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2022
Hombach, Andreas ORCID: 0000-0001-9328-8442, Barden, Markus, Hannappel, Lisa, Chmielewski, Markus, Rappl, Gunter, Sachinidis, Agapios and Abken, Hinrich (2022). IL12 integrated into the CAR exodomain converts CD8(+) T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors. Mol. Ther., 30 (2). S. 593 - 606. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
Paasch, Daniela, Meyer, Johann, Stamopoulou, Andriana, Lenz, Daniela, Kuehle, Johannes, Kloos, Doreen, Buchegger, Theresa, Holzinger, Astrid, Falk, Christine S., Kloth, Christina, von Kaisenberg, Constantin S., Abken, Hinrich ORCID: 0000-0002-4302-3240, Schambach, Axel, Lachmann, Nico ORCID: 0000-0002-4245-1497, Morgan, Michael and Moritz, Thomas (2022). Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy. Cells, 11 (6). BASEL: MDPI. ISSN 2073-4409
2021
Ambrose, Christine, Su, Lihe, Wu, Lan, Dufort, Fay J., Sanford, Thomas, Birt, Alyssa, Hackel, Benjamin J., Hombach, Andreas ORCID: 0000-0001-9328-8442, Abken, Hinrich, Lobb, Roy R. and Rennert, Paul D. (2021). Anti-CD19 CAR T cells potently redirected to kill solid tumor cells. PLoS One, 16 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203
Bunse, Mario ORCID: 0000-0002-7554-2520, Pfeilschifter, Janina, Bluhm, Julia, Zschummel, Maria, Joedicke, Jara J., Wirges, Anthea, Stark, Helen ORCID: 0000-0002-5726-3958, Kretschmer, Vivien, Chmielewski, Markus, Uckert, Wolfgang, Abken, Hinrich, Westermann, Joerg, Rehm, Armin ORCID: 0000-0001-7490-1950 and Hoepken, Uta E. (2021). CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells. Nat. Commun., 12 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723
Rudek, Loreen Sophie, Zimmermann, Katharina, Galla, Melanie, Meyer, Johann, Kuehle, Johannes, Stamopoulou, Andriana, Brand, Daniel, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Rossig, Claudia, Altvater, Bianca, Falk, Christine S., Abken, Hinrich, Morgan, Michael Alexander and Schambach, Axel (2021). Generation of an NF kappa B-Driven Alpharetroviral All-in-One Vector Construct as a Potent Tool for CAR NK Cell Therapy. Front. Immunol., 12. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-3224
2020
Alzubi, Jamal, Dettmer-Monaco, Viviane, Kuehle, Johannes, Thorausch, Niko, Seidl, Maximilian, Taromi, Sanaz, Schamel, Wolfgang, Zeiser, Robert, Abken, Hinrich, Cathomen, Toni ORCID: 0000-0002-7757-4630 and Wolf, Philipp (2020). PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model. Mol. Ther.-Oncolytics, 18. S. 226 - 236. CAMBRIDGE: CELL PRESS. ISSN 2372-7705
Hombach, Andreas A., Geumann, Ulf, Guenther, Christine, Hermann, Felix G. and Abken, Hinrich (2020). IL7-IL12 Engineered Mesenchymal Stem Cells (MSCs) Improve A CAR T Cell Attack Against Colorectal Cancer Cells. Cells, 9 (4). BASEL: MDPI. ISSN 2073-4409
Nemade, Harshal, Acharya, Aviseka, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Nembo, Erastus, Nguemo, Filomain ORCID: 0000-0002-2236-6797, Riet, Nicole, Abken, Hinrich, Hescheler, Juergen, Papadopoulos, Symeon and Sachinidis, Agapios (2020). Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Cells, 9 (3). BASEL: MDPI. ISSN 2073-4409
Nemade, Harshal, Acharya, Aviseka, Chaudhari, Umesh, Nembo, Erastus, Nguemo, Filomain, Riet, Nicole, Abken, Hinrich, Hescheler, Jurgen, Papadopoulos, Symeon and Sachinidis, Agapios (2020). Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells (vol 9, 554, 2020). Cells, 9 (10). BASEL: MDPI. ISSN 2073-4409
