Universität zu Köln

Journal Article

Ackermann, Leena ORCID: 0000-0001-6405-900X, Schell, Michael, Pokrzywa, Wojciech ORCID: 0000-0002-5110-4462, Kevei, Eva ORCID: 0000-0002-0560-9208, Gartner, Anton ORCID: 0000-0003-4639-9902, Schumacher, Bjoern and Hoppe, Thorsten ORCID: 0000-0002-4734-9352 (2016). E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis. Nat. Struct. Mol. Biol., 23 (11). S. 995 - 1003. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1545-9985

Babu, Vipin ORCID: 0000-0002-0001-8783, Hofmann, Kay ORCID: 0000-0002-2289-9083 and Schumacher, Bjoern (2014). A C. elegans homolog of the Cockayne syndrome complementation group A gene. DNA Repair, 24. S. 57 - 63. AMSTERDAM: ELSEVIER. ISSN 1568-7856

Babu, Vipin ORCID: 0000-0002-0001-8783 and Schumacher, Bjoern (2016). A C. elegans homolog for the UV-hypersensitivity syndrome disease gene UVSSA. DNA Repair, 41. S. 8 - 16. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1568-7856

Barzilai, Ari, Schumacher, Bjoern and Shiloh, Yosef (2017). Genome instability: Linking ageing and brain degeneration. Mech. Ageing Dev., 161. S. 4 - 19. CLARE: ELSEVIER IRELAND LTD. ISSN 0047-6374

Behrens, Axel ORCID: 0000-0002-1557-1143, van Deursen, Jan M., Rudolph, K. Lenhard and Schumacher, Bjoern (2014). Impact of genomic damage and ageing on stem cell function. Nat. Cell Biol., 16 (3). S. 201 - 208. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4679

Bianco, Julien N. and Schumacher, Bjoern (2018). MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO. Nucleic Acids Res., 46 (12). S. 6129 - 6140. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Bujarrabal, Arturo and Schumacher, Bjoern (2017). Tracking senescent cells: A new biomarker assay opens new avenues in senescence research. Mech. Ageing Dev., 162. S. 106 - 108. CLARE: ELSEVIER IRELAND LTD. ISSN 0047-6374

Castells-Roca, Laia ORCID: 0000-0002-4604-9999, Mueller, Michael M. and Schumacher, Bjoern (2015). Longevity through DNA damage tolerance. Cell Cycle, 14 (4). S. 467 - 469. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1551-4005

Castells-Roca, Laia ORCID: 0000-0002-4604-9999, Mueller, Michael M. and Schumacher, Bjoern (2015). Longevity through DNA damage tolerance. Cell Cycle, 14 (4). S. 467 - 469. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1551-4005

Chatzidoukaki, Ourania, Goulielmaki, Evi, Schumacher, Bjoern and Garinis, George A. ORCID: 0000-0002-3200-5004 (2020). DNA Damage Response and Metabolic Reprogramming in Health and Disease. Trends Genet., 36 (10). S. 777 - 792. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1362-4555

Doll, Markus Alexander, Soltanmohammadi, Najmeh and Schumacher, Bjoern (2019). ALG-2/AGO-Dependent mir-35 Family Regulates DNA Damage-Induced Apoptosis Through MPK-1/ERK MAPK Signaling Downstream of the Core Apoptotic Machinery in Caenorhabditis elegans. Genetics, 213 (1). S. 173 - 195. BETHESDA: GENETICS SOCIETY AMERICA. ISSN 1943-2631

Edifizi, Diletta, Nolte, Hendrik, Babu, Vipin ORCID: 0000-0002-0001-8783, Castells-Roca, Laia ORCID: 0000-0002-4604-9999, Mueller, Michael M., Brodesser, Susanne, Krueger, Marcus ORCID: 0000-0003-2008-4582 and Schumacher, Bjoern (2017). Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans. Cell Reports, 20 (9). S. 2026 - 2044. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Edifizi, Diletta and Schumacher, Bjoern (2015). Genome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and Worms. Biomolecules, 5 (3). S. 1855 - 1870. BASEL: MDPI. ISSN 2218-273X

Edifizi, Diletta and Schumacher, Bjoern (2017). Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging. Int. J. Mol. Sci., 18 (11). BASEL: MDPI. ISSN 1422-0067

Ermolaeva, Maria A., Dakhovnik, Alexander and Schumacher, Bjoern (2015). Quality control mechanisms in cellular and systemic DNA damage responses. Ageing Res. Rev., 23. S. 3 - 12. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-9649

Ermolaeva, Maria A. and Schumacher, Bjoern (2014). Insights from the worm: The C. elegans model for innate immunity. Semin. Immunol., 26 (4). S. 303 - 310. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. ISSN 1096-3618

