). MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition. Cancer Cell, 31 (2). S. 270 - 286. CAMBRIDGE: CELL PRESS. ISSN 1878-3686

Nogova, Lucia, Mattonet, Christian, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Taubert, Max ORCID: 0000-0001-8925-7782, Gardizi, Masyar, Sos, Martin L., Michels, Sebastian, Fischer, Rieke N., Limburg, Meike, Abdulla, Diana S. Y., Persigehl, Thorsten, Kobe, Carsten, Merkelbach-Bruse, Sabine, Franklin, Jeremy, Backes, Heiko, Schnell, Roland, Behringer, Dirk, Kaminsky, Britta, Eichstaedt, Martina, Stelzer, Christoph, Kinzig, Martina, Soergel, Fritz, Tian, Yingying, Junge, Lisa, Suleiman, Ahmed A., Frechen, Sebastian, Rokitta, Dennis, Ouyang, Dongsheng, Fuhr, Uwe, Buettner, Reinhard and Wolf, Juergen (2020). Sorafenib and everolimus in patients with advanced solid tumors and KRAS-mutated NSCLC: A phase I trial with early pharmacodynamic FDG-PET assessment. Cancer Med., 9 (14). S. 4991 - 5008. HOBOKEN: WILEY. ISSN 2045-7634

Ortiz-Cuaran, Sandra, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Lovly, Christine M., Bos, Marc, Scheffler, Matthias, Michels, Sebastian, Albus, Kerstin, Meyer, Lydia, Koenig, Katharina, Dahmen, Ilona, Mueller, Christian, Ozretic, Luca, Tharun, Lars, Schaub, Philipp, Florin, Alexandra, Pinther, Berit, Bahlmann, Nike, Ansen, Sascha, Peifer, Martin, Heukamp, Lukas C., Buettner, Reinhard, Sos, Martin L., Wolf, Juergen, Pao, William and Thomas, Roman K. (2015). Elucidating the mechanisms of acquired resistance in lung adenocarcinomas. Cancer Res., 75. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Ortiz-Cuaran, Sandra, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Plenker, Dennis, Dahmen, Ilona, Scheel, Andreas H., Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Meder, Lydia ORCID: 0000-0002-9547-5812, Lovly, Christine M., Persigehl, Thorsten, Merkelbach-Bruse, Sabine, Bos, Marc, Michels, Sebastian, Fischer, Rieke, Albus, Kerstin, Koenig, Katharina, Schildhaus, Hans-Ulrich, Fassunke, Jana, Ihle, Michaela A., PasternackO, Helen, Heydt, Carina, Becker, Christian, Altmueller, Janine, Ji, Hongbin, Mueller, Christian, Florin, Alexandra, Heuckmann, Johannes M., Nuernberg, Peter, Ansen, Sascha, Heukamp, Lukas C., Berg, Johannes, Pao, William, Peifer, Martin ORCID: 0000-0002-5243-5503, Buettner, Reinhard, Wolfe, Juergen, Thomas, Roman K. and Sos, Martin L. (2016). Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors. Clin. Cancer Res., 22 (19). S. 4837 - 4848. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Park, Kwon-Sik, Martelotto, Luciano G., Peifer, Martin ORCID: 0000-0002-5243-5503, Sos, Martin L., Karnezis, Anthony N., Mahjoub, Moe R., Bernard, Katie, Conklin, Jamie F., Szczepny, Anette, Yuan, Jing, Guo, Ribo, Ospina, Beatrice, Falzon, Jeanette, Bennett, Samara, Brown, Tracey J., Markovic, Ana, Devereux, Wendy L., Ocasio, Cory A., Chen, James K., Stearns, Tim ORCID: 0000-0002-0671-6582, Thomas, Roman K., Dorsch, Marion, Buonamici, Silvia, Watkins, D. Neil, Peacock, Craig D. and Sage, Julien (2011). A crucial requirement for Hedgehog signaling in small cell lung cancer. Nat. Med., 17 (11). S. 1504 - 1510. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-170X

