Universität zu Köln

2024

Zheng, Ruiyuan ORCID: 0000-0002-7594-3869 (2024). Cell-to-cell transcriptional remodelling: a nuclear role for myeloperoxidase (MPO) in endothelial inflammation. PhD thesis, Universität zu Köln.

Gries, Raphael ORCID: 0000-0003-2392-388X (2024). Deciphering Novel Modes of Action of Lead Compounds with Antibacterial or Anti virulence Activity against Mycobacterium tuberculosis. PhD thesis, Universität zu Köln.

Schenk, Julia Katharina (2024). Cytokine-producing peripheral blood mononuclear cells (PBMCs) for discrimination of vertebral osteomyelitis and degenerative spinal diseases. PhD thesis, Universität zu Köln.

Peltier, Manon ORCID: 0009-0008-3832-4111 (2024). Effect of D-aspartate and storage temperature on cryopreserved sperm quality and fertility in mice. PhD thesis, Universität zu Köln.

Savcigil, Deniz Pinar ORCID: 0000-0002-9217-5582 (2024). Identification and Characterisation of Novel Mechanisms Regulating TNF-Induced Cell Death. PhD thesis, Universität zu Köln.

2023

Buchholz, Sarah ORCID: 0000-0002-3636-1364 (2023). Investigating human TAU isoform-specific functions and their toxicity in Alzheimer's disease and related tauopathies. PhD thesis, Universität zu Köln.

Nisar, Hasan (2023). Hypoxia-Induced Radioresistance in Human Non-Small Cell Lung Carcinoma Cell Lines. PhD thesis, Universität zu Köln.

Delle Vedove, Andrea ORCID: 0000-0003-4771-9808 (2023). Identification and Functional Assessment of Novel Neuromuscular Disease-Causing Genes. PhD thesis, Universität zu Köln.

Eisenack, Tom Joshua ORCID: 0000-0003-4829-4696 and Trentini, Débora Broch ORCID: 0000-0002-2541-4707 (2023). Ending a bad start: Triggers and mechanisms of co-translational protein degradation. Frontiers in Molecular Biosciences, 9. p. 1089825. Frontiers. ISSN 2296-889X

Voelkl, Kerstin ORCID: 0000-0002-4182-0764, Gutiérrez-Ángel, Sara, Keeling, Sophie ORCID: 0000-0002-6413-2550, Koyuncu, Seda ORCID: 0000-0001-7937-3974, da Silva Padilha, Miguel ORCID: 0000-0001-8141-7163, Feigenbutz, Dennis, Arzberger, Thomas, Vilchez, David ORCID: 0000-0002-0801-0743, Klein, Rüdiger ORCID: 0000-0002-3109-0163 and Dudanova, Irina ORCID: 0000-0003-1052-8485 (2023). Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease. Life Science Alliance, 6 (11). e202302018. EMBO Press. ISSN 2575-1077

Hirani, Dharmesh V. ORCID: 0000-0002-3907-0917, Thielen, Florian, Mansouri, Siavash, Danopoulos, Soula, Vohlen, Christina, Haznedar-Karakaya, Pinar, Mohr, Jasmine, Wilke, Rebecca, Selle, Jaco ORCID: 0000-0002-4981-0931, Grosch, Thomas, Mizik, Ivana ORCID: 0000-0002-3440-9133, Odenthal, Margarete ORCID: 0000-0002-2424-0960, Alvira, Cristina M., Kuiper-Makris, Celien ORCID: 0000-0002-7940-9612, Pryhuber, Gloria S., Pallasch, Christian P. ORCID: 0000-0001-5675-6905, van Koningsbruggen-Rietschel, Silke ORCID: 0000-0002-2222-4238, Al-Alam, Denise, Seeger, Werner, Savai, Rajkumar, Dötsch, Jörg ORCID: 0000-0003-1529-7647 and Alejandre Alcazar, Miguel Angel ORCID: 0000-0002-3176-0411 (2023). CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia. Inflammation and Regeneration, 43 (1). p. 52. Springer Nature. ISSN 1880-8190

Tschernoster, Nikolai ORCID: 0000-0002-6058-9342, Erger, Florian ORCID: 0000-0002-2768-1702, Kohl, Stefan, Reusch, Björn ORCID: 0000-0002-8963-6835, Wenzel, Andrea ORCID: 0009-0005-3280-0947, Walsh, Stephen, Thiele, Holger ORCID: 0000-0003-4495-4597, Becker, Christian ORCID: 0009-0002-2964-4486, Franitza, Marek, Bartram, Malte P., Kömhoff, Martin, Schumacher, Anna-Lena ORCID: 0000-0001-7739-486X, Kukat, Christian ORCID: 0000-0003-1508-0229, Borodina, Tatiana, Quedenau, Claudia, Nürnberg, Peter ORCID: 0000-0002-7228-428X, Rinschen, Markus M, Driller, Jan H., Pedersen, Bjørn P., Schlingmann, Karl P., Hüttel, Bruno ORCID: 0000-0001-7165-1714, Bockenhauer, Detlef, Beck, Bodo Bernhard ORCID: 0000-0003-0495-7670 and Altmüller, Janine ORCID: 0000-0003-4372-1521 (2023). Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions. Genome Medicine, 15 (1). p. 62. Springer Nature. ISSN 1756-994X