Ermolaeva, Maria A. and Schumacher, Bjoern (2014). Systemic DNA damage responses: organismal adapatations to genome instability. Trends Genet., 30 (3). S. 95 - 103. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1362-4555

Ermolaeva, Maria A., Segref, Alexandra ORCID: 0000-0001-8095-4469, Dakhovnik, Alexander, Ou, Hui-Ling, Schneider, Jennifer I., Utermoehlen, Olaf, Hoppe, Thorsten ORCID: 0000-0002-4734-9352 and Schumacher, Bjoern (2013). DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance. Nature, 501 (7467). S. 416 - 422. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Fernandez-Majada, Vanesa, Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, Ermolaeva, Maria A., Schell, Michael, Adam, Alexander, Dietlein, Felix, Komander, David, Buettner, Reinhard, Thomas, Roman K., Schumacher, Bjoern and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). The tumour suppressor CYLD regulates the p53 DNA damage response. Nat. Commun., 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Garinis, George A., Schwer, Bjoern and Schumacher, Bjoern (2017). Editorial: DNA damage & immunity. Mech. Ageing Dev., 165. S. 1 - 3. CLARE: ELSEVIER IRELAND LTD. ISSN 0047-6374

Gazzi, Arianna ORCID: 0000-0002-4142-485X, Fusco, Laura ORCID: 0000-0003-1418-507X, Orecchioni, Marco, Ferrari, Silvia, Franzoni, Giulia ORCID: 0000-0003-0987-3863, Yan, J. Stephen, Rieckher, Matthias, Peng, Guotao, Lucherelli, Matteo Andrea ORCID: 0000-0003-1055-3269, Anna Vacchi, Isabella, Criado, Alejandro ORCID: 0000-0002-9732-513X, Istif, Akcan, Mancino, Donato, Dominguez, Antonio, Eckert, Hagen ORCID: 0000-0003-4771-1435, Vazquez, Ester, Da Ros, Tatiana, Nicolussi, Paola, Palermo, Vincenzo, Schumacher, Bjoern, Cuniberti, Gianaurelio, Mai, Yiyong, Clementi, Cecilia, Pasquali, Matteo, Feng, Xinliang, Kostarelos, Kostas, Yilmazer, Acelya, Bedognetti, Davide, Fadeel, Bengt, Prato, Maurizio, Bianco, Alberto and Delogu, Lucia Gemma ORCID: 0000-0002-2329-7260 (2020). Graphene, other carbon nanomaterials and the immune system: toward nanoimmunity-by-design. J. Phys-Mater., 3 (3). BRISTOL: IOP PUBLISHING LTD. ISSN 2515-7639

Gebel, Jakob, Tuppi, Marcel ORCID: 0000-0002-2963-5902, Saenger, Nicole, Schumacher, Bjoern and Doetsch, Volker (2020). DNA Damaged Induced Cell Death in Oocytes. Molecules, 25 (23). BASEL: MDPI. ISSN 1420-3049

Habermehl, Tracy L., Parkinson, Kate C., Hubbard, Gene B., Ikeno, Yuji, Engelmeyer, Jennifer I., Schumacher, Bjoern and Mason, Jeffrey B. (2019). Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice. GeroScience, 41 (1). S. 25 - 39. DORDRECHT: SPRINGER. ISSN 2509-2723

Hoepker, Katja, Hagmann, Henning, Khurshid, Safiya, Chen, Shuhua, Hasskamp, Pia, Seeger-Nukpezah, Tamina, Schilberg, Katharina, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Lamkemeyer, Tobias, Sos, Martin L., Thomas, Roman K., Lowery, Drew, Roels, Frederik, Fischer, Matthias, Liebau, Max C., Resch, Ulrike ORCID: 0000-0002-8380-9555, Kisner, Tuelay, Roether, Fabian, Bartram, Malte P., Mueller, Roman Ulrich, Fabretti, Francesca, Kurschat, Peter, Schumacher, Bjoern, Gaestel, Matthias ORCID: 0000-0002-4944-4652, Medema, Rene H., Yaffe, Michael B., Schermer, Bernhard ORCID: 0000-0002-5194-9000, Reinhardt, H. Christian and Benzing, Thomas (2012). AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis. Embo J., 31 (20). S. 3961 - 3976. HOBOKEN: WILEY. ISSN 1460-2075

