Universität zu Köln

2020

Schwarzer, Robin, Jiao, Huipeng, Wachsmuth, Laurens, Tresch, Achim and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity, 52.

Schwarzer, Robin, Laurien, Lucie and Pasparakis, Manolis (2020). New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8. Current Opinion in Cell Biology, 63. pp. 186-193. ISSN 09550674

Pereira Correia, Andreia Cláudia (2020). Giants of immunity: Uncovering a role for Atf3 in Multinucleated Giant Cell formation. Thesis Abstract, Universität zu Köln.

Gerbracht, Jennifer Victoria ORCID: 0000-0002-3377-4649 (2020). Analysis of post-transcriptional gene expression modulated by mRNA stability and RNA-binding proteins in human cells. PhD thesis, Universität zu Köln.

Mittenbühler, Melanie Joyce (2020). The Impact of Hepatic FTO on the Initiation and Development of Hepatocellular Carcinoma. Thesis Abstract, Universität zu Köln.

Wolf, Anne (2020). Role of translocator protein (18 kDa) (TSPO) in retinal phagocytes in a mouse model of age-related macular degeneration (AMD). PhD thesis, Universität zu Köln.

2019

Schütter, Lena-Sophie (2019). The Antiviral RNAi Pathway Maintains ER Homeostasis by Degrading mRNAs of Secretory Proteins. Thesis Abstract, Universität zu Köln.

Thelen, Eva Lisa Diana (2019). Deciphering the Role Scaffold Protein NEDD9 in Chronic Lymphocytic Leukemia Pathogenesis. Thesis Abstract, Universität zu Köln.

Polykratis, A, Martens, A, Eren, RO, Shirasaki, Y, Yamagishi, M, Yamaguchi, Y, Uemura, S, Miura, M, Holzmann, B, Kollias, G, Armaka, M, van Loo, G and Pasparakis, M (2019). A20 Prevents Inflammasome-Dependent Arthritis by Inhibiting Macrophage Necroptosis Through Its ZnF7 Ubiquitin-Binding Domain. Nature Cell Biology, 6 (21). pp. 731-742.

Kilinc, Merve (2019). Learning from the fly: Oncogenic JNK signalling is linked to Hippo pathway via its downstream effectors Cheerio and Ftz-F1. Thesis Abstract, Universität zu Köln.

Schuster, Ramona (2019). Regulation of Mitochondrial Outer Membrane Fusion by Ubiquitylation of Fzo1. Thesis Abstract, Universität zu Köln.

Rehorst, Wiebke Adele (2019). Muscle-Secreted Factors in Spinal Muscular Atrophy: CTRP3 at the Interface of Muscle and Neuron. Thesis Abstract, Universität zu Köln.

Altekoester, Ann-Kristin (2019). Decoding the transcriptional landscape of Nkx2-5 in heart development and disease. PhD thesis, Universität zu Köln.

Tadepalle, Nimesha (2019). Spastin-mediated microtubule severing controls lipid droplet biogenesis and distribution. Thesis Abstract, Universität zu Köln.

Akhtar-Schäfer, Isha (2019). Role of the complement system and HtrA1 in microglia and age-related macular degeneration. PhD thesis, Universität zu Köln.

Wirtz, Johannes M. (2019). Coalescent Theory and Yule Trees in time and space. PhD thesis, Universität zu Köln.

Schwarzer, Robin (2019). In vivo function of FADD and Caspase-8 in the intestinal epithelium. Thesis Abstract, Universität zu Köln.

Hermanns, Thomas ORCID: 0000-0001-5350-7479 (2019). Structural and Biochemical Characterization of the ZUFSP Deubiquitinase Family. Thesis Abstract, Universität zu Köln.

Nolte, Hanns Hendrik (2019). Instant Clue aided multilayered proteomic analysis reveals a new member of the Insulin Signalling Pathway - Fbxo30. Thesis Abstract, Universität zu Köln.

Albert, Marie-Christine (2019). Ubiquitylation of NOXA in DNA Damage Response. Thesis Abstract, Universität zu Köln.

Hermanns, Thomas ORCID: 0000-0001-5350-7479 and Hofmann, Kay (2019). Bacterial DUBs: deubiquitination beyond the seven classes. Biochem. Soc. Trans., 47. S. 1857 - 1867. LONDON: PORTLAND PRESS LTD. ISSN 1470-8752

Krishna-Subramanian, Santosh, Singer, Stephan, Armaka, Marietta, Banales, Jesus M., Holzer, Kerstin, Schirmacher, Peter, Walczak, Henning ORCID: 0000-0002-6312-4591, Kollias, George, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kondylis, Vangelis ORCID: 0000-0002-6970-8731 (2019). RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ., 26 (12). S. 2710 - 2727. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

Fritsch, Melanie, Gunther, Saskia D., Schwarzer, Robin, Albert, Marie-Christine, Schorn, Fabian, Werthenbach, J. Paul, Schiffmann, Lars M., Stair, Neil, Stocks, Hannah ORCID: 0000-0002-4129-5138, Seeger, Jens M., Lamkanfi, Mohamed, Kroenke, Martin, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kashkar, Hamid (2019). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature, 575 (7784). S. 683 - 700. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

MacVicar, Thomas, Ohba, Yohsuke, Nolte, Hendrik, Mayer, Fiona Carola, Tatsuta, Takashi, Sprenger, Hans-Georg, Lindner, Barbara, Zhao, Yue, Li, Jiahui, Bruns, Christiane, Krueger, Marcus, Habich, Markus, Riemer, Jan, Schwarzer, Robin, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Henschke, Sinika, Bruening, Jens C., Zamboni, Nicola ORCID: 0000-0003-1271-1021 and Langer, Thomas (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature, 575 (7782). S. 361 - 386. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Kondylis, Vangelis ORCID: 0000-0002-6970-8731 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2019). RIP Kinases in Liver Cell Death, Inflammation and Cancer. Trends Mol. Med, 25 (1). S. 47 - 64. OXFORD: ELSEVIER SCI LTD. ISSN 1471-499X

Priem, Dario ORCID: 0000-0002-2527-1101, Devos, Michael ORCID: 0000-0001-9522-6026, Druwe, Sarah, Martens, Arne, Slowicka, Karolina, Ting, Adrian T., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Declerq, Wim, Vandenabeele, Peter, van Loo, Geert and Bertrand, Mathieu J. M. (2019). A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell Death Dis., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-4889

Seenivasan, Ramkumar, Hermanns, Thomas ORCID: 0000-0001-5350-7479, Blyszcz, Tamara, Lammers, Michael ORCID: 0000-0003-4168-4640, Praefcke, Gerrit J. K. and Hofmann, Kay (2019). Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome. Hum. Mol. Genet., 28 (17). S. 2862 - 2874. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Eftychi, Christina, Schwarzer, Robin, Vlantis, Katerina, Wachsmuth, Laurens, Basic, Marijana, Wagle, Prerana, Neurath, Markus F., Becker, Christoph, Bleich, Andre and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2019). Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity, 51 (2). S. 367 - 385. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Voigt, Franka, Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Boehm, Volker ORCID: 0000-0001-7588-9842, Horvathova, Ivana, Eglinger, Jan ORCID: 0000-0001-7234-1435, Chao, Jeffrey A. and Gehring, Niels H. (2019). Detection and quantification of RNA decay intermediates using XRN1-resistant reporter transcripts. Nat. Protoc., 14 (5). S. 1603 - 1634. LONDON: NATURE PUBLISHING GROUP. ISSN 1750-2799

Graeb, Jessica, Suarez, Isabelle, van Gumpel, Edeltraud, Winter, Sandra, Schreiber, Fynn, Esser, Anna, Hoelscher, Christoph, Fritsch, Melanie, Herb, Marc ORCID: 0000-0002-7533-0288, Schramm, Michael, Wachsmuth, Laurens, Pallasch, Christian, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kashkar, Hamid and Rybniker, Jan (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Liccardi, Gianmaria, Garcia, Laura Ramos, Tenev, Tencho, Annibaldi, Alessandro ORCID: 0000-0002-0346-4340, Legrand, Arnaud J., Robertson, David, Feltham, Rebecca, Anderton, Holly ORCID: 0000-0003-3913-9686, Darding, Maurice, Peltzer, Nieves ORCID: 0000-0002-4134-5852, Dannappel, Marius, Schunke, Hannah, Fava, Luca L., Haschka, Manuel D., Glatter, Timo, Nesvizhskii, Alexey, Schmidt, Alexander, Harris, Philip A., Bertin, John, Gough, Peter J., Villunger, Andreas, Silke, John ORCID: 0000-0002-7611-5774, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Bianchi, Katiuscia and Meier, Pascal ORCID: 0000-0003-2760-6523 (2019). RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol. Cell, 73 (3). S. 413 - 436. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Koliaraki, Vasiliki ORCID: 0000-0003-1694-6987, Chalkidi, Niki, Henriques, Ana, Tzaferis, Christos, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Waisman, Ari, Muller, Werner ORCID: 0000-0002-1297-9725, Hackam, David J., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kollias, George (2019). Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis. Cell Reports, 26 (3). S. 536 - 550. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

2018

Euteneuer, Anna Maria (2018). Involvement of estrogen receptor in transcriptional regulation of renal organic anion transporter 1 (OAT1) and OAT3. Thesis Abstract, Universität zu Köln.

Peek, Irina (2018). Functional and structural characterization of the Drosophila gene smallish during epithelial morphogenesis. PhD thesis, Universität zu Köln.

Sang, Qing (2018). Molecular-genetic analysis of endogenous flowering pathways and shoot meristem development in Arabidopsis thaliana. Thesis Abstract, Universität zu Köln.

Knittel, Gero Thomas (2018). An autochthonous mouse model of MYD88 p.L265P- and BCL2-driven diffuse large B cell lymphoma. Thesis Abstract, Universität zu Köln.

Murru, Sara (2018). The role of astrocytes in neurological phenotypes associated with deficiency of the m-AAA protease. PhD thesis, Universität zu Köln.

Dieris, Milan (2018). Amine detection in aquatic organisms: receptor evolution, neuronal circuits and behavior in the model organism zebrafish. PhD thesis, Universität zu Köln.

Sharma, Kanika (2018). Olfactory coding in vertebrates: a novel tuning mechanism for receptor affinity and evolution of the olfactory receptor repertoire. PhD thesis, Universität zu Köln.

Klassmann, Alexander (2018). Adaptations of neutrality tests. PhD thesis, Universität zu Köln.

Fragel, Susann Marlies (2018). Functional and structural characterization of LeuO, a pleiotropic LysR-type transcription regulator in Escherichia coli. PhD thesis, Universität zu Köln.

Franqueira Cardoso Lopes, Amanda (2018). A Caenorhabditis elegans model for Cockayne Syndrome. Thesis Abstract, Universität zu Köln.

Rangarajan, Aathmaja Anandhi (2018). Interference of transcription on H-NS mediated repression in Escherichia coli. PhD thesis, Universität zu Köln.

Mendoza-Ferreira, Natalia (2018). Uncovering and Functional Analysis of Novel Genes and Potential Genetic Modifiers for Neuromuscular Disorders. PhD thesis, Universität zu Köln.

Ostermann, Anna Lena (2018). IEC-specific Insulin Resistance Impairs Gut Barrier Function and Promotes Colitis-associated Cancer. Thesis Abstract, Universität zu Köln.

Thier, Katharina (2018). Die Beteiligung zellulärer Rezeptoren am Eintritt von Herpes simplex Virus 1 in Haut und Mundschleimhaut. Thesis Abstract, Universität zu Köln.

Mylonas, Konstantinos (2018). Elucidating the molecular mechanisms conferred by the histone chaperone FACT. PhD thesis, Universität zu Köln.

Proksch, Lucie (2018). The role of microRNAs in aging-related proteolytic pathways in Caenorhabditis elegans. Thesis Abstract, Universität zu Köln.

Günther, Saskia Diana (2018). Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through LPS. Thesis Abstract, Universität zu Köln.

Schumacher, Simon (2018). The role of the ERLIN complex in regulating the morphology of the endoplasmic reticulum. Thesis Abstract, Universität zu Köln.

Sprenger, Hans-Georg (2018). The physiological role of the mitochondrial proteases YME1L and OMA1 in the nervous system. Thesis Abstract, Universität zu Köln.

Rauscher, Martina (2018). Topology of genealogical trees - theory and application. PhD thesis, Universität zu Köln.