Reusch, Björn ORCID: 0000-0002-8963-6835 (2023). MAGED2: the gene associated with Bartter syndrome type 5 is a key regulator of Gαs signalling in the developing kidney. PhD thesis, Universität zu Köln.

Samehni, Mohamad (2023). Effects of the missense mutation (A263V) in the SCN2A gene on hippocampal and entorhinal cortex c-Fos expression in 7-day-old mice. PhD thesis, Universität zu Köln.

Thelen, Martin Andreas ORCID: 0000-0002-2785-9726 (2023). Endogenous antigen-specific T and B cell immune responses in cancer and invasive infections are frequent, but often limited by potentially targetable immune escape mechanisms. PhD thesis, Universität zu Köln.

Muinos-Buehl, A. (2023). Development of antisense oligonucleotide combinatorial therapies for spinal muscular atrophy (SMA). PhD thesis, Universität zu Köln.

Zeißler, Eva-Carina (2023). The potential of cytokines as diagnostic markers for vertebral osteomyelitis. PhD thesis, Universität zu Köln.

2022

Matin, Mahsa ORCID: 0000-0001-7954-6863 (2022). Modulating angiogenic balance to establish novel treatment strategies and a disease model for preeclampsia. PhD thesis, Universität zu Köln.

Pachano, Tomas ORCID: 0000-0003-2823-7715 (2022). Orphan CpG islands dictate the compatibility between poised enhancers and their target genes. PhD thesis, Universität zu Köln.

Theobald, Sebastian J ORCID: 0000-0001-7042-8326, Simonis, Alexander ORCID: 0000-0003-2945-9897, Mudler, Julie M ORCID: 0000-0003-1378-9648, Göbel, Ulrike, Acton, Richard ORCID: 0000-0002-2574-9611, Kohlhas, Viktoria ORCID: 0000-0001-8133-1001, Albert, Marie‐Christine, Hellmann, Anna‐Maria, Malin, Jakob J ORCID: 0000-0002-2989-0436, Winter, Sandra, Hallek, Michael ORCID: 0000-0002-7425-4455, Walczak, Henning ORCID: 0000-0002-6312-4591, Nguyen, Phuong‐Hien ORCID: 0000-0002-3249-7264, Koch, Manuel ORCID: 0000-0002-2962-7814 and Rybniker, Jan ORCID: 0000-0001-8351-2690 (2022). Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS‐CoV‐2 mRNA vaccination. EMBO Molecular Medicine, 14 (8). e15888. EMBO Press. ISSN 1757-4676

Grether, Nicolai B., Napravnik, Felix, Imhof, Thomas ORCID: 0000-0002-0554-7617, Linke, Reinhold P., Bräsen, Jan H., Schmitz, Jessica, Dohrn, Maike, Schneider, Christian, Svačina, Martin K. R. ORCID: 0000-0001-8166-5132, Stetefeld, Jörg, Koch, Manuel ORCID: 0000-0002-2962-7814 and Lehmann, Helmar C. ORCID: 0000-0001-6205-2293 (2022). Amyloidogenicity assessment of transthyretin gene variants. Annals of Clinical and Translational Neurology, 9 (8). pp. 1252-1263. Wiley. ISSN 2328-9503

Ravanelli, Sonia ORCID: 0000-0002-8511-9339, Li, Qiaochu ORCID: 0000-0001-8032-9110, Annibal, Andrea ORCID: 0000-0003-4311-5417, Trifunovic, Aleksandra ORCID: 0000-0002-5472-3517, Antebi, Adam ORCID: 0000-0002-7241-3029 and Hoppe, Thorsten ORCID: 0000-0002-4734-9352 (2022). Reprograming of proteasomal degradation by branched chain amino acid metabolism. Aging Cell, 21 (12). Wiley. ISSN 1474-9718

Bender, Niklas, Hennes, Marc ORCID: 0000-0002-6592-9297 and Maier, Berenike ORCID: 0000-0001-6971-9927 (2022). Mobility of extracellular DNA within gonococcal colonies. Biofilm, 4. p. 100078. Elsevier. ISSN 2590-2075