Patasic, Lea, Seifried, Janna, Bezler, Valerie, Kaljanac, Marcell, Schneider, Irene C., Schmitz, Heike, Tondera, Christiane, Hartmann, Jessica, Hombach, Andreas, Buchholz, Christian J., Abken, Hinrich, Koenig, Renate and Cichutek, Klaus (2020). Designed Ankyrin Repeat Protein (DARPin) to target chimeric antigen receptor (CAR)-redirected T cells towards CD4(+)T cells to reduce the latent HIV(+)cell reservoir. Med. Microbiol. Immunol., 209 (6). S. 681 - 692. NEW YORK: SPRINGER. ISSN 1432-1831
Zimmermann, Katharina, Kuehle, Johannes, Dragon, Anna Christina ORCID: 0000-0002-5228-7627, Galla, Melanie, Kloth, Christina, Rudek, Loreen Sophie, Sandalcioglu, I. Erol, Neyazi, Belal, Moritz, Thomas, Meyer, Johann, Rossig, Claudia, Altvater, Bianca, Eiz-Vesper, Britta, Morgan, Michael Alexander, Abken, Hinrich and Schambach, Axel (2020). Design and Characterization of an All-in-One Lentiviral Vector System Combining Constitutive Anti-G(D2) CAR Expression and Inducible Cytokines. Cancers, 12 (2). BASEL: MDPI. ISSN 2072-6694
2019
Aleksandrova, Krasimira, Leise, Jana, Priesner, Christoph, Melk, Anette, Kubaink, Fanni, Abken, Hinrich, Hombach, Andreas, Aktas, Murat, Essl, Mike, Buerger, Iris, Kaiser, Andrew, Rauser, Georg, Jurk, Marion, Goudeva, Lilia, Glienke, Wolfgang, Arseniev, Lubomir, Esser, Ruth and Koehl, Ulrike (2019). Functionality and Cell Senescence of CD4/CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy (R) Platform. Transfus. Med. Hemother., 46 (1). S. 47 - 55. BASEL: KARGER. ISSN 1660-3818
Chmielewski, Markus, Kuehle, Johannes, Chrobok, Danuta, Riet, Nicole, Hallek, Michael and Abken, Hinrich (2019). FimH-based display of functional eukaryotic proteins on bacteria surfaces. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322
Hombach, Andreas A., Rappl, Gunter and Abken, Hinrich (2019). Blocking CD30 on T Cells by a Dual Specific CAR for CD30 and Colon Cancer Antigens Improves the CAR T Cell Response against CD30(-) Tumors. Mol. Ther., 27 (10). S. 1825 - 1836. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
2018
Bergmeier, Vera, Etich, Julia ORCID: 0000-0003-3238-6692, Pitzler, Lena, Frie, Christian, Koch, Manuel, Fischer, Matthias, Rappl, Gunter, Abken, Hinrich, Tomasek, James J. and Brachvogel, Bent (2018). Identification of a myofibroblast-specific expression signature in skin wounds. Matrix Biol., 65. S. 59 - 75. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1569-1802
Bluhm, Julia, Kieback, Elisa, Marino, Stephen F., Oden, Felix, Westermann, Joerg, Chmielewski, Markus, Abken, Hinrich, Uckert, Wolfgang, Hoepken, Uta E. and Rehm, Armin (2018). CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma. Mol. Ther., 26 (8). S. 1906 - 1921. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
De Munter, Stijn ORCID: 0000-0003-3821-0620, Ingels, Joline, Goetgeluk, Glenn, Bonte, Sarah, Pille, Melissa ORCID: 0000-0002-2757-6486, Weening, Karin, Kerre, Tessa, Abken, Hinrich and Vandekerckhove, Bart ORCID: 0000-0003-3828-4195 (2018). Nanobody Based Dual Specific CARs. Int. J. Mol. Sci., 19 (2). BASEL: MDPI. ISSN 1422-0067
Golumba-Nagy, Viktoria, Kuehle, Johannes, Hombach, Andreas A. and Abken, Hinrich (2018). CD28-zeta CAR T Cells Resist TGF-beta Repression through IL-2 Signaling, Which Can Be Mimicked by an Engineered IL-7 Autocrine Loop. Mol. Ther., 26 (9). S. 2218 - 2231. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
Koehl, Ulrike, Arsenieva, Stanislava, Holzinger, Astrid and Abken, Hinrich (2018). CAR T Cells in Trials: Recent Achievements and Challenges that Remain in the Production of Modified T Cells for Clinical Applications. Hum. Gene Ther., 29 (5). S. 559 - 569. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422