Jokic, Mladen, Vlasic, Ignacija, Rinneburger, Miriam ORCID: 0000-0003-3980-931X, Kluemper, Niklas, Spiro, Judith, Vogel, Wenzel, Offermann, Anne, Kuempers, Christiane, Fritz, Christian, Schmitt, Anna, Riabinska, Arina, Wittersheim, Maike, Michels, Sebastian, Ozretic, Luka, Florin, Alexandra, Welcker, Daniela, Akyuz, Mehmet Deniz, Nowak, Michael, Erkel, Martin, Wolf, Juergen, Buettner, Reinhard, Schumacher, Bjoern, Thomale, Juergen, Persigehl, Thorsten, Maintz, David, Perner, Sven and Reinhardt, Hans Christian (2016). Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner. Mol. Cancer Res., 14 (11). S. 1110 - 1124. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3125

Lohmann, Gregor, Schumacher, Bjoern and Herling, Marco (2017). Nucleotide excision repair as a targetable vulnerability in leukemia. Oncotarget, 8 (70). S. 114420 - 114422. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Meyer, David H. ORCID: 0000-0002-5667-4720 and Schumacher, Bjoern (2021). BiT age: A transcriptome-based aging clock near the theoretical limit of accuracy. Aging Cell, 20 (3). HOBOKEN: WILEY. ISSN 1474-9726

Mueller, Michael M., Castells-Roca, Laia ORCID: 0000-0002-4604-9999, Babu, Vipin ORCID: 0000-0002-0001-8783, Ermolaeva, Maria A., Mueller, Roman-Ulrich, Frommolt, Peter ORCID: 0000-0002-1966-8014, Williams, Ashley B., Greiss, Sebastian ORCID: 0000-0001-9130-0831, Schneider, Jennifer I., Benzing, Thomas, Schermer, Bernhard ORCID: 0000-0002-5194-9000 and Schumacher, Bjoern (2014). DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage. Nat. Cell Biol., 16 (12). S. 1168 - 1192. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4679

Nakad, Rania and Schumacher, Bjoern (2016). DNA Damage Response and Immune Defense: Links and Mechanisms. Front. Genet., 7. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-8021

Nkuipou-Kenfack, Esther, Bhat, Akshay, Klein, Julie ORCID: 0000-0002-3279-0559, Jankowski, Vera, Mullen, William, Vlahou, Antonia ORCID: 0000-0003-3284-5713, Dakna, Mohammed, Koeck, Thomas, Schanstra, Joost P., Zuerbig, Petra, Rudolph, Karl L., Schumacher, Bjoern, Pich, Andreas and Mischak, Harald ORCID: 0000-0003-0323-0306 (2015). Identification of ageing-associated naturally occurring peptides in human urine. Oncotarget, 6 (33). S. 34106 - 34118. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Nkuipou-Kenfack, Esther, Koeck, Thomas, Mischak, Harald ORCID: 0000-0003-0323-0306, Pich, Andreas, Schanstra, Joost P., Zuerbig, Petra and Schumacher, Bjoern (2014). Proteome analysis in the assessment of ageing. Ageing Res. Rev., 18. S. 74 - 86. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-9649

Ou, Hui-Ling, Kim, Christine S., Uszkoreit, Simon, Wickstroem, Sara A. and Schumacher, Bjoern (2019). Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Dev. Cell, 50 (2). S. 167 - 192. CAMBRIDGE: CELL PRESS. ISSN 1878-1551

Ribezzo, Flavia, Shiloh, Yosef and Schumacher, Bjoern (2016). Systemic DNA damage responses in aging and diseases. Semin. Cancer Biol., 37-38. S. 26 - 36. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. ISSN 1096-3650

Rieckher, Matthias ORCID: 0000-0002-1945-9474, Bujarrabal, Arturo, Doll, Markus A., Soltanmohammadi, Najmeh and Schumacher, Bjoern (2018). A simple answer to complex questions: Caenorhabditis elegans as an experimental model for examining the DNA damage response and disease genes. J. Cell. Physiol., 233 (4). S. 2781 - 2791. HOBOKEN: WILEY. ISSN 1097-4652

Rieckher, Matthias ORCID: 0000-0002-1945-9474, Markaki, Maria, Princz, Andrea, Schumacher, Bjoern and Tavernarakis, Nektarios ORCID: 0000-0002-5253-1466 (2018). Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans. Cell Reports, 25 (1). S. 199 - 218. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Rive, Corvin, Reina, Giacomo ORCID: 0000-0002-8147-3162, Wagle, Prerana, Treossi, Emanuele, Palermo, Vincenzo, Bianco, Alberto, Gemma-Delogu, Lucia, Rieckher, Matthias ORCID: 0000-0002-1945-9474 and Schumacher, Bjoern (2019). Improved Biocompatibility of Amino-Functionalized Graphene Oxide in Caenorhabditis elegans. Small, 15 (45). WEINHEIM: WILEY-V C H VERLAG GMBH. ISSN 1613-6829