Dewald, Felix, Suárez, Isabelle ORCID: 0000-0002-9863-9675, Johnen, Ronja ORCID: 0000-0002-5150-5266, Grossbach, Jan ORCID: 0000-0002-9394-5665, Moran-Tovar, Roberto ORCID: 0000-0002-6291-9376, Steger, Gertrud ORCID: 0000-0002-0581-8122, Joachim, Alexander ORCID: 0000-0001-6724-0015, Rubio, Gibran Horemheb ORCID: 0000-0002-9529-9804, Fries, Mira, Behr, Florian, Kley, Joao ORCID: 0000-0002-7207-3714, Lingnau, Andreas, Kretschmer, Alina ORCID: 0000-0002-6323-1928, Gude, Carina, Baeza-Flores, Guadelupe, del Valle, David Laveaga, Roblero-Hernandez, Alberto, Magana-Cerino, Jesus, Hernandez, Adriana Torres, Ruiz-Quinones, Jesus ORCID: 0000-0002-3723-333X, Schega, Konstantin ORCID: 0000-0002-6297-7947, Linne, Viktoria, Junker, Lena, Wunsch, Marie ORCID: 0000-0002-6570-1831, Heger, Eva ORCID: 0000-0001-7625-5139, Knops, Elena ORCID: 0000-0001-7398-3026, Di Cristanziano, Veronica ORCID: 0000-0003-1604-8386, Meyer, Meike ORCID: 0000-0002-5708-3981, Hünseler, Christoph ORCID: 0000-0002-3086-8201, Weber, Lutz T., Lüers, Jan-Christoffer ORCID: 0000-0002-8273-2234, Quade, Gustav, Wisplinghoff, Hilmar, Tiemann, Carsten, Zotz, Rainer, Jomaa, Hassan, Pranada, Arthur ORCID: 0000-0003-2111-9011, Herzum, Ileana, Cullen, Paul, Schmitz, Franz-Josef, Philipsen, Paul, Kirchner, Georg, Knabbe, Cornelius, Hellmich, Martin ORCID: 0000-0001-5174-928X, Buess, Michael, Wolff, Anna, Kossow, Annelene, Niessen, Johannes, Jeworutzki, Sebastian ORCID: 0000-0002-2671-5253, Schräpler, Jörg-Peter, Lässig, Michael ORCID: 0000-0002-3575-6719, Dötsch, Jörg ORCID: 0000-0003-1529-7647, Fätkenheuer, Gerd ORCID: 0000-0002-5054-1871, Kaiser, Rolf ORCID: 0000-0002-2640-2548, Beyer, Andreas, Rybniker, Jan ORCID: 0000-0001-8351-2690 and Klein, Florian ORCID: 0000-0003-1376-1792 (2022). Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children. Nature Communications, 13 (1). p. 3640. Springer Nature. ISSN 2041-1723

Trojan, Tobias, Alejandre Alcázar, Miguel Angel ORCID: 0000-0002-3176-0411, Fink, Gereon R. ORCID: 0000-0002-8230-1856, Thomassen, Jan Christoph, von Maessenhausen, Maxine, Rietschel, Ernst ORCID: 0000-0001-7899-8833, Schneider, Peter M. ORCID: 0000-0003-0744-2349 and van Koningsbruggen-Rietschel, Silke ORCID: 0000-0002-2222-4238 (2022). The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis. BMC Pulmonary Medicine, 22 (1). p. 183. Springer Nature. ISSN 1471-2466

Imai, Takashi, Van, Trieu My, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Polykratis, Apostolos ORCID: 0000-0001-6720-3302 (2022). Smooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE−/− mice. Scientific Reports, 12 (1). p. 12538. Springer Nature. ISSN 2045-2322

Meeser, Alina, Bartenhagen, Christoph ORCID: 0000-0002-2522-1454, Werr, Lisa Hanna ORCID: 0000-0002-3697-4136, Hellmann, Anna-Maria, Kahlert, Yvonne, Hemstedt, Nadine, Nürnberg, Peter ORCID: 0000-0002-7228-428X, Altmüller, Janine, Ackermann, Sandra ORCID: 0000-0002-5869-7344, Hero, Barbara ORCID: 0000-0003-4129-890X, Simon, Thorsten ORCID: 0000-0002-3425-8451, Peifer, Martin ORCID: 0000-0002-5243-5503, Fischer, Matthias ORCID: 0000-0003-1363-1242 and Rosswog, Carolina ORCID: 0000-0002-8855-6198 (2022). Reliable assessment of telomere maintenance mechanisms in neuroblastoma. Cell & Bioscience, 12 (1). p. 160. Springer Nature. ISSN 2045-3701

Liebsch, Filip ORCID: 0000-0002-0955-8065, Eggersmann, Fynn R. ORCID: 0000-0001-7777-4424, Merkler, Yvonne ORCID: 0000-0002-4281-9060, Kloppenburg, Peter ORCID: 0000-0002-4554-404X and Schwarz, Günter (2022). Automated Image Analysis Reveals Different Localization of Synaptic Gephyrin C4 Splice Variants. eneuro, 10 (1). ENEURO.0102-22.2022. Society for Neuroscience; HighWie Press. ISSN 2373-2822

Youla, Alpha Oumar (2022). Retrospektive Betrachtung der Sportverletzungen bei der Ausübung der Kampfsportarten Mixed Martial Arts und Kickboxen. PhD thesis, Universität zu Köln.