D'Cruz, Akshay A., Speir, Mary, Bliss-Moreau, Meghan, Dietrich, Sylvia, Chen, Alyce A., Gavillet, Mathilde, Lawlor, Kate E., Vince, James E., Kelliher, Michelle, Hakem, Razq, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Williams, David A., Ericsson, Maria and Croker, Ben A. (2018). Padi4 Regulates NET Formation and Inflammatory Cell Death Downstream of Mlkl. Blood, 132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Aden, Konrad ORCID: 0000-0003-3482-7316, Tran, Florian, Ito, Go, Sheibani-Tezerji, Raheleh, Lipinski, Simone, Kuiper, Jan W., Tschurtschenthaler, Markus ORCID: 0000-0002-0060-4790, Saveljeva, Svetlana, Bhattacharyya, Joya ORCID: 0000-0003-1745-4167, Haesler, Robert, Bartsch, Kareen, Luzius, Anne, Jentzsch, Marlene, Falk-Paulsen, Maren, Stengel, Stephanie T., Welz, Lina, Schwarzer, Robin, Rabe, Bjoern, Barchet, Winfried ORCID: 0000-0002-6745-6606, Krautwald, Stefan ORCID: 0000-0001-7768-2132, Hartmann, Gunther ORCID: 0000-0003-1021-2018, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Blumberg, Richard S., Schreiber, Stefan, Kaser, Arthur and Rosenstiel, Philip ORCID: 0000-0002-9692-8828 (2018). ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. J. Exp. Med., 215 (11). S. 2868 - 2887. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Boehm, Volker ORCID: 0000-0001-7588-9842, Britto-Borges, Thiago, Steckelberg, Anna-Lena ORCID: 0000-0001-7988-9946, Singh, Kusum K., Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Gueney, Elif, Blazquez, Lorea, Altmueller, Janine, Dieterich, Christoph and Gehring, Niels H. (2018). Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity. Mol. Cell, 72 (3). S. 482 - 503. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Taraborrelli, Lucia, Peltzer, Nieves ORCID: 0000-0002-4134-5852, Montinaro, Antonella, Kupka, Sebastian, Rieser, Eva, Hartwig, Torsten, Sarr, Aida, Darding, Maurice, Draber, Peter ORCID: 0000-0001-8658-4614, Haas, Tobias L., Akarca, Ayse, Marafioti, Teresa ORCID: 0000-0003-1223-6275, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Bertin, John, Gough, Peter J., Bouillet, Philippe ORCID: 0000-0002-9012-6058, Strasser, Andreas ORCID: 0000-0002-5020-4891, Leverkus, Martin, Silke, John ORCID: 0000-0002-7611-5774 and Walczak, Henning ORCID: 0000-0002-6312-4591 (2018). LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

D'Cruz, Akshay A., Speir, Mary ORCID: 0000-0003-0384-886X, Bliss-Moreau, Meghan, Dietrich, Sylvia, Wang, Shu, Chen, Alyce A., Gavillet, Mathilde, Al-Obeidi, Arshed, Lawlor, Kate E., Vince, James E., Kelliher, Michelle A., Hakem, Razq, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Williams, David A., Ericsson, Maria and Croker, Ben A. (2018). The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils. Sci. Signal., 11 (546). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1937-9145

Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle (2018). Connecting immune deficiency and inflammation. Science, 361 (6404). S. 756 - 758. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

Vreka, Malamati, Lilis, Ioannis, Papageorgopoulou, Maria, Giotopoulou, Georgia A., Lianou, Marina, Giopanou, Ioanna ORCID: 0000-0003-4393-7517, Kanellakis, Nikolaos I., Spella, Magda, Agalioti, Theodora ORCID: 0000-0002-5898-2751, Armenis, Vasileios, Goldmann, Torsten ORCID: 0000-0002-1621-560X, Marwitz, Sebastian ORCID: 0000-0003-4920-5552, Yull, Fiona E., Blackwell, Timothy S., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Marazioti, Antonia and Stathopoulos, Georgios T. (2018). I kappa B Kinase alpha Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma. Cancer Res., 78 (11). S. 2939 - 2952. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Zelic, Matija, Roderick, Justine E., O'Donnell, Joanne A., Lehman, Jesse, Lim, Sung Eun, Janardhan, Harish P., Trivedi, Chinmay M., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2018). RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome. J. Clin. Invest., 128 (5). S. 2064 - 2076. ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 1558-8238

Pichlo, Christian ORCID: 0000-0002-3156-5667, Toelzer, Christine ORCID: 0000-0001-9984-5940, Chojnacki, Konrad ORCID: 0000-0002-9285-0904, Oecal, Sinan, Uthoff, Matthias ORCID: 0000-0002-6477-5505, Ruegenberg, Sabine, Hermanns, Thomas ORCID: 0000-0001-5350-7479, Schacherl, Magdalena ORCID: 0000-0002-5478-2509, Denzel, Martin S., Hofmann, Kay, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Baumann, Ulrich (2018). Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer. Acta Crystallogr. F-Struct. Biol. Commun., 74. S. 307 - 315. CHESTER: INT UNION CRYSTALLOGRAPHY. ISSN 2053-230X

Androulidaki, Ariadne, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2018). Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes. PLoS One, 13 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A., Abrams, John M., Adam, Dieter ORCID: 0000-0002-5668-5032, Agostinis, Patrizia ORCID: 0000-0003-1314-2115, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Annicchiarico-Petruzzelli, Margherita ORCID: 0000-0002-4717-4740, Antonov, Alexey V., Arama, Eli, Baehrecke, Eric H., Barlev, Nickolai A., Bazan, Nicolas G., Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Katiuscia, Blagosklonny, Mikhail V., Blomgren, Klas, Borner, Christoph, Boya, Patricia ORCID: 0000-0003-3045-951X, Brenner, Catherine, Campanella, Michelangelo, Candi, Eleonora, Carmona-Gutierrez, Didac ORCID: 0000-0001-7548-7771, Cecconi, Francesco, Chan, Francis K. -M., Chandel, Navdeep S., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Cohen, Gerald M., Conrad, Marcus ORCID: 0000-0003-1140-5612, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D'Angiolella, Vincenzo, Dawson, Ted M., Dawson, Valina L., De laurenzi, Vincenzo, De Maria, Ruggero ORCID: 0000-0003-2255-0583, Debatin, Klaus-Michael ORCID: 0000-0002-8397-1886, DeBerardinis, Ralph J., Deshmukh, Mohanish, Di Daniele, Nicola, Di Virgilio, Francesco ORCID: 0000-0003-3566-1362, Dixit, Vishva M., Dixon, Scott J., Duckett, Colin S., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Fimia, Gian Maria ORCID: 0000-0003-4438-3325, Fulda, Simone ORCID: 0000-0002-0459-6417, Garcia-Saez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis ORCID: 0000-0001-6319-8331, Golstein, Pierre ORCID: 0000-0003-1750-3483, Gottlieb, Eyal ORCID: 0000-0002-9770-0956, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich ORCID: 0000-0001-9454-2449, Gross, Atan, Hajnoczky, Gyorgy, Hardwick, J. Marie, Harris, Isaac S., Hengartner, Michael O., Hetz, Claudio, Ichijo, Hidenori, Jaattela, Marja ORCID: 0000-0001-5950-7111, Joseph, Bertrand, Jost, Philipp J. ORCID: 0000-0003-2454-0362, Juin, Philippe P., Kaiser, William J., Karin, Michael, Kaufmann, Thomas ORCID: 0000-0001-9906-874X, Kepp, Oliver ORCID: 0000-0002-6081-9558, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Knight, Richard A., Kumar, Sharad ORCID: 0000-0001-7126-9814, Lee, Sam W., Lemasters, John J., Levine, Beth, Linkermann, Andreas ORCID: 0000-0001-6287-9725, Lipton, Stuart A., Lockshin, Richard A., Lopez-Otin, Carlos ORCID: 0000-0001-6964-1904, Lowe, Scott W., Luedde, Tom, Lugli, Enrico, MacFarlane, Marion, Madeo, Frank, Malewicz, Michal, Malorni, Walter, Manic, Gwenola ORCID: 0000-0003-3759-8029, Marine, Jean-Christophe ORCID: 0000-0003-2433-9837, Martin, Seamus J., Martinou, Jean-Claude, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal ORCID: 0000-0003-2760-6523, Melino, Sonia, Miao, Edward A., Molkentin, Jeffery D., Moll, Ute M., Munoz-Pinedo, Cristina ORCID: 0000-0002-9120-664X, Nagata, Shigekazu ORCID: 0000-0001-9758-8426, Nunez, Gabriel, Oberst, Andrew, Oren, Moshe, Overholtzer, Michael, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Penninger, Josef M., Pereira, David M. ORCID: 0000-0003-0384-7592, Pervaiz, Shazib, Peter, Marcus E., Piacentini, Mauro ORCID: 0000-0003-2919-1296, Pinton, Paolo, Prehn, Jochen H. M., Puthalakath, Hamsa ORCID: 0000-0001-5178-1175, Rabinovich, Gabriel A., Rehm, Markus ORCID: 0000-0001-6149-9261, Rizzuto, Rosario, Rodrigues, Cecilia M. P., Rubinsztein, David C., Rudel, Thomas, Ryan, Kevin M., Sayan, Emre, Scorrano, Luca ORCID: 0000-0002-8515-8928, Shao, Feng, Shi, Yufang ORCID: 0000-0001-8964-319X, Silke, John ORCID: 0000-0002-7611-5774, Simon, Hans-Uwe ORCID: 0000-0002-9404-7736, Sistigu, Antonella, Stockwell, Brent R., Strasser, Andreas ORCID: 0000-0002-5020-4891, Szabadkai, Gyorgy, Tait, Stephen W. G., Tang, Daolin, Tavernarakis, Nektarios ORCID: 0000-0002-5253-1466, Thorburn, Andrew, Tsujimoto, Yoshihide, Turk, Boris ORCID: 0000-0002-9007-5764, Vanden Berghe, Tom, Vandenabeele, Peter ORCID: 0000-0002-6669-8822, Heiden, Matthew G. Vander, Villunger, Andreas, Virgin, Herbert W., Vousden, Karen H., Vucic, Domagoj, Wagner, Erwin F., Walczak, Henning ORCID: 0000-0002-6312-4591, Wallach, David, Wang, Ying, Wells, James A., Wood, Will, Yuan, Junying, Zakeri, Zahra, Zhivotovsky, Boris ORCID: 0000-0002-2238-3482, Zitvogel, Laurence, Melino, Gerry and Kroemer, Guido (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death Differ., 25 (3). S. 486 - 542. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

Hermanns, Thomas ORCID: 0000-0001-5350-7479, Pichlo, Christian ORCID: 0000-0002-3156-5667, Woiwode, Ilka, Klopffleisch, Karsten ORCID: 0000-0002-6977-1386, Witting, Katharina F., Ovaa, Huib ORCID: 0000-0002-0068-054X, Baumann, Ulrich and Hofmann, Kay (2018). A family of unconventional deubiquitinases with modular chain specificity determinants. Nat. Commun., 9. BERLIN: NATURE RESEARCH. ISSN 2041-1723

Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649 and Gehring, Niels H. (2018). The exon junction complex: structural insights into a faithful companion of mammalian mRNPs. Biochem. Soc. Trans., 46. S. 153 - 162. LONDON: PORTLAND PRESS LTD. ISSN 1470-8752

Armaka, Marietta, Ospelt, Caroline ORCID: 0000-0002-9151-4650, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kollias, George (2018). The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

O'Donnell, Joanne A., Lehman, Jesse, Roderick, Justine E., Martinez-Marin, Dalia ORCID: 0000-0002-5476-4618, Zelic, Matija, Doran, Ciara, Hermance, Nicole, Lyle, Stephen, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Fitzgerald, Katherine A., Marshak-Rothstein, Ann and Kelliher, Michelle A. (2018). Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity. J. Immunol., 200 (2). S. 737 - 749. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

2017

Isokallio, Marita (2017). The source and fate of mitochondrial DNA mutations using high-sensitivity next-generation sequencing technologies. PhD thesis, Universität zu Köln.

Wozny, Dorothee Charlotte (2017). Identification and Characterization of Seed Longevity Genes in Barley (Hordeum vulgare). PhD thesis, Universität zu Köln.

Cruz Molina, Sara de la (2017). Poised enhancers are key cis-regulatory elements during ESC differentiation whose activity is facilitated by Polycomb repressive complex 2. PhD thesis, Universität zu Köln.

Marx, Benjamin Raphael (2017). Mechanism of HPV8 mediated silencing of Syntenin-2 gene expression and modulation of nuclear phospholipid metabolism. Thesis Abstract, Universität zu Köln.

Bertsch, Sabine (2017). The role of the E3-ubiquitin ligase HUWE1 in podocyte signaling and homeostasis. Thesis Abstract, Universität zu Köln.

Jiao, Wenbiao (2017). High-quality genome assemblies of plant species using third generation genomic technologies and comprehensive genotypic characterization of Arabis inter-species introgression lines. PhD thesis, Universität zu Köln.

Lim, Radiance (2017). Regulation of endothelial Notch signalling by deubiquitinases. Thesis Abstract, Universität zu Köln.

Schneider, Svenja (2017). Identification and Characterization of Spinal Muscular Atrophy (SMA) Modifiers - Insights from Cellular and Vertebrate Disease Models. Thesis Abstract, Universität zu Köln.

Edifizi, Diletta (2017). A multidimensional omics analysis of the DNA damage response in Caenorhabditis elegans. PhD thesis, Universität zu Köln.

Schotik, Maria (2017). Elucidating the function of novel genes and molecular mechanisms involved in accelerated ageing. Thesis Abstract, Universität zu Köln.

Kohli, Priyanka (2017). Comprehensive analyses of the ciliary membrane-associated proteome identifies actin-binding proteins as novel components of primary cilia. Thesis Abstract, Universität zu Köln.

Shiriagin, Vladimir Vladimirovich (2017). Evolution and function of fish chemosensory receptors: Preadaptive expansion of bitter taste receptors in blind cavefish and analysis of an ancestral olfactory receptor gene in zebrafish. Thesis Abstract, Universität zu Köln.

Van, Trieu My (2017). The role of RIPK1 signaling in liver injury and cancer. PhD thesis, Universität zu Köln.

Martinez Carrera, Lilian Andrea (2017). Identification and functional characterization of BICD2 mutations causing SMALED2, a congenital dominant form of spinal muscular atrophy. PhD thesis, Universität zu Köln.