Peifer, Martin ORCID: 0000-0002-5243-5503, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Sos, Martin L., George, Julie, Seidel, Danila ORCID: 0000-0003-4388-3117, Kasper, Lawryn H., Plenker, Dennis, Leenders, Frauke, Sun, Ruping, Zander, Thomas, Menon, Roopika, Koker, Mirjam, Dahmen, Ilona, Mueller, Christian, Di Cerbo, Vincenzo ORCID: 0000-0002-2920-1274, Schildhaus, Hans-Ulrich, Altmueller, Janine, Baessmann, Ingelore, Becker, Christian, de Wilde, Bram, Vandesompele, Jo ORCID: 0000-0001-6274-0184, Boehm, Diana, Ansen, Sascha, Gabler, Franziska, Wilkening, Ines, Heynck, Stefanie, Heuckmann, Johannes M., Lu, Xin, Carter, Scott L., Cibulskis, Kristian, Banerji, Shantanu, Getz, Gad, Park, Kwon-Sik, Rauh, Daniel ORCID: 0000-0002-1970-7642, Gruetter, Christian, Fischer, Matthias, Pasqualucci, Laura, Wright, Gavin ORCID: 0000-0002-7000-9305, Wainer, Zoe, Russell, Prudence, Petersen, Iver, Chen, Yuan, Stoelben, Erich, Ludwig, Corinna, Schnabel, Philipp, Hoffmann, Hans, Muley, Thomas, Brockmann, Michael, Engel-Riedel, Walburga, Muscarella, Lucia A., Fazio, Vito M., Groen, Harry, Timens, Wim ORCID: 0000-0002-4146-6363, Sietsma, Hannie, Thunnissen, Erik ORCID: 0000-0001-5355-8508, Smit, Egbert, Heideman, Danielle A. M., Snijders, Peter J. F., Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John, Solberg, Steinar, Brustugun, Odd Terje, Lund-Iversen, Marius, Saenger, Joerg, Clement, Joachim H. ORCID: 0000-0002-6601-2456, Soltermann, Alex, Moch, Holger, Weder, Walter, Solomon, Benjamin, Soria, Jean-Charles, Validire, Pierre, Besse, Benjamin ORCID: 0000-0001-5090-8189, Brambilla, Elisabeth, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Schneider, Peter M. ORCID: 0000-0003-0744-2349, Hallek, Michael, Pao, William, Meyerson, Matthew ORCID: 0000-0002-9133-8108, Sage, Julien, Shendure, Jay ORCID: 0000-0002-1516-1865, Schneider, Robert, Buettner, Reinhard, Wolf, Juergen, Nuernberg, Peter, Perner, Sven, Heukamp, Lukas C., Brindle, Paul K., Haas, Stefan ORCID: 0000-0003-3418-3688 and Thomas, Roman K. (2012). Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nature Genet., 44 (10). S. 1104 - 1113. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-1718

Plenker, Dennis, Bertrand, Miriam, de Langen, Adrianus J., Riedel, Richard, Lorenz, Carina, Scheel, Andreas H., Mueller, Judith, Braegelmann, Johannes, Dassler-Plenker, Juliane, Kobe, Carsten, Persigehl, Thorsten, Kluge, Alexander, Wurdinger, Thomas, Schellen, Pepijn, Hartmann, Gunther ORCID: 0000-0003-1021-2018, Zacherle, Tobias, Menon, Roopika, Thunnissen, Erik, Buettner, Reinhard, Griesinger, Frank, Wolf, Juergen, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Sos, Martin L. and Heuckmann, Johannes M. (2018). Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients. Clin. Cancer Res., 24 (6). S. 1337 - 1344. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Plenker, Dennis, Lorenz, Carina, Bertrand, Miriam, Riedel, Richard, de Langen, Joop, Braegelmann, Johannes, Buettner, Reinhard, Wolf, Juergen, Thomas, Roman K., Heuckmann, Johannes and Sos, Martin L. (2018). Targeting structural RET and MET kinase alterations in lung adenocarcinoma patients. Cancer Res., 78 (13). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Plenker, Dennis, Riedel, Maximilian, Braegelmann, Johannes, Dammert, Marcel A., Chauhan, Rakhee, Knowles, Phillip P., Lorenz, Carina, Keul, Marina, Buehrmann, Mike, Pagel, Oliver, Tischler, Verena ORCID: 0000-0002-6673-8329, Scheel, Andreas H., Schtte, Daniel, Song, Yanrui, Stark, Justina, Mrugalla, Florian ORCID: 0000-0002-6281-6051, Alber, Yannic, Richters, Andre, Engel, Julian, Leenders, Frauke, Heuckmann, Johannes M., Wolf, Juergen, Diebold, Joachim, Pall, Georg, Peifer, Martin ORCID: 0000-0002-5243-5503, Aerts, Maarten, Gevaert, Kris ORCID: 0000-0002-4237-0283, Zahedi, Rene P., Buettner, Reinhard, Shokat, Kevan M., McDonald, Neil Q., Kast, Stefan M., Gautschi, Oliver, Thomas, Roman K. and Sos, Martin L. (2017). Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Sci. Transl. Med., 9 (394). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Poirier, John T., George, Julie, Owonikoko, Taofeek K., Berns, Anton, Brambilla, Elisabeth, Byers, Lauren A., Carbone, David, Chen, Huanhuan J., Christensen, Camilla L., Dive, Caroline, Farago, Anna, Govindan, Ramaswamy, Hann, Christine, Hellmann, Matthew D., Horn, Leora, Johnson, Jane E., Ju, Young S., Kang, Sumin, Krasnow, Mark, Lee, James, Lee, Se-Hoon, Lehman, Jonathan, Lok, Benjamin, Lovly, Christine ORCID: 0000-0002-3641-6361, MacPherson, David, McFadden, David, Minna, John, Oser, Matthew, Park, Keunchil, Park, Kwon-Sik, Pommier, Yves, Quaranta, Vito, Ready, Neal, Sage, Julien, Scagliotti, Giorgio, Sos, Martin L., Sutherland, Kate D., Travis, William D., Vakoc, Christopher R., Wait, Sarah J., Wistuba, Ignacio, Wong, Kwok Kin, Zhang, Hua, Daigneault, Jillian, Wiens, Jacinta, Rudin, Charles M. and Oliver, Trudy G. (2020). New Approaches to SCLC Therapy: From the Laboratory to the Clinic. J. Thorac. Oncol., 15 (4). S. 520 - 541. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1556-1380

Schaufler, Diana, Ast, David F., Tumbrink, Hannah L., Abedpour, Nima, Maas, Lukas, Schwaebe, Ayla E., Spille, Inga, Lennartz, Stefanie, Fassunke, Jana, Aldea, Mihaela, Besse, Benjamin, Planchard, David, Nogova, Lucia, Michels, Sebastian, Kobe, Carsten, Persigehl, Thorsten, Westphal, Theresa, Koleczko, Sophia, Fischer, Rieke, Weber, Jan-Phillip, Altmueller, Janine, Thomas, Roman K., Merkelbach-Bruse, Sabine, Gautschi, Oliver, Mezquita, Laura, Buettner, Reinhard, Wolf, Juergen, Peifer, Martin, Braegelmann, Johannes, Scheffler, Matthias and Sos, Martin L. (2021). Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer. npj Precis. Oncol., 5 (1). BERLIN: NATURE PORTFOLIO. ISSN 2397-768X