2021

Thelen, Maximilian Paul ORCID: 0000-0003-1714-1179 (2021). Defective Mitochondria Contribute to Impaired Translation in Spinal Muscular Atrophy. PhD thesis, Universität zu Köln.

Hauser, Christoph (2021). Neue Assays zur Charakterisierung der Transamidaseaktivität und der GTP-Bindungsfunktion von Transglutaminase 2. PhD thesis, Universität zu Köln.

Bleckwehl, Tore (2021). The relevance of the epigenetic features of enhancers for germline competence. PhD thesis, Universität zu Köln.

2019

Bartusel, Michaela (2019). Disruption of neural crest enhancer landscapes as an etiological mechanism for human neurocristopathies. PhD thesis, Universität zu Köln.

Golumba-Nagy, Viktória (2019). CAR modified T cells resist TGF-b mediated repression through engineered IL-7 triggered IL-2 signaling. PhD thesis, Universität zu Köln.

2018

Brant, Lilija (2018). Exploiting native forces to capture chromosome conformation in mammalian cell nuclei. PhD thesis, Universität zu Köln.

2017

Schöllhorn, Laura (2017). Anti-lymphangiogenic compounds as novel treatment strategies in dry eye disease. PhD thesis, Universität zu Köln.

2016

Kaczmarek, Anna (2016). Analysis of reduced Neurocalcin delta (NCALD) as a protective modifier in mouse models of Spinal Muscular Atrophy (SMA). PhD thesis, Universität zu Köln.

Peters, Miriam (2016). Combined therapie of SMN-ASO and Plastin 3 overexpression rescues severe SMA in mice. PhD thesis, Universität zu Köln.

Scholz, Rebecca (2016). Microglia as therapeutic targets in retinal degeneration: role of translocator protein (18 κDa) (TSPO) and minocycline. PhD thesis, Universität zu Köln.

Aslanidis, Alexander (2016). Characterization of photoreceptor gene regulation and modulation of microglial reactivity in the retina. PhD thesis, Universität zu Köln.

Schnödt, Maria Angelika (2016). Improving safety and establishing episomal maintenance of Adeno-associated viral vectors. PhD thesis, Universität zu Köln.

Hos, Deniz (2016). The Contribution of Macrophages to Inflammatory Corneal Lymphangiogenesis. PhD thesis, Universität zu Köln.

2015

Dibué-Adjei, Maxine (2015). Mechanisms of the Cav2.3 Calcium Channel’s Role in Epileptogenesis and Antiepileptic Pharmacotherapy. PhD thesis, Universität zu Köln.

2014

Schmied, Sabine (2014). Characterization of tumor-antigen-specific T cells - insights into WT1- and HPV16-specific T cell repertoires. PhD thesis, Universität zu Köln.

Kocak, Hayriye (2014). Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma. PhD thesis, Universität zu Köln.

Chatterjee, Sampurna (2014). Targeting the tumor blood vessels: VEGFR2 as a Biomarker and Therapeutic Target in Non Small Cell Lung Cancer. PhD thesis, Universität zu Köln.

Lichtenauer, Urs Daniel (2014). Adrenal progeny and factors of adrenal differentiation. PhD thesis, Universität zu Köln.

Willkomm, Lena (2014). The Effects of Lactate on Skeletal Muscle. PhD thesis, Universität zu Köln.

Sallach, Jessica (2014). Exploiting high-throughput screens to optimize Adeno-Associated Viral Vectors for gene transfer into primary human keratinocytes. PhD thesis, Universität zu Köln.

Chatterjee, Sampurna (2014). Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer. Cancer Research.

2013

Dafinger, Claudia (2013). Molekulare Pathogenese des Joubert-Syndroms - Die Rolle des Proteins KIF7. PhD thesis, Universität zu Köln.

Chatterjee, Sampurna and Heukamp, Lukas (2013). Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. JCI. pp. 1732-1740.

2012

Esser, Knud (2012). Das Hepatitis B Virus folgt dem Transport der neutralen Lipide in die Leber und in die Hepatozyten, um seine Wirtszelle zu erreichen und zu infizieren. PhD thesis, Universität zu Köln.

Rabenhorst, Anja (2012). The role of mast cells in the microenvironment of tumors. PhD thesis, Universität zu Köln.