Lampe, Philipp Alexander (2017). Analysis of the function and activation of the metalloprotease OMA1. Thesis Abstract, Universität zu Köln.

Gutierrez, Saray (2017). S. Typhimurium evades macrophage defense by preventing glycolysis-regulated acidification of phagosomes. Thesis Abstract, Universität zu Köln.

Crispatzu, Giuliano (2017). Integrative approaches to high-throughput data in lymphoid leukemias (on transcriptomes, the whole-genome mutational landscape, flow cytometry and gene copy-number alterations). PhD thesis, Universität zu Köln.

Bozorg Nia, Shahrzad (2017). Topology of vertebrate olfactory receptor gene expression with particular emphasis on the V1R-related ora gene family. Thesis Abstract, Universität zu Köln.

Hassani, Mohamed Amine (2017). Experimental systems to explore the competitiveness of root-associated bacteria and its relevance for community establishment. PhD thesis, Universität zu Köln.

Ottens, Franziska (2017). Capturing the 3′ fragmentome: Transcriptome-wide identification of endogenous NMD targets and analysis of their endonucleolytic decay. Thesis Abstract, Universität zu Köln.

Schwab, Stephanie (2017). Assembly and Regulation of the Yeast 20S Proteasome. Thesis Abstract, Universität zu Köln.

Joseph, Christine (2017). Coagulation-Independent Effects of Factor Xa and Thrombin on Protease-Activated Receptor 1 and 2 in Experimental Pulmonary Hypertension. Thesis Abstract, Universität zu Köln.

Schatton, Desiree (2017). CLUH integrates mitochondrial metabolism and mTOR complex 1 signaling upon starvation. Thesis Abstract, Universität zu Köln.

Al-Maarri, Mona (2017). AKT activation in chronic lymphocytic leukemia cells promotes transformation towards aggressive Richter's syndrome. Thesis Abstract, Universität zu Köln.

Mundorf, Juliane (2017). Ets21c - A Novel Regulator of Epithelial Homeostasis Downstream of JNK. Thesis Abstract, Universität zu Köln.

Finger, Fabian (2017). microRNA-Dependent Regulation of Proteostasis and Longevity. Thesis Abstract, Universität zu Köln.

Becker, Christina (2017). Role of the mitochondrial ATP-dependent Clp protease in mammalian metabolism. PhD thesis, Universität zu Köln.

Zhang, Lei ORCID: 0000-0003-2186-9285 (2017). Identification and Characterization of Genes underlying Natural variation in Flowering Time in Arabidopsis thaliana. PhD thesis, Universität zu Köln.

Lebrun, Astrid, Lo Re, Sandra, Chantry, Mathilde, Carerra, Xavier Izquierdo, Uwambayinema, Francine, Ricci, Doriana, Devosse, Raynal, Ibouraadaten, Saloua, Brombin, Lisa, Palmai-Pallag, Mihaly, Yakoub, Yousof, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Lison, Dominique ORCID: 0000-0001-6557-2518 and Huaux, Francois (2017). CCR2(+) monocytic myeloid-derived suppressor cells (M-MDSCs) inhibit collagen degradation and promote lung fibrosis by producing transforming growth factor-1. J. Pathol., 243 (3). S. 320 - 331. HOBOKEN: WILEY. ISSN 1096-9896

Gerbracht, Jennifer V. ORCID: 0000-0002-3377-4649, Boehm, Volker ORCID: 0000-0001-7588-9842 and Gehring, Niels H. (2017). Plasmid transfection influences the readout of nonsense-mediated mRNA decay reporter assays in human cells. Sci Rep, 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Van, Trieu-My, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Straub, Beate Katharina, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Papadopoulou, Nikoletta and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J. Clin. Invest., 127 (7). S. 2662 - 2678. ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 1558-8238

Saleh, Danish, Najjar, Malek, Zelic, Matija, Shah, Saumil, Nogusa, Shoko, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Paczosa, Michelle K., Gough, Peter J., Bertin, John, Whalen, Michael, Fitzgerald, Katherine A., Slavov, Nikolai ORCID: 0000-0003-2035-1820, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Balachandran, Siddharth, Kelliher, Michelle, Mecsas, Joan and Degterev, Alexei (2017). Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-beta Synthesis Induced by Lipopolysaccharide. J. Immunol., 198 (11). S. 4435 - 4448. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Jaco, Isabel, Annibaldi, Alessandro ORCID: 0000-0002-0346-4340, Lalaoui, Najoua ORCID: 0000-0002-0165-3324, Wilson, Rebecca, Tenev, Tencho, Laurien, Lucie, Kim, Chun ORCID: 0000-0001-9497-708X, Jamal, Kunzah, John, Sidonie Wicky, Liccardi, Gianmaria, Chau, Diep, Murphy, James M., Brumatti, Gabriela, Feltham, Rebecca, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Silke, John ORCID: 0000-0002-7611-5774 and Meier, Pascal ORCID: 0000-0003-2760-6523 (2017). MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death. Mol. Cell, 66 (5). S. 698 - 716. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Kumari, Snehlata, Vlantis, Katerina and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). The interplay of IKK, NF-kappa B and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation. Immunol. Rev., 277 (1). S. 113 - 128. HOBOKEN: WILEY. ISSN 1600-065X

Kumari, Snehlata and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). Epithelial Cell Death and Inflammation in Skin. In: Current Topics in Microbiology and Immunology, S. 77 - 94. BERLIN: SPRINGER-VERLAG BERLIN. ISBN 978-3-319-23913-2; 978-3-319-23912-5

2016

Ackermann, Leena (2016). Ubiquitin-Dependent Regulation of DNA repair and Apoptosis. Thesis Abstract, Universität zu Köln.

Rübsam, Matthias (2016). The role of cadherins in regulation of tension, signaling and barrier formation. Thesis Abstract, Universität zu Köln.

Ralevski, Alexandra (2016). The role of FMT and FIS1A in mitochondrial morphology and salt stress in Arabidopsis thaliana. PhD thesis, Universität zu Köln.

Ali, Noelle Jessebelle Audrina (2016). Role of the polarity protein Par3 in epidermal homeostasis and wound induced regeneration. Thesis Abstract, Universität zu Köln.

Du, Juanjiangmeng (2016). An Integrative Genomic Study of Dupuytren's Disease. PhD thesis, Universität zu Köln.

Aaltonen, Mari (2016). Lipid transfer proteins and membrane contact sites organize lipid synthesis in mitochondria. Thesis Abstract, Universität zu Köln.

Vorholt, Daniela (2016). Functional Implications and Interaction of Macrophages in the Leukemic Microenvironment upon Genotoxic Stress. Thesis Abstract, Universität zu Köln.

Qiu, Jingde (2016). A study of mutual antagonism between EDS1 and transcription factor MYC2 in Arabidopsis immunity. PhD thesis, Max Planck Institute for Plant Breeding Research.

Hegde, Vishal (2016). Regulation of polyamine biosynthesis: Proteolytic control of Ornithine Decarboxylase-Antizyme. Thesis Abstract, Universität zu Köln.

Srivastava, Anchal (2016). Functional analysis of the role of GCN2 kinase in longevity and amino acid homeostasis in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Bustos Parra, Victor Manuel (2016). Functional analysis of the role of FOXO in ageing and metabolism in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Breddermann, Hannes (2016). Transcription control of the pleiotropic regulator and H-NS antagonist LeuO in Escherichia coli. Thesis Abstract, Universität zu Köln.

Lückoff, Anika (2016). Interferon beta signaling and microglial activation in a murine model for age-related macular degeneration. PhD thesis, Universität zu Köln.

Ahmad, Ilyas (2016). Molecular Genetics of Primary Microcephaly and Microcephalic Primordial Dwarfism in Consanguineous Families from Pakistan. PhD thesis, Universität zu Köln.

Mulki, Mohamed Aman (2016). Functional Characterization of Photoperiod Response Genes in Barley. Thesis Abstract, Universität zu Köln.

Pavlenko, Victor (2016). Identification of Genes Modulating Mitochondrial Biogenesis in Caenorhabditis elegans. PhD thesis, Universität zu Köln.

Wang, Shuaiyu (2016). Neurodegeneration and the m-AAA protease: pathogenic cascades in neurons and myelinating cells. PhD thesis, Universität zu Köln.

Biewer, Matthias (2016). Die evolutionäre Dynamik der komplementären Geschlechtsdetermination und Entwicklung von Eusozialität in verschiedenen Hymenopteren. Thesis Abstract, Universität zu Köln.

Jacob, Florence (2016). Cell death and transcriptional signalling mediated by the coiled-coil domain of the barley resistance protein MLA. PhD thesis, Universität zu Köln.

Damm, Anna Maria (2016). Functional characterisation of the NLR protein NLRP10. Thesis Abstract, Universität zu Köln.

Patel, Vipul Kumar (2016). Genotyping by sequencing from sparse sequenced genomes representations from bi- and multi- parental mapping population using a HMM approach. PhD thesis, Universität zu Köln.

Subramanian, Venkatesh Krishna (2016). Characterization of an olfactory receptor mediating aversive behaviour to a death-associated odour. PhD thesis, Universität zu Köln.

Vorhagen, Susanne (2016). aPKCλ function in epidermal spindle orientation, cell fate regulation and skin carcinogenesis. Thesis Abstract, Universität zu Köln.

Gutschmidt, Aljona (2016). Regulation der ER-Homöostase in Caenorhabditis elegans. Thesis Abstract, Universität zu Köln.

Ivandic, Ivan (2016). CRISPR/Cas9 knockout and functional characterization of gnav1. Thesis Abstract, Universität zu Köln.

Averkov, Volodymyr (2016). Tissue-specific roles of Snail-like transcription factors in the embryogenesis of Drosophila melanogaster. PhD thesis, Universität zu Köln.

Nguyen, Phuong-Hien (2016). In vivo Functional Characterization of LYN Kinase in the Pathogenesis of Chronic Lymphocytic Leukemia. Thesis Abstract, Universität zu Köln.

Cepeda Cores, Estela (2016). KLF-1 mediates mitohormesis by orchestrating a xenobiotic detoxification response essential for longevity in C.elegans. PhD thesis, Universität zu Köln.

Knyphausen, Philipp (2016). Post-translational lysine-acetylation of Ran and its regulation by Sirtuin deacetylases. PhD thesis, Universität zu Köln.

Broxtermann, Pia Nora (2016). Ubiquitin ligase activity of XIAP in cellular inflammatory response. Thesis Abstract, Universität zu Köln.

Kuhlmann, Nora (2016). Regulation of RhoGDIα by lysine acetylation and its consequences on Rho signalling. Thesis Abstract, Universität zu Köln.

Hofer, Annette (2016). Role of SIRT3 and GCN5L1 in regulation of biogenesis and structural organization of the respiratory chain through reversible lysine acetylation. Thesis Abstract, Universität zu Köln.

Warner, Kathrin (2016). Proficiency and mechanisms of perturbation of mature T-cell homeostasis by the TCL1 family of oncogenes. PhD thesis, Universität zu Köln.

König, Tim (2016). m-AAA proteases protect against neurodegeneration by regulating mitochondrial protein biogenesis and Ca2+ homeostasis. Thesis Abstract, Universität zu Köln.

Ou, Hui-Ling (2016). DNA Damage Response in Caenorhabditis elegans Germlines. Thesis Abstract, Institut für Genetik, Universität zu Köln.

Eckhoff, Julia (2016). Mechanistic and structural characterization of the SUMO-specific protease Ulp2. PhD thesis, Universität zu Köln.

Stephan, Alexander (2016). The Role of Neutrophil Extracellular Traps in Assisting Macrophage Antimycobacterial Responses. Thesis Abstract, Universität zu Köln.

Fatscher, Tobias (2016). Inhibition of nonsense-mediated mRNA decay by the cytoplasmic poly(A)-binding protein. PhD thesis, Universität zu Köln.

Matic, Stanka (2016). Molecular mechanisms of mitochondrial DNA replication. PhD thesis, Universität zu Köln.

Garmhausen, Marius (2016). A Systems Perspective on the Exit from Pluripotency. Thesis Abstract, Universität zu Köln.

Zaplatina, Alina (2016). The role of VEGFR2 mutants for tumor angiogenesis and metastasis in lung cancer. Thesis Abstract, Universität zu Köln.

2015

Claudius, Ann-Katrin (2015). Cutting through the complex(ity). Characterization of tissue specific effects of the splicing factors Ecdysoneless and Prp8 in Drosophila melanogaster. Thesis Abstract, Universität zu Köln.

Bakka, Kavya (2015). Role of the mitochondrial m-AAA protease in quality control and calcium homeostasis. Thesis Abstract, Universität zu Köln.

Johann, Anna Elisabeth Alice (2015). Towards a molecular understanding of mitochondrial prohibitin function. Thesis Abstract, Universität zu Köln.

Rawat, Vimal (2015). Genome re-annotation and DNA motif identification in Brassicaceae species. PhD thesis, Universität zu Köln.

Gorsky, Marianna Karina (2015). Lysine Acetylation as a Modulator of Human Tau-Induced Toxicity in Vivo. Thesis Abstract, Universität zu Köln.

Maiti, Priyanka (2015). The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD thesis, Universität zu Köln.

Kawalia, Amit (2015). Addressing NGS Data Challenges: Efficient High Throughput Processing and Sequencing Error Detection. PhD thesis, Universität zu Köln.