Schumacher, Bjoern and Krieg, Thomas M. (2021). The Aging Skin: From Basic Mechanisms to Clinical Applications. J. Invest. Dermatol., 141 (4). S. 949 - 951. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Schumacher, Bjoern, Pothof, Joris, Vijg, Jan and Hoeijmakers, Jan H. J. (2021). The central role of DNA damage in the ageing process. Nature, 592 (7856). S. 695 - 704. BERLIN: NATURE RESEARCH. ISSN 1476-4687

Schwer, Bjoern, Schumacher, Bjoern, Lombard, David B., Xiao, Cuiying, Kurtev, Martin V., Gao, Jun, Schneider, Jennifer I., Chai, Hua, Bronson, Roderick T., Tsai, Li-Huei, Deng, Chu-Xia and Alt, Frederick W. (2010). Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity. Proc. Natl. Acad. Sci. U. S. A., 107 (50). S. 21790 - 21795. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Soltanmohammadi, Najmeh, Wang, Siyao ORCID: 0000-0001-6249-5721 and Schumacher, Bjoern (2022). Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy. Nat. Commun., 13 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Torgovnick, Alessandro, Schiavi, Alfonso ORCID: 0000-0002-6563-8035, Shaik, Anjumara, Kassahun, Henok, Maglioni, Silvia ORCID: 0000-0001-5272-9264, Rea, Shane L., Johnson, Thomas E., Reinhardt, Hans C., Honnen, Sebastian ORCID: 0000-0002-7845-7807, Schumacher, Bjoern, Nilsen, Hilde and Ventura, Natascia (2018). BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans. EMBO Rep., 19 (12). HOBOKEN: WILEY. ISSN 1469-3178

Vaddavalli, Pavana Lakshmi and Schumacher, Bjoern (2022). The p53 network: cellular and systemic DNA damage responses in cancer and aging. Trends Genet., 38 (6). S. 598 - 613. LONDON: ELSEVIER SCIENCE LONDON. ISSN 1362-4555

Wang, Siyao, Meyer, David H. and Schumacher, Bjoern (2020). H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. Nat. Struct. Mol. Biol., 27 (12). S. 1165 - 1183. BERLIN: NATURE RESEARCH. ISSN 1545-9985

Wang, Siyao, Meyer, David H. ORCID: 0000-0002-5667-4720 and Schumacher, Bjoern (2023). Inheritance of paternal DNA damage by histone-mediated repair restriction. Nature, 613 (7943). S. 365 - 393. BERLIN: NATURE PORTFOLIO. ISSN 1476-4687

Williams, Ashley B., Heider, Felix, Messling, Jan-Erik ORCID: 0000-0003-3843-0041, Rieckher, Matthias ORCID: 0000-0002-1945-9474, Bloch, Wilhelm and Schumacher, Bjoern (2019). Restoration of Proteostasis in the Endoplasmic Reticulum Reverses an Inflammation-Like Response to Cytoplasmic DNA in Caenorhabditis elegans. Genetics, 212 (4). S. 1259 - 1279. BETHESDA: GENETICS SOCIETY AMERICA. ISSN 1943-2631

Williams, Ashley B. and Schumacher, Bjoern (2017). DNA damage responses and stress resistance: Concepts from bacterial SOS to metazoan immunity. Mech. Ageing Dev., 165. S. 27 - 33. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-6216

Williams, Ashley B. and Schumacher, Bjoern (2016). p53 in the DNA-Damage-Repair Process. Cold Spring Harb. Perspect. Med., 6 (5). COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT. ISSN 2157-1422

Wilson, David M., III, Rieckher, Matthias ORCID: 0000-0002-1945-9474, Williams, Ashley B. and Schumacher, Bjoern (2017). Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans. Nucleic Acids Res., 45 (16). S. 9467 - 9481. OXFORD: OXFORD UNIV PRESS. ISSN 1362-4962

Wolters, Stefanie, Ermolaeva, Maria A., Bickel, Jeremy S., Fingerhut, Jaclyn M., Khanikar, Jayshree, Chan, Raymond C. and Schumacher, Bjoern (2014). Loss of Caenorhabditis elegans BRCA1 Promotes Genome Stability During Replication in smc-5 Mutants. Genetics, 196 (4). S. 985 - 1013. BETHESDA: GENETICS SOCIETY AMERICA. ISSN 1943-2631

da Silva, Paulo F. L. and Schumacher, Bjoern (2021). Principles of the Molecular and Cellular Mechanisms of Aging. J. Invest. Dermatol., 141 (4). S. 951 - 961. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747