Scheffier, Matthias, Boa, Marc Christiaan Allardt, Sos, Martin L., Heukamp, Lukas Carl, Nogova, Lucia, Koenig, Katharina, Gardizi, Masyar, Mattonet, Christian, Kahraman, Manz, Kobe, Ca, Boellaard, Ronald, Lammertsma, Adriaan A., Persigehl, Thorsten, Engel-Riedel, Walburga, Toepelt, Karin, Neumaier, Bernd, Buettner, Reinhard, Zander, Thomas and Wolf, Juergen (2014). MIMEB: A phase II trial to evaluate FDG-PET/FLT-PET, DCE-MRI and molecular biomarkers for early prediction of nonprogression in patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab. J. Clin. Oncol., 32 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Scheffler, Matthias, Gardizi, Masyar, Christiaan, Marc, Bos, Allardt, Nogova, Lucia, Michels, Sebastian, Persigehl, Thorsten, Sos, Martin L., Dletlein, Felix, Zander, Thomas and Wolf, Juergen (2014). BARIS: A phase I trial to evaluate the safety and tolerability of combined BIBF 1120 mid RAD001 in stolid tumors and to determine the maximum tolerated dose (MTD) of the combination. J. Clin. Oncol., 32 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Scheffler, Matthias, Ihle, Michaela A., Hein, Rebecca, Merkelbach-Bruse, Sabine, Braegelmann, Johannes, Scheel, Andreas H., Michels, Sebastian Yves Friedrich, Ueckeroth, Frank, Eisert, Anna, Gogl, Leonie, Frank, Rieke, Fischer, Rieke Nila, Koleczko, Sophia, Schaepers, Carsten, Kostenko, Anna, Kron, Florian, Hellmich, Martin, Sos, Martin L., Buettner, Reinhard and Wolf, Juergen (2016). Genetic heterogeneity of KRAS-mutated NSCLC: Co-occurrence of potentially targetable aberrations and evolutionary background. J. Clin. Oncol., 34 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Scheffler, Matthias, Ihle, Michaela A., Hein, Rebecca, Merkelbach-Bruse, Sabine, Scheel, Andreas H., Siemanowski, Janna, Braegelmann, Johannes, Kron, Anna, Abedpour, Nima, Ueckeroth, Frank, Schueller, Merle, Koleczko, Sophia, Michels, Sebastian, Fassunke, Jana, Pasternack, Helen, Heydt, Carina, Serke, Monika, Fischer, Rieke, Schulte, Wolfgang, Gerigk, Ulrich, Nogova, Lucia, Ko, Yon-Dschun, Abdulla, Diana S. Y., Riedel, Richard, Kambartel, Karl-Otto, Lorenz, Joachim, Sauerland, Imke, Randerath, Winfried, Kaminsky, Britta, Hagmeyer, Lars, Grohe, Christian, Eisert, Anna, Frank, Rieke, Gogl, Leonie, Schaepers, Carsten, Holzem, Alessandra, Hellmich, Martin, Thomas, Roman K., Peifer, Martin, Sos, Martin L., Buettner, Reinhard and Wolf, Juergen (2019). K-ras Mutation Subtypes in NSCLC and Associated Co-occuring Mutations in Other Oncogenic Pathways. J. Thorac. Oncol., 14 (4). S. 606 - 617. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1556-1380

Scheffler, Matthias ORCID: 0000-0002-9031-1368, Merkelbach-Bruse, Sabine, Bos, Marc, Fassunke, Jana, Gardizi, Masyar, Michels, Sebastian, Groneck, Laura, Schultheis, Anne M., Malchers, Florian, Leenders, Frauke, Kobe, Carsten, Koenig, Katharina, Heukamp, Lukas C., Sos, Martin L., Thomas, Roman K., Buettner, Reinhard and Wolf, Juergen (2015). Spatial Tumor Heterogeneity in Lung Cancer with Acquired Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance. J. Thorac. Oncol., 10 (6). S. E40 - 4. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1556-1380