Di Domenico, Antonella (2015). The role of mitochondrial acetylation state in the regulation of oxidative phosphorylation. Thesis Abstract, Universität zu Köln.

Dannappel, Marius Volker (2015). In vivo role of RIPK1 in the regulation of the murine intestinal epithelium. PhD thesis, Universität zu Köln.

Donohoe, Colin (2015). Atf3 Bridges the Gap Between Cell Polarity and the Nucleus. Thesis Abstract, Universität zu Köln.

Afschar, Sonita (2015). The Hormone Nuclear Receptor DHR96 and its role in Ageing. PhD thesis, Max Planck Institute for Biology of Ageing.

Akyuz, Melek Emine (2015). Role of the chaperone-assisted E3 ligase CHN-1/CHIP in lifespan regulation and stress response. Thesis Abstract, Universität zu Köln.

Akyüz, Mehmet Deniz (2015). IGF-1R dependent stress responses in epidermal homeostasis and regeneration. Thesis Abstract, Universität zu Köln.

Ghatak, Sushmita (2015). Characterization of the extracellular matrix niche and stem cell homeostasis during skin aging. Thesis Abstract, Universität zu Köln.

Kantzer, Christina Geraldine (2015). Astrocyte cell surface marker phenotyping: Identification of multipotent ACSA-2-/GLAST+ cerebellar progenitor cells. PhD thesis, Universität zu Köln.

García Márquez, María Alejandra (2015). Characterization of four functionally distinct human B-cell subsets that are defined by the expression of CD21 and CD86. PhD thesis, Universität zu Köln.

Wachsmuth, Laurens (2015). Role of NF-κB mediated transcriptional regulation of Nfkbia/IκBα expression in vitro and in vivo. Thesis Abstract, Universität zu Köln.

Denson, Jesse Lee (2015). Central Interleukin-6 Signaling Regulates Food Intake and Peripheral Glucose Homeostasis. Thesis Abstract, Universität zu Köln.

Müller, Urs Benedikt (2015). Polymorphism in the IRG resistance system determines virulence of Toxoplasma gondii in mice. Thesis Abstract, Universität zu Köln.

Sauer, Maike (2015). Natural killer cell-mediated tumor immunosurveillance: Molecular mechanisms directing the expression of ligands for NKG2D. Thesis Abstract, Universität zu Köln.

Beenukumar Renukadevi, Roshini (2015). Ubiquitin-Independent Proteolytic Targeting of Ornithine Decarboxylase. PhD thesis, Universität zu Köln.

Gao, Jie (2015). Elucidating the molecular function of CLUH in mammalian system. PhD thesis, Universität zu Köln.

Ruppert, Ann-Kathrin (2015). Integrative functional genomic search for regulatory DNA sequence polymorphisms influencing DNA methylation and mRNA expression in hippocampal brain tissue. PhD thesis, Universität zu Köln.

Ackermann, Philipp Justus (2015). Characterization of inflammatory signaling in the tumor microenvironment using SOCS3-U mice. PhD thesis, Universität zu Köln.

Reth, Marcel von (2015). Functional analysis of STRUBBELIG RECEPTOR FAMILY 3: a Receptor-like Kinase involved in Hybrid Incompatibility in Arabidopsis thaliana. Thesis Abstract, Universität zu Köln.

Pannes, Andrea (2015). Novel Functional and Genetic Findings in Autosomal Dominant Tubulointerstitial Kidney Disease. Thesis Abstract, Universität zu Köln.

Ricardo de Oliveira Nunes, Maria Manuel (2015). Characterization of proteasome precursor complexes. Thesis Abstract, Universität zu Köln.

Saedler, Katarzyna (2015). Role of peripheral tissue FTO in energy homeostasis and in chemically-induced hepatocarcinogenesis. Thesis Abstract, Universität zu Köln.

Wennhold, Kerstin (2015). Tumorantigen-Specific CD40B Cells: Combining Enhanced Antigen-Presentation and Antibody-Secretion for Tumor Targeting. PhD thesis, Universität zu Köln.

Plenker, Dennis (2015). Functional analysis of CD74-NRG1 - a new recurrent oncogenic gene fusion in lung adenocarcinoma. PhD thesis, Universität zu Köln.

Heesen, Ludwig (2015). Analyses of spinal muscular atrophy (SMA) modifiers and drug-dependent responses using motoneurons (MNs) derived from induced pluripotent stem cells (iPSCs). PhD thesis, Universität zu Köln.

Barthel, Romy (2015). Function of the CD74 receptor in B cell pro-survival signaling in the context of chronic lymphocytic leukemia. PhD thesis, Universität zu Köln.

Boor, Susanne de (2015). Mechanistic studies on the regulation of Ran-function by post-translational lysine-acetylation. PhD thesis, Universität zu Köln.

Gröne, Kerstin (2015). Proteolytic regulation of mitochondrial phospholipid metabolism by the i-AAA protease Yme1. Thesis Abstract, Universität zu Köln.

Böhm, Volker (2015). Surveillance of mRNP composition during translation termination regulates gene expression via nonsense-mediated mRNA decay. PhD thesis, Universität zu Köln.

Stephan, Johannes (2015). Understanding complex traits by non-linear mixed models. PhD thesis, Universität zu Köln.

Pannen, Hans Derk (2015). Analysis of transcriptional regulation by RcsB homo- and heterodimers in Escherichia coli. PhD thesis, Universität zu Köln.

Wroblowski, Sarah Christine (2015). Einfluss posttranslationaler N-ε-Lysin Acetylierung auf die RhoGDIα Funktion. Thesis Abstract, Universität zu Köln.

Brenig, Julian (2015). Structural and mechanistic studies of the inhibitory effect of Liprin-alpha3 on mDia1 function. PhD thesis, Universität zu Köln.

Seiferling, Dominic (2015). Regulation of the mammalian mitochondrial unfolded protein response. PhD thesis, Universität zu Köln.

2014

Gromadzka, Agnieszka Marta (2014). Identification of determinants for export factors binding to spliced mRNAs. PhD thesis, Universität zu Köln.

Tsaousidou, Eva (2014). Hypothalamic Inflammation in Obesity, Insulin Resistance and Ageing. PhD thesis, Universität zu Köln.

Syed, Adnan Shahzad (2014). Integrative analysis of branch points in the evolution of chemosensory receptor repertories: unexpected properties of amphibian olfactory and coelacanth taste receptors. PhD thesis, Universität zu Köln.

Gaurav, Ahuja (2014). Molecular characterization of known and novel olfactory subsystems in the zebrafish. PhD thesis, Universität zu Köln.

Maric-Biresev, Jelena (2014). GMS proteins shield endocellular membranes from accumulation of effector Immunity-Related GTPases. PhD thesis, Universität zu Köln.

Meyer-Teschendorf, Katrin (2014). Substrate-recognition of SUMO-targeted ubiquitin ligases by specific SUMO-SIM interactions. Thesis Abstract, Universität zu Köln.

Ciriello, Simona (2014). Separate functions of BTZ during post-­transcriptional gene regulation. PhD thesis, Universität zu Köln.

Krause, Anke (2014). Posttranslationale Modifikation des Proteins der Promyelozytenleukämie (PML) nach unterschiedlicher Stressinduktion. PhD thesis, Universität zu Köln.

Ikram, Hafiza Fakhera (2014). Identification and Characterization of Genetic Alterations in Neuroblastoma and their Prognostic Relevance. Thesis Abstract, Universität zu Köln.

Dumitru, Iulia (2014). Characterization of mammalian mitochondrial factors EF-G1 and Mto1. Thesis Abstract, Universität zu Köln.

Muktar, Meki Shehabu (2014). Using comparative transcript profiling and association mapping to detect QTLs and diagnostic SNP markers for maturity corrected resistance to Phytophthora infestans in potato (Solanum tuberosum L.). PhD thesis, Universität zu Köln.

Subramanian, Senthil Kumar (2014). Differential Influence of Clinical Mycobacterium avium Strains on Distinct Autonomous Defense Capacities of Human Neutrophils. PhD thesis, Universität zu Köln.

Springer-Frauenhoff, Helen Maria (2014). The immunity-related GTPase (IRG) resistance system against intracellular parasites. PhD thesis, Universität zu Köln.

Kondadi, Arun Kumar (2014). AFG3L2 deficiency impairs axonal transport of mitochondria dependent on ROS and tau levels. PhD thesis, Universität zu Köln.

Steckelberg, Anna-Lena (2014). CWC22 Supports Pre-mRNA Splicing and Exon Junction Complex Assembly. PhD thesis, Universität zu Köln.

Vogt, Benjamin (2014). A bioinformatical approach for a reliable determination of short motifs for SUMO and Atg8 interaction in Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Hansen, Henriette Elena (2014). A conditional mouse model to elucidate the role of the CLUH protein in vivo. Thesis Abstract, Universität zu Köln.

Velikkakam James, Geo (2014). Method development and application of Next Generation Sequencing in forward genetics. PhD thesis, Universität zu Köln.

Storm, Nadia Jin and Denzel, Martin S. (2014). Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life. Cell (156). pp. 1167-1178. Elsevier.

Günschmann, Christian (2014). Role of Insulin/IGF-1-regulated FoxO transcription factors in epidermal morphogenesis. PhD thesis, Universität zu Köln.

Sriramachandran, Annie Miriam (2014). Substrate specificity and regulation of SUMO-targeted ubiquitin ligases in yeast and in humans. Thesis Abstract, Universität zu Köln.

Wolters, Stefanie (2014). Molecular characterization of the UV-response in Caenorhabditis elegans. PhD thesis, Universität zu Köln.

Vogt, Merly Carlotta (2014). Metabolic Programming of Hypothalamic Neurocircuits by Maternal High-Fat Feeding. PhD thesis, Universität zu Köln.

Förster, Anja (2014). The role of pro- and anti-apoptotic proteins for homeostasis and function of mast cells. Thesis Abstract, Universität zu Köln.

Almajan, Eva-Ruxandra (2014). Neuronal and astroglial autonomous role of AFG3L2 in neurodegeneration. Thesis Abstract, Universität zu Köln.

Schüll, Stephan (2014). The Molecular Mechanisms Underlying the Cytochrome C Oxidase Dysfunction-Induced Accelerated Apoptosis. PhD thesis, Universität zu Köln.

Kandasamy, Ganapathi (2014). Role of molecular chaperones in ubiquitin-dependent protein degradation. Thesis Abstract, Institute for Genetics.

Ising, Christina (2014). The role of prohibitin-2 in podocytes – mitochondrial function and beyond. PhD thesis, Universität zu Köln.

Schell, Michael (2014). The role of the Caenorhabditis elegans E4 enzyme UFD-2 in DNA damage repair and apoptosis. Thesis Abstract, Universität zu Köln.

Korwitz, Anne (2014). Dissecting the roles of L-OPA1 and prohibitins in neuronal survival. Thesis Abstract, Universität zu Köln.

Tröder, Simon Erwin (2014). A protective function against apoptosis revealed by the neuronal interactome of the mitochondrial m-AAA protease. Thesis Abstract, Universität zu Köln.

Noe, Natalie Isabelle (2014). Role of PGC-1α and PGC-1β in inflammatory processes. Thesis Abstract, Universität zu Köln.

Pirson, Paul Ansgar (2014). Regulation of DNA replication by CDC-48 cofactors. Thesis Abstract, Universität zu Köln.

Blissenbach, Birgit (2014). The role of canonical microRNA-biogenesis pathway in macrophages and mast cells upon infection. Thesis Abstract, Universität zu Köln.

2013

Berghausen, Eva Maria (2013). The role of the PI 3-Kinase isoform p110alpha for vascular remodeling in experimental pulmonary hypertension. Thesis Abstract, Universität zu Köln.

Müller, Sebastian (2013). Functional analysis of the mammalian rhomboid protease PARL. Thesis Abstract, Universität zu Köln.

Wenkel, Simone (2013). Die Molekularbiologie in Deutschland von 1945 bis 1975 - Ein internationaler Vergleich. PhD thesis, Universität zu Köln.

Heß, Martin (2013). The fat mass and obesity-associated protein (Fto) regulates activity of the dopaminergic circuitry. PhD thesis, Universität zu Köln.

Dogan, Sükrü Anil (2013). Mitochondrial Aspartyl-tRNA Synthetase (DARS2) Deficiency and Tissue-Specific Consequences of Defective Mitochondrial Translation. PhD thesis, Universität zu Köln.

Lal, Dennis (2013). Rare genetic risk factors in common idiopathic epilepsy syndromes. PhD thesis, Universität zu Köln.

Seidel, Danila (2013). Epidemiological and functional characterization of oncogenic drivers in lung cancer. PhD thesis, Universität zu Köln.

Preukschat, Daniela (2013). Function of constitutive IκB Kinase 2 activation in the epidermis of mice. Thesis Abstract, Universität zu Köln.

Porri, Aimone (2013). Tissue specific action of Gibberellin in Arabidopsis flowering and development. PhD thesis, Universität zu Köln.

Gruber, Sabine (2013). The Role of Interleukin 6 and Obesity in the Development of Hepatocellular Carcinoma. PhD thesis, Universität zu Köln.

Zapilko, Veronika (2013). Identifizierung Ergothionein-haltiger Zellen im Zebrabärbling Danio rerio. PhD thesis, Universität zu Köln.

Haile, Ermias Habte (2013). The Effect of Natural Variation at Ppd-H1 and HvELF3 on Responses to Osmotic Stress in Barley (Hordeum Vulgare). PhD thesis, Universität zu Köln.