Probst, Kristina, Stermann, Jacek, von Bomhard, Inga, Etich, Julia ORCID: 0000-0003-3238-6692, Pitzler, Lena, Niehoff, Anja, Bluhm, Bjoern, Xu, Haifeng C., Lang, Philipp A., Chmielewski, Markus, Abken, Hinrich, Blissenbach, Birgit, Machova, Alzbeta, Papadopoulou, Nikoletta and Brachvogel, Bent (2018). Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function. Stem Cells, 36 (11). S. 1752 - 1764. HOBOKEN: WILEY. ISSN 1549-4918
Schirmer, David, Storz, Isabel, Wisskirchen, Karin, Feederle, Regina, Schmidt, Oxana, Abken, Hinrich, Protzer, Ulrike, Burdach, Stefan and Richter, Guenther H. S. (2018). GPR64-specific CAR-transgenic T cells selectively kill Ewing sarcoma in vivo. Cancer Res., 78 (19). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445
Szoor, Arpad, Szollosi, Janos, Abken, Hinrich and Vereb, Gyorgy (2018). Surface Mobility and Cluster Formation of Various Melanoma Associated Antigens Modulates Car T Cell Activation. Mol. Ther., 26 (5). S. 35 - 36. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
2017
Abken, Hinrich (2017). Driving CARs on the Highway to Solid Cancer: Some Considerations on the Adoptive Therapy with CAR T Cells. Hum. Gene Ther., 28 (11). S. 1047 - 1061. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422
Chmielewski, Markus and Abken, Hinrich (2017). CAR T Cells Releasing IL-18 Convert to T-Bet(high) FoxO1(low) Effectors that Exhibit Augmented Activity against Advanced Solid Tumors. Cell Reports, 21 (11). S. 3205 - 3220. CAMBRIDGE: CELL PRESS. ISSN 2211-1247
Golumba-Nagy, Viktoria, Kuehle, Johannes and Abken, Hinrich (2017). Genetic Modification of T Cells with Chimeric Antigen Receptors: A Laboratory Manual. Hum. Gene Ther. Methods, 28 (6). S. 302 - 310. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1946-6544
Herling, Marco, Rengstl, Benjamin, Scholtysik, Rene, Hartmann, Sylvia, Kueppers, Ralf, Hansmann, Martin-Leo, Diebner, Hans H. ORCID: 0000-0002-7138-6372, Roeder, Ingo, Abken, Hinrich, Newrzela, Sebastian and Kirberg, Joerg (2017). Concepts in mature T-cell lymphomas - highlights from an international joint symposium on T-cell immunology and oncology. Leuk. Lymphoma, 58 (4). S. 788 - 797. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1029-2403
Holzinger, Astrid and Abken, Hinrich (2017). CAR T cells targeting solid tumors: carcinoembryonic antigen (CEA) proves to be a safe target. Cancer Immunol. Immunother., 66 (11). S. 1505 - 1508. NEW YORK: SPRINGER. ISSN 1432-0851
Hombach, Andreas A. and Abken, Hinrich (2017). Most Do, but Some Do Not: CD4(+)CD25(-) T Cells, but Not CD4(+)CD25(+) Treg Cells, Are Cytolytic When Redirected by a Chimeric Antigen Receptor (CAR). Cancers, 9 (9). BASEL: MDPI. ISSN 2072-6694
Hombach, Andreas A. and Abken, Hinrich (2017). Shared target antigens on cancer cells and tissue stem cells: go or no-go for CAR T cells? Expert Rev. Clin. Immunol., 13 (2). S. 151 - 156. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-8409
Martyniszyn, Alexandra, Krahl, Ann-Christin, Andre, Maya C., Hombach, Andreas A. and Abken, Hinrich (2017). CD20-CD19 Bispecific CAR T Cells for the Treatment of B-Cell Malignancies. Hum. Gene Ther., 28 (12). S. 1147 - 1158. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422