Seidel, Danila ORCID: 0000-0003-4388-3117, Zander, Thomas, Heukamp, Lukas C., Peifer, Martin ORCID: 0000-0002-5243-5503, Bos, Marc, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Leenders, Frauke, Lu, Xin, Ansen, Sascha, Gardizi, Masyar, Nguyen, Chau, Berg, Johannes, Russell, Prudence, Wainer, Zoe, Schildhaus, Hans-Ulrich, Rogers, Toni-Maree, Solomon, Benjamin, Pao, William, Carter, Scott L., Getz, Gad, Hayes, D. Neil, Wilkerson, Matthew D., Thunnissen, Erik, Travis, William D., Perner, Sven, Wright, Gavin ORCID: 0000-0002-7000-9305, Brambilla, Elisabeth, Buettner, Reinhard, Wolf, Juergen, Thomas, Roman, Gabler, Franziska, Wilkening, Ines, Mueller, Christian, Dahmen, Ilona, Menon, Roopika, Koenig, Katharina, Albus, Kerstin, Merkelbach-Bruse, Sabine, Fassunke, Jana, Schmitz, Katja, Kuenstlinger, Helen, Kleine, Michaela, Binot, Elke, Querings, Silvia, Altmueller, Janine, Boessmann, Ingelore, Nuemberg, Peter, Schneider, Peter, Bogus, Magdalena, Buettner, Reinhard, Perner, Sven, Russell, Prudence, Thunnissen, Erik, Travis, William D., Brambilla, Elisabeth, Soltermann, Alex, Moch, Holger, Brustugun, Odd Terje, Solberg, Steinar, Lund-Iversen, Marius, Helland, Aslaug ORCID: 0000-0002-5520-0275, Muley, Thomas, Hoffmann, Hans, Schnabel, Philipp A., Chen, Yuan, Groen, Harry, Timens, Wim ORCID: 0000-0002-4146-6363, Sietsma, Hannie, Clement, Joachim H. ORCID: 0000-0002-6601-2456, Weder, Walter, Saenger, Joerg, Stoelben, Erich, Ludwig, Corinna, Engel-Riedel, Walburga, Smit, Egbert, Heideman, Danille A. M., Snijders, Peter J. F., Nogova, Lucia, Sos, Martin L., Mattonet, Christian, Toepelt, Karin, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Goekkurt, Eray, Kappes, Rainer, Krueger, Stefan, Kambartel, Kato, Behringer, Dirk, Schulte, Wolfgang, Galetke, Wolfgang, Randerath, Winfried, Heldwein, Matthias, Schlesinger, Andreas, Serke, Monika, Hekmat, Khosro, Frank, Konrad F., Schnell, Roland, Reiser, Marcel, Huenerlituerkoglu, Ali-Nuri, Schmitz, Stephan, Meffert, Lisa, Ko, Yon-Dschun, Litt-Lampe, Markus, Gerigk, Ulrich, Fricke, Rainer, Besse, Benjamin ORCID: 0000-0001-5090-8189, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Moro-Sibilot, Denis, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John K. ORCID: 0000-0003-3951-6365, Hyde, Russell, Validire, Pierre, Girard, Philippe, Muscarella, Lucia A., Fazio, Vito M., Hallek, Michael, Soria, Jean-Charles, Carter, Scott L., Getz, Gad, Hayes, D. Neil, Wilkerson, Matthew D., Achter, Viktor, Lang, Ulrich ORCID: 0000-0001-7166-0805, Seidel, Danila ORCID: 0000-0003-4388-3117, Zander, Thomas, Heukamp, Lukas C., Peifer, Martin ORCID: 0000-0002-5243-5503, Bos, Marc, Pao, William, Travis, William D., Brambilla, Elisabeth, Buettner, Reinhard, Wolf, Juergen and Thomas, Roman K. (2013). A Genomics-Based Classification of Human Lung Tumors. Sci. Transl. Med., 5 (209). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Sos, Martin L., Dietlein, Felix, Peifer, Martin ORCID: 0000-0002-5243-5503, Schoettle, Jakob, Balke-Want, Hyatt, Mueller, Christian, Koker, Mirjam, Richters, Andre, Heynck, Stefanie, Malchers, Florian, Heuckmann, Johannes M., Seidel, Danila, Eyers, Patrick A., Ullrich, Roland T., Antonchick, Andrey P., Vintonyak, Viktor V., Schneider, Peter M. ORCID: 0000-0003-0744-2349, Ninomiya, Takashi, Waldmann, Herbert ORCID: 0000-0002-9606-7247, Buettner, Reinhard, Rauh, Daniel ORCID: 0000-0002-1970-7642, Heukamp, Lukas C. and Thomas, Roman K. (2012). A framework for identification of actionable cancer genome dependencies in small cell lung cancer. Proc. Natl. Acad. Sci. U. S. A., 109 (42). S. 17034 - 17040. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Tischler, Verena ORCID: 0000-0002-6673-8329, Pfeifer, Marco, Hausladen, Silke, Schirmer, Uwe, Bonde, Anne-Katrine, Kristiansen, Glen, Sos, Martin L., Weder, Walter, Moch, Holger, Altevogt, Peter and Soltermann, Alex (2011). L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer. Mol. Cancer, 10. LONDON: BIOMED CENTRAL LTD. ISSN 1476-4598

Tumbrink, Hannah L., Heimsoeth, Alena and Sos, Martin L. (2021). The next tier of EGFR resistance mutations in lung cancer. Oncogene, 40 (1). S. 1 - 12. LONDON: SPRINGERNATURE. ISSN 1476-5594

Weiss, Jonathan, Sos, Martin L., Seidel, Danila, Peifer, Martin ORCID: 0000-0002-5243-5503, Zander, Thomas, Heuckmann, Johannes M., Ullrich, Roland T., Menon, Roopika, Maier, Sebastian, Soltermann, Alex, Moch, Holger, Wagener, Patrick, Fischer, Florian, Heynck, Stefanie, Koker, Mirjam, Schoettle, Jakob, Leenders, Frauke, Gabler, Franziska, Dabow, Ines, Querings, Silvia, Heukamp, Lukas C., Balke-Want, Hyatt, Ansen, Sascha, Rauh, Daniel ORCID: 0000-0002-1970-7642, Baessmann, Ingelore, Altmueller, Janine, Wainer, Zoe, Conron, Matthew, Wright, Gavin ORCID: 0000-0002-7000-9305, Russell, Prudence, Solomon, Ben, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Sollberg, Steinar, Brustugun, Odd Terje, Engel-Riedel, Walburga, Ludwig, Corinna, Petersen, Iver, Saenger, Joerg, Clement, Joachim, Groen, Harry, Timens, Wim ORCID: 0000-0002-4146-6363, Sietsma, Hannie, Thunnissen, Erik ORCID: 0000-0001-5355-8508, Smit, Egbert, Heideman, Danielle, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Hallek, Michael, Beroukhim, Rameen, Pao, William, Klebl, Bert, Baumann, Matthias, Buettner, Reinhard, Ernestus, Karen, Stoelben, Erich, Wolf, Juergen, Nuernberg, Peter, Perner, Sven and Thomas, Roman K. (2010). Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer. Sci. Transl. Med., 2 (62). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Werr, Lisa ORCID: 0000-0002-3697-4136, Plenker, Dennis, Dammert, Marcel A., Lorenz, Carina, Bragelmann, Johannes, Tumbrink, Hannah L., Klein, Sebastian, Schmitt, Anna, Buttner, Reinhard, Persigehl, Thorsten, Shokat, Kevan M., Wunderlich, F. Thomas, Schram, Alison M., Peifer, Martin ORCID: 0000-0002-5243-5503, Sos, Martin L., Reinhardt, H. Christian and Thomas, Roman K. (2022). CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization. Mol. Cancer Ther., 21 (5). S. 821 - 831. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-8514