Dreck, Katrin (2013). Functional characterization of the transcription factor YjjQ in Escherichia coli. PhD thesis, Universität zu Köln.

Trucks, Holger Sebastian (2013). Association mapping of genomic microdeletions and common susceptibility variants predisposing to genetic generalized epilepsies. PhD thesis, Universität zu Köln.

Rott, Matthias (2013). Structure and assembly cues of Arabidopsis root-inhabiting bacterial communities and comparative genomics of selected Rhizobium members. PhD thesis, Universität zu Köln.

Andree, Maria (2013). XIAP Confers Immunity Against Intracellular Bacteria. PhD thesis, Universität zu Köln.

Weber, Stefanie (2013). Fremde DNA im menschlichen Genom: Konsequenzen für das Wirts- und das Fremdgenom. PhD thesis, Universität zu Köln.

Kümmler, Nils Christian (2013). Activating transcription factor 3 and its role in haematopoiesis and innate immunity in Drosophila melanogaster. Thesis Abstract, Universität zu Köln.

Külshammer, Eva (2013). The actin cross-linker Filamin A/Cheerio mediates tumor malignancy downstream of JNK signaling. Thesis Abstract, Universität zu Köln.

Schulz, Alexandra (2013). Impact of B cell receptor activation and epigenetic regulation on TOSO - a novel NF-κB and BCL6 target gene in Chronic Lymphocytic Leukemia. Thesis Abstract, Universität zu Köln.

Fleckenstein, Martin Christian (2013). The Toxoplasma gondii pseudokinase ROP5 is crucial for inactivation of the murine IRG resistance system. Thesis Abstract, Universität zu Köln.

Niessen, Michaela Tosca (2013). Role of aPKCl in epidermal morphogenesis and homeostasis. PhD thesis, Universität zu Köln.

Koch, Kristina (2013). The role of Nuclear Factor κB in the cellular response to different radiation qualities. PhD thesis, Universität zu Köln.

Knipper, Johanna (2013). Mechanisms and functional consequences of macrophage activation in skin repair. Thesis Abstract, Universität zu Köln.

Neuhaus, Johannes (2013). Generation and expansion of mitochondrial DNA deletions in dopaminergic neurons: new evidences for a direct role of dopamine metabolism. Thesis Abstract, Universität zu Köln.

Neerincx, Andreas Heinrich (2013). Characterization of the human NLR protein NLRC5. PhD thesis, Universität zu Köln.

Gerdes, Florian (2013). Comprehensive analysis of the m-AAA protease interactome in Saccharomyces cerevisiae. Thesis Abstract, Universität zu Köln.

2012

Willmes, Diana Maria (2012). The role of Ceramide Synthase 6 (CerS6) in obesity. Thesis Abstract, Universität zu Köln.

Willenborg, Sebastian (2012). Molecular mechanisms controlling sensors and effectors in skin damage and repair. Thesis Abstract, Universität zu Köln.

Agarwal, Pallavi (2012). Role of COMP in skin connective tissue architecture and fibrotic diseases. Thesis Abstract, Universität zu Köln.

Ngum, Anna Abety (2012). Role of host-derived ADAM-9 in tumor invasion and metastasis of malignant melanoma. PhD thesis, Universität zu Köln.

Weßling, Ralf (2012). Isolation and functional characterization of Arabidopsis powdery mildew effector proteins. PhD thesis, Universität zu Köln.

Li, Jingtao (2012). Haplotypic polymorphism of the IRG protein family mediates resistance of mice against virulent strains of Toxoplasma gondii. Thesis Abstract, Universität zu Köln.

Rollins, Jarod (2012). Genetic and Proteomic Responses to Abiotic Stress in Barley (Hordeum vulgare). PhD thesis, Universität zu Köln.

Wollstein, Andreas (2012). Genetic Analysis of Human Evolution: The Case of Oceania. Thesis Abstract, Universität zu Köln.

Böcke, Alexandra (2012). FAN mediates navigational capacity in leukocytes and tumour cells. PhD thesis, Universität zu Köln.

Stratmann, Thomas (2012). Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli. PhD thesis, Universität zu Köln.

Schönefuß, Alexander (2012). Role of melanoma-derived ADAM-9 for invasion and metastasis of melanoma. PhD thesis, Universität zu Köln.

Schön, Moritz (2012). The role of Arabidopsis transcription factors WRKY18 and WRKY40 in plant immunity. PhD thesis, Universität zu Köln.

Leu, Costin (2012). Molekulargenetische Exploration der idiopathisch generalisierten Epilepsien. PhD thesis, Universität zu Köln.

Welz, Patrick-Simon (2012). In vivo analysis of the role of FADD in the regulation of intestinal epithelial homeostasis. PhD thesis, Universität zu Köln.

Noetel, Andrea (2012). Bedeutung neuronaler microRNAs während der myofibroblastischen Transdifferenzierung hepatischer Sternzellen. PhD thesis, Universität zu Köln.

Keßler, Jörg (2012). NK cells in tumor immune evasion: Role of tumor-associated ligands that regulate NK cell function and therapeutical implications. PhD thesis, Universität zu Köln.

Brinkmann, Kerstin (2012). Ubiquitin C-terminal hydrolase-L1 (UCH-L1) stabilizes NOXA and impacts on cancer chemosusceptibility. PhD thesis, Universität zu Köln.

Schütte, Fabian (2012). Characterization of insulin receptor and insulin like growth factor 1 receptor deficient mice. PhD thesis, Universität zu Köln.

Moll, Lorna (2012). The role of FoxO1 in neurodegenerative diseases. PhD thesis, Universität zu Köln.

Hartwig, Benjamin (2012). ALP1 and ELP1 – novel genetic modifiers of LIKE HETEROCHROMATIN PROTEIN 1 participate in Polycomb mediated gene repression in Arabidopsis. PhD thesis, Universität zu Köln.

Potting, Christoph (2012). The regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. Thesis Abstract, Universität zu Köln.

Pal, Martin (2012). Stress Signaling Pathways in Metabolic Disorders. PhD thesis, Universität zu Köln.

Bielig, Harald Frank (2012). Screening for components involved in NLR-mediated immune signalling. PhD thesis, Universität zu Köln.

Ströhle, Peter Dirk (2012). The role of inflammatory mediators in the development of insulin resistance and hepatocellular carcinoma. PhD thesis, Universität zu Köln.

Kwasny, Thomas Franz (2012). Die Rolle der nSMase3 in der Regulation des postnatalen Wachstums der Maus. PhD thesis, Universität zu Köln.

Franz, André (2012). Role of the ubiquitin-selective CDC-48/UFD-1/NPL-4 chaperone in DNA replication. PhD thesis, Universität zu Köln.

Bieling, Angela Maria (2012). Zelluläre Antwort auf mitochondrialen Stress infolge einer Nonsense-Mutation in der Cytochrom-c-Oxidase Untereinheit 1 (COX1) in humanen Cybridzellen. Thesis Abstract, Universität zu Köln.

Anton, Fabian (2012). Regulation of Mitochondrial Outer Membrane Fusion by the Mitofusin Fzo1. Thesis Abstract, Universität zu Köln.

Becker, Kerstin (2012). Molecular Genetics of Dupuytren´s Disease. PhD thesis, Universität zu Köln.

2011

Vlantis, Katerina (2011). Function of constitutive IκB Kinase 2 activation in the intestinal epithelium of mice. PhD thesis, Universität zu Köln.

Zielinski, Julia (2011). Analysis of fish-specific NLRs in zebrafish, Danio rerio. PhD thesis, Universität zu Köln.

Tintor, Nico (2011). Genetic analysis of MAMP-triggered immunity in Arabidopsis. PhD thesis, Universität zu Köln.

Zurek, Birte Helene (2011). TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation. PhD thesis, Universität zu Köln.

Naumann, Anja Barbara (2011). Epigenetische und funktionelle Charakterisierung der 5'-upstream Region des menschlichen FMR1 Gens. PhD thesis, Universität zu Köln.

Lu, Xunli (2011). Genetic Analysis of Plant Innate Immunity. Thesis Abstract, Universität zu Köln.

Ackermann, Bastian (2011). Analysis of the modifying influence of Plastin 3 (PLS3) on Spinal Muscular Atrophy (SMA) by generation of transgenic mouse models. PhD thesis, Universität zu Köln.

Tim, Klöckener (2011). Insulin regulates Energy Homeostasis and Hypoglycemia in the Ventromedial Hypothalamus. PhD thesis, Universität zu Köln.

Kavalchuk, Kanstantsin (2011). Osmoregulation of the proU operon at a post-transcriptional level in Escherichia coli. PhD thesis, Universität zu Köln.

Grotha, Stefan Philipp (2011). Identification of novel therapeutic targets in mastocytosis: Inhibition of survival of neoplastic mast cells by targeting IAPs and TRAIL receptors. PhD thesis, Universität zu Köln.

Chung, Yoon-Suk Alexander (2011). Characterization of Phagocytic Pattern Recognition Receptors in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Kakanj, Parisa (2011). Indian hedgehog function in skin development and tumour formation. PhD thesis, Universität zu Köln.

Jakubik, Miriam (2011). Generierung und Charakterisierung von konditionalen Bdp1-knockout-Mausmodellen - Analysen des Transkriptionsfaktor IIIB-Komplexes. PhD thesis, Universität zu Köln.

Hahn, Olga (2011). Generierung einer Maus mit Antigen Rezeptor transgenen T-Zellen. PhD thesis, Universität zu Köln.

Herrero Serrano, Eva (2011). A molecular basis of ELF3 action in the Arabidopsis circadian clock. PhD thesis, Universität zu Köln.

Kwiecinski, Monika (2011). Die Rolle der microRNA-29 während der Leberfibrogenese. PhD thesis, Universität zu Köln.

Hussain, Muhammad Sajid (2011). Molecular Genetic Analysis of Autosomal Recessive Primary Microcephaly in Pakistani Kindreds. PhD thesis, Universität zu Köln.

Ukken, Fiona Paul (2011). Functional characterisation of the Sterile 20 like kinase Slik in tracheal morphogenesis in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Reiss, Martina (2011). Characterization of Sirt2 using conditional RNAi in mice. PhD thesis, Universität zu Köln.

Stein, Cornelia (2011). Innate immune genes in the zebrafish, Danio rerio. PhD thesis, Universität zu Köln.

Kuschewski, Ruth (2011). Gp130 Signaling In POMC Neurons Is Required For CNTF-Induced Anorexia. PhD thesis, Universität zu Köln.

Kuhn, Jennifer (2011). Molecular Genetics of Alopecia Areata in Dundee Experimental Bald Rats and in Humans. PhD thesis, Universität zu Köln.

Niemann, Rabea (2011). Untersuchungen zur Rolle von Transkripten unbekannter Funktion für die Kardiomyogenese und Funktion von Kardiomyozyten im Zebrafisch (Danio rerio) und in murinen embryonalen Stammzellen. PhD thesis, Universität zu Köln.

Bechtel, Manuela Christina (2011). Identifizierung von in vivo Bindungspartnern der Basalmembranproteine Nidogen-1 und Nidogen-2. Thesis Abstract, Universität zu Köln.

Löwe, Thomas (2011). Dimerisierung der Ubiquitinligase CHN-1 im Kontext der Regulation des Myosinchaperons UNC-45. Thesis Abstract, Universität zu Köln.

Seufert, Sebastian Marcus (2011). Inhibition der Glioblastom-vermittelten Sekretion von Glutamat und pro-migratorischem TGF-ß: Untersuchung der anti-Tumoraktivität in vitro, ex vivo und in vivo. Thesis Abstract, Universität zu Köln.

Klisch, Bruno (2011). The role of skeletal muscle IL-6Ra signalling in glucose homeostasis. Thesis Abstract, Universität zu Köln.

Wegner, Nina Vanessa (2011). Identification of in vivo interactions of insulin receptor substrate 1 in murine liver. PhD thesis, Universität zu Köln.

Ameln, Simon von (2011). Eine hypofunktionelle Mutation in der Polynukleotid-Phosphorylase führt zu einer autosomal-rezessiven nicht-syndromalen Hörstörung. PhD thesis, Universität zu Köln.

Spallek, Thomas (2011). New insights into the FLS2 trafficking and signaling pathway revealing a role for late defense responses in Arabidopsis immunity. PhD thesis, Universität zu Köln.

Riese, Anna (2011). Funktionelle Analyse von Neuropilin 1 und 2 in der Epidermis: Bedeutung in der Wundheilung und in der UVB-induzierten Apoptose. Thesis Abstract, Universität zu Köln.

Kumari, Snehlata (2011). Functions of NF-kappaB pathway in cutaneous inflammation. Thesis Abstract, Universität zu Köln.

2010

Stachelscheid, Heike (2010). Role of IGF-1R/IR signaling in epidermal development and morphogenesis. PhD thesis, Universität zu Köln.

Rühl, Mark (2010). Molecular genetic analysis of the role of GIGANTEA in flower initiation. Thesis Abstract, Universität zu Köln.

Keusekotten, Kirstin (2010). Targeting SUMO conjugates for degradation: The human RING finger RNF4 as a specialized ubiquitin ligase. PhD thesis, Universität zu Köln.

Redemann, Nora (2010). The role of FOXO1 and KATP channel signalling in Sim1 expressing neurons for the regulation of energy homeostasis and stress response. PhD thesis, Universität zu Köln.

Hemmers, Saskia (2010). Novel Roles for Arginine Modifying Enzymes in Immune Regulation. PhD thesis, Universität zu Köln.