Sabour, Davood, Srinivasan, Sureshkumar Perumal, Rohani, Susan, Wagh, Vilas, Gaspar, John Antonydas, Panek, Darius, Ardestani, Mostafa Abootorabi, Doss, Michael Xavier, Riet, Nicole, Abken, Hinrich, Hescheler, Juergen, Papadopoulos, Symeon and Sachinidis, Agapios (2017). STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation. Mol.Ther.-Methods Clin. Dev., 5. S. 116 - 130. CAMBRIDGE: CELL PRESS. ISSN 2329-0501
Shimabukuro-Vornhagen, Alexander ORCID: 0000-0002-2351-7294, Garcia-Marquez, Maria Alejandra ORCID: 0000-0002-5923-5942, Fischer, Rieke N., Iltgen-Breburda, Juliane, Fiedler, Anne, Wennhold, Kerstin ORCID: 0000-0001-5539-7226, Rappl, Gunter ORCID: 0000-0003-0402-7940, Abken, Hinrich ORCID: 0000-0002-4302-3240, Lehmann, Clara ORCID: 0000-0002-7042-1578, Herling, Marco, Wolf, Dominik, Fätkenheuer, Gerd ORCID: 0000-0002-5054-1871, Rubbert-Roth, Andrea ORCID: 0000-0002-9016-2833, Hallek, Michael ORCID: 0000-0002-7425-4455, Theurich, Sebastian ORCID: 0000-0001-5706-8258 and von Bergwelt-Baildon, Michael (2017). Antigen-presenting human B cells are expanded in inflammatory conditions. J. Leukoc. Biol., 101 (2). S. 577 - 588. HOBOKEN: WILEY. ISSN 1938-3673
Skuljec, Jelena ORCID: 0000-0001-8509-6563, Chmielewski, Markus, Happle, Christine, Habener, Anika, Busse, Mandy, Abken, Hinrich and Hansen, Gesine (2017). Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma. Front. Immunol., 8. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-3224
Storz, Isabel, Schirmer, David, Wisskirchen, Karin, Feederle, Regina, Schmidt, Oxana, Abken, Hinrich, Protzer, Ulrike, Burdach, Stefan and Richter, Guenther H. S. (2017). Therapeutic potential of GPR64 specific CAR T cells in pediatric sarcomas. Cancer Immunol. Res., 5 (3). PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2326-6074
Van Caeneghem, Yasmine, De Munter, Stijn ORCID: 0000-0003-3821-0620, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges ORCID: 0000-0002-1691-5294, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich and Vandekerckhove, Bart ORCID: 0000-0003-3828-4195 (2017). Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities. OncoImmunology, 6 (3). PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X
Wennhold, Kerstin ORCID: 0000-0001-5539-7226, Thelen, Martin ORCID: 0000-0002-2785-9726, Schloesser, Hans Anton, Haustein, Natalie, Reuter, Sabrina, Garcia-Marquez, Maria, Lechner, Axel, Kobold, Sebastian, Rataj, Felicitas, Utermoehlen, Olaf, Chakupurakal, Geothy, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Hallek, Michael, Abken, Hinrich, Shimabukuro-Vornhagen, Alexander and von Bergwelt-Baildon, Michael (2017). Using Antigen-Specific B Cells to Combine Antibody and T Cell-Based Cancer Immunotherapy. Cancer Immunol. Res., 5 (9). S. 730 - 744. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2326-6074
2016
Abken, Hinrich (2016). Costimulation Engages the Gear in Driving CARs. Immunity, 44 (2). S. 214 - 217. CAMBRIDGE: CELL PRESS. ISSN 1097-4180
Borgal, Lori, Rinschen, Markus M., Dafinger, Claudia, Liebrecht, Valerie I., Abken, Hinrich, Benzing, Thomas and Schermer, Bernhard ORCID: 0000-0002-5194-9000 (2016). Jade-1S phosphorylation induced by CK1 alpha contributes to cell cycle progression. Cell Cycle, 15 (8). S. 1034 - 1046. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1551-4005
Chmielewski, Markus and Abken, Hinrich (2016). Release brakes: chimeric antigen receptor T cells with PD-1 switch receptor. Transl. Cancer Res., 5 (3). S. 229 - 233. SHATIN: AME PUBL CO. ISSN 2219-6803
Faitschuk, Elena, Hombach, Andreas A., Frenzel, Lukas P., Wendtner, Clemens-Martin and Abken, Hinrich (2016). Chimeric antigen receptor T cells targeting Fc mu receptor selectively eliminate CLL cells while sparing healthy B cells. Blood, 128 (13). S. 1711 - 1723. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020