Ernst, Marianne Bettina (2010). Transcriptional Regulation of Energy Homeostasis and Metabolism in the Central Nervous System. PhD thesis, Universität zu Köln.

Ganesan, Raja Venkatesh (2010). Analysis of the interaction of the LuxR-type transcription factors BglJ and RcsB and antagonism of H-NS mediated silencing in Escherichia coli. PhD thesis, Universität zu Köln.

Gyetvai, Gábor Miklos (2010). Structural and functional characterization of R1-homologous genes. PhD thesis, Universität zu Köln.

Gödderz, Daniela (2010). Antizyme-mediated targeting of Ornithine Decarboxylase to the proteasome. Thesis Abstract, Universität zu Köln.

Jäckel, Sandra (2010). Identifizierung eines Interaktionspartners von Lethal (2) giant discs (Lgd) in Drosophila melanogaster und konditionale Inaktivierung der lgd-Orthologen in der Maus. PhD thesis, Universität zu Köln.

Heinrichsdorff, Jan (2010). The role of liver p38alpha in acute and chronic inflammatory reactions. PhD thesis, Universität zu Köln.

Bonn, Florian (2010). Examining the proteolytic function of the m-AAA protease in yeast and human. Thesis Abstract, Universität zu Köln.

Gehrke, Iris (2010). Role of the vascular endothelial growth factor (VEGF) in chronic lymphocytic leukemia (CLL): Implications to overcome the apoptotic block. PhD thesis, Universität zu Köln.

Khaminets, Aliaksandr (2010). Mechanisms of Cell-autonomous Resistance to Toxoplasma gondii in Mouse and Man. PhD thesis, Universität zu Köln.

Topolar, Daniela (2010). Der Transport des HLA-B assoziierten Transkript 3 und sein Einfluss auf die NK Zell-Funktion. PhD thesis, Universität zu Köln.

Wilmes, Claudia (2010). Atp23 and Mdm35 perform antagonistic functions in mitochondrial phospholipid metabolism. Thesis Abstract, Universität zu Köln.

Richardson, Dale Newton (2010). Genome duplication and alternative splicing: Gateways to functional diversity. PhD thesis, Universität zu Köln.

Hussain, Ashiq (2010). The teleost taar family of olfactory receptors: From rapidly evolving receptor genes to ligand-induced behavior. PhD thesis, Universität zu Köln.

Riët, Tobias (2010). Erhöhung der Antigen-Selektivität von T-Zellen durch Koexpression chimärer Antigen-Rezeptoren unterschiedlicher Spezifität. PhD thesis, Universität zu Köln.

Belgardt, Bengt-Frederik (2010). Obesity-linked dysfunction of hypothalamic and pituitary circuits in regulation of energy homeostasis. PhD thesis, Universität zu Köln.

Schnellhardt, Marion (2010). Characterization of noncovalent interactions of proteins with the small ubiquitin-like modifier SUMO. Thesis Abstract, Universität zu Köln.

Garbes, Lutz (2010). Histone deacetylase inhibitors for the epigenetic therapy of proximal spinal muscular atrophy. PhD thesis, Universität zu Köln.

Fres, Julia (2010). Post-translational lipid modification and membrane targeting of the dynamin-related large GTPase hGBP1. Thesis Abstract, Universität zu Köln.

Dargazanli, Sascha (2010). Role of Mammalian Prohibitins in the Regulation of Apoptosis. Thesis Abstract, Universität zu Köln.

2009

Hajheidari, Mohsen (2009). Functional analysis of CDKF;1: a plant specific CAK-activating kinase. PhD thesis, Universität zu Köln.

Schmidt, Andreas (2009). Nonsense Mediated Decay Associated Pioneer Round of Translation as Source for Peptides for Presentation by MHC Class I. PhD thesis, Universität zu Köln.

Seeger, Jens Michael (2009). SMAC dependency of XIAP mediated chemoresistance. PhD thesis, Universität zu Köln.

Scholten, Julia (2009). Novel tools for mast cell research: Mast cell-specific Cre-mediated gene inactivation and inducible ablation of mast cells in vivo. PhD thesis, Universität zu Köln.

Holleben, Max v. (2009). Functional Characterisation of SLy2 as a novel regulator of the actin cytoskeleton. PhD thesis, Universität zu Köln.

Reinart, Nina (2009). The Role of Macrophage Migration Inhibitory Factor (MIF) in the Pathogenesis of murine Chronic Lymphocytic Leukemia (CLL) - Analysis based on the TCL1 mouse model. PhD thesis, Universität zu Köln.

Jöcker, Anika (2009). Automatic and manual functional annotation in a distributed web service environment. PhD thesis, Universität zu Köln.

Vijaya Lakshmi, Simhadri (2009). The Role of Tumor Necrosis Factor Receptor Super-Family Member CD30 and its Cognate Ligand CD30L for the Interplay of Immune Effector Cells. PhD thesis, Universität zu Köln.

Friedrichs, Björn (2009). Das Protein URIM bildet in der M-Phase des Zellzyklus einen Komplex mit HIRA und den Histonen H2B, H3 und H4. PhD thesis, Universität zu Köln.

Osman, Christof (2009). Characterization of the genetic interactome of prohibitins in S. cerevisiae. PhD thesis, Universität zu Köln.

Bayer, Till (2009). Duplicated genes and their relevance in the process of speciation. PhD thesis, Universität zu Köln.

Pawlowski, Nikolaus (2009). Complex Formation and the GTP Hydrolysis Mechanism of the Immunity-Related GTPase Irga6. PhD thesis, Universität zu Köln.

Staubach, Fabian (2009). Evolution der Genexpression am Beispiel zweier Subspezies der Hausmaus und populationsgenetische Analyse eines jungen Gens. PhD thesis, Universität zu Köln.

Ederer, Claudia (2009). CCR7 negative T-Zellen benötigen CD28-OX40 Kostimulation für die Immunrezeptor-vermittelte Tumorlyse. PhD thesis, Universität zu Köln.

Märsch, Stephan (2009). Combinatorial engineering of adeno associated virus vectors. PhD thesis, Universität zu Köln.

Hettich, Moritz M. (2009). Role of neuronal IGF-1R signaling for the pathogenesis of Alzheimer's disease. PhD thesis, Universität zu Köln.

Adeyemo, Sarah (2009). Molecular Genetic Characterization of Photoperiodic genes in Cassava (Manihot esculenta Crantz) and attempts to manipulate their expression to promote floral induction. PhD thesis, Universität zu Köln.

Chung, Boidinh (2009). Molekulargenetische und funktionelle Analysen des LRP5-Gens bei einem Osteoporosis-Pseudoglioma-Syndrom-ähnlichen Phänotyp. PhD thesis, Universität zu Köln.

Patz, Michaela (2009). Beteiligung des Transmembranrezeptors CD5 und der durch miRNA modulierten Expression des Proto-Onkogens PLAG1 an der Pathogenese der Chronischen Lymphatischen Leukämie. PhD thesis, Universität zu Köln.

Sabel, Katja (2009). Molekulare Mechanismen der Staphylococcus aureus induzierten Autophagie. PhD thesis, Universität zu Köln.

Baschuk, Nikola (2009). Immune Surveillance of Cancer - Molecular and Translational Aspects of Cytotoxic Effector : Target Cell Interactions. PhD thesis, Universität zu Köln.

Kurian, Leo (2009). Mechanisms regulating ribosomal frameshifting in decoding Ornithine Decarboxylase Antizyme mRNA. Thesis Abstract, Universität zu Köln.

Chaurasia, BhagIrath (2009). Role of myeloid cells specific PDK-1 in inflammation and obesity induced insulin resistance. PhD thesis, Universität zu Köln.

Engmann, Tanja (2009). Structural, physical and genetic interactions of the i-AAA protease Yme1 in Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Raschke, Ines (2009). Mammalian m-AAA Proteases as Key Regulators of Mitochondrial Function - Analysis of Dominant Negative Mutant Variants. PhD thesis, Universität zu Köln.

Hauke, Jan Henning (2009). Molekulare Analyse der epigenetischen Regulation der SMN2-Genaktivität in der Pathogenese der spinalen Muskelatrophie (SMA). PhD thesis, Universität zu Köln.

Rießland, Markus (2009). In vitro and in vivo characterization of histone deacetylase inhibitors as potential therapeutics for autosomal recessive proximal spinal muscular atrophy (SMA). PhD thesis, Universität zu Köln.

Stiller, Barbara (2009). Charakterisierung der P-Typ ATPase Ypk9 in Saccharomyces cerevisiae als Modell für die ATP13A2-bedingte Form der Neurodegeneration. PhD thesis, Universität zu Köln.

Heimbach, André (2009). Identifizierung und Charakterisierung von ATP13A2-Varianten und ihre Bedeutung für neurodegenerative Erkrankungen. PhD thesis, Universität zu Köln.

Bilkovski, Roman (2009). Die Rolle des wnt-5a in der Determinierung humaner mesenchymaler Stammzellen zu Preadipozyten. PhD thesis, Universität zu Köln.

Könner, Anne Christine (2009). Genetic Microdissection of Insulin Action on Neurocircuits in Control of Glucose and Energy Homeostasis. PhD thesis, Universität zu Köln.

Jordan, Sabine (2009). Obesity-induced increase in hepatic expression of microRNA miR-143 impairs glucose homeostasis. Thesis Abstract, Universität zu Köln.

Scavetta, Rick J. (2009). Genomic destabilization at Copy Number Variable Loci in Intersubspecific Hybrids of Mus musculus ssps. Thesis Abstract, Universität zu Köln.

Kwantes, Michiel (2009). Conservation and diversification of MIKC* MADS-domain transcription factors during the evolution of vascular land plants. PhD thesis, Universität zu Köln.

Raatz, Bodo (2009). Characterization of the LATERAL SUPPRESSOR Promoter and the New Regulator of Axillary Meristem Formation ENHANCER OF LATERAL SUPPRESSOR 5. PhD thesis, Universität zu Köln.

Shabanova, Ekaterina (2009). Patterns of genetic recombination and variation in the human genome. PhD thesis, Universität zu Köln.

2008

Saghafi, Sam (2008). Bifunctional Roles for Two Topological Isoforms of the Cellular Prion Protein. PhD thesis, Universität zu Köln.

Thirupathy, Sabari Sankar (2008). The evolution of silent beta-glucoside systems in Escherichia coli. PhD thesis, Universität zu Köln.

Querings, Silvia (2008). Analysis of Rca1 function at the G1-S transition in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Rohmann, Edyta (2008). Identification of the molecular basis of the lacrimo-auriculo-dento-digital (LADD) syndrome. PhD thesis, Universität zu Köln.

Steingen, Caroline (2008). Characterization of key mechanisms involved in transmigration and invasion of mesenchymal stem cells. PhD thesis, Universität zu Köln.

Mesaros, Andrea (2008). Activation of Stat3 Signaling in AgRP Neurons Promotes Locomotor Activity. PhD thesis, Universität zu Köln.

Koch, Linda (2008). Genetic Analysis of Insulin and Insulin-like Growth Factor-1 Signaling in the Central Nervous System. PhD thesis, Universität zu Köln.

Haugg, Anke Maria (2008). Apoptosemodulation nach selektiver Inhibition der Cyclooxygenase-2 (COX-2) in humanen Lebertumorzelllinien. PhD thesis, Universität zu Köln.

Courts, Cornelius (2008). Molekularbiologische Analyse der Pathogenese primärer Lymphome des zentralen Nervensystems. PhD thesis, Universität zu Köln.

Kopecky, Caroline (2008). Rekombinante Immunrezeptoren als Biosensoren und signalabhängige Produzenten heterologer Produkte. PhD thesis, Universität zu Köln.

Yang, Fang (2008). Identification and characterization of interactors of RAX1 controlling shoot branching in Arabidopsis thaliana. PhD thesis, Universität zu Köln.

Zhao, Yang (2008). Immunity-Related GTPases in Cell-autonomous Resistance against Toxoplasma gondii. PhD thesis, Universität zu Köln.

Choorapoikayil, Suma (2008). Somitogenese im Zebrafisch: Die Interaktion zwischen Wnt und Delta/Notch Signalweg und die ripply vermittelte Termination der "clock" - Eine Untersuchung mittels der her1 und her7 Mutanten. PhD thesis, Universität zu Köln.

Hardt, Olaf Thorsten (2008). Molecular characterization of CNS interneurons: subtype diversity and fate determinants. PhD thesis, Universität zu Köln.

Yazdanpanah, Benjamin (2008). Funktionelle Analyse der Riboflavinkinase und ihre Rolle in TNF induzierten Signalkaskaden. PhD thesis, Universität zu Köln.

Mende, Ylva Christine (2008). Generierung und Charakterisierung von konditionalen knock-outs des Spleißfaktors Sfrs10 im Mausmodell. PhD thesis, Universität zu Köln.

Fischer, Jens A. A. (2008). Identification and functional characterization of mPDCA-1 as a novel antigen-uptake receptor on murine plasmacytoid dendritic cells enabling (cross-) priming of naïve CD4+ and CD8+ T cells. PhD thesis, Universität zu Köln.

Pongratz, Carola (2008). Potente HIV-gerichtete RNA-Interferenz mittels Selektion einer randomisierten lentiviralen shRNA-Bibliothek. PhD thesis, Universität zu Köln.

Schmidt, Patrick (2008). T-Zellen mit rekombinanten Immunrezeptoren lysieren autologe Tumorzellen und eliminieren Tumore durch gezielte Eradikation von Tumorstammzellen. PhD thesis, Universität zu Köln.

Nair, Jayan Nandanan (2008). A genetic screen for asymmetrically localized RNAs in Drosophila tracheal cells. PhD thesis, Universität zu Köln.

Uschkereit, Constanze (2008). Molekulare Charakterisierung der Rolle von CTNNB1-Mutationen bei der Entstehung von stromareichen Wilms Tumoren. Thesis Abstract, Universität zu Köln.

Simhadri, Venkateswara Rao (2008). Exosomal derived HLA-B-Associated Transcript-3 is a ligand for NKp30 and regulates Natural Killer Function in Innate and Adaptive Immune Responses. PhD thesis, Universität zu Köln.

Heinen, Tobias Johannes Adolf Josef (2008). Characterization of genes involved in recent adaptation. PhD thesis, Universität zu Köln.

Vukusic, Ivana (2008). Alternative pre-mRNA Splicing: Signals and Evolution. PhD thesis, Universität zu Köln.

Kwan, Yen Yen (2008). Phylogenomic analysis of metabotrophic P2Y receptor family and its expression in zebrafish, Danio rerio. PhD thesis, Universität zu Köln.

Weißhaar, Stefan Rene (2008). Proteolytische Kontrolle des Proteins der promyelozytischen Leukämie (PML) durch Modifikation mit dem Ubiquitin-verwandten Protein SUMO. PhD thesis, Universität zu Köln.

Schuhmann, Natascha (2008). Exploring the therapeutic potential of recombinant AAV vectors in stem cell and transplantation model systems for the treatment of heart diseases. PhD thesis, Universität zu Köln.

Martins Boucas, Jorge Miguel (2008). Engineering AAV-2 Targeting Vectors: A New Insertion Site and scFv Driven Vectors. PhD thesis, Universität zu Köln.

Majczak, Joanna (2008). Functional characterization of the mammalian iAAA protease subunit, YME1L. PhD thesis, Universität zu Köln.

Mauer, Jan (2008). The impact of myeloid cell-restricted insulin receptor deficiency on obesity-induced insulin resistance. PhD thesis, Universität zu Köln.

Ehses, Sarah Marie (2008). Functional analysis of mammalian m-AAA proteases. PhD thesis, Universität zu Köln.

Bouabe, Hicham (2008). Etablierung von Interleukin-10 (IL-10)-Reportermäusen zur Identifizierung der IL-10-produzierenden Zellen in vivo. PhD thesis, Universität zu Köln.

Merkwirth, Carsten (2008). Functional characterization of prohibitins by conditional inactivation in the mouse. PhD thesis, Universität zu Köln.

Augustin, Steffen (2008). Struktur und Funktionsmechanismus der mitochondrialen m-AAA-Protease aus S. cerevisiae. PhD thesis, Universität zu Köln.

Marques, Antonio (2008). Proteasome assembly and its regulation. Thesis Abstract, Universität zu Köln.

Schwager, Evelyn (2008). Segmentation of the spider Achaearanea tepidariorum investigated by gene expression and functional analysis of the gap gene hunchback. PhD thesis, Universität zu Köln.

Zivkovic, Daniel (2008). Neutral non-equilibrium population genetics. PhD thesis, Universität zu Köln.

Hilbrant, Maarten (2008). Development and Evolution of the Spider Silk Producing System. PhD thesis, Universität zu Köln.

Stahnke, Stefanie (2008). Die Funktion der viralen Phospholipase A2 während der Infektion des Adeno-assoziierten Virus 2. PhD thesis, Universität zu Köln.

Potta, Shiva Rama Krishna Prasad (2008). Generation and functional characterization of smooth muscle cells and cardiomyocytes derived from embryonic stem cells: Transcriptome analysis of contractile SMCs. Thesis Abstract, Universität zu Köln.

2007

Zielke, Norman (2007). Functional analysis of the cell cycle regulator Rca1 in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Vivekananthan, Nagarajavel (2007). H-NS mediated repression of the Escherichia coli bgl and proU operons. PhD thesis, Universität zu Köln.

Oprea, Gabriela-Elena (2007). T-plastin, a cytoskeletal protein with important function in axonal growth, acts as a modifier of spinal muscular atrophy. PhD thesis, Universität zu Köln.

Stemshorn, Kathryn (2007). The genomic Make-Up of a Hybrid Species - Analysis of the Invasive Cottus Lineage (Pisces, Teleostei) in the River Rhine system. PhD thesis, Universität zu Köln.

Chmielewski, Markus (2007). Antigen-spezifische T-Zellaktivierung durch rekombinante Immunrezeptoren: Evaluierung in einem immunkompetenten Maus-Modell. PhD thesis, Universität zu Köln.

Koppen, Mirko (2007). Reconstitution of mammalian m-AAA protease complexes with variable subunit composition in yeast mitochondria. PhD thesis, Universität zu Köln.

Paukner, Andreas (2007). Ein Regulationsnetzwerk aus H-NS und den Antirepressoren BglJ und LeuO. PhD thesis, Universität zu Köln.

Ramachandran, Vimal (2007). Defining the residues governing the mitotic destruction of Drosophila cyclin A. PhD thesis, Universität zu Köln.

Vellguth, Martin (2007). OrfMapper: A Web-Based Application for Querying and Visualizing Gene-Metadata. Thesis Abstract, Universität zu Köln.

Stratis, Athanasios (2007). Die Pathogene Rolle der Hautmakrophagen in einem Mausmodell mit einer Keratinozyteninduzierten und TNF-vermittelten Psoriasisähnlichen Hautentzündung. PhD thesis, Universität zu Köln.

Kleinridders, André (2007). Inactivation of Pleiotropic Regulator 1 reveals p53-dependent Control of Cell Proliferation and Apoptosis by the Pso4-complex. PhD thesis, Universität zu Köln.

Marques-Souza, Henrique (2007). Evolution of the gene regulatory network controlling trunk segmentation in insects. PhD thesis, Universität zu Köln.

Madhusudhan, Srinivasan (2007). The Mechanism and Modulation of H-NS Mediated Repression in Escherichia coli. PhD thesis, Universität zu Köln.

Rohde, Christoph (2007). Genetic and Functional Studies on the Conserved IRG (Immunity-related GTPase) Protein IRGC (CINEMA). PhD thesis, Universität zu Köln.

Mokkapati, Sharada (2007). Role of the Basement Membrane Proteins Nidogen-1 and -2 and Laminin-Nidogen Interaction in Physiology and Pathology of Skin. Thesis Abstract, Universität zu Köln.

Miteva, Maria (2007). Proteolytic Mechanisms Controlling SUMO Protein Modification. Thesis Abstract, Universität zu Köln.

Frommer, Friederike (2007). Exploring induction of T cell tolerance by B cells and dendritic cells upon conditional presentation of self antigen. Thesis Abstract, Universität zu Köln.

Song, Jian (2007). Exploring the influence of B cell receptor signaling components on the development and homeostasis of B cells. PhD thesis, Universität zu Köln.

Zeng, Jia (2007). Interferon-induced and Constitutive Expression of Immunity-related GTPases (IRG) in Mouse Tissues. PhD thesis, Universität zu Köln.

Rottscheidt, Ruth (2007). Gene Expression Divergence between Subspecies of the House Mouse and the Contribution to Reproductive Isolation. PhD thesis, Universität zu Köln.

Schulze, Silke (2007). Charakterisierung HAIRY MERISTEM-ähnlicher Gene und Identifizierung neuer Regulatoren der Seitentriebentwicklung in Arabidopsis thaliana. PhD thesis, Universität zu Köln.

Monfared, Parisa (2007). E2F1-mediated transcriptional regulation in vitro and in vivo. PhD thesis, Universität zu Köln.

Papic, Natasa (2007). Biochemical Analysis of Immunity-Related GTPase Irga6 In Vivo and In Vitro. The Role of the Myristoyl Group. PhD thesis, Universität zu Köln.

Hunn, Julia (2007). Evolution and Cellular Resistance Mechanisms of the Immunity-Related GTPases. PhD thesis, Universität zu Köln.

2006

Glanemann, Christoph (2006). In vivo and in vitro studies on proteasome assembly in Saccharomyces cerevisiae: Possible new roles for Hsp90, ATP, and the 19S regulator. Thesis Abstract, Universität zu Köln.

Metodiev, Metodi Dimitrov (2006). Role of prohibitins for proteolysis in yeast and murine mitochondria. PhD thesis, Universität zu Köln.

Mathew, Sam Jacob (2006). Identification and characterization of a genomic region involved in Drosophila gastrulation. PhD thesis, Universität zu Köln.

Hartwig, Sonja (2006). Proteomanalyse von Peroxisomen der Mausleber und ihre Beeinflußung durch Sterol Regulatory Element Binding Protein-1 (SREBP-1). Thesis Abstract, Universität zu Köln.

Bekpen, Cemalettin (2006). Evolutionary and functional studies of p47 GTPases involved in cell autonomous immunity. PhD thesis, Universität zu Köln.

Sieger, Dirk (2006). Su(H) mediated Notch signalling and the role of different her genes during zebrafish somitogenesis. PhD thesis, Universität zu Köln.

Kölsch, Verena (2006). T48 reguliert mit Fog/Concertina die Zellformveränderungen während der Mesoderminvagination in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Malik, Alock Suchitra (2006). Effect of reduced expression of sorcin on Ca2+ handling, in vivo heart function and transcriptional regulation. PhD thesis, Universität zu Köln.

Wurth, Stephanie (2006). Genetische und biochemische Charakterisierung der m-AAA-Proteasefunktion in Mitochondrien von Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Voolstra, Christian (2006). Evolution of gene expression between closely related taxa of Mus. PhD thesis, Universität zu Köln.

Uzunova, Kristina Marinova (2006). Proteolytic control of SUMO conjugates. Thesis Abstract, Universität zu Köln.

Vijayshankar, S.G. (2006). Inhibition of tumor growth by adenovirus-mediated expression of antiangiogenic and immunomodulatory proteins. PhD thesis, Universität zu Köln.

Thomas, Meike (2006). A Systematic Assessment of Signatures of Positive Selection Events in Natural Populations of the House Mouse. PhD thesis, Universität zu Köln.

Graef, Martin (2006). Mechanismen der Substraterkennung der mitochondrialen AAA-Protease Yme1 aus Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Baranowsky, Anke (2006). Untersuchungen zur Funktion der Basalmembranproteine Nidogen-1 und Nidogen-2 in der Haut. Thesis Abstract, Universität zu Köln.

Eckl, Katja Martina (2006). Molekulare und funktionelle Charakterisierung der kongenitalen Ichthyosen. Thesis Abstract, Universität zu Köln.

Brichta, Lars (2006). Molecular genetic investigations of histone deacetylase inhibitors as potential neurotherapeutics for autosomal recessive proximal spinal muscular atrophy (SMA). PhD thesis, Universität zu Köln.

Sattarzadeh Mohammadi, Amirali (2006). Identification and functional characterization of cargo binding sites of plant myosins. PhD thesis, Universität zu Köln.

Jaekel, Robert (2006). Regulation des Notch-Signalweges durch Lethal (2) giant discs (Lgd) und durch die Notch-Liganden. PhD thesis, Universität zu Köln.

Aranda, Manuel (2006). Functional analysis of a homolog of the pair-rule gene hairy in the short-germ beetle Tribolium castaneum. PhD thesis, Universität zu Köln.

Hochstein, Norbert (2006). Der epigenetische Status eines adenoviralen Transgenoms in Hamsterzellen. PhD thesis, Universität zu Köln.

Pierstorff, Nora (2006). Comparative and compositional analysis of cis-regulatory modules in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Baer, Magdalena (2006). A genetic screen for novel genes involved in tracheal development in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Kotagiri, Aswani Kumar (2006). Characterization of Zebrafish Class C Olfactory Receptor Gene repertoire. PhD thesis, Universität zu Köln.

Bohne, Felix (2006). Spezifische Elimination Hepatitis B Virus infizierter Hepatozyten durch modifizierte humane T-Zellen die einen chimären T-Zellrezeptor exprimieren und eine zytotoxische Immunantwort etablieren. Thesis Abstract, Universität zu Köln.

2005

Csiszar, Agnes (2005). Characterisation of Dof, an essential adaptor molecule in fibroblast growth factor signalling in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Neelakanta, Girish (2005). Genome variations in commensal and pathogenic E.coli. PhD thesis, Universität zu Köln.

Roth, Detlev (2005). Die Rolle von Plasmin in der Regulation der VEGF Aktivität während der Wundheilung: Untersuchungen im db/db Mausmodell. PhD thesis, Universität zu Köln.

Kaspar, Markus (2005). Charakterisierung der Funktion des Zink-Finger-Transkriptionsfaktors klumpfuss während der Entwicklung des peripheren Nervensystems bei Drosophila melanogaster. PhD thesis, Universität zu Köln.

Fried, Hans-Ulrich (2005). Geruchsstoffinduzierte Aktivität im Bulbus olfactorius der Maus: Aktivitätsmuster der olfaktorischen Rezeptorneuronen und Entwicklung eines Mausmodells zur aktivitätsabhängigen Markierung der Büschel- und Mitralzellen. PhD thesis, Universität zu Köln.

Corona, Teresa (2005). Funktionelle Untersuchungen zur sequenz-spezifischen Rekombination durch die Integrase des Bakteriophagen Lambda in eukaryotischen Zellen. PhD thesis, Universität zu Köln.