Holzinger, Astrid, Barden, Markus and Abken, Hinrich (2016). The growing world of CAR T cell trials: a systematic review. Cancer Immunol. Immunother., 65 (12). S. 1433 - 1451. NEW YORK: SPRINGER. ISSN 1432-0851
Hombach, Andreas A., Goergens, Andre, Chmielewski, Markus, Murke, Florian, Kimpel, Janine ORCID: 0000-0002-5210-7905, Giebel, Bernd ORCID: 0000-0003-2446-948X and Abken, Hinrich (2016). Superior Therapeutic Index in Lymphoma Therapy: CD30(+) CD34(+) Hematopoietic Stem Cells Resist a Chimeric Antigen Receptor T-cell Attack. Mol. Ther., 24 (8). S. 1423 - 1435. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
Ligtenberg, Maarten A., Mougiakakos, Dimitrios, Mukhopadhyay, Madhura, Witt, Kristina, Lladser, Alvaro, Chmielewski, Markus, Riet, Tobias, Abken, Hinrich and Kiessling, Rolf (2016). Coexpressed Catalase Protects Chimeric Antigen Receptor-Redirected T Cells as well as Bystander Cells from Oxidative Stress-Induced Loss of Antitumor Activity. J. Immunol., 196 (2). S. 759 - 767. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606
Rengstl, Benjamin, Schmid, Frederike, Weiser, Christian, Doering, Claudia, Heinrich, Tim, Warner, Kathrin, Becker, Petra S. A., Wistinghausen, Robin, Kameh-Var, Sima, Werling, Eva, Billmeier, Arne, Seidl, Christian, Hartmann, Sylvia, Abken, Hinrich, Kueppers, Ralf, Hansmann, Martin-Leo and Newrzela, Sebastian (2016). Tumor-infiltrating HLA-matched CD4(+) T cells retargeted against Hodgkin and Reed-Sternberg cells. OncoImmunology, 5 (6). PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X
2015
Abken, Hinrich (2015). Adoptive therapy with CAR redirected T cells: the challenges in targeting solid tumors. Immunotherapy, 7 (5). S. 535 - 545. LONDON: FUTURE MEDICINE LTD. ISSN 1750-7448
Chmielewski, Markus and Abken, Hinrich (2015). TRUCKs: the fourth generation of CARs. Expert Opin. Biol. Ther., 15 (8). S. 1145 - 1155. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-7682
Friedel, Thorsten, Hanisch, Lydia J., Muth, Anke, Honegger, Annemarie ORCID: 0000-0002-3378-3967, Abken, Hinrich, Plueckthun, Andreas, Buchholz, Christian J. and Schneider, Irene C. (2015). Receptor-targeted lentiviral vectors are exceptionally sensitive toward the biophysical properties of the displayed single-chain Fv. Protein Eng. Des. Sel., 28 (4). S. 93 - 106. OXFORD: OXFORD UNIV PRESS. ISSN 1741-0134
Friedel, Thorsten, Hanisch, Lydia J., Muth, Anke, Honegger, Annemarie ORCID: 0000-0002-3378-3967, Abken, Hinrich, Plueckthun, Andreas, Buchholz, Christian J. and Schneider, Irene C. (2015). Receptor-targeted lentiviral vectors are exceptionally sensitive toward the biophysical properties of the displayed single-chain Fv. Protein Eng. Des. Sel., 28 (4). S. 93 - 106. OXFORD: OXFORD UNIV PRESS. ISSN 1741-0134
Jakobshagen, Kristin, Ward, Beate, Baschuk, Nikola, Huss, Sebastian, Brunn, Anna, Malecki, Monika, Fiolka, Michael, Rappl, Gunther, Corogeanu, Diana, Karow, Ulrike, Schiller, Petra, Abken, Hinrich, Heukamp, Lukas C., Deckert, Martina, Kroenke, Martin and Utermoehlen, Olaf (2015). Endogenous Il10 Alleviates the Systemic Antiviral Cellular Immune Response and T Cell-Mediated Immunopathology in Select Organs of Acutely LCMV-Infected Mice. Am. J. Pathol., 185 (11). S. 3025 - 3039. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1525-2191
Kobold, Sebastian, Steffen, Julius, Chaloupka, Michael, Grassmann, Simon, Henkel, Jonas, Castoldi, Raffaella, Zeng, Yi, Chmielewski, Markus, Schmollinger, Jan C., Schnurr, Max, Rothenfusser, Simon, Schendel, Dolores J., Abken, Hinrich, Sustmann, Claudio, Niederfellner, Gerhard, Klein, Christian ORCID: 0000-0001-7594-7280, Bourquin, Carole ORCID: 0000-0003-3862-4583 and Endres, Stefan (2015). Selective Bispecific T Cell Recruiting Antibody and Antitumor Activity of Adoptive T Cell Transfer. JNCI-J. Natl. Cancer Inst., 107 (1). CARY: OXFORD UNIV PRESS INC. ISSN 1460-2105
Krug, Christian, Birkholz, Katrin, Paulus, Alexander, Schwenkert, Michael, Schmidt, Patrick ORCID: 0000-0002-1917-1446, Hoffmann, Nicole, Hombach, Andreas, Fey, Georg, Abken, Hinrich, Schuler, Gerold, Schuler-Thurner, Beatrice, Doerrie, Jan and Schaft, Niels ORCID: 0000-0001-8236-9298 (2015). Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone. Cancer Immunol. Immunother., 64 (12). S. 1623 - 1636. NEW YORK: SPRINGER. ISSN 1432-0851
Riet, Tobias and Abken, Hinrich (2015). Chimeric antigen receptor T cells: power tools to wipe out leukemia and lymphoma. Expert Rev. Hematol., 8 (4). S. 383 - 386. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1747-4094
Schmied, Sabine, Gostick, Emma, Price, David A., Abken, Hinrich, Assenmacher, Mario and Richter, Anne (2015). Analysis of the functional WT1-specific T-cell repertoire in healthy donors reveals a discrepancy between CD4(+) and CD8(+) memory formation. Immunology, 145 (4). S. 558 - 570. HOBOKEN: WILEY. ISSN 1365-2567
Shimabukuro-Vornhagen, Alexander, Marquez, Maria Alejandra Garcia, Fischer, Rieke N., Iltgen-Breburda, Juliane, Fiedler, Anne, Wennhold, Kerstin, Rappl, Gunter, Abken, Hinrich, Hartmann, Pia, Lehmann, Clara, Koslowsky, Thomas, Herling, Marco, Beutner, Dirk, Wolf, Dominik, Faetkenheuer, Gerd, Rubbert-Roth, Andrea, Hallek, Michael, Theurich, Sebastian and von Bergwelt-Baildon, Michael (2015). Human CD21(low) CD86(pos) B Cells Are Potent Antigen Presenting Cells, Which Are Expanded in Inflammatory Conditions. Blood, 126 (23). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020
Stauss, Hans J., Morris, Emma C. and Abken, Hinrich (2015). Cancer gene therapy with T cell receptors and chimeric antigen receptors. Curr. Opin. Pharmacol., 24. S. 113 - 119. OXFORD: ELSEVIER SCI LTD. ISSN 1471-4973
van Caeneghem, Yasmine, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges ORCID: 0000-0002-1691-5294, Offner, Fritz, Abken, Hinrich, Kerre, Tessa and Vandekerkhove, Bart (2015). Chimeric Antigen Receptor Transgenic, T Cell Receptor/CD3 Negative Monospecific T Cells Generated from Cord Blood CD34 Positive Cells. Blood, 126 (23). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020
2014
Abken, Hinrich (2014). TRUCKs: the new generation of CARs. Hum. Gene Ther., 25 (11). S. A12 - 2. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-7422
Brinkmann, Kerstin, Hombach, Andreas, Seeger, Jens Michael, Wagner-Stippich, Diana, Klubertz, Daniela, Kroenke, Martin, Abken, Hinrich and Kashkar, Hamid (2014). Second mitochondria-derived activator of caspase (SMAC) mimetic potentiates tumor susceptibility toward natural killer cell-mediated killing. Leuk. Lymphoma, 55 (3). S. 645 - 652. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1029-2403
Chmielewski, Markus, Hombach, Andreas A. and Abken, Hinrich (2014). Of CARs and TRUCKs: chimeric antigen receptor (CAR) T cells engineered with an inducible cytokine to modulate the tumor stroma. Immunol. Rev., 257 (1). S. 83 - 91. HOBOKEN: WILEY. ISSN 1600-065X