Vreden, Sebastian (2005). Expressionscharakterisierung und Identifizierung tumorrelevanter Gene beim humanen hepatozellulären Karzinom. PhD thesis, Universität zu Köln.

Schmiemann, Viola (2005). Methylierung als molekularbiologischer Marker zur Lungenkarzinom-Diagnostik. PhD thesis, Universität zu Köln.

Shah-Hosseini, Kijwasch (2005). NEJ2: Identifizierung und Charakterisierung eines neuen Proteins in Säugern und Saccharomyces cerevisiae, assoziiert mit Telomerstrukturen und der Nicht-Homologen Rekombination von DNA-Doppelstrangbrüchen. PhD thesis, Universität zu Köln.

Sukumaran, Sunil Kumar (2005). Development of genetically encoded cell type-specific activity markers for the mouse olfactory system. PhD thesis, Universität zu Köln.

Bungartz, Gerd (2005). Function of beta1 and beta7 Integrins in the Hematopoietic System. PhD thesis, Universität zu Köln.

Schnickmann, Stephanie (2005). Untersuchungen zu den spezifischen Auswirkungen von HGF im Vergleich zu KGF und GM-CSF auf primäre Keratinozyten in einem Kokultur-Wundheilungsmodell. PhD thesis, Universität zu Köln.

Parvanova, Iana Angelova (2005). Analysis of the role of the p47 GTPase IIGP1 in Resistance against Intracellular Pathogens. PhD thesis, Universität zu Köln.

Fröhlich, Marceli Stanislaw (2005). Funktionen molekularer Chaperone in der Qualitätskontrolle zytosolischer Proteine. PhD thesis, Universität zu Köln.

Palani Murugan, Rangasamy (2005). Regulation of polyamine biosynthesis in Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Scheel, Hartmut (2005). Comparative Analysis of the Ubiquitin-proteasome system in Homo sapiens and Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Dorn, Andreas (2005). Zelluläre Transkriptionsprofile nach Adenovirus Typ 12 Infektion oder Tumorinduktion. PhD thesis, Universität zu Köln.

Janßen, Ralf (2005). Untersuchungen zur molekularen Grundlage der Segmentbildun im Saftkugler Glomeris marginata (Myriapoda: Diplopoda). PhD thesis, Universität zu Köln.

Tom-Li-Stephen, (2005). Intracellular trafficking and MHC class II - mediated retrograde transport of zwitterionic polysaccharides. Thesis Abstract, Universität zu Köln.

Shankaran, Sunita Sathy (2005). her15, a novel gene with oscillating mRNA expression domains and its potential role in zebrafish somitogenesis. PhD thesis, Universität zu Köln.

Brondke, Holger (2005). Zur DNA Sequenz eines klinischen Isolaten ähnlichen HCMV (Humanes Cytomegalievirus) Stammes (Toledo): Veränderte Leserahmen durch zusätzliche Startkodons? PhD thesis, Universität zu Köln.

Bartsch, Michael (2005). Gene expression profiling leading to identification of essential components in EDS1/PAD4-regulated plant defence. PhD thesis, Universität zu Köln.

Nolden, Mark (2005). Funktion der m-AAA-Protease bei der Regulation mitochondrialer Translation. PhD thesis, Universität zu Köln.

Nolte, Arne W. (2005). Evolutionary genetic analysis of an invasive population of sculpins in the Lower Rhine. PhD thesis, Universität zu Köln.

Leonhardt, Ralf Max (2005). Molecular and Functional Characterization of Early and Late Checkpoints in the Quality Control of MHC Class I-Restricted Antigen Presentation. PhD thesis, Universität zu Köln.

Wallbrecht, Katrin (2005). Einfluß von SREBP-1 auf das mitochondriale Proteom der Leber. Thesis Abstract, Universität zu Köln.

Bentz, Kristine (2005). Brain Microenvironment and its Influence on Gene Expression and Differentiation of Murine Embryonic Stem Cells . Implications for Cell Replacement Strategies. PhD thesis, Universität zu Köln.

Müller, Dörte (2005). Studien zur Rolle von Blind-homologen MYB-Genen bei der Anlage von Achselmeristemen in Arabidopsis thaliana. PhD thesis, Universität zu Köln.

Czepe, Carmen (2005). Using microarray analysis to find novel genes involved in somitogenesis. PhD thesis, Universität zu Köln.

Eicker, Andrea (2005). Studien zur Charakterisierung der regulatorischen Elemente des LATERAL SUPPRESSOR Gens in Arabidopsis thaliana. PhD thesis, Universität zu Köln.

2004

Limburg, Endrik (2004). Molekulare und biochemische Charakterisierung des Wirk- und Resistenzmechanismus von TAN1057 in Staphylococcus aureus. PhD thesis, Universität zu Köln.

Matthey, Bärbel (2004). Entwicklung, Herstellung und In-vivo-Analysen neuer rekombinanter Immuntoxine sowie Untersuchungen des "Shedding-Phänomens" von Antigenen am Beispiel des Hodgkin-Lymphoms. Thesis Abstract, Universität zu Köln.

Rass, Ulrich (2004). Nachweis und Charakterisierung von Crp1p, einem neuen Holliday-Struktur bindenden Protein der Hefe Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Martens, Sascha (2004). Cell-Biology of Interferon Inducible GTPases. PhD thesis, Universität zu Köln.

Webb, Dennis (2004). Abortive Infektion von Hamsterzellen mit menschlichem Adenovirus Typ 12: Untersuchungen zur frühen Infektionsphase und Komplementierung des DNA-Replikationsblockes. PhD thesis, Universität zu Köln.

Alberts, Philipp (2004). Crosstalk between membrane trafficking and cell adhesion:The role of the SNARE protein TI-VAMP in neuronal morphogenesis. PhD thesis, Universität zu Köln.

Ihle, Sonja (2004). Detecting genes involved in selective sweeps within populations of the house mouse species complex - a multi-locus candidate gene approach -. PhD thesis, Universität zu Köln.

Neef, Klaus (2004). Homologe archaeale Holliday-Struktur auflösende Endonukleasen und ihre spezifischen Reaktionen mit cruciformer DNA. PhD thesis, Universität zu Köln.

Prpic, Nikola-Michael (2004). Vergleichende Studien zur Gliedmaßenentwicklung bei Arthropoden. PhD thesis, Universität zu Köln.

Hackbusch, Jana (2004). Untersuchung der TALE-Homöodomänen-Proteine in Arabidopsis thaliana. Identifizierung und Charakterisierung von Komponenten des TALE-Interaktions-Netzwerkes. PhD thesis, Universität zu Köln.

Clarenz, Oliver (2004). Studien zur Rolle des LATERAL SUPPRESSOR-Gens bei der Initiation von Achselmeristemen: Analyse von Doppelmutanten und Charakterisierung von Modifikatoren des las-4-Phänotyps. PhD thesis, Universität zu Köln.

Vieira Breitwieser, Otilia (2004). Leguminous Lectins Bind Non-specifically to DNA. PhD thesis, Universität zu Köln.

Pennartz, Sandra (2004). Gene expression analysis of neuronal precursors from adult mouse brain and differential screen for neural stem cell markers. PhD thesis, Universität zu Köln.

Savard, Joël (2004). A genomic approach to the study of Tribolium castaneum genetics, development & evolution. PhD thesis, Universität zu Köln.

Kambacheld, Melanie (2004). Charakterisierung mitochondrialer Peptidasen aus Saccharomyces cerevisiae. Thesis Abstract, Universität zu Köln.

Galluhn, Dominik (2004). Untersuchungen zur Assemblierung des ABC-Transporters Mdl1 in Mitochondrien von Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Wernet, Mathias F. (2004). Patterning the Retina of Drosophila Melanogaster for Color and Polarized Light Vision. PhD thesis, Universität zu Köln.

London, Markus Konrad Justin (2004). Regulation der Proteasombiogenese in Saccharomyces cerevisiae. PhD thesis, Universität zu Köln.

Müller, Regina Susanne (2004). Identifizierung und Charakterisierung Tumor-assoziierter Proteasen in der Epithelialen Karzinogenese. PhD thesis, Universität zu Köln.

Wunderlich, Frank Thomas (2004). Generation of inducible Cre systems for conditional gene inactivation in mice. PhD thesis, Universität zu Köln.

Saraiva, Luis Miguel Rodrigues (2004). A novel olfactory receptor gene family in teleost fish:phylogenomics, cellular localization and comparison with other olfactory receptor gene families. PhD thesis, Universität zu Köln.

2003

Schwarz-Herzke, Beryl (2003). Der Gastrointestinaltrakt als Eintrittspforte für fremde Makromoleküle: DNA und Proteine. PhD thesis, Universität zu Köln.

Pozhitkov, Alexander (2003). Molecular taxonomy. Bioinformatics and practical evaluation. PhD thesis, Universität zu Köln.

Schoppmeier, Michael (2003). Untersuchungen zu funktionell konservierten sowie divergenten Mechanismen des Segmentierungsprozesses der Arthropoden am Beispiel der Spinne Cupiennius salei. PhD thesis, Universität zu Köln.

Dove, Hilary Livia (2003). Neurogenesis in the millipede Glomeris marginata (Myriapoda: Diplopoda). PhD thesis, Universität zu Köln.

Eckert, Christoph (2003). Analyse der cis-regulatorischen Region des Gens hairy aus Triboleum castaneum. PhD thesis, Universität zu Köln.

Mi, Weiqian (2003). Wallerian degeneration and Wallerian-related axon loss in disease. PhD thesis, Universität zu Köln.

Berger, Joachim (2003). Molekulargenetische Analyse des Pax6-Gens in der Kortikogenese der Maus. PhD thesis, Universität zu Köln.

Zhu, Minyan (2003). A Genetic Screen for Genes Involved in the FGF Signalling Pathway in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Oberdörffer, Philipp (2003). Part I: B Cell Development and Function in Mice with a Targeted Lambda1 Light Chain Gene Insertion; Part II: Novel Approaches for Cre-mediated Inducible Gene Alteration in Mice. PhD thesis, Universität zu Köln.

Schenten, Dominik (2003). Analysis of the Function of DNA Polymerase Kappa and M17 in the Immune System. PhD thesis, Universität zu Köln.

Werber, Martin (2003). Vergleichende Analyse von Transkriptionsfaktor-Genfamilien am Beispiel der R2R3 MYB Transkriptionsfaktoren aus Ackerschmalwand (Arabidopsis thaliana) und Reis (Oryza sativa) mit bioinformatischen Methoden. PhD thesis, Universität zu Köln.

Steinfartz, Sebastian (2003). Molecular analysis of adaptive divergence: the impact of ecology on speciation in salamanders. Thesis Abstract, Universität zu Köln.

Schwering, Ines (2003). Genomweite Genexpressionsanalyse des klassischen Hodgkin-Lymphoms: Die verlorene B-Zellidentität. PhD thesis, Universität zu Köln.

Kurth, Julia Bernadette (2003). Charakterisierung Epstein-Barr Virus-infizierter B-Zellen der infektiösen Mononukleose: Virale Strategien zur Ausbreitung im B-Zellkompartiment und zur Etablierung einer lebenslangen Persistenz. PhD thesis, Universität zu Köln.

Naumann, Frauke (2003). Zur Struktur und Expression des Gens für das 5'-(CGG)n-3'-bindende Protein bei Mensch und Maus. PhD thesis, Universität zu Köln.

Dienemann, Axel (2003). Die Bedeutung der subzellulären Lokalisierung von Cyclin A in Drosophila melanogaster. PhD thesis, Universität zu Köln.

Uthaiah, Revathy C. (2003). Biochemical, Structural and Cellular Studies on IIGP1, a member of the p47 Family of GTPases. PhD thesis, Universität zu Köln.

Domazet-Loso, Tomislav (2003). Evolution of orphan genes in Drosophila. PhD thesis, Universität zu Köln.

Leyendeckers, Heike (2003). Vergleichende Analyse des Antikörper- und B-Zell-vermittelten Gedächtnisses. PhD thesis, Universität zu Köln.

2002

Çelik, Arzu (2002). Restricted and complementary expression patterns of EPH receptors and Ephrin ligands define potential interaction sites in the embryonic and adult olfactory system of Zebrafish, Danio Rerio. PhD thesis, Universität zu Köln.

Seher, Thomas-Christian (2002). Untersuchungen zur genetischen Kontrolle der Gastrulation von Drosophila melanogaster. PhD thesis, Universität zu Köln.

Paal, Jürgen Michael (2002). Molekulare Charakterisierung der Gro1 Region in Kartoffel, die Resistenz gegen den Nematoden Globodera rostochiensis vermittelt. PhD thesis, Universität zu Köln.

Horst, Alexander (2002). Isolation und Charakterisierung von Plasmazellen aus dem peripheren Blut mit besonderer Berücksichtigung IgE sezernierender Plasmazellen. PhD thesis, Universität zu Köln.

Jönsson, Kristina (2002). Conditional inactivation of the ubiquitin protein ligase Itch of the mouse. PhD thesis, Universität zu Köln.

Dzionek, Andrzej (2002). Humane Dendritische Zellen: Identifizierung und funktionelle Charakterisierung von neuen Oberflächenantigenen. PhD thesis, Universität zu Köln.

Bouabe, Hicham (2002). Charakterisierung der asymmetrischen Funktionalität der Nukleotidbindedomänen des ABC-Transporters TAP. Masters thesis, Universität zu Köln.