Krug, Christian, Wiesinger, Manuel, Abken, Hinrich, Schuler-Thurner, Beatrice, Schuler, Gerold, Dorrie, Jan ORCID: 0000-0002-3478-0741 and Schaft, Niels ORCID: 0000-0001-8236-9298 (2014). A GMP-compliant protocol to expand and transfect cancer patient T cells with mRNA encoding a tumor-specific chimeric antigen receptor. Cancer Immunol. Immunother., 63 (10). S. 999 - 1009. NEW YORK: SPRINGER. ISSN 1432-0851
Textor, Ana, Listopad, Joanna J., Le Wuehrmann, Lara, Perez, Cynthia ORCID: 0000-0002-2260-5428, Kruschinski, Anna, Chmielewski, Markus, Abken, Hinrich, Blankenstein, Thomas and Charo, Jehad (2014). Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFN gamma. Cancer Res., 74 (23). S. 6796 - 6806. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445
2013
Hombach, Andreas A., Rappl, Gunter and Abken, Hinrich (2013). Arming Cytokine-induced Killer Cells With Chimeric Antigen Receptors: CD28 Outperforms Combined CD28 OX40 Super-stimulation. Mol. Ther., 21 (12). S. 2268 - 2278. CAMBRIDGE: CELL PRESS. ISSN 1525-0024
2012
Chmielewski, Markus, Hahn, Olga, Rappl, Gunter, Nowak, Michael, Schmidt-Wolf, Ingo H., Hombach, Andreas A. and Abken, Hinrich (2012). T Cells That Target Carcinoembryonic Antigen Eradicate Orthotopic Pancreatic Carcinomas Without Inducing Autoimmune Colitis in Mice. Gastroenterology, 143 (4). S. 1095 - 1110. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 0016-5085
Chmielewski, Markus, Maliar, Amit, Eshhar, Zelig and Abken, Hinrich (2012). CAR's made it to the pancreas. OncoImmunology, 1 (8). S. 1387 - 1390. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X
Grskovic, Ivan, Kutsch, Anna, Frie, Christian, Groma, Gergely, Stermann, Jacek, Schloetzer-Schrehardt, Ursula, Niehoff, Anja ORCID: 0000-0002-4165-0929, Moss, Stephen E., Rosenbaum, Sabrina, Poeschl, Ernst, Chmielewski, Markus, Rappl, Gunter, Abken, Hinrich, Bateman, John F., Cheah, Kathryn S. E., Paulsson, Mats and Brachvogel, Bent (2012). Depletion of Annexin A5, Annexin A6, and Collagen X Causes No Gross Changes in Matrix Vesicle-Mediated Mineralization, but Lack of Collagen X Affects Hematopoiesis and the Th1/Th2 Response. J. Bone Miner. Res., 27 (11). S. 2399 - 2413. HOBOKEN: WILEY-BLACKWELL. ISSN 0884-0431
Jahn, Tobias, Zuther, Martin, Friedrichs, Bjoern, Heuser, Claudia, Guhlke, Stefan, Abken, Hinrich and Hombach, Andreas A. (2012). An IL12-IL2-Antibody Fusion Protein Targeting Hodgkin's Lymphoma Cells Potentiates Activation of NK and T cells for an Anti-Tumor Attack. PLoS One, 7 (9). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203
Maliar, Amit, Servais, Charlotte, Waks, Tova, Chmielewski, Markus, Lavy, Ron, Altevogt, Peter, Abken, Hinrich and Eshhar, Zelig (2012). Redirected T Cells That Target Pancreatic Adenocarcinoma Antigens Eliminate Tumors and Metastases in Mice. Gastroenterology, 143 (5). S. 1375 - 1390. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. ISSN 1528-0012
2011
Chmielewski, Markus, Kopecky, Caroline, Hombach, Andreas A. and Abken, Hinrich (2011). IL-12 Release by Engineered T Cells Expressing Chimeric Antigen Receptors Can Effectively Muster an Antigen-Independent Macrophage Response on Tumor Cells That Have Shut Down Tumor Antigen Expression. Cancer Res., 71 (17). S. 5697 - 5707. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 0008-5472
Hombach, Andreas A. and Abken, Hinrich (2011). Costimulation by chimeric antigen receptors revisited: the T cell antitumor response benefits from combined CD28-OX40 signalling. Int. J. Cancer, 129 (12). S. 2935 - 2945. HOBOKEN: WILEY. ISSN 1